The CENTER-TBI Core dataset is a large dataset containing over 2,500 variables.
The main structure of the e-CRF consists of data related to:

  1. The patient type, injury, and enrollment
  2. The pre-hospital and presentation status
  3. Additional Ward or ICU data (depending on the type of patient)
  4. Additional MRI or HR ICU data (depending on the sub-studies performed)
  5. Transitions of care
  6. Treatment (labs, medication, surgery)
  7. Outcome assessments

Click to access the detailed structure. Within the structure, you can access the corresponding e-CRF forms.

Frequency Tables

We have been developing Frequency Tables for the CENTER-TBI data. These Frequency Tables do not lend themselves to analyses of the CENTER-TBI data, but serve to provide some orientating insight into the availability and distribution of data in the CENTER-TBI dataset. The Frequency Tables are available here.

For further insight into the CENTER-TBI dataset we also refer to the descriptive core paper of our Consortium:

Case-mix, care pathways, and outcomes in patients with traumatic brain injury in CENTER-TBI: a European prospective, multicentre, longitudinal, cohort study

Ewout W Steyerberg, Eveline Wiegers, Charlie Sewalt, Andras Buki, Giuseppe Citerio, Véronique De Keyser et al.

Lancet Neurol. 2019 Oct; 18 (10): 923-934. Doi: 10.1016/S1474-4422(19)30232-7

CENTER-TBI Variables

The complete list of CENTER-TBI variables available with their corresponding description is available below:

Variable Category Lookup values Description
AIS.InjAIS Original 0 == 0 No Injury
1 == 1 Minor
2 == 2 Moderate
3 == 3 Serious
4 == 4 Severe
5 == 5 Critical
6 == 6 Unsurvivable
In the original AIS classification of injury severity, the grading is from 1 (minor) to 6 (unsurvivable). We added a score of 0 to designate absence of injuries. This is the AIS score for body regions as specified by AIS.InjBodyRegion.
AIS.InjBodyRegion Original 1 == Externa
2 == Head and Neck-Other
3 == Brain Injury
4 == Cervical Spine
5 == Face
6 == Thorax/Chest
7 == Thoracic Spine
8 == Abdomen/Pelvic Contents
9 == Lumbar Spine
10 == Upper Extremities
11 == Lower Extremities
12 == Pelvic Girdle
Injuries and their severity are recorded according to a (modification of) the AIS. The AIS recognizes 6 main body regions. We included a further subdivision for some body regions, resulting in a total of 12 regions. For example, spine is not considered separately in the original AIS classification, but included under neck/chest and abdomen regions. For TBI, however, we considered it important to record spine separately.
AIS.InjDescription Original 1 == Brain Injury: Concussion
2 == Brain Injury: Contusions
3 == Brain Injury: EDH
4 == Brain Injury: Diffuse Injury
5 == Brain Injury: ASDH
6 == Brain Injury: Other
7 == Head and Neck-Other: Specify in comments box
8 == Cervical Spine: Fracture
9 == Cervical Spine: Dislocation
10 == Cervical Spine: Other
11 == Face: Maxillo-facial fracture le Fort I
12 == Face: Maxillo-facial fracture le Fort II
13 == Face: Maxillo-facial fracture le Fort III
14 == Face: Orbital fracture
15 == Face: Zygomatic arch fracture
16 == Face: Other
17 == Thorax/Chest: Rib fracture
18 == Thorax/Chest: Lung contusion
19 == Thorax/Chest: Cardiac contusion
20 == Thorax/Chest: Aorta dissection
21 == Thorax/Chest: Pneumo-thorax
22 == Thorax/Chest: Hemato-thorax
23 == Thorax/Chest: Other
24 == Thoracic Spine: Fracture
25 == Thoracic Spine: Dislocation
26 == Abdomen/Pelvic Contents: Spleen rupture
27 == Abdomen/Pelvic Contents: Liver rupture
28 == Abdomen/Pelvic Contents: Perforating abdominal injury
29 == Abdomen/Pelvic Contents: Kidney contusion
30 == Abdomen/Pelvic Contents: Retroperitoneal hematoma
31 == Abdomen/Pelvic Contents: Other
32 == Lumbar Spine: Fracture
33 == Lumbar Spine: Dislocation
34 == Lumbar Spine: Sacral fracture
35 == Lumbar Spine: Other
36 == Upper Extremities: Humerus fracture
37 == Upper Extremities: Radial and/or ulnar fracture
38 == Upper Extremities: Dislocation
39 == Upper Extremities: Hand
40 == Upper Extremities: Finger
41 == Lower Extremities: Femoral fracture
42 == Lower Extremities: Tibia plateau fracture
43 == Lower Extremities: Tibia fracture
44 == Lower Extremities: Ankle fracture
45 == Lower Extremities: Calcaneus fracture
46 == Lower Extremities: Metatarsal/tarsal fracture (toe fracture)
47 == Lower Extremities: Fibula fracture
48 == Pelvic Girdle: Pelvic fracture
49 == Pelvic Girdle: Hip fracture
50 == Pelvic Girdle: Hip dislocation
51 == Externa: Other
52 == Thoracic Spine: Other
53 == Upper Extremities: Other
54 == Lower Extremities: Other
55 == Pelvic Girdle: Other
List of body regions with 55 subcategories describing the injury.
AIS.InjDesOther Original Free text specifying the injury when AIS.InjDescription is "other"
Biomarkers.AliquotID1 Meta Biomarker Aliquot 1: Per patient 1x 9ml blood sample was collected in a serum separator tube. After 45 minutes (+/- 15) of coagulation at room temperature, it was centrifuged at 1500g for 10 minutes. 8x0,5ml of serum was then aliquoted into barcoded 1,8ml cryovials.
Biomarkers.AliquotID2 Meta Biomarker Aliquot 2: Per patient 1x 9ml blood sample was collected in a serum separator tube. After 45 minutes (+/- 15) of coagulation at room temperature, it was centrifuged at 1500g for 10 minutes. 8x0,5ml of serum was then aliquoted into barcoded 1,8ml cryovials.
Biomarkers.AliquotID3 Meta Biomarker Aliquot 3: Per patient 1x 9ml blood sample was collected in a serum separator tube. After 45 minutes (+/- 15) of coagulation at room temperature, it was centrifuged at 1500g for 10 minutes. 8x0,5ml of serum was then aliquoted into barcoded 1,8ml cryovials.
Biomarkers.AliquotID4 Meta Biomarker Aliquot 4: Per patient 1x 9ml blood sample was collected in a serum separator tube. After 45 minutes (+/- 15) of coagulation at room temperature, it was centrifuged at 1500g for 10 minutes. 8x0,5ml of serum was then aliquoted into barcoded 1,8ml cryovials.
Biomarkers.AliquotID5 Meta Biomarker Aliquot 5: Per patient 1x 9ml blood sample was collected in a serum separator tube. After 45 minutes (+/- 15) of coagulation at room temperature, it was centrifuged at 1500g for 10 minutes. 8x0,5ml of serum was then aliquoted into barcoded 1,8ml cryovials.
Biomarkers.AliquotID6 Meta Biomarker Aliquot 6: Per patient 1x 9ml blood sample was collected in a serum separator tube. After 45 minutes (+/- 15) of coagulation at room temperature, it was centrifuged at 1500g for 10 minutes. 8x0,5ml of serum was then aliquoted into barcoded 1,8ml cryovials.
Biomarkers.AliquotID7 Meta Biomarker Aliquot 7: Per patient 1x 9ml blood sample was collected in a serum separator tube. After 45 minutes (+/- 15) of coagulation at room temperature, it was centrifuged at 1500g for 10 minutes. 8x0,5ml of serum was then aliquoted into barcoded 1,8ml cryovials.
Biomarkers.AliquotID8 Meta Biomarker Aliquot 8: Per patient 1x 9ml blood sample was collected in a serum separator tube. After 45 minutes (+/- 15) of coagulation at room temperature, it was centrifuged at 1500g for 10 minutes. 8x0,5ml of serum was then aliquoted into barcoded 1,8ml cryovials.
Biomarkers.CentrifugationDate Meta Centrifugation Date of the Biomarker sample. These date/time values were provided by the sites on the “sample collection and processing forms” enclosed to the samples.
Biomarkers.CentrifugationTime Meta Centrifugation Time of the Biomarker sample. These date/time values were provided by the sites on the “sample collection and processing forms” enclosed to the samples.
Biomarkers.CollectionDate Meta Collection Date of the Biomarker sample. These date/time values were provided by the sites on the “sample collection and processing forms” enclosed to the samples.
Biomarkers.CollectionTime Meta Collection Time of the Biomarker sample. These date/time values were provided by the sites on the “sample collection and processing forms” enclosed to the samples.
Biomarkers.FreezerMinusEightyDate Meta All processed samples should be stored at -80°C with a needle to freezer time preferably within 2 hours. This variable reflects the date and time that the biomarker sample was stored in a minus 80 freezer. These date/time values were provided by the sites on the “sample collection and processing forms” enclosed to the samples.
Biomarkers.FreezerMinusEightyTime Meta All processed samples should be stored at -80°C with a needle to freezer time preferably within 2 hours. This variable reflects the date and time that the biomarker sample was stored in a minus 80 freezer. These date/time values were provided by the sites on the “sample collection and processing forms” enclosed to the samples.
Biomarkers.FreezerMinusTwentyDate Meta All processed samples should be stored at -80°C with a needle to freezer time preferably within 2 hours. However, if a -80°C freezer was not immediately accessible, samples could be temporarily (max 48 hours) stored in a minus 20°C non-frost-free freezer. This variable reflects the date and time that the biomarker sample was stored in a minus 20 freezer. These date/time values were provided by the sites on the “sample collection and processing forms” enclosed to the samples.
Biomarkers.FreezerMinusTwentyTime Meta All processed samples should be stored at -80°C with a needle to freezer time preferably within 2 hours. However, if a -80°C freezer was not immediately accessible, samples could be temporarily (max 48 hours) stored in a minus 20°C non-frost-free freezer. This variable reflects the date and time that the biomarker sample was stored in a minus 20 freezer. These date/time values were provided by the sites on the “sample collection and processing forms” enclosed to the samples.
Biomarkers.GFAP Meta Assay results for Glial fibrillary acidic protein [GFAP] - measured with an ultrasensitive immunoassay using digital array technology (Single Molecule Arrays, SiMoA)-based Human Neurology 4-Plex B assay (N4PB) run on the SR-X benchtop assay platform (Quanterix Corp., Lexington, MA) at the University of Florida (Gainesville, Florida).
Biomarkers.NFL Meta Assay results for Neurofilament protein-light (NFL) - measured with an ultrasensitive immunoassay using digital array technology (Single Molecule Arrays, SiMoA)-based Human Neurology 4-Plex B assay (N4PB) run on the SR-X benchtop assay platform (Quanterix Corp., Lexington, MA) at the University of Florida (Gainesville, Florida).
Biomarkers.NSE Meta Assay results for Neuron-specific enolase (NSE) - measured with a clinical-use automated system, using an electrochemiluminescence immunoassay kit (ECLIA) (Elecsys S100 and Elecsys NSE assays) run on the e 602 module of Cobas 8000 modular analyzer (Roche Diagnostics, Mannheim, Germany) at the University of Pecs (Pecs, Hungary).
Biomarkers.S100B Meta Assay results for S100 calciumbinding protein B (S100B) - measured with a clinical-use automated system, using an electrochemiluminescence immunoassay kit (ECLIA) (Elecsys S100 and Elecsys NSE assays) run on the e 602 module of Cobas 8000 modular analyzer (Roche Diagnostics, Mannheim, Germany) at the University of Pecs (Pecs, Hungary).
Biomarkers.SampleId Meta Per patient 1x 9ml blood sample was collected in a serum separator tube. After 45 minutes (+/- 15) of coagulation at room temperature, it was centrifuged at 1500g for 10 minutes. 8x0,5ml of serum was then aliquoted into barcoded 1,8ml cryovials (see also Biomarkers.AliquotID)
Biomarkers.Tau Meta Assay results for T-TAU - measured with an ultrasensitive immunoassay using digital array technology (Single Molecule Arrays, SiMoA)-based Human Neurology 4-Plex B assay (N4PB) run on the SR-X benchtop assay platform (Quanterix Corp., Lexington, MA) at the University of Florida (Gainesville, Florida).
Biomarkers.UCH-L1 Meta Assay results for Ubiquitin C-terminal hydrolase ubiquitin C-terminal hydrolase L1 (UCH-L1) - measured with an ultrasensitive immunoassay using digital array technology (Single Molecule Arrays, SiMoA)-based Human Neurology 4-Plex B assay (N4PB) run on the SR-X benchtop assay platform (Quanterix Corp., Lexington, MA) at the University of Florida (Gainesville, Florida).
Brainmonitoring.DataAvailable Meta Meta data from the High Resolution ICU data collected in a subcategory of patients in specific HR-ICU sites.
Brainmonitoring.DataCollectionSoftware Meta Meta data from the High Resolution ICU data collected in a subcategory of patients in specific HR-ICU sites.
Brainmonitoring.DataEndTime Meta Meta data from the High Resolution ICU data collected in a subcategory of patients in specific HR-ICU sites. Contains the time when the high resolution processing ended. This time has been adjusted to the midnight preceding the injury .
Brainmonitoring.DataProcessingSoftware Meta Meta data from the High Resolution ICU data collected in a subcategory of patients in specific HR-ICU sites.
Brainmonitoring.DataStartTime Meta Meta data from the High Resolution ICU data collected in a subcategory of patients in specific HR-ICU sites. Contains the time when the high resolution processing started. This time has been adjusted to the midnight preceding the injury .
Brainmonitoring.DateTimeFormat Meta Meta data from the High Resolution ICU data collected in a subcategory of patients in specific HR-ICU sites.
Brainmonitoring.Duration Meta Meta data from the High Resolution ICU data collected in a subcategory of patients in specific HR-ICU sites.
Brainmonitoring.FormatVersion Meta Meta data from the High Resolution ICU data collected in a subcategory of patients in specific HR-ICU sites.
Brainmonitoring.HDF5URL Meta URL to download high resolution ICU file
Brainmonitoring.InvalidValue Meta Meta data from the High Resolution ICU data collected in a subcategory of patients in specific HR-ICU sites.
CentralHaemostasis.AnnexinV_single_CD105_Annex_measurement Meta Measurement of CD105- and AnnexinV-positive microparticles for quantification of endothelial derived microparticles (EDMP) - results for endothelial derived microparticles (EDMP) (single positive Annexin V+) - using flow cytometry techniques. Citrated plasma sample was centrifuged for 20 min at 2,500 x g at RT. Supernatants were used to determine EDMP. Run on the BD Accuri C6 Plus flow cytometer (BD Biosciences; Heidelberg, Germany) at Institute for Research in Operative Medicine (IFOM, Cologne, Germany), University Witten/Herdecke.
CentralHaemostasis.AnnexinV_single_CD42b_Annex_measurement Meta Measurement of CD42b- and AnnexinV-positive microparticles for quantification of platelet-derived microparticles (PDMP) - results for platelet-derived microparticles (PDMP) (single positive Annexin V+) - using flow cytometry techniques. Citrated plasma sample was centrifuged for 20 min at 2,500 x g at RT. Supernatants were used to determine PDMP. Run on the BD Accuri C6 Plus flow cytometer (BD Biosciences; Heidelberg, Germany) at Institute for Research in Operative Medicine (IFOM, Cologne, Germany), University Witten/Herdecke.
CentralHaemostasis.CD105_AnnexinV_double_CD105_Annex_measurement Meta Measurement of CD105- and AnnexinV-positive microparticles for quantification of endothelial derived microparticles (EDMP) - results for endothelial derived microparticles (EDMP) (double positive CD105+/Annexin V+) - using flow cytometry techniques. Citrated plasma sample was centrifuged for 20 min at 2,500 x g at RT. Supernatants were used to determine EDMP. Run on the BD Accuri C6 Plus flow cytometer (BD Biosciences; Heidelberg, Germany) at Institute for Research in Operative Medicine (IFOM, Cologne, Germany), University Witten/Herdecke.
CentralHaemostasis.CD105_CD142_double_CD105_CD142_measurement Meta Measurement of CD105- and CD142-positive microparticles for quantification of endothelial derived microparticles (EDMP) - results for endothelial derived microparticles (EDMP) (double positive CD105+/CD142+) - using flow cytometry techniques. Citrated plasma sample was centrifuged for 20 min at 2,500 x g at RT. Supernatants were used to determine EDMP. Run on the BD Accuri C6 Plus flow cytometer (BD Biosciences; Heidelberg, Germany) at Institute for Research in Operative Medicine (IFOM, Cologne, Germany), University Witten/Herdecke.
CentralHaemostasis.CD105_CD62E_double_CD105_CD62E_measurement Meta Measurement of CD105- and CD62e-positive microparticles for quantification of endothelial derived microparticles (EDMP) - results for endothelial derived microparticles (EDMP) (double positive CD105+/CD62e+) - using flow cytometry techniques. Citrated plasma sample was centrifuged for 20 min at 2,500 x g at RT. Supernatants were used to determine EDMP. Run on the BD Accuri C6 Plus flow cytometer (BD Biosciences; Heidelberg, Germany) at Institute for Research in Operative Medicine (IFOM, Cologne, Germany), University Witten/Herdecke..
CentralHaemostasis.CD105_single_CD105_Annex_measurement Meta Measurement of CD105- and AnnexinV-positive microparticles for quantification of endothelial derived microparticles (EDMP) - results for endothelial derived microparticles (EDMP) (single positive CD105+) - using flow cytometry techniques. Citrated plasma sample was centrifuged for 20 min at 2,500 x g at RT. Supernatants were used to determine EDMP. Run on the BD Accuri C6 Plus flow cytometer (BD Biosciences; Heidelberg, Germany) at Institute for Research in Operative Medicine (IFOM, Cologne, Germany), University Witten/Herdecke.
CentralHaemostasis.CD105_single_CD105_CD142_measurement Meta Measurement of CD105- and CD142-positive microparticles for quantification of endothelial derived microparticles (EDMP) - results for endothelial derived microparticles (EDMP) (single positive CD105+) - using flow cytometry techniques. Citrated plasma sample was centrifuged for 20 min at 2,500 x g at RT. Supernatants were used to determine EDMP. Run on the BD Accuri C6 Plus flow cytometer (BD Biosciences; Heidelberg, Germany) at Institute for Research in Operative Medicine (IFOM, Cologne, Germany), University Witten/Herdecke.
CentralHaemostasis.CD105_single_CD105_CD62E_measurement Meta Measurement of CD105- and CD62e-positive microparticles for quantification of endothelial derived microparticles (EDMP) - results for endothelial derived microparticles (EDMP) (single positive CD105+) - using flow cytometry techniques. Citrated plasma sample was centrifuged for 20 min at 2,500 x g at RT. Supernatants were used to determine EDMP. Run on the BD Accuri C6 Plus flow cytometer (BD Biosciences; Heidelberg, Germany) at Institute for Research in Operative Medicine (IFOM, Cologne, Germany), University Witten/Herdecke.
CentralHaemostasis.CD142_single_CD105_CD142_measurement Meta Measurement of CD105- and CD142-positive microparticles for quantification of endothelial derived microparticles (EDMP) - results for endothelial derived microparticles (EDMP) (single positive CD142+) - using flow cytometry techniques. Citrated plasma sample was centrifuged for 20 min at 2,500 x g at RT. Supernatants were used to determine EDMP. Run on the BD Accuri C6 Plus flow cytometer (BD Biosciences; Heidelberg, Germany) at Institute for Research in Operative Medicine (IFOM, Cologne, Germany), University Witten/Herdecke.
CentralHaemostasis.CD42b_AnnexinV_double_CD42b_Annex_measurement Meta Measurement of CD42b- and AnnexinV-positive microparticles for quantification of platelet-derived microparticles (PDMP) - results for platelet-derived micro-particles (double positive for CD42b+/Annexin V+) - using flow cytometry techniques. Citrated plasma sample was centrifuged for 20 min at 2,500 x g at RT. Supernatants were used to determine PDMP. Run on the BD Accuri C6 Plus flow cytometer (BD Biosciences; Heidelberg, Germany) at Institute for Research in Operative Medicine (IFOM, Cologne, Germany), University Witten/Herdecke.
CentralHaemostasis.CD42b_CD62p_double_CD42b_CD62p_measurement Measurement of CD42b- and CD62p-positive microparticles for quantification of platelet-derived microparticles (PDMP) - results for platelet-derived microparticles (PDMP) (double positive CD42b+/CD62p+) - using flow cytometry techniques. Citrated plasma sample was centrifuged for 20 min at 2,500 x g at RT. Supernatants were used to determine PDMP. Run on the BD Accuri C6 Plus flow cytometer (BD Biosciences; Heidelberg, Germany) at Institute for Research in Operative Medicine (IFOM, Cologne, Germany), University Witten/Herdecke.
CentralHaemostasis.CD42b_single_CD42b_AnnexV_measurement Meta Measurement of CD42b and AnnexinV positive microparticles for quantification of platelet-derived microparticles (PDMP) - results for platelet-derived microparticles (PDMP) (single positive CD42b+) - using flow cytometry techniques. Citrated plasma sample was centrifuged for 20 min at 2,500 x g at RT. Supernatants were used to determine PDMP. Run on the BD Accuri C6 Plus flow cytometer (BD Biosciences; Heidelberg, Germany) at Institute for Research in Operative Medicine (IFOM, Cologne, Germany), University Witten/Herdecke.
CentralHaemostasis.CD42b_single_CD42b_CD62p_measurement Meta Measurement of CD42b- and CD62p-positive microparticles for quantification of platelet-derived microparticles (PDMP) - results for platelet-derived microparticles (PDMP) (single positive CD42b+) - using flow cytometry techniques. Citrated plasma sample was centrifuged for 20 min at 2,500 x g at RT. Supernatants were used to determine PDMP. Run on the BD Accuri C6 Plus flow cytometer (BD Biosciences; Heidelberg, Germany) at Institute for Research in Operative Medicine (IFOM, Cologne, Germany), University Witten/Herdecke.
CentralHaemostasis.CD62E_single_CD105_CD62E_measurement Meta Measurement of CD105- and CD62e-positive microparticles for quantification of endothelial derived microparticles (EDMP) - results for endothelial derived microparticles (EDMP) (single positive CD62e+) - using flow cytometry techniques. Citrated plasma sample was centrifuged for 20 min at 2,500 x g at RT. Supernatants were used to determine EDMP. Run on the BD Accuri C6 Plus flow cytometer (BD Biosciences; Heidelberg, Germany) at Institute for Research in Operative Medicine (IFOM, Cologne, Germany), University Witten/Herdecke.
CentralHaemostasis.CD62p_single_CD42b_CD62p_measurement Meta Measurement of CD42b- and CD62p-positive microparticles for quantification of platelet-derived microparticles (PDMP) - results for platelet-derived microparticles (PDMP) (single positive CD62p+) - using flow cytometry techniques. Citrated plasma sample was centrifuged for 20 min at 2,500 x g at RT. Supernatants were used to determine PDMP. Run on the BD Accuri C6 Plus flow cytometer (BD Biosciences; Heidelberg, Germany) at Institute for Research in Operative Medicine (IFOM, Cologne, Germany), University Witten/Herdecke.
CentralHaemostasis.CentrifugationDate Meta Centrifugation Date and Time of the central haemostatis sample. These date/time values were provided by the sites on the “sample collection and processing forms” enclosed to the samples.
CentralHaemostasis.CentrifugationTime Meta Centrifugation Date and Time of the central haemostatis sample. These date/time values were provided by the sites on the “sample collection and processing forms” enclosed to the samples.
CentralHaemostasis.CitrateAliquotID1 Meta Central Haemostasis citrate aliquot 1: The Haemostasis samples are complementary to the routine hospital tests and performed only in a selected number of sites. This involved the collection of blood into 1x 2.7ml potassium EDTA tube and 1x 10ml and 1x 5 ml sodium-citrate tubes (only for a limited number of ADM and ICU patients in selected sites). Post-op samples and Day 2 samples were also obtained in the same two sodium citrate tubes from a limited number of ICU patients (no potassium EDTA sample at these sampling points). Tubes were centrifuged at 1500g for 10 minutes after collection. 7x 1ml citrate plasma was then aliquoted into 1.8ml cryovials (see also CentralHaemostasis.SampleID)
CentralHaemostasis.CitrateAliquotID2 Meta Central Haemostasis citrate aliquot 2: The Haemostasis samples are complementary to the routine hospital tests and performed only in a selected number of sites. This involved the collection of blood into 1x 2.7ml potassium EDTA tube and 1x 10ml and 1x 5 ml sodium-citrate tubes (only for a limited number of ADM and ICU patients in selected sites). Post-op samples and Day 2 samples were also obtained in the same two sodium citrate tubes from a limited number of ICU patients (no potassium EDTA sample at these sampling points). Tubes were centrifuged at 1500g for 10 minutes after collection. 7x 1ml citrate plasma was then aliquoted into 1.8ml cryovials (see also CentralHaemostasis.SampleID)
CentralHaemostasis.CitrateAliquotID3 Meta Central Haemostasis citrate aliquot 3: The Haemostasis samples are complementary to the routine hospital tests and performed only in a selected number of sites. This involved the collection of blood into 1x 2.7ml potassium EDTA tube and 1x 10ml and 1x 5 ml sodium-citrate tubes (only for a limited number of ADM and ICU patients in selected sites). Post-op samples and Day 2 samples were also obtained in the same two sodium citrate tubes from a limited number of ICU patients (no potassium EDTA sample at these sampling points). Tubes were centrifuged at 1500g for 10 minutes after collection. 7x 1ml citrate plasma was then aliquoted into 1.8ml cryovials (see also CentralHaemostasis.SampleID)
CentralHaemostasis.CitrateAliquotID4 Meta Central Haemostasis citrate aliquot 4: The Haemostasis samples are complementary to the routine hospital tests and performed only in a selected number of sites. This involved the collection of blood into 1x 2.7ml potassium EDTA tube and 1x 10ml and 1x 5 ml sodium-citrate tubes (only for a limited number of ADM and ICU patients in selected sites). Post-op samples and Day 2 samples were also obtained in the same two sodium citrate tubes from a limited number of ICU patients (no potassium EDTA sample at these sampling points). Tubes were centrifuged at 1500g for 10 minutes after collection. 7x 1ml citrate plasma was then aliquoted into 1.8ml cryovials (see also CentralHaemostasis.SampleID)
CentralHaemostasis.CitrateAliquotID5 Meta Central Haemostasis citrate aliquot 5: The Haemostasis samples are complementary to the routine hospital tests and performed only in a selected number of sites. This involved the collection of blood into 1x 2.7ml potassium EDTA tube and 1x 10ml and 1x 5 ml sodium-citrate tubes (only for a limited number of ADM and ICU patients in selected sites). Post-op samples and Day 2 samples were also obtained in the same two sodium citrate tubes from a limited number of ICU patients (no potassium EDTA sample at these sampling points). Tubes were centrifuged at 1500g for 10 minutes after collection. 7x 1ml citrate plasma was then aliquoted into 1.8ml cryovials (see also CentralHaemostasis.SampleID)
CentralHaemostasis.CitrateAliquotID6 Meta Central Haemostasis citrate aliquot 6: The Haemostasis samples are complementary to the routine hospital tests and performed only in a selected number of sites. This involved the collection of blood into 1x 2.7ml potassium EDTA tube and 1x 10ml and 1x 5 ml sodium-citrate tubes (only for a limited number of ADM and ICU patients in selected sites). Post-op samples and Day 2 samples were also obtained in the same two sodium citrate tubes from a limited number of ICU patients (no potassium EDTA sample at these sampling points). Tubes were centrifuged at 1500g for 10 minutes after collection. 7x 1ml citrate plasma was then aliquoted into 1.8ml cryovials (see also CentralHaemostasis.SampleID)
CentralHaemostasis.CitrateAliquotID7 Meta Central Haemostasis citrate aliquot 7: The Haemostasis samples are complementary to the routine hospital tests and performed only in a selected number of sites. This involved the collection of blood into 1x 2.7ml potassium EDTA tube and 1x 10ml and 1x 5 ml sodium-citrate tubes (only for a limited number of ADM and ICU patients in selected sites). Post-op samples and Day 2 samples were also obtained in the same two sodium citrate tubes from a limited number of ICU patients (no potassium EDTA sample at these sampling points). Tubes were centrifuged at 1500g for 10 minutes after collection. 7x 1ml citrate plasma was then aliquoted into 1.8ml cryovials (see also CentralHaemostasis.SampleID)
CentralHaemostasis.CoagulationparameterFibrinogen_mg_dl Meta Assay results for standard coagulation test (Fibrinogen) - using a high sensitivity thromboplastin reagent (RecombiPasTin 2G (HemosIL®), Werfen, Bedford, USA) based on recombinant human tissue factor (RTF) for quantitative determination in citrated plasma of Prothrombin time (PT) and Fibrinogen. Run on the ACL TOP CTS 700 (Werfen, Barcelona, Spain). Coagulationparameter were performed by the Institute of Transfusion Medicine (ITM), Cologne-Merheim Medical Centre. Normal range: 276-471 Reference: HemosIL® package insert
CentralHaemostasis.CoagulationparameterINR Meta Assay results for standard coagulation test (INR) - using a high sensitivity thromboplastin reagent (RecombiPasTin 2G (HemosIL®), Werfen, Bedford, USA) based on recombinant human tissue factor (RTF) for quantitative determination in citrated plasma of Prothrombin time (PT) and Fibrinogen. Run on the ACL TOP CTS 700 (Werfen, Barcelona, Spain). Coagulationparameter were performed by the Institute of Transfusion Medicine (ITM), Cologne-Merheim Medical Centre.
CentralHaemostasis.CoagulationparameterPTT_sec Meta Assay results for standard coagulation test (PTT) - using the HemosIL® APTT-SP kit (Werfen, Bedford, USA). Run on the ACL TOP CTS 700 (Werfen; Barcelona, Spain). Coagulationparameter were performed by the Institute of Transfusion Medicine (ITM), Cologne-Merheim Medical Centre. Normal range: 23-36 Reference: HemosIL® package insert
CentralHaemostasis.CoagulationparameterQuick_procent Meta Assay results for standard coagulation test (Quick) - using a high sensitivity thromboplastin reagent (RecombiPasTin 2G (HemosIL®), Werfen, Bedford, USA) based on recombinant human tissue factor (RTF) for quantitative determination in citrated plasma of Prothrombin time (PT) and Fibrinogen. Run on the ACL TOP CTS 700 (Werfen, Barcelona, Spain). Coagulationparameter were performed by the Institute of Transfusion Medicine (ITM), Cologne-Merheim Medical Centre. Normal range: 70-130 Reference: HemosIL® package insert
CentralHaemostasis.CoagulationparameterThrombintime_sec Meta Assay results for standard coagulation test (Thrombin Time) - using the HemosIL® Thrombin Time kit (Werfen, Bedford, USA). Fibrinogen in the citrated plasma sample is converted to fibrin by the addition of purified bovine thrombin and the time required to form the clot is measured. Run on the ACL TOP CTS 700 (Werfen; Barcelona, Spain). Coagulationparameter were performed by the Institute of Transfusion Medicine (ITM), Cologne-Merheim Medical Centre. Normal range: 10-17 Reference: HemosIL® package insert
CentralHaemostasis.Coagulationparameter_Antithrombin_procent Meta Assay results for standard coagulation test (Antithrombin) - Antithrombin in human citrated plasma measured with an automated chromogenic assay technology using the HemosIL® aliquid Antithrombin kit (Werfen, Bedford, USA). Run on the ACL TOP CTS 700 (Werfen, Barcelona, Spain). Coagulationparameter were performed by the Institute of Transfusion Medicine (ITM), Cologne-Merheim Medical Centre. Normal range: 83-128 Reference: HemosIL® package insert
CentralHaemostasis.Coagulationparameter_Ddimers_ug_l Meta Assay results for standard coagulation test (D-Dimers) - using the HemosIL® D-Dimer Controls kit (Werfen, Bedford, USA). Run on the ACL TOP CTS 700 (Werfen, Barcelona, Spain). Coagulationparameter were performed by the Institute of Transfusion Medicine (ITM), Cologne-Merheim Medical Centre. Normal range: 0-232 Reference: HemosIL® package insert
CentralHaemostasis.Coagulationparameter_FactorIX_procent Meta Assay results for standard coagulation test (Factor IX) - human plasma immunodepleted of factor IX for the quantitaive determination of factor IX activity based on activated partial thromboplastin time (APTT) assay - using factor IX deficient plasma (Werfen, Barcelona, Spain). Run on the ACL TOP CTS 700 (Werfen, Barcelona, Spain). Coagulationparameter were performed by the Institute of Transfusion Medicine (ITM), Cologne-Merheim Medical Centre. Normal range: 65-150 Reference: HemosIL® package insert
CentralHaemostasis.Coagulationparameter_FactorVIII_procent Meta Assay results for standard coagulation test (Factor VIII) - using a Coamatic factor VIII kit (Chromogenix, Bedford, USA) for chromogenic determination of factor VIII activity in human citrated plasma. Run on the ACL TOP CTS 700 (Werfen; Barcelona, Spain). Coagulationparameter were performed by the Institute of Transfusion Medicine (ITM), Cologne-Merheim Medical Centre. Normal range: 50-150 Reference: HemosIL® package insert
CentralHaemostasis.Coagulationparameter_FactorV_procent Meta Assay results for standard coagulation test (Factor V) - human plasma immunodepleted of factor V for the quantitaive determination of factor V activity based on the prothrombin time (PT) assay - using factor V deficient plasma (Werfen, Bedford, USA). Run on the ACL TOP CTS 700 (Werfen, Barcelona, Spain). Coagulationparameter were performed by the Institute of Transfusion Medicine (ITM), Cologne-Merheim Medical Centre. Normal range: 62-139 Reference: HemosIL® package insert
CentralHaemostasis.Coagulationparameter_FactorXIIIAg_procent Meta Assay results for standard coagulation test (Factor XIII) - measured with Chromogenix factor XIII Antigen kit (Chromogenix, Bedford, USA) based on an automated latex enhanced immunoassay techniques. Run on the ACL TOP CTS 700 (Werfen; Barcelona, Spain). Coagulationparameter were performed by the Institute of Transfusion Medicine (ITM), Cologne-Merheim Medical Centre. Normal range: 75.2-154.8 Reference: Chromogenix® package insert
CentralHaemostasis.Coagulationparameter_Plasminogen_procent Meta Assay results for standard coagulation test (Plasminogen) - Plasminogen in human citrated plasma measured with an automated chromogenic assay technology using the HemosIL® Plasminogen kit (Werfen, Bedford, USA). Run on the ACL TOP CTS 700 (Werfen, Barcelona, Spain). Coagulationparameter were performed by the Institute of Transfusion Medicine (ITM), Cologne-Merheim Medical Centre. Normal range: 80-133 Reference: HemosIL® package insert
CentralHaemostasis.Coagulationparameter_ProteinC_procent Meta Assay results for standard coagulation test (Protein C) - Protein C in human citrated plasma measured with an automated chromogenic assay technology using the HemosIL® Protein C kit (Werfen, Bedford, USA). Run on the ACL TOP CTS 700 (Werfen; Barcelona, Spain). Coagulationparameter were performed by the Institute of Transfusion Medicine (ITM), Cologne-Merheim Medical Centre. Normal range: 70-140 Reference: HemosIL® package insert
CentralHaemostasis.Coagulationparameter_ProteinS_procent Meta Assay results for standard coagulation test (Protein S) - using the HemosIL® Protein S Activity kit (Werfen, Bedford, USA). Determination of the functional acitivty of free Protein S by measuring the degree of prolongation of a prothrombin time in the presence of recombinant human tissue factor, phospholipids, calcium ions and protein C. Run on the ACL TOP CTS 700 (Werfen, Barcelona, Spain). Coagulationparameter were performed by the Institute of Transfusion Medicine (ITM), Cologne-Merheim Medical Centre. Normal range: 63.5-149 Reference: HemosIL® package insert
CentralHaemostasis.Coagulationparameter_vWFAg_A_B_AB_procent Meta Assay results for standard coagulation test (von Willebrand Factor Antigen) in citrated plasma samples in patients with bloodtype A, B and AB - measured with the HemosIL® von Willebrand Antigen kit (Werfen, Bedford, USA) based on an automated latex enhanced immunoassay technique. Run on the ACL TOP CTS 700 (Werfen, Barcelona, Spain). Coagulationparameter were performed by the Institute of Transfusion Medicine (ITM), Cologne-Merheim Medical Centre. Normal range: 66-176 Reference: HemosIL® package insert
CentralHaemostasis.Coagulationparameter_vWFAg_BT_0_procent Meta Assay results for standard coagulation test (von Willebrand Factor Antigen) in citrated plasma samples in patients with bloodtype 0 - measured with the HemosIL® von Willebrand Antigen kit (Werfen, Bedford, USA) based on an automated latex enhanced immunoassay technique. Run on the ACL TOP CTS 700 (Werfen, Barcelona, Spain). Coagulationparameter were performed by the Institute of Transfusion Medicine (ITM), Cologne-Merheim Medical Centre. Normal range: 42-141 Reference: HemosIL® package insert
CentralHaemostasis.Coagulationparameter_vWFA_BT_0_procent Meta Assay results for standard coagulation test (von Willebrand Factor Activity) in citrated plasma samples in patients with bloodtype 0 - measured with the HemosIL® von Willebrand Activity kit (Werfen, Bedford, USA) based on an automated latex enhanced immunoassay technique. Run on the ACL TOP CTS 700 (Werfen; Barcelona, Spain). Coagulationparameter were performed by the Institute of Transfusion Medicine (ITM), Cologne-Merheim Medical Centre. Normal range: 40-126 Reference: HemosIL® package insert
CentralHaemostasis.Coagulationparameter_vWFA_BT_A_B_AB_procent Meta Assay results for standard coagulation test (von Willebrand Factor Activity) in citrated plasma samples in patients with bloodtype A, B and AB - measured with the HemosIL® von Willebrand Activity kit (Werfen, Bedford, USA) based on an automated latex enhanced immunoassay technique. Run on the ACL TOP CTS 700 (Werfen, Barcelona, Spain). Coagulationparameter were performed by the Institute of Transfusion Medicine (ITM), Cologne-Merheim Medical Centre. Normal range: 49-163 Reference: HemosIL® package insert
CentralHaemostasis.CollectionDate Meta Collection Date and Time of the central haemostatis sample. These date/time values were provided by the sites on the “sample collection and processing forms” enclosed to the samples.
CentralHaemostasis.CollectionTime Meta Collection Date and Time of the central haemostatis sample. These date/time values were provided by the sites on the “sample collection and processing forms” enclosed to the samples.
CentralHaemostasis.EDTAAliquotID1 Meta Central Haemostasis EDTA aliquot 1: The Haemostasis samples are complementary to the routine hospital tests and performed only in a selected number of sites. This involved the collection of blood into 1x 2.7ml potassium EDTA tube and 1x 10ml an d1x 5 ml sodium-citrate tubes (only for a limited number of ADM and ICU patients in selected sites). Post-op samples and Day 2 samples were also obtained in the same two sodium citrate tubes from a limited number of ICU patients (no potassium EDTA sample at these sampling points). Tubes were centrifuged at 1500g for 10 minutes after collection. 7x 1ml citrate plasma was then aliquoted into 1.8ml cryovials (see also CentralHaemostasis.CitrateAliquotID)
CentralHaemostasis.EDTAAliquotID2 Meta Central Haemostasis EDTA aliquot 2: The Haemostasis samples are complementary to the routine hospital tests and performed only in a selected number of sites. This involved the collection of blood inot 1x 2.7ml potassium EDTA tube and 1x 10ml an d1x 5 ml sodium-citrate tubes (only for a limited number of ADM and ICU patients in selected sites). Post-op samples and Day 2 samples were also obtained in the same two sodium citrate tubes from a limited number of ICU patients (no potassium EDTA sample at these sampling points). Tubes were centrifuged at 1500g for 10 minutes after collection. 7x 1ml citrate plasma was then aliquoted into 1.8ml cryovials (see also CentralHaemostasis.CitrateAliquotID)
CentralHaemostasis.Fibrinolysisregulator_Antiplasmin_Prozent Meta Assay results for Antiplasmin - measured with a colorimetric assay technology (STA-Stachrom®-TAFI-Kit, Stago; France). Measurement were performed at the Ludwig Boltzman Institute (Salzburg, Vienna). Normal range: 80-120 Reference: STA-Stachrom®-TAFI-Kit package insert
CentralHaemostasis.Fibrinolysisregulator_TAFI_procent Meta Assay results for Thrombin-Activatable Fibrinolysis Inhibitor (TAFI) -measured with a colorimetric assay technology (STA-Stachrom-TAFI-Kit, Stago; France). Measurement were performed at the Ludwig Boltzman Institute (Salzburg, Vienna). Detection limit of Stachrom-TAFI-Kit: 5-195
CentralHaemostasis.Fibrinolysis_FibrinogenMonomer_ug_ml Meta Assay results for fibrin monomers -using an immunoturbidimetric determination technology (STA - Liatest FM-Kit, Stago; France). Measurement were performed at the Ludwig Boltzman Institute (Salzburg, Vienna). Reference interval of Liatest FM-Kit of 6
CentralHaemostasis.FreezerMinusEightyDate Meta All processed haemostatis samples should be stored at -80°C with a needle to freezer time preferably within 2 hours. This variable reflects the date and time that the sample was stored in a minus 80 freezer. These date/time values were provided by the sites on the “sample collection and processing forms” enclosed to the samples.
CentralHaemostasis.FreezerMinusEightyTime Meta All processed haemostatis samples should be stored at -80°C with a needle to freezer time preferably within 2 hours. This variable reflects the date and time that the sample was stored in a minus 80 freezer. These date/time values were provided by the sites on the “sample collection and processing forms” enclosed to the samples.
CentralHaemostasis.FreezerMinusTwentyDate Meta All processed haemostatis samples should be stored at -80°C with a needle to freezer time preferably within 2 hours. However, if a -80°C freezer was not immediately accessible, samples could be temporarely (max 48 hours) stored in a minus 20°C non-frost-free freezer. This variable reflects the date and time that the sample was stored in a minus 20 freezer. These date/time values were provided by the sites on the “sample collection and processing forms” enclosed to the samples.
CentralHaemostasis.FreezerMinusTwentyTime Meta All processed haemostatis samples should be stored at -80°C with a needle to freezer time preferably within 2 hours. However, if a -80°C freezer was not immediately accessible, samples could be temporarely (max 48 hours) stored in a minus 20°C non-frost-free freezer. This variable reflects the date and time that the sample was stored in a minus 20 freezer. These date/time values were provided by the sites on the “sample collection and processing forms” enclosed to the samples.
CentralHaemostasis.PAI1_ng_ml Meta Assay results for Plasminogen-activator-inhibitor-1 (PAI-1) - using an ELISA Duo Set Kit from R&D Systems (Minneapolis, USA) based on the sandwich principle according to manufacturer’s instructions. EDTA plasma samples were used. Run on the EPOCH 2 (BioTek; Winooski, USA) microplate reader at Institute for Research in Operative Medicine (IFOM, Cologne, Germany), University Witten/Herdecke.
CentralHaemostasis.SampleId Meta The Haemostatis samples are complementary to the routine hospital tests and performed only in a selected number of sites. This involved the collection of blood into 1x 2.7ml potassium EDTA tube and 1x 10ml and 1x 5 ml sodium-citrate tubes (only for a limited number of ADM and ICU patients in selected sites). Post-op samples and Day 2 samples were also obtained in the same two sodium citrate tubes from a limited number of ICU patients (no potassium EDTA sample at these sampling points). Tubes were centrifuged at 1500g for 10 minutes after collection. 7x 1ml citrate plasma was then aliquoted into 1.8ml cryovials (see also CentralHaemostatis.CitrateAliquotID)
CentralHaemostasis.Syndecan1_pg_ml Meta Assay results for Syndecan-1 - using an ELISA Duo Set Kit from R&D Systems (Minneapolis, USA) based on the sandwich principle according to manufacturer’s instructions. EDTA plasma samples were used. Run on the EPOCH 2 (BioTek; Winooski, USA) microplate reader at Institute for Research in Operative Medicine (IFOM, Cologne, Germany), University Witten/Herdecke.
CentralHaemostasis.Thrombingeneration_ETP_nm_min Meta Assay results for endogenous thrombin potential (ETP) (STG®-BleedScreen, Stago, France) in citrated plasma - using a fluorogenic method (ST Genesia analyzer; Stago, France) - triggered by a low concentration of tissue factor. Measurement were performed at the Ludwig Boltzman Institute (Salzburg, Vienna).
CentralHaemostasis.Thrombingeneration_ETP_procent Meta Assay results for endogenous thrombin potential (ETP) (STG®-BleedScreen, Stago, France) in citrated plasma - using a fluorogenic method (ST Genesia analyzer, Stago; France) - triggered by a low concentration of tissue factor. Measurement were performed at the Ludwig Boltzman Institute (Salzburg, Vienna).
CentralHaemostasis.Thrombingeneration_LagTime_min Meta Assay results for quantitative determination of thrombin generation (STG®-BleedScreen, Stago, France) in citrated plasma (Lag Time) - using a fluorogenic method (ST Genesia analyzer, Stago; France) - triggered by a low concentration of tissue factor. Measurement were performed at the Ludwig Boltzman Institute (Salzburg, Vienna).
CentralHaemostasis.Thrombingeneration_LagTime_ratio Meta Assay results for quantitative determination of thrombin generation (STG®-BleedScreen, Stago, France) in citrated plasma (Lag Time) - using a fluorogenic method (ST Genesia analyzer, Stago; France) - triggered by a low concentration of tissue factor. Measurement were performed at the Ludwig Boltzman Institute (Salzburg, Vienna).
CentralHaemostasis.Thrombingeneration_PeakHeight_nm Meta Assay results for quantitative determination of thrombin generation (STG®-BleedScreen, Stago, France) in citrated plasma (Peak Height) - using a fluorogenic method (ST Genesia analyzer Stago; France) - triggered by a low concentration of tissue factor. Measurement were performed at the Ludwig Boltzman Institute (Salzburg, Vienna).
CentralHaemostasis.Thrombingeneration_PeakHeight_procent Meta Assay results for quantitative determination of thrombin generation (STG®-BleedScreen, Stago, France) in citrated plasma (Peak Height) - using a fluorogenic method (ST Genesia analyzer, Stago; France) - triggered by a low concentration of tissue factor. Measurement were performed at the Ludwig Boltzman Institute (Salzburg, Vienna).
CentralHaemostasis.Thrombingeneration_StartTail_min Meta Assay results for quantitative determination of thrombin generation in citrated plasma (Start Tail) - using a fluorogenic method (ST Genesia analyzer, Stago; France) - triggered by a low concentration of tissue factor. Measurement were performed at the Ludwig Boltzman Institute (Salzburg, Vienna).
CentralHaemostasis.Thrombingeneration_StartTail_ratio Meta Assay results for quantitative determination of thrombin generation in citrated plasma (Start Tail) - using a fluorogenic method (ST Genesia analyzer, Stago; France) - triggered by a low concentration of tissue factor. Measurement were performed at the Ludwig Boltzman Institute (Salzburg, Vienna).
CentralHaemostasis.Thrombingeneration_TimetoPeak_min Meta Assay results for quantitative determination of thrombin generation in citrated plasma (Time to Peak) - using a fluorogenic method (ST Genesia analyzer; Stago, France) - triggered by a low concentration of tissue factor. Measurement were performed at the Ludwig Boltzman Institute (Salzburg, Vienna).
CentralHaemostasis.Thrombingeneration_TimetoPeak_ratio Meta Assay results for quantitative determination of thrombin generation in citrated plasma (Time to Peak) - using a fluorogenic method (ST Genesia analyzer, Stago; France) - triggered by a low concentration of tissue factor. Measurement were performed at the Ludwig Boltzman Institute (Salzburg, Vienna).
CentralHaemostasis.Thrombingeneration_Vel_Index_nm_min Meta Assay results for quantitative determination of thrombin generation in citrated plasma (Velocity Index) - using a fluorogenic method (ST Genesia analyzer, Stago; France) - triggered by a low concentration of tissue factor. Measurement were performed at the Ludwig Boltzman Institute (Salzburg, Vienna).
CentralHaemostasis.Thrombingeneration_Vel_Index_procent Meta Assay results for quantitative determination of thrombin generation in in citrated plasma (Velocity index) - using a fluorogenic method (ST Genesia analyzer, Stago; France) - triggered by a low concentration of tissue factor. Measurement were performed at the Ludwig Boltzman Institute (Salzburg, Vienna).
CentralHaemostasis.Timepoints
CentralHaemostasis.UsedCitratAliquot1_Microparticles
CentralHaemostasis.UsedCitratAliquot1_ThrombinFibrinregu
CentralHaemostasis.UsedCitratAliquot2_Microparticles
CentralHaemostasis.UsedCitratAliquot2_ThrombinFibrinregu
CentralHaemostasis.UsedCitrateAliquot_Coagulationparameter
CentralHaemostasis.UsedEDTAAliquot1_ELISA
CentralHaemostasis.UsedEDTAAliquot2_ELISA
CentralHaemostasis.VECadherin_ng_ml Meta Assay results for VE-Cadherin - using an ELISA Duo Set Kit from R&D Systems (Minneapolis, USA) based on the sandwich principle according to manufacturer’s instructions. EDTA plasma samples were used. Run on the EPOCH 2 (BioTek; Winooski, USA) microplate reader at Institute for Research in Operative Medicine (IFOM, Cologne, Germany), University Witten/Herdecke.
CTMRI.CTAcuteSubdurHema Original 0 == No
1 == Small
2 == Large (mass)
88 == Unknown
Assessment by clinician/investigator whether or not in his/her interpretation an acute subdural hematoma is present. Also, the size (not quantified) is requested to be estimated.
CTMRI.CTAngulation Original 1 == No angulation (volume scan)
2 == Orbital-meatal line
99 == Other
This variable describes if a CT scan is performed with or without angulation. There are three options: no angulation (volume scan), orbital-meatal line and other. There is a risk of different interpretation, since there was no definition.
CTMRI.CTBasalCisternsAbsentCompressed Original 0 == No
1 == Yes
Assessment by clinician/investigator whether or not in his/her interpretation the basal cisterns are compressed.
CTMRI.CTContusion Original 0 == No
1 == Small
2 == Large (mass)
88 == Unknown
Assessment by clinician/investigator whether or not in his/her interpretation an intracerebral hematoma/contusion is present. Also, the size (not quantified) is requested to be estimated.
CTMRI.CTDeprSkullFract Original 0 == No
1 == Closed
2 == Open (compound)
Assessment by clinician/investigator whether or not in his/her interpretation a depressed skull fracture is present. In addition, when present, clinician/investigator has to document whether the fracture is associated with an open wound or not (compound vs closed)
CTMRI.CTDone Original This variable is populated when a CT has been made. Intent to perform a CT was an inclusion criterium for the study. All Images performed have been uploaded to the Imaging repository at Icometrix. Central review of initial and follow-up scans has been done by icometrix. Data of Central review are recorded separately. The variables below capture results of basic scoring by Investigators - these scores inform clinical decision making!
CTMRI.CTERReason Original 1 == GCS <= 14
2 == GCS = 15 + risk factors
3 == Head wound
4 == Exclusion of abnormalities prior to discharge
5 == Suspicion of maxillofacial injury
88 == Unknown
99 == Other
WHY question: reason for performing CT; only applicable to initial scan (presentation).
CTMRI.CTERReasonOther Original Specification, only applicable if "CTMRI.CTERReason" was "other"
CTMRI.CTExtraduralHema Original 0 == No
1 == Small
2 == Large (mass)
88 == Unknown
Assessment by clinician/investigator whether or not in his/her interpretation an acute extradural/epidural hematoma is present. Also, the size (not quantified) is requested to be estimated.
CTMRI.CTICLesionDAI Original 0 == No
1 == Yes
88 == Unknown
Assessment by clinician/investigator whether or not in his/her interpretation diffuse axonal injury is present.
CTMRI.CTIschemia Original 0 == No
1 == Single arterial territory
2 == Multiple territories
3 == Hemisphere
Assessment by clinician/investigator whether or not in his/her interpretation ischemia is present. Only applicable for clinical follow-up CT, not applicable to initial CT. In addition, the severity, in terms of how many arterial territories have ischemia, is requested to be answered.
CTMRI.CTManuf Original TOSH == Toshiba
SIEM == Siemens
PHIL == Philips
KONI == Konica Minolta
AGFA == Agfa
CARE == Carestream
GE == GE
HITA == Hitachi
99 == Other
This variable describes the CT scans manufacturer.
CTMRI.CTMidlineShift Original 0 == No
1 == Yes
Assessment by Investigator
CTMRI.CTMidlineShiftMeasure Original Assessment by Investigator
CTMRI.CTMRICompleteStatus Original INCNOSHOW == Incompletable - No Show
INCPT == Incompletable - Pt Factors
NOT == Queries Outstanding
COM == Complete
PRO == In Process
NOSTART == Not Started
This variable is populated when the CRF status is "complete".
CTMRI.CTMRIDate Original Date of Imaging captured in CRF
CTMRI.CTMRITime Original Time of imaging captured in CRF
CTMRI.CTNoOpMotiv Original 0 == No surgical lesion
1 == Lesion present, but Acceptable/good neurologic condition
2 == Lesion present, but Guideline adherence
3 == Lesion present, but Little/no mass effect
4 == Lesion present, but Not hospital policy
5 == Lesion present, but Extremely poor prognosis
6 == Lesion present, but Brain Death
7 == Lesion present, but Old age
8 == Lesion present, but Wish family, relative or Legal representative
88 == Unknown
99 == Lesion present, but Other
WHY question: documents reason for not having an indication for (intra)cranial surgery.
CTMRI.CTNoOpMotivOther Original Specification, only applicable if "CTMRI.CTNoOpMotiv" was "other"
CTMRI.CTPatientLocation Original ICU == ICU
ADMIS == Ward/Admission
ED == ER
This variable describes the in-hospital location of the patient when the CT-scan was performed and was not meant to describe the location of the CT-scanner. Three options: ER, Ward/Admission, ICU
CTMRI.CTReason Original ICUADM88 == Unknown
ICUADM99 == Other
LOP == Lack of improvement
IICP == (Suspicion of) Increasing ICP
CD == Clinical deterioration
POC == Post-operative control
SFU == Standard follow-up
This variable contains the main reason why a CT-scan, during hospital stay, was performed. One of following options: standard follow-up, post-operative control, clinical deterioration, (suspicion of) increasing ICP, lack of improvement, unknown, other (specified in CTMRI.CTReasonOther) The reason for making an early CT-scan/ER scan can be found in: CTMRI.CTERReason
CTMRI.CTReasonOther Original This variable contains the main reason why a CT-scan, during hospital stay, was performed. When the "other" option was selected in variable CTMRI.CTReason, investigators could write the reason in this free text variable. The reason for making an early CT-scan/ER scan can be found in: CTMRI.CTERReason
CTMRI.CTRiskFactorsERAgeGreatrThanEqual60 Original This variable describes the presence of risk factors (here: age greater than or equal to 60 years) for structural abnormalities on an early CT/MRI. Information for this variable was meant to be only entered for early CT, when CTMRI.CTERReason = "GCS = 15 + risk factors". However, due to the e-CRF lay-out, it will also be populated for patients with CTMRI.CTERReason is not "GCS = 15 + risk factors" or patients with an MRI.
CTMRI.CTRiskFactorsERAlterationOfConsc Original This variable describes the presence of risk factors (here: alteration of consciousness) for structural abnormalities on an initial/ER CT/MRI. Information for this variable was meant to be only entered for initial/ER CT, when CTMRI.CTERReason = "GCS = 15 + risk factors". However, due to the e-CRF lay-out, it will also be populated for patients with CTMRI.CTERReason is not "GCS = 15 + risk factors" or patients with an MRI.
CTMRI.CTRiskFactorsERAnticoagTx Original This variable describes the presence of risk factors (here: use of anticoagulant Tx ) for structural abnormalities on an early CT/MRI. Information for this variable was meant to be only entered for early CT, when CTMRI.CTERReason = "GCS = 15 + risk factors". However due to the e-CRF lay-out, it will also be populated for patients with CTMRI.CTERReason is not "GCS = 15 + risk factors" or patients with an MRI.
CTMRI.CTRiskFactorsERAnyNeuroDef Original This variable describes the presence of risk factors (here: 'any neurological deficit') for structural abnormalities on an initial/ER CT/MRI. Information for this variable was meant to be only entered for initial/ER CT, when CTMRI.CTERReason = "GCS = 15 + risk factors". However due to the e-CRF lay-out, it will also be populated for patients with CTMRI.CTERReason is not "GCS = 15 + risk factors" or patients with an MRI.
CTMRI.CTRiskFactorsERClinSignsOfFractSkullBaseVault Original This variable describes the presence of risk factors (here: 'clinical signs of fracture skull base or vault') for structural abnormalities on an initial/ER CT/MRI. Information for this variable was meant to be only entered for initial/ER CT, when CTMRI.CTERReason = "GCS = 15+risk factors". However, due to the e-CRF lay-out, it will also be populated for patients with CTMRI.CTERReason is not "GCS = 15 + risk factors" or patients with an MRI.
CTMRI.CTRiskFactorsERContusionFace Original This variable describes the presence of risk factors (here: 'contusion of the face') for structural abnormalities on an early CT/MRI. Information for this variable was meant to be only entered for early CT, when CTMRI.CTERReason = "GCS = 15 + risk factors". However due to the e-CRF lay-out, it will also be populated for patients with CTMRI.CTERReason is not "GCS = 15 + risk factors" or patients with an MRI.
CTMRI.CTRiskFactorsERFallFromAnyElev Original This variable describes the presence of risk factors (here: fall from any elevation) for structural abnormalities on an early CT/MRI. Information for this variable was meant to be only entered for early CT, when CTMRI.CTERReason = "GCS = 15 + risk factors". However, due to the e-CRF lay-out, it will also be populated for patients with CTMRI.CTERReason is not "GCS = 15 + risk factors" or patients with an MRI.
CTMRI.CTRiskFactorsERHeadache Original This variable describes the presence of risk factors (here: headache) for structural abnormalities on an early CT/MRI. Information for this variable was meant to be only entered for early CT, when CTMRI.CTERReason = "GCS = 15 + risk factors". However, due to the e-CRF lay-out, it will also be populated for patients with CTMRI.CTERReason is not "GCS = 15 + risk factors" or patients with an MRI.
CTMRI.CTRiskFactorsERIntoxication Original This variable describes the presence of risk factors (here: intoxication) for structural abnormalities on an initial/ER CT/MRI. Information for this variable was meant to be only entered for initial/ER CT, when CTMRI.CTERReason = "GCS = 15+risk factors". However due to the e-CRF lay-out, it will also be populated for patients with CTMRI.CTERReason is not "GCS = 15 + risk factors" or patients with an MRI.
CTMRI.CTRiskFactorsERLOC Original This variable describes the presence of risk factors (here: loss of consciousness) for structural abnormalities on an initial/ER CT/MRI. Information for this variable was meant to be only entered for initial/ER CT, when CTMRI.CTERReason = "GCS = 15 + risk factors". However, due to the e-CRF lay-out, it will also be populated for patients with CTMRI.CTERReason is not "GCS = 15 + risk factors" or patients with an MRI.
CTMRI.CTRiskFactorsEROther Original This variable describes the presence of risk factors (other reason, not specified elsewhere) for structural abnormalities on an early CT/MRI. Information for this variable was meant to be only entered for early CT, when CTMRI.CTERReason = "GCS = 15 + risk factors". However, due to the e-CRF lay-out, it will also be populated for patients with CTMRI.CTERReason is not "GCS = 15 + risk factors" or patients with an MRI.
CTMRI.CTRiskFactorsEROtherTxt Original This variable describes the presence of risk factors (other reason, not specified elsewhere: textfield) for structural abnormalities on an early CT/MRI. Information for this variable was meant to be only entered for early CT, when CTMRI.CTERReason = "GCS = 15 + risk factors". However, due to the e-CRF lay-out, it will also be populated for patients with CTMRI.CTERReason is not "GCS = 15 + risk factors" or patients with an MRI.
CTMRI.CTRiskFactorsERPhysEvidTraumaHeadSkull Original This variable describes the presence of risk factors (here: physical evidence of trauma to head/skull) for structural abnormalities on an initial/ER CT/MRI. Information for this variable was meant to be only entered for initial/ER CT, when CTMRI.CTERReason = "GCS = 15 + risk factors". However, due to the e-CRF lay-out, it will also be populated for patients with CTMRI.CTERReason is not "GCS = 15 + risk factors" or patients with an MRI.
CTMRI.CTRiskFactorsERPTAGreatrThanEqual4hrs Original This variable describes the presence of risk factors (here: PTA >= 4 hours) for structural abnormalities on an initial/ER CT/MRI. Information for this variable was meant to be only entered for initial/ER CT, when CTMRI.CTERReason = "GCS = 15 + risk factors". However, due to the e-CRF lay-out, it will also be populated for patients with CTMRI.CTERReason is not "GCS = 15 + risk factors" or patients with an MRI.
CTMRI.CTRiskFactorsERSeizure Original This variable describes the presence of risk factors (here: seizure) for structural abnormalities on an initial/ER CT/MRI. Information for this variable was meant to be only entered for initial/ER CT, when CTMRI.CTERReason = "GCS = 15 + risk factors". However, due to the e-CRF lay-out, it will also be populated for patients with CTMRI.CTERReason is not "GCS = 15 + risk factors" or patients with an MRI.
CTMRI.CTRiskFactorsERSignsFacialFract Original This variable describes the presence of risk factors (here: signs of facial fracture) for structural abnormalities on an initial/ER CT/MRI. Information for this variable was meant to be only entered for initial/ER CT, when CTMRI.CTERReason = "GCS = 15 + risk factors". However, due to the e-CRF lay-out, it will also be populated for patients with CTMRI.CTERReason is not "GCS = 15 + risk factors" or patients with an MRI.
CTMRI.CTRiskFactorsERVomit Original This variable describes the presence of risk factors (here: vomiting) for structural abnormalities on an initial/ER CT/MRI. Information for this variable was meant to be only entered for initial/ER CT, when CTMRI.CTERReason = "GCS = 15 + risk factors". However, due to the e-CRF lay-out, it will also be populated for patients with CTMRI.CTERReason is not "GCS = 15 + risk factors" or patients with an MRI.
CTMRI.CTRiskFactorsERVulnRoadUser Original This variable describes the presence of risk factors (here: vulnerable road users, like pedestrians or cyclists) for structural abnormalities on an early CT/MRI. Information for this variable was meant to be only entered for early CT, when CTMRI.CTERReason = "GCS = 15 + risk factors". However, due to the e-CRF lay-out, it will also be populated for patients with CTMRI.CTERReason is not "GCS = 15 + risk factors" or patients with an MRI.
CTMRI.CTScannerType Original 16 == 16-slice
32 == 32-slice
64 == 64-slice
99 == Other
128 == 128-slice
256 == 256-slice
320 == 320-slice
This variable specifies the type of CT-scanner by the number of slices.
CTMRI.CTSchedForOp Original 0 == No
1 == Yes
Whether or not the patient is scheduled for (intra)cranial surgery. The main aim here is to capture whether the clinical team taking care of the patient sees a neurosurgical indication.
CTMRI.CTSubarachnoidHem Original 0 == No
1 == Basal
2 == Cortical
3 == Basal and Cortical
Assessment by clinician/investigator whether or not in his/her interpretation subarachnoid hemorrhage is present. In addition, the location of the hemorrhage is requested to be answered.
CTMRI.CTType Original PCT == Perfusion CT
CTA == CT Angiography
CCT == Contrast CT
NCCT == Non-contrast CT
This variable describes the type of CT scan that has been made. Multiple options can be selected from: Non-contrast CT, Contrast CT, CT Angiography, Perfusion CT.
CTMRI.CTYesOpMotiv Original 1 == Emergency/life saving
2 == Clinical deterioration
3 == Mass effect on CT
4 == Radiological progression
5 == (Suspicion of) raised ICP
6 == Guideline adherence
7 == To prevent deterioration
8 == Depressed skull fracture
99 == Other
WHY question: documents reason for having an indication for (intra)cranial surgery.
CTMRI.CTYesOpMotivOther Original Free text if "CTMRI.CTYesOpMotiv" was marked as 'Other'. Relates to the WHY question: documents reason for having an indication for (intra)cranial surgery.
CTMRI.IcometrixImageId Meta Identifier generated for an imaging experiment when images are uploaded from site It's recommended to use: Imaging.CRFIcometrixImageId
CTMRI.IcometrixPassedQA Meta 0 == No
1 == Yes
Reflects if images uploaded from site passed QA of icometix. It's recommended to use: Imaging.CRFIcometrixPassedQA
CTMRI.IcometrixQADateTime Meta Date and time when central QA was done
CTMRI.IcometrixUploadDateTime Meta Date and time when the images were uploaded from site
CTMRI.InitialDataIcometrix Meta Reflects if the imaging data was initially loaded from Icometrix into the e-CRF (if not, it means the data in the e-CRF was entered manually by the study nurse) It's recommended to use "Imaging.CRFInitialDataIcometrix"
CTMRI.MRIDone Original This variable is populated when an MRI has been made. MR studies according to study protocol have been performed by selected sites. In addition, results of any MR performed for clinical reasons are captured in the e-CRF. Many of these clinical MR's have also been uploaded to Icometrix.
CTMRI.MRIERReason Original ER1 == ER only: Discrepancy between clinical symptomatology and (lack of) CT abnormalities
ER3 == ER only: Instead of CT (limiting radiation exposure)
ER2 == ER only: Suspicion non-metal foreign object
ER4 == ER only: Suspicion spinal cord lesion
88 == Unknown
99 == Other
This variable contains the main reason why an MRI, ultra-early MR (within 72 hrs), was performed. Possible options are ER only: Discrepancy between clinical symptomatology and (lack of) CT abnormalities; suspicion non­metal foreign object; instead of CT (limiting radiation exposure); suspicion spinal cord lesion; unknown; other (further specified in text field CTMRI.MRIERReasonOther. Reasons for clinical MRI's can be found in variable CTMRI.MRIReason
CTMRI.MRIERReasonOther Original This variable contains the main reason why an MRI, ultra-early MR (within 72 hrs), was performed, when in CTMRI.MRIERReason, the "other" option was chosen. This is a free text field. Reasons for clinical MRI's can be found in variable CTMRI.MRIReason
CTMRI.MRIManuf Original SIEM == Siemens
PHIL == Philips
GE == GE
TOSH == Toshiba
99 == Other
This variable describes the MRI-scan manufacturer. It's recommended to use "Imaging.CRFMRIManuf"
CTMRI.MRIPatientLocation Original ADMIS == Ward/Admission
ED == ER
ICU == ICU
This variable describes the in-hospital location of the patient when the MRI-scan was performed and was not meant to describe the location of the MRI-scanner. Three options: ER, Ward/Admission, ICU
CTMRI.MRIReason Original ICUADM3 == Detection of brainstem lesions
ICUADM2 == Standard Care
ICUADM1 == Discrepancy between CT and clinical condition
STUDYPROT == Study protocol
88 == Unknown
99 == Other
This variable contains the main reason why an MRI, during hospital stay, was performed. One of following options must be selected: discrepancy between CT and clinical condition, standard care, detection of brainstem lesions, study protocol, unknown, other (specified in CTMRI.MRIReasonOther). The reason for making an early MRI/ER MRI scan can be found in: CTMRI.MRIERReason It's recommended to use Imaging.CRFMRIReason
CTMRI.MRIReasonOther Original This variable contains the main reason why an MRI, during hospital stay, was performed, when in the variable CTMRI.MRIReason, the option "other" was chosen. This is a text field. The reason for making an early MRI/ER MRI scan can be found in: CTMRI.MRIERReason It's recommended to use Imaging.CRFMRIReasonOther
CTMRI.MRIResultPreExistAbnorm Original 0 == No
1 == Yes
88 == Unknown
This variable describes whether or not there are pre-existing abnormalities present on MRI scan (yes, no, unknown). Assessment by investigator and or physician. It’s recommended to use Imaging.CRFMRIResultPreExistAbnorm
CTMRI.MRIResultTraumaticAbnorm Original 0 == No
1 == Yes
88 == Unknown
This variable describes whether or not there are traumatic abnormalities present on MRI scan (yes, no, unknown). Assessment by investigator and/or physician. It’s recommended to use Imaging.CRFMRIResultTraumaticAbnorm
CTMRI.MRIScannerStrength Original This variable describes the MRI scanner strength. This is a text field. It’s recommended to use Imaging.CRFMRIScannerStrength
CTMRI.MRISequences Original PWI == PWI
MRSI == MRSI
DTI == DTI
SWI == SWI
GRE == GRE
DWI == DWI
FLAIR == FLAIR
T2 == T2
T1 == T1
99 == Other
This variable describes the MRI sequence. Options are: T1, T2, FLAIR, DWI, GRE, SWI, DTI, MRSI, PWI, Other. Multiple options can be selected. It’s recommended to use Imaging.CRFMRISequences
CTMRI.MRITraumAbnormASDH Original 0 == No
1 == Yes
88 == Unknown
This variable describes whether or not there is an acute subdural hematoma present on MRI scan (yes, no, unknown). Assessment by investigator and/or physician. It’s recommended to use Imaging.CRFMRITraumAbnormASDH
CTMRI.MRITraumAbnormContusion Original 0 == No
1 == Yes
88 == Unknown
This variable describes whether or not there is a contusion present on MRI scan (yes, no, unknown). Assessment by investigator and/or physician. It’s recommended to use Imaging.CRFMRITraumAbnormContusion
CTMRI.MRITraumAbnormDAI Original 0 == No
1 == Yes
88 == Unknown
This variable describes whether or not there is DAI (diffuse axonal injury) present on MRI scan (yes, no, unknown). Assessment by investigator and/or physician. It’s recommended to use Imaging.CRFMRITraumAbnormDAI
CTMRI.MRITraumAbnormDAILesionLocBrainstem Original 0 == No
1 == Yes
88 == Unknown
This variable describes whether or not there is a brain stem lesion present on MRI scan (yes, no, unknown). Assessment by investigator and/or physician. It’s recommended to use Imaging.CRFMRITraumAbnormDAILesionLocBrainstem
CTMRI.MRITraumAbnormDAILesionLocCorpusCallosum Original 0 == No
1 == Yes
88 == Unknown
This variable describes whether or not there is a corpus callosum lesion present on MRI scan (yes, no, unknown). Assessment by investigator and/or physician. It’s recommended to use Imaging.CRFMRITraumAbnormDAILesionLocCorpusCallosum
CTMRI.MRITraumAbnormDAILesionLocDiffuseWhiteMatter Original 0 == No
1 == Yes
88 == Unknown
This variable describes whether or not there is a lesion in diffuse white matter present on MRI scan (yes, no, unknown). Assessment by investigator and/or physician. It’s recommended to use Imaging.CRFMRITraumAbnormDAILesionLocDiffuseWhiteMatter
CTMRI.MRITraumAbnormDAINumLesions Original 1 == 1
2 == 2
3 == 3
4 == 4
5 == >= 5
This variable describes how many DAI lesions are present on MRI scan (1,2,3,4,>=5). Assessment by investigator and/or physician. It’s recommended to use Imaging.CRFMRITraumAbnormDAINumLesions
CTMRI.MRITraumAbnormEDH Original 0 == No
1 == Yes
88 == Unknown
This variable describes whether or not there is an epidural hematoma present on MRI scan (yes, no, unknown). Assessment by investigator and/or physician. It’s recommended to use Imaging.CRFMRITraumAbnormEDH
CTMRI.MRIType Original MRI == MRI
MRA == MRA
This variable describes the type of MRI scan that has been made. Options are: MRI, MRA It’s recommended to use Imaging.CRFMRIType
CTMRI.Timepoint Original CT Followup == CT Followup
CT Early == CT Early
CT Post-Op == CT Post-Op
MR Early == MR Early
This variable describes the timepoint of imaging. Options are: CT Early, CT Followup, CT Post­Op, MR Early CT early is considered "first CT". A central review was performed on all CT's. When a Central review is not available this can be due to: - Scan uninterpretable - Scan not available/performed/uploaded Reasons for scan not being available included: o Scan performed in referring hospital and images not available o Pediatric patient and MR performed instead of CT (reducing radiation risk) o Patient too uncooperative to undergo scan, and no indication for sedation.
CTMRI.XRayDone Original This variable is populated when an X-ray angiography has been done.
DailyTIL.TILCCSFDrainageVolume Original Specification of volume drained, only applicable if "DailyTIL.TILCSFDrainage" was "yes"
DailyTIL.TILCSFDrainage Original 0 == No
1 == Yes
Daily TIL: reflects if CSF drainage occurred yes or no
DailyTIL.TILDailyPhysConcSatisfNotDone Original Daily physician concerns are documented for 9 aspects rated on a scale of 1 (not concerned) to 10 (very concerned)
DailyTIL.TILDate Original Interpretation of ICP is not possible without knowledge on the level of therapy intensity employed for ICP control and/or for CPP management. TIL can be recorded in great detail and has commonly been performed on an hourly basis. Such detailed recording however, is resource intensive. Further, ICU practices have changed with most high grade interventions (such as metabolic suppression and temperature manipulation) now being used in a continuous fashion over periods of days or at least a large fraction of a day. Other discrete interventions (such as surgical decompression) happen as a single threshold event rather than as a repeated treatment. Given this context, the use of hourly recording of therapy intensity may be less relevant and there are doubts as to whether the data provided by hourly recording of TIL justifies the investment in time, particularly in the context of an increased (and probably increasing) burden of data collection in other areas (such as imaging and biomarkers). We therefore decided to record the therapy intensity level on a daily basis, under the presumption that this will offer a transparent and useful approach with the benefit of a lower burden than when hourly recording is performed. A novel TIL was developed to this purpose, which requires further validation. Preliminary data have been reported by Zuercher et al: Reliability and Validity of the Therapy Intensity Level Scale: Analysis of Clinimetric Properties of a Novel Approach to Assess Management of Intracranial Pressure in Traumatic Brain Injury; J Neurotrauma. 2016 Oct 1;33(19):1768-1774. Epub 2016 Feb 11. The specified treatment modalities and categories are compatible with the pediatric TIL proposed by Shore et al.: Shore P, Adelson PD, Kochanek P, et al. Reliability and validity of the pediatric intensity level of therapy (pilot) scale: A measure of the use of intracranial pressure-directed therapies. Crit Care Med. 2006;34:1981-1987. Possible chasnges in TIL over a 24 hr period are captured in the reporting of "hourly" values at 4 hr intervals.
DailyTIL.TILDobutamineDose Original Indicates the total dose of dobutamine administered (in mg.) if applicable. Calculated over a 24-hour period
DailyTIL.TILDopamineDose Original Indicates the total dose of dopamine administered (in mg.) if applicable. Calculated over a 24-hour period
DailyTIL.TILFactorsCaloricIntakeEnteralKcal Original Daily TIL: reflects the caloric intake via Enteral route in Kcal
DailyTIL.TILFactorsCaloricIntakeParenKcal Original Daily TIL: reflects the caloric intake via Parenteral route in Kcal
DailyTIL.TILFactorsCaloricIntakeRouteEnteral Original Enteral route The variables "parenteral" and "enteral route" are used to document if the patient received enteral feeding or not and if so, what the total number of Kcal was given by each route.
DailyTIL.TILFactorsCaloricIntakeRouteParen Original Parenteral The variables "parenteral" and "enteral route" are used to document if the patient received enteral feeding or not and if so, what the total number of Kcal was given by each route.
DailyTIL.TILFactorsCoagHemoglobAfterOtherUnitAmt Original Reflects the level of hemoglobin after transfusion in another unit than the standard g/dL (together with "DailyTIL.TILFactorsCoagHemoglobAfterOtherUnitSpecify")
DailyTIL.TILFactorsCoagHemoglobAfterOtherUnitSpecify Original 1 == mmol/L
99 == Other
Reflects the level of hemoglobin after transfusion in another unit than the standard g/dL (together with "DailyTIL.TILFactorsCoagHemoglobAfterOtherUnitAmt")
DailyTIL.TILFactorsCoagHemoglobBeforeOtherUnitAmt Original Reflects the level of hemoglobin before transfusion in another unit than the standard g/dL (together with "DailyTIL.TILFactorsCoagHemoglobBeforeOtherUnitSpecify")
DailyTIL.TILFactorsCoagHemoglobBeforeOtherUnitSpecify Original 1 == mmol/L
99 == Other
Reflects the level of hemoglobin before transfusion in another unit than the standard g/dL (together with "DailyTIL.TILFactorsCoagHemoglobBeforeOtherUnitAmt")
DailyTIL.TILFactorsCoagulation Original 0 == No
1 == Yes, for clinical reasons
2 == Yes, according to study protocol
88 == Unknown
A maximum of 4 "types" of treatment (drop down box) can be selected and entered under treatment 1-4. Details on volume/dose of the products administered should correspond to treatment 1-4 and be entered in the variable volume 1-4.
DailyTIL.TILFactorsCoagulationHemoglobinAfter Original Reflects the level of hemoglobin after transfusion in the standard unit (g/dL)
DailyTIL.TILFactorsCoagulationHemoglobinAfterNotDone Original Intended to document hemoglobin levels after blood transfusion, this variable would indicate that hemoglobin levels were not documented after transfusion; however, some investigators may have also marked this for patients who did not receive a blood transfusion
DailyTIL.TILFactorsCoagulationHemoglobinBefore Original Reflects the level of hemoglobin before transfusion in the standard unit (g/dL)
DailyTIL.TILFactorsCoagulationHemoglobinBeforeNotDone Original Intended to be only applicable in case the patient received a blood transfusion, however various investigators may have entered "not done", also for patient who did not receive a transfusion
DailyTIL.TILFactorsCoagulationType1 Original 1 == Packed red blood cell concentrates (pRBCs)
2 == Fresh whole blood
3 == Fresh frozen plasma (FFP)
4 == Freeze dried plasma / lypholized plasma
5 == Platelet concentrates
6 == PCC (prothrombin complex concentrates)
7 == Fibrinogen concentrate
8 == Albumine
9 == Recombinant factor FVIIa
10 == Tranexamic acid (TXA)
11 == Cryoprecipitate
12 == Desmopression (DDAVP)
13 == Factor XIII
14 == Calcium
Reflects the details on volume/dose of the products administered
DailyTIL.TILFactorsCoagulationType2 Original 1 == Packed red blood cell concentrates (pRBCs)
2 == Fresh whole blood
3 == Fresh frozen plasma (FFP)
4 == Freeze dried plasma / lypholized plasma
5 == Platelet concentrates
6 == PCC (prothrombin complex concentrates)
7 == Fibrinogen concentrate
8 == Albumine
9 == Recombinant factor FVIIa
10 == Tranexamic acid (TXA)
11 == Cryoprecipitate
12 == Desmopression (DDAVP)
13 == Factor XIII
14 == Calcium
Reflects the details on volume/dose of the products administered
DailyTIL.TILFactorsCoagulationType3 Original 1 == Packed red blood cell concentrates (pRBCs)
2 == Fresh whole blood
3 == Fresh frozen plasma (FFP)
4 == Freeze dried plasma / lypholized plasma
5 == Platelet concentrates
6 == PCC (prothrombin complex concentrates)
7 == Fibrinogen concentrate
8 == Albumine
9 == Recombinant factor FVIIa
10 == Tranexamic acid (TXA)
11 == Cryoprecipitate
12 == Desmopression (DDAVP)
13 == Factor XIII
14 == Calcium
Reflects the details on volume/dose of the products administered
DailyTIL.TILFactorsCoagulationType4 Original 1 == Packed red blood cell concentrates (pRBCs)
2 == Fresh whole blood
3 == Fresh frozen plasma (FFP)
4 == Freeze dried plasma / lypholized plasma
5 == Platelet concentrates
6 == PCC (prothrombin complex concentrates)
7 == Fibrinogen concentrate
8 == Albumine
9 == Recombinant factor FVIIa
10 == Tranexamic acid (TXA)
11 == Cryoprecipitate
12 == Desmopression (DDAVP)
13 == Factor XIII
14 == Calcium
Reflects the details on volume/dose of the products administered
DailyTIL.TILFactorsCoagulationVolume1 Original Reflects the details on volume/dose of the products administered
DailyTIL.TILFactorsCoagulationVolume2 Original Reflects the details on volume/dose of the products administered
DailyTIL.TILFactorsCoagulationVolume3 Original Reflects the details on volume/dose of the products administered
DailyTIL.TILFactorsCoagulationVolume4 Original Reflects the details on volume/dose of the products administered
DailyTIL.TILFactorsGenSuppCareDone Original 0 == No
1 == Yes
Reflects whether the patient received any blood transfusion, blood products and treatment of coagulopathy.
DailyTIL.TILFactorsGlucoseManagement Original 0 == No specific therapy
1 == Prophylactic
2 == Insulin administration to correct hyperglycemias
3 == Tight glycemic control (targeting blood glucose levels of 80-110mg/dL [4.4-6.1mmol/L])
Indicates whether glucose management was applied and if so, which therapy used (prophylactic, insulin administration of tight glycemic control).
DailyTIL.TILFever Original 0 == No
1 == Yes
Records for the Daily TIL whether there was treatment of fever (temperature <38°C) or spontaneous temperature of 34.5°C
DailyTIL.TILFeverHypothermia Original 0 == No
1 == Yes
Records for the Daily TIL whether there was hypothermia below 35°C
DailyTIL.TILFeverMildHypothermia Original 0 == No
1 == Yes
Records for the Daily TIL whether there was mild hypothermia for ICP control with a lower limit of 35°C.
DailyTIL.TILFluidBalanceNotDone Original Indicates that the Fluid Balance was not done.
DailyTIL.TILFluidCalcStartDate Original Start date Fluid Balance calculation.
DailyTIL.TILFluidCalcStartTime Original Start Time Fluid Balance calculation.
DailyTIL.TILFluidCalcStopDate Original Stop date Fluid Balance calculation.
DailyTIL.TILFluidCalcStopTime Original Stop Time Fluid Balance calculation.
DailyTIL.TILFluidColloids Original 0 == No
1 == Yes
88 == Unknown
Indicates whether colloids were administered with regard to Fluid Balance.
DailyTIL.TILFluidColloidsTotalVolume Original Total volume of colloids administered (in ml)
DailyTIL.TILFluidColloidsType Original 1 == Albumin 5%
2 == Albumin 20%
3 == Dextran
4 == Gelatin (e.g. gelofusion)
5 == HES (hydroxyethyl starches)
6 == Tetrastarches (e.g. HES 130/04)
Type of colloids administered
DailyTIL.TILFluidIn Original Recorded preferably over 24-hour period, exact details to be derived from start and stop date/time for calculation
DailyTIL.TILFluidLoading Original 0 == No
1 == Yes
Records for the Daily TIL whether there was fluid loading for maintenance of cerebral perfusion.
DailyTIL.TILFluidLoadingVasopressor Original 0 == No
1 == Yes
Records for the Daily TIL whether there was vasopressor therapy required for management of cerebral perfusion
DailyTIL.TILFluidOutCSFDrain Original Daily TIL - Number of fluid out: CSF drainage in ml
DailyTIL.TILFluidOutGastric Original Daily TIL - Number of fluid out: Gastic loss in ml
DailyTIL.TILFluidOutOther Original Daily TIL - Number of fluid out: other fluid (than Urine, Gastic loss or CSF drainage) in ml
DailyTIL.TILFluidOutUrine Original Daily TIL - Number of fluid out: Urine in ml
DailyTIL.TILFluidsRenalReplacement Original 0 == No
1 == Yes
Indicates for the fluid balance whether there was a need for renal replacement therapy.
DailyTIL.TILHyperosmolarThearpy Original 0 == No
1 == Yes
Records for the Daily TIL whether there was Hyperosmolar therapy with mannitol up to 2 g/kg/24 hours
DailyTIL.TILHyperosomolarTherapyHigher Original 0 == No
1 == Yes
Records for the Daily TIL whether there was Hyperosmolar therapy with hypertonic saline > 0.3 g/kg/24 hours
DailyTIL.TILHyperosomolarTherapyHypertonicLow Original 0 == No
1 == Yes
Records for the Daily TIL whether there was Hyperosmolar therapy with hypertonic saline up to 0.3 g/kg/24 hours
DailyTIL.TILHyperosomolarTherapyMannitolGreater2g Original 0 == No
1 == Yes
Records for the Daily TIL whether there was Hyperosmolar therapy with mannitol > 2 g/kg/24 hours
DailyTIL.TILHypertonicSalineDose Original Indicates the total dose of hypertonic saline administered (in g.) if applicable. Calculated over a 24-hour period.
DailyTIL.TILHyperventilation Original 0 == No
1 == Yes
Records for the Daily TIL whether there was Mild hypocapnia for ICP control [PaCO2 4.6 - 5.3 kPa (35 - 40 mmHg)]
DailyTIL.TILHyperventilationIntensive Original 0 == No
1 == Yes
Records for the Daily TIL whether there was Intensive hypocapnia for ICP control [PaCO2 < 4.0 kPa (30 mmHg)]
DailyTIL.TILHyperventilationModerate Original 0 == No
1 == Yes
Records for the Daily TIL whether there was Moderate hypocapnia for ICP control [PaCO2 4.0 - 4.5 kPa (30 - 35 mmHg)]
DailyTIL.TILICPSurgery Original 0 == No
1 == Yes
Records for the Daily TIL whether there was an intracranial operation for progressive mass lesion, not scheduled on admission
DailyTIL.TILICPSurgeryDecomCranectomy Original 0 == No
1 == Yes
Records for the Daily TIL whether there was a Decompressive Craniectomy
DailyTIL.TILMannitolDose Original Indicates the total dose of Mannitol administered (in g.) if applicable. Calculated over a 24-hour period
DailyTIL.TILNoradrenalineDose Original Indicates the total dose of Noradrenaline administered (in mg.) if applicable. Calculated over a 24-hour period
DailyTIL.TILOtherDose Original Indicates the dose (in mg.) of other vasopressors drugs administered (if applicable)
DailyTIL.TILOtherTxt Original Indicates which other vasopressors drugs was administered (if applicable)
DailyTIL.TILOtherVaso Original 0 == No
1 == Yes
Indicates whether any other Vasopressor drug was administered (other than Dobutamine, Dopamine, Noradrenaline or Phenylephrine)
DailyTIL.TILPhenylephrineDose Original Indicates the total dose of phenylephrine administered (in mg.) if applicable. Calculated over a 24-hour period
DailyTIL.TILPhysicianConcernsContusionpregression Original 1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
7 == 7
8 == 8
9 == 9
10 == 10
Reflects daily the physician concern and satisfaction with regard to contusion progression. Scales from 1 (not concerned) to 10 (very concerned)
DailyTIL.TILPhysicianConcernsCPP Original 1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
7 == 7
8 == 8
9 == 9
10 == 10
Reflects daily the physician concern and satisfaction with regard to CPP. Scales from 1 (not concerned) to 10 (very concerned)
DailyTIL.TILPhysicianConcernsEpilepsy Original 1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
7 == 7
8 == 8
9 == 9
10 == 10
Reflects daily the physician concern and satisfaction with regard to epilepsy. Scales from 1 (not concerned) to 10 (very concerned)
DailyTIL.TILPhysicianConcernsFocalSwelling Original 1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
7 == 7
8 == 8
9 == 9
10 == 10
Reflects daily the physician concern and satisfaction with regard to focal swelling. Scales from 1 (not concerned) to 10 (very concerned)
DailyTIL.TILPhysicianConcernsHematomaProgression Original 1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
7 == 7
8 == 8
9 == 9
10 == 10
Reflects daily the physician concern and satisfaction with regard to hematoma progression. Scales from 1 (not concerned) to 10 (very concerned)
DailyTIL.TILPhysicianConcernsHypoperfusion Original 1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
7 == 7
8 == 8
9 == 9
10 == 10
Reflects daily the physician concern and satisfaction with regard to suspected hypoperfusion. Scales from 1 (not concerned) to 10 (very concerned)
DailyTIL.TILPhysicianConcernsICP Original 1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
7 == 7
8 == 8
9 == 9
10 == 10
Reflects daily the physician concern and satisfaction with regard to ICP. Scales from 1 (not concerned) to 10 (very concerned)
DailyTIL.TILPhysicianConcernsIntracranialInfection Original 1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
7 == 7
8 == 8
9 == 9
10 == 10
Reflects daily the physician concern and satisfaction with regard to intracranial infections. Scales from 1 (not concerned) to 10 (very concerned)
DailyTIL.TILPhysicianConcernsVasospasm Original 1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
7 == 7
8 == 8
9 == 9
10 == 10
Reflects daily the physician concern and satisfaction with regard to vasospasm. Scales from 1 (not concerned) to 10 (very concerned)
DailyTIL.TILPhysicianOverallSatisfaction Original 0 == Not at all
1 == Slightly
2 == Moderately
3 == Quite
4 == Very
This variable aims to capture the overall satisfaction of the physician with the clinical course of this patient; "not at all satisfied" would indicate that the patient did much more poorly than expected; "very satisfied" would indicate that the patient did much better than expected. Physician satisfaction should be assessed on a daily basis,
DailyTIL.TILPhysicianOverallSatisfactionSurvival Original 1 == Much worse
2 == A little worse
3 == Unchanged
4 == A little better
5 == Much better
This variable aims to capture the opinion of the treating physician as to whether the short time survival change have chnged in comparision to the previous assessment
DailyTIL.TILPhysicianSatICP Original 1 == Not at all
2 == Slightly
3 == Moderate
4 == Quite
5 == Very
77 == N/A (no ICP monitoring)
Documents physician satisfaction with ICP control
DailyTIL.TILPosition Original 0 == No
1 == Yes
Records for the Daily TIL whether there was head elevation for ICP control
DailyTIL.TILPositionNursedFlat Original 0 == No
1 == Yes
Records for the Daily TIL whether there was a patient position of Nursed flat (180°C) for CPP management
DailyTIL.TILReasonForChange Original 0 == No change
1 == Intensified: Clinical deterioration
2 == Intensified:Suspicion of increased of ICP (not measured)
3 == Intensified:Increased ICP (documented)
4 == Intensified:Clinical decision to target other mechanism
5 == Intensified:Change of doctor (different shift)
6 == Decreasing:Clinical improvement
7 == Decreasing:Adequate control over ICP
8 == Decreasing:Upper treatment limit reached/past
9 == Decreasing:Further treatment considered futile
10 == Decreasing:Change of doctor (different shift)
Reflects the reason for change in TIL therapy over the day.
DailyTIL.TILSedation Original 0 == No
1 == Yes
Records for the Daily TIL whether there was sedation (low dose as required for mechanical ventilation)
DailyTIL.TILSedationHigher Original 0 == No
1 == Yes
Records for the Daily TIL whether there was a higher dose sedation for ICP control (not aiming for burst supression)
DailyTIL.TILSedationMetabolic Original 0 == No
1 == Yes
Records for the Daily TIL whether there was metabolic suppression for ICP control with high dose barbiturates or propofol
DailyTIL.TILSedationNeuromuscular Original 0 == No
1 == Yes
Records for the Daily TIL whether there was neuromuscular blockade (paralysis)
DailyTIL.TILSedationScaleUsed Original 0 == No
1 == Yes
77 == N/A
Reflects with regard to sedation management whether a sedation scale (SAS, RASS, MASS, Ramsay, etc) was used to adjust sedatives?
DailyTIL.TILSedativesInterrupted Original 0 == No
1 == Yes
77 == N/A
Reflects with regard to sedation management whether infusions of sedatives (opioids) were interrupted during the day if the patient was receiving any.
DailyTIL.TILTherapyIntensityNotDone Original Marked if Daily TIL was not done for a patient
DailyTIL.TILTime Original Time of Daily TIL records. See also "DailyTIL.TILDate"
DailyTIL.TotalTIL Calculated Calculated centrally - 24 hour TILS as the worst sum TILs for each day for the ICU timepoints (day 1-7, 10, 14, 21 and 28)
FollowUp.CTAngulation Original 1 == No angulation (volume scan)
2 == Orbital-meatal line
99 == Other
Reflects the angulation of the Follow up CT.
FollowUp.CTAtrophy Original 0 == No
D == Diffuse
F == Focal
88 == Unknown
CT parameters scored by the investigator: reflects the Atrophy of the Follow up CT.
FollowUp.CTHydrocephalus Original 0 == No
1 == Yes
88 == Unknown
CT parameters scored by the investigator: reflects if there was hydrocephalus or not on the Follow up CT.
FollowUp.CTManuf Original AGFA == Agfa
CARE == Carestream
GE == GE
HITA == Hitachi
KONI == Konica Minolta
PHIL == Philips
SIEM == Siemens
TOSH == Toshiba
99 == Other
Manufacturer of the CT scanner used
FollowUp.CTMidlineShift Original 0 == No
1 == Yes
CT parameters scored by the investigator: reflects if there was midline shift on the Follow up CT.
FollowUp.CTMidlineShiftMeasure Original CT parameters scored by the investigator: reflects the volume in mm if there was a midline shift on the Follow up CT Check also "FollowUp.CTMidlineShift"
FollowUp.CTMRIDate Original Imaging date captured in the CRF for followup images
FollowUp.CTMRITime Original Imaging time captured in CRF for followup images
FollowUp.CTReason Original RFU == Routine follow-up
LOP == Absence of or slow improvement
CD == Clinical deterioration
Reason for follow up CT could be: Clinical deterioration, Absence of or slow improvement, Routine follow­up
FollowUp.CTScannerType Original 16 == 16-slice
32 == 32-slice
64 == 64-slice
99 == Other
128 == 128-slice
256 == 256-slice
320 == 320-slice
Type of scanner used for follow up CT
FollowUp.CTSubduralHaematomaHygroma Original 0 == No
R == Right
L == Left
B == Bilateral
88 == Unknown
CT parameters scored by the investigator: reflects if there was subdural haematoma/hygroma on the Follow up CT and if yes, on which side.
FollowUp.CTType Original NCCT == Non-contrast CT
CCT == Contrast CT
CTA == CT Angiography
PCT == Perfusion CT
Type of CT scan for followup imaging
FollowUp.FUAttendance Original 0 == No attendance
1 == Subject
2 == Proxy (please specify)
3 == Health care professional taking care of patient
4 == N/A (death)
Documents who was present at the follow-up assessment. In case of postal Questionnaire, there would be "no attendance"
FollowUp.FUAttendanceProxyChild Original When a proxy was attending the Follow up visit, specification was needed whether this was: child, parent, partner, sibling or other caretaker. This variable reflects who often the proxy attending the follow up visit was the child of the patient.
FollowUp.FUAttendanceProxyOtherCaretaker Original When a proxy was attending the Follow up visit, specification was needed whether this was: child, parent, partner, sibling or other caretaker. This variable reflects who often the proxy attending the follow up visit was an other caretaker.
FollowUp.FUAttendanceProxyParent Original When a proxy was attending the Follow up visit, specification was needed whether this was: child, parent, partner, sibling or other caretaker. This variable reflects who often the proxy attending the follow up visit was a parent of the patient.
FollowUp.FUAttendanceProxyPartner Original When a proxy was attending the Follow up visit, specification was needed whether this was: child, parent, partner, sibling or other caretaker. This variable reflects who often the proxy attending the follow up visit was the partner of the patient.
FollowUp.FUAttendanceProxySibling Original When a proxy was attending the Follow up visit, specification was needed whether this was: child, parent, partner, sibling or other caretaker. This variable reflects who often the proxy attending the follow up visit was a sibling of the patient.
FollowUp.FUDisabilityDueToExtracranialInj Original 0 == No
1 == Mild/moderate
2 == Severe (requiring institutional care)
The variable is only valid when "FollowUp.FUVitStatus" is "alive". It reflects if the patient suffers from any disability due to an extracranial injury
FollowUp.FUImagingModality Original CT == CT
MRI == MRI
XRay == X-Ray Angiography
The variables concerning imaging modality, largely overlap with those with the in-hospital phase, however details of recording abnormalities and reasons for performing the imaging studies differ
FollowUp.FUIntracranialSurg Original 0 == No
1 == Yes
88 == Unknown
Reflects at the follow up visit if any intracranial surgery was performed after discharge
FollowUp.FUIntracranialSurgDate Original Date of the Intracranial surgery (after discharge) if performed Check also "FollowUp.FUIntracranialSurg".
FollowUp.FUIntracranialSurgOther Original If any form of intracranial surgery was performed after discharge (re-admission likely), this reflects if the type was other (than hydrocephalus, chronic subdural hematoma or cranioplasty)
FollowUp.FUIntracranialSurgSpecifyType Original 1 == Hydrocephalus
2 == Chronic subdural hematoma
3 == Cranioplasty
99 == Other
This variable aims to capture any form of intracranial surgery performed after discharge (re-admission likely)
FollowUp.FUIntracranialSurgTime Original Time of the Intracranial surgery (after discharge) if performed Check also "FollowUp.FUIntracranialSurg" and "FollowUp.FUIntracranialSurgDate"
FollowUp.FUMartlPartnerStatus Original 1 == Never been married
2 == Married
3 == Living together/common law
4 == Divorced
5 == Separated
6 == Widowed
88 == Unknown
99 == Other
Only recorded if change in SES; This variable needs to be related to the pre-injury situation: Subject.MartlPartnerStatus
FollowUp.FUMedAmantidine Original Only applicable if FollowUp.FUMedication = Yes. On Follow-up assessment, general information is captured on classes of medication taken and the reason for taking this.
FollowUp.FUMedAmantidineReason Original 1 == Agitation
2 == Attentional problems
3 == Behavioral disturbance
4 == Depression
5 == Memory difficulties
6 == Disorder of consciousness
7 == Fatigue
8 == Infection
9 == Pain - somatic
10 == Pain - neurogenic
11 == Pain - headache/migraine
12 == Paroxysmal sympathetic hyperactivity (PSH)
13 == Seizure - prophylaxis
14 == Seizure - treatment
15 == Spasticity
Only applicable if FollowUp.FUMedication = Yes. On Follow-up assessment, general information is captured on classes of medication taken and the reason for taking this.
FollowUp.FUMedAntibiotics Original Only applicable if FollowUp.FUMedication = Yes. On Follow-up assessment, general information is captured on classes of medication taken and the reason for taking this.
FollowUp.FUMedAntibioticsReason Original 1 == Agitation
2 == Attentional problems
3 == Behavioral disturbance
4 == Depression
5 == Memory difficulties
6 == Disorder of consciousness
7 == Fatigue
8 == Infection
9 == Pain - somatic
10 == Pain - neurogenic
11 == Pain - headache/migraine
12 == Paroxysmal sympathetic hyperactivity (PSH)
13 == Seizure - prophylaxis
14 == Seizure - treatment
15 == Spasticity
Only applicable if FollowUp.FUMedication = Yes. On Follow-up assessment, general information is captured on classes of medication taken and the reason for taking this.
FollowUp.FUMedAntiConv Original Only applicable if FollowUp.FUMedication = Yes. On Follow-up assessment, general information is captured on classes of medication taken and the reason for taking this.
FollowUp.FUMedAntiConvReason Original 1 == Agitation
2 == Attentional problems
3 == Behavioral disturbance
4 == Depression
5 == Memory difficulties
6 == Disorder of consciousness
7 == Fatigue
8 == Infection
9 == Pain - somatic
10 == Pain - neurogenic
11 == Pain - headache/migraine
12 == Paroxysmal sympathetic hyperactivity (PSH)
13 == Seizure - prophylaxis
14 == Seizure - treatment
15 == Spasticity
Only applicable if FollowUp.FUMedication = Yes. On Follow-up assessment, general information is captured on classes of medication taken and the reason for taking this.
FollowUp.FUMedAntidep Original Only applicable if FollowUp.FUMedication = Yes. On Follow-up assessment, general information is captured on classes of medication taken and the reason for taking this.
FollowUp.FUMedAntidepReason Original 1 == Agitation
2 == Attentional problems
3 == Behavioral disturbance
4 == Depression
5 == Memory difficulties
6 == Disorder of consciousness
7 == Fatigue
8 == Infection
9 == Pain - somatic
10 == Pain - neurogenic
11 == Pain - headache/migraine
12 == Paroxysmal sympathetic hyperactivity (PSH)
13 == Seizure - prophylaxis
14 == Seizure - treatment
15 == Spasticity
Only applicable if FollowUp.FUMedication = Yes. On Follow-up assessment, general information is captured on classes of medication taken and the reason for taking this.
FollowUp.FUMedAntipsycho Original Only applicable if FollowUp.FUMedication = Yes. On Follow-up assessment, general information is captured on classes of medication taken and the reason for taking this.
FollowUp.FUMedAntipsychoReason Original 1 == Agitation
2 == Attentional problems
3 == Behavioral disturbance
4 == Depression
5 == Memory difficulties
6 == Disorder of consciousness
7 == Fatigue
8 == Infection
9 == Pain - somatic
10 == Pain - neurogenic
11 == Pain - headache/migraine
12 == Paroxysmal sympathetic hyperactivity (PSH)
13 == Seizure - prophylaxis
14 == Seizure - treatment
15 == Spasticity
Only applicable if FollowUp.FUMedication = Yes. On Follow-up assessment, general information is captured on classes of medication taken and the reason for taking this.
FollowUp.FUMedAnxiolytics Original Only applicable if FollowUp.FUMedication = Yes. On Follow-up assessment, general information is captured on classes of medication taken and the reason for taking this.
FollowUp.FUMedAnxiolyticsReason Original 1 == Agitation
2 == Attentional problems
3 == Behavioral disturbance
4 == Depression
5 == Memory difficulties
6 == Disorder of consciousness
7 == Fatigue
8 == Infection
9 == Pain - somatic
10 == Pain - neurogenic
11 == Pain - headache/migraine
12 == Paroxysmal sympathetic hyperactivity (PSH)
13 == Seizure - prophylaxis
14 == Seizure - treatment
15 == Spasticity
Only applicable if FollowUp.FUMedication = Yes. On Follow-up assessment, general information is captured on classes of medication taken and the reason for taking this.
FollowUp.FUMedCholinergic Original Only applicable if FollowUp.FUMedication = Yes. On Follow-up assessment, general information is captured on classes of medication taken and the reason for taking this.
FollowUp.FUMedCholinergicReason Original 1 == Agitation
2 == Attentional problems
3 == Behavioral disturbance
4 == Depression
5 == Memory difficulties
6 == Disorder of consciousness
7 == Fatigue
8 == Infection
9 == Pain - somatic
10 == Pain - neurogenic
11 == Pain - headache/migraine
12 == Paroxysmal sympathetic hyperactivity (PSH)
13 == Seizure - prophylaxis
14 == Seizure - treatment
15 == Spasticity
Only applicable if FollowUp.FUMedication = Yes. On Follow-up assessment, general information is captured on classes of medication taken and the reason for taking this.
FollowUp.FUMedClonidine Original Only applicable if FollowUp.FUMedication = Yes. On Follow-up assessment, general information is captured on classes of medication taken and the reason for taking this.
FollowUp.FUMedClonidineReason Original 1 == Agitation
2 == Attentional problems
3 == Behavioral disturbance
4 == Depression
5 == Memory difficulties
6 == Disorder of consciousness
7 == Fatigue
8 == Infection
9 == Pain - somatic
10 == Pain - neurogenic
11 == Pain - headache/migraine
12 == Paroxysmal sympathetic hyperactivity (PSH)
13 == Seizure - prophylaxis
14 == Seizure - treatment
15 == Spasticity
Only applicable if FollowUp.FUMedication = Yes. On Follow-up assessment, general information is captured on classes of medication taken and the reason for taking this.
FollowUp.FUMedComplAutonomicInstability Original 0 == No
1 == Yes
88 == Unknown
On follow-up assessment, information is captured on medical complications and sequelae post-hospitalization. This reflects whether there has been Paroxysmal sympathetic hyperactivity (autonomic instability).
FollowUp.FUMedComplAutonomicInstabilityTreatment Original BPUMP == Baclofen pump
DRUGS == Drugs
On follow-up assessment, information is captured on medical complications and sequelae post-hospitalization. This reflects the treatment given in case there has been Paroxysmal sympathetic hyperactivity (autonomic instability.) See also "FollowUp.FUMedComplAutonomicInstability"
FollowUp.FUMedComplDVT Original 0 == No
1 == Yes
88 == Unknown
On follow-up assessment, information is captured on medical complications and sequelae post-hospitalization. This reflects whether there has been DVT (Deep venous thrombosis). Intent is to record here only DVT occurring post-discharge. DVT that occurred before/at presentation or during hospital stay is recorded elsewhere: Hospital.HospComplDVT
FollowUp.FUMedComplHeteroOss Original 0 == No
1 == Yes
88 == Unknown
On follow-up assessment, information is captured on medical complications and sequelae post-hospitalization. This reflects whether there has been Heterotopic ossification.
FollowUp.FUMedComplHeteroOssTreatment Original PLAN == Planned
PERF == Performed
On follow-up assessment, information is captured on medical complications and sequelae post-hospitalization. This reflects the treatment given in case there has been Heterotopic ossification. See also "FollowUp.FUMedComplHeteroOss".
FollowUp.FUMedComplPressureSores Original 0 == No
1 == Yes
88 == Unknown
On follow-up assessment, information is captured on medical complications and sequelae post-hospitalization. This reflects whether there has been Pressure sores.
FollowUp.FUMedComplPulmonaryEmbolus Original 0 == No
1 == Yes
88 == Unknown
On follow-up assessment, information is captured on medical complications and sequelae post-hospitalization. This reflects whether there has been Pulmonary embolism (PE) post-discharge. PE that occurred before/at presentation or during hospital stay is recorded elsewhere: Hospital.HospComplPumlEmb
FollowUp.FUMedComplSeizurePostDischarge Original 0 == No
1 == Yes
88 == Unknown
On follow-up assessment, information is captured on medical complications and sequelae post-hospitalization. This reflects whether there has been seizures occurring post-discharge. Seizures that occurred before/at presentation or during hospital stay are recorded elsewhere: InjuryHx.EDComplEventSeizures; Vitals.HosComplEventSeizures; Hospital.HospComplSeizures; Vitals.HosComplEventSeizures; Hospital.ICUDisComplSeizure; Outcomes.GOSEEpilepsyFits; Subjective reporting also in: Outcomes.PartQuestACurHltSeiz
FollowUp.FUMedComplSpasticity Original 0 == No
1 == Yes
88 == Unknown
On follow-up assessment, information is captured on medical complications and sequelae post-hospitalization. This reflects whether there has been spasticity.
FollowUp.FUMedComplSpasticityTreatment Original PHYS == Physiotherapy
IBAC == Intrathecal baclofen pump
OBAC == Oral baclofen
BENZ == Benzodiazepines
On follow-up assessment, information is captured on medical complications and sequelae post-hospitalization. This reflects the treatment given in case there has been spasticity.
FollowUp.FUMedication Original 0 == No
1 == Yes
88 == Unknown
On Follow-up assessment, general information is captured on classes of medication taken and the reason for taking this. No specific info on agent or dose is captured.
FollowUp.FUMedNarc Original Only applicable if FollowUp.FUMedication = Yes. On Follow-up assessment, general information is captured on classes of medication taken and the reason for taking this.
FollowUp.FUMedNarcReason Original 1 == Agitation
2 == Attentional problems
3 == Behavioral disturbance
4 == Depression
5 == Memory difficulties
6 == Disorder of consciousness
7 == Fatigue
8 == Infection
9 == Pain - somatic
10 == Pain - neurogenic
11 == Pain - headache/migraine
12 == Paroxysmal sympathetic hyperactivity (PSH)
13 == Seizure - prophylaxis
14 == Seizure - treatment
15 == Spasticity
Only applicable if FollowUp.FUMedication = Yes. On Follow-up assessment, general information is captured on classes of medication taken and the reason for taking this.
FollowUp.FUMedOther Original Only applicable if FollowUp.FUMedication = Yes. On Follow-up assessment, general information is captured on classes of medication taken and the reason for taking this.
FollowUp.FUMedOtherPain Original Only applicable if FollowUp.FUMedication = Yes. On Follow-up assessment, general information is captured on classes of medication taken and the reason for taking this.
FollowUp.FUMedOtherPainReason Original 1 == Agitation
2 == Attentional problems
3 == Behavioral disturbance
4 == Depression
5 == Memory difficulties
6 == Disorder of consciousness
7 == Fatigue
8 == Infection
9 == Pain - somatic
10 == Pain - neurogenic
11 == Pain - headache/migraine
12 == Paroxysmal sympathetic hyperactivity (PSH)
13 == Seizure - prophylaxis
14 == Seizure - treatment
15 == Spasticity
Only applicable if FollowUp.FUMedication = Yes. On Follow-up assessment, general information is captured on classes of medication taken and the reason for taking this.
FollowUp.FUMedOtherReason Original 1 == Agitation
2 == Attentional problems
3 == Behavioral disturbance
4 == Depression
5 == Memory difficulties
6 == Disorder of consciousness
7 == Fatigue
8 == Infection
9 == Pain - somatic
10 == Pain - neurogenic
11 == Pain - headache/migraine
12 == Paroxysmal sympathetic hyperactivity (PSH)
13 == Seizure - prophylaxis
14 == Seizure - treatment
15 == Spasticity
On Follow-up assessment, general information is captured on classes of medication taken and the reason for taking this. Only applicable if "FollowUp.FUMedication = Yes" and "FollowUp.FUMedOther" marked as valid.
FollowUp.FUMedOtherText Original Only applicable if FollowUp.FUMedication = Yes. On Follow-up assessment, general information is captured on classes of medication taken and the reason for taking this.
FollowUp.FUMedPsycho Original Only applicable if FollowUp.FUMedication = Yes. On Follow-up assessment, general information is captured on classes of medication taken and the reason for taking this.
FollowUp.FUMedPsychoReason Original 1 == Agitation
2 == Attentional problems
3 == Behavioral disturbance
4 == Depression
5 == Memory difficulties
6 == Disorder of consciousness
7 == Fatigue
8 == Infection
9 == Pain - somatic
10 == Pain - neurogenic
11 == Pain - headache/migraine
12 == Paroxysmal sympathetic hyperactivity (PSH)
13 == Seizure - prophylaxis
14 == Seizure - treatment
15 == Spasticity
Only applicable if FollowUp.FUMedication = Yes. On Follow-up assessment, general information is captured on classes of medication taken and the reason for taking this.
FollowUp.FUMedSteroids Original Only applicable if FollowUp.FUMedication = Yes. On Follow-up assessment, general information is captured on classes of medication taken and the reason for taking this.
FollowUp.FUMedSteroidsReason Original 1 == Agitation
2 == Attentional problems
3 == Behavioral disturbance
4 == Depression
5 == Memory difficulties
6 == Disorder of consciousness
7 == Fatigue
8 == Infection
9 == Pain - somatic
10 == Pain - neurogenic
11 == Pain - headache/migraine
12 == Paroxysmal sympathetic hyperactivity (PSH)
13 == Seizure - prophylaxis
14 == Seizure - treatment
15 == Spasticity
Only applicable if FollowUp.FUMedication = Yes. On Follow-up assessment, general information is captured on classes of medication taken and the reason for taking this.
FollowUp.FUPrincipalDeathCause Original 1 == Head injury/initial injury
2 == Head injury/secondary intracranial damage
3 == Systemic trauma
4 == Medical complications
88 == Unknown
99 == Other
On Follow-up assessment, information is captured whether the patience is still alive or not. This reflects the (post-hospitalization) death cause if the patient died post-discharge. Only applicable if FollowUp.FUVitStatus = Dead.
FollowUp.FUPrincipalDeathCauseOther Original On Follow-up assessment, information is captured whether the patience is still alive or not. This reflects the (post-hospitalization) death cause if the patient died post-discharge (if the cause was "other" than listed). Only applicable if FollowUp.FUVitStatus = Dead. See also "FollowUp.FUPrincipalDeathCause"
FollowUp.FUPtStillInICU Original This variable reflects if the patient was still in ICU at the time of a scheduled follow up visit.
FollowUp.FUReasonNoAttendance Original 1 == Not contactable
2 == Forgotten
3 == Refused
99 == Other
Documents reason if subject did not undergo Follow up assessment.
FollowUp.FURehabGenLongTermAcuteCUInPat Original Reflects the type of in-patient rehab care received: General long term acute care
FollowUp.FURehabGenRehabUnitInPat Original Reflects the type of in-patient rehab care received: General
FollowUp.FURehabGeriatricRehabUnitInPat Original Reflects the type of in-patient rehab care received: Geriatric
FollowUp.FURehabInPat Original Documents that patient received in-patient rehab care at the time of this assessment.
FollowUp.FURehabInPatAdmisDate Original Date of admission for the in-patient rehab care.
FollowUp.FURehabInPatDischDate Original Date of discharge for the in-patient rehab care.
FollowUp.FURehabInPatOngoingRehab Original 0 == No
1 == Yes
Reflects if the in-patient rehab was still ongoing at the time of the follow up assessment.
FollowUp.FURehabInPatShortTermInterrup1EndDate Original Only applicable in case the inpatient rehab was interrupted for specific reasons
FollowUp.FURehabInPatShortTermInterrup1StartDate Original Only applicable in case the inpatient rehab was interrupted for specific reasons
FollowUp.FURehabInPatShortTermInterrup2EndDate Original Only applicable in case the inpatient rehab was interrupted for specific reasons
FollowUp.FURehabInPatShortTermInterrup2StartDate Original Only applicable in case the inpatient rehab was interrupted for specific reasons
FollowUp.FURehabInPatShortTermInterrup3EndDate Original Only applicable in case the inpatient rehab was interrupted for specific reasons
FollowUp.FURehabInPatShortTermInterrup3StartDate Original Only applicable in case the inpatient rehab was interrupted for specific reasons
FollowUp.FURehabNo Original Documents that patient received no rehab at the time of this assessment.
FollowUp.FURehabOutPat Original Documents that patient received out-patient rehab care at the time of this assessment.
FollowUp.FURehabOutPatAdmisDate Original Start Date of the out-patient rehab care.
FollowUp.FURehabOutPatTherpyCog Original Reflects the type of out-patient rehab care received: Cognitive remediation
FollowUp.FURehabOutPatTherpyCogFreq Original 1 == 1 - None
2 == 2 - Only follow-up, no active treatment
3 == 3 - < Once a week
4 == 4 - Weekly
5 == 5 - 2-3 times/week
6 == 6 - Daily
7 == 7 - Unknown
Reflects the frequency of Cognitive remediation received as out-patient rehab care. Check also "FollowUp.FURehabOutPatTherpyCog".
FollowUp.FURehabOutPatTherpyCompDayTreatmnt Original Reflects the type of out-patient rehab care received: Comprehensive day treatment
FollowUp.FURehabOutPatTherpyCompDayTreatmntFreq Original 1 == 1 - None
2 == 2 - Only follow-up, no active treatment
3 == 3 - < Once a week
4 == 4 - Weekly
5 == 5 - 2-3 times/week
6 == 6 - Daily
7 == 7 - Unknown
Reflects the frequency of Comprehensive day treatment received as out-patient rehab care. Check also "FollowUp.FURehabOutPatTherpyCompDayTreatmnt"
FollowUp.FURehabOutPatTherpyHomeHealth Original Reflects the type of out-patient rehab care received: Home health
FollowUp.FURehabOutPatTherpyHomeHealthFreq Original 1 == 1 - None
2 == 2 - Only follow-up, no active treatment
3 == 3 - < Once a week
4 == 4 - Weekly
5 == 5 - 2-3 times/week
6 == 6 - Daily
7 == 7 - Unknown
Reflects the frequency of 'Home health' received as out-patient rehab care. Check also "FollowUp.FURehabOutPatTherpyHomeHealth"
FollowUp.FURehabOutPatTherpyIndLivngTrainng Original Reflects the type of out-patient rehab care received: Independent living training
FollowUp.FURehabOutPatTherpyIndLivngTrainngFreq Original 1 == 1 - None
2 == 2 - Only follow-up, no active treatment
3 == 3 - < Once a week
4 == 4 - Weekly
5 == 5 - 2-3 times/week
6 == 6 - Daily
7 == 7 - Unknown
Reflects the frequency of 'Independent living training' received as out-patient rehab care. Check also "FollowUp.FURehabOutPatTherpyIndLivngTrainng"
FollowUp.FURehabOutPatTherpyNursServ Original Reflects the type of out-patient rehab care received: Nursing services
FollowUp.FURehabOutPatTherpyNursServFreq Original 1 == 1 - None
2 == 2 - Only follow-up, no active treatment
3 == 3 - < Once a week
4 == 4 - Weekly
5 == 5 - 2-3 times/week
6 == 6 - Daily
7 == 7 - Unknown
Reflects the frequency of 'Nursing services' received as out-patient rehab care. Check also "FollowUp.FURehabOutPatTherpyNursServ"
FollowUp.FURehabOutPatTherpyOcc Original Reflects the type of out-patient rehab care received: Occupational therapy
FollowUp.FURehabOutPatTherpyOccFreq Original 1 == 1 - None
2 == 2 - Only follow-up, no active treatment
3 == 3 - < Once a week
4 == 4 - Weekly
5 == 5 - 2-3 times/week
6 == 6 - Daily
7 == 7 - Unknown
Reflects the frequency of 'Occupational therapy' received as out-patient rehab care. Check also "FollowUp.FURehabOutPatTherpyOcc"
FollowUp.FURehabOutPatTherpyOther Original Reflects the type of out-patient rehab care received: "Other" than the listed types Check also "FollowUp.FURehabOutPatTherpyOtherText" for the specification on the type of "other".
FollowUp.FURehabOutPatTherpyOtherFreq Original 1 == 1 - None
2 == 2 - Only follow-up, no active treatment
3 == 3 - < Once a week
4 == 4 - Weekly
5 == 5 - 2-3 times/week
6 == 6 - Daily
7 == 7 - Unknown
Reflects the frequency of "Other" therapy received as out-patient rehab care.
FollowUp.FURehabOutPatTherpyOtherText Original Specifies the type of "other" out-patient rehab care received. Check also "FollowUp.FURehabOutPatTherpyOther"
FollowUp.FURehabOutPatTherpyPeerMentor Original Reflects the type of out-patient rehab care received: Peer mentoring
FollowUp.FURehabOutPatTherpyPeerMentorFreq Original 1 == 1 - None
2 == 2 - Only follow-up, no active treatment
3 == 3 - < Once a week
4 == 4 - Weekly
5 == 5 - 2-3 times/week
6 == 6 - Daily
7 == 7 - Unknown
Reflects the frequency of 'Peer mentoring' received as out-patient rehab care. Check also "FollowUp.FURehabOutPatTherpyPeerMentor"
FollowUp.FURehabOutPatTherpyPhysicianInvolved Original 0 == No
1 == Yes
88 == Unknown
Reflects if a Rehab physician was involved, in case the patient received out-patient rehab care.
FollowUp.FURehabOutPatTherpyPsychSer Original Reflects the type of out-patient rehab care received: Psychological services
FollowUp.FURehabOutPatTherpyPsychSerFreq Original 1 == 1 - None
2 == 2 - Only follow-up, no active treatment
3 == 3 - < Once a week
4 == 4 - Weekly
5 == 5 - 2-3 times/week
6 == 6 - Daily
7 == 7 - Unknown
Reflects the frequency of 'Psychological services' received as out-patient rehab care. Check also "FollowUp.FURehabOutPatTherpyPsychSer"
FollowUp.FURehabOutPatTherpyPT Original Reflects the type of out-patient rehab care received: Physical therapy
FollowUp.FURehabOutPatTherpyPTFreq Original 1 == 1 - None
2 == 2 - Only follow-up, no active treatment
3 == 3 - < Once a week
4 == 4 - Weekly
5 == 5 - 2-3 times/week
6 == 6 - Daily
7 == 7 - Unknown
Reflects the frequency of 'Physical therapy' received as out-patient rehab care. Check also "FollowUp.FURehabOutPatTherpyPT"
FollowUp.FURehabOutPatTherpyRec Original Reflects the type of out-patient rehab care received: Therapeutic recreaction
FollowUp.FURehabOutPatTherpyRecFreq Original 1 == 1 - None
2 == 2 - Only follow-up, no active treatment
3 == 3 - < Once a week
4 == 4 - Weekly
5 == 5 - 2-3 times/week
6 == 6 - Daily
7 == 7 - Unknown
Reflects the frequency of "Therapeutic recreaction" received as out-patient rehab care. Check also "FollowUp.FURehabOutPatTherpyRec"
FollowUp.FURehabOutPatTherpySocWrkCaseMgmt Original Reflects the type of out-patient rehab care received: Social work/Case management
FollowUp.FURehabOutPatTherpySocWrkCaseMgmtFreq Original 1 == 1 - None
2 == 2 - Only follow-up, no active treatment
3 == 3 - < Once a week
4 == 4 - Weekly
5 == 5 - 2-3 times/week
6 == 6 - Daily
7 == 7 - Unknown
Reflects the frequency of 'Social work/Case management' received as out-patient rehab care. Check also "FollowUp.FURehabOutPatTherpySocWrkCaseMgmt"
FollowUp.FURehabOutPatTherpySpeech Original Reflects the type of out-patient rehab care received: Speech therapy
FollowUp.FURehabOutPatTherpySpeechFreq Original 1 == 1 - None
2 == 2 - Only follow-up, no active treatment
3 == 3 - < Once a week
4 == 4 - Weekly
5 == 5 - 2-3 times/week
6 == 6 - Daily
7 == 7 - Unknown
Reflects the frequency of 'Speech therapy' received as out-patient rehab care. Check also "FollowUp.FURehabOutPatTherpySpeech"
FollowUp.FURehabOutPatTherpyStructure Original 1 == Mono-disciplinary (little/nocollaboration between care providers
2 == Multi-disciplinary
Reflects the structure of the out-patient rehab care received.
FollowUp.FURehabOutPatTherpyUnknown Original Reflects if out-patient rehab care was received but the type was "Unknown"
FollowUp.FURehabOutPatTherpyUnknownFreq Original 1 == 1 - None
2 == 2 - Only follow-up, no active treatment
3 == 3 - < Once a week
4 == 4 - Weekly
5 == 5 - 2-3 times/week
6 == 6 - Daily
7 == 7 - Unknown
Reflects the frequency of "Unknown" therapy received as out-patient rehab care. Check also "FollowUp.FURehabOutPatTherpyUnknown"
FollowUp.FURehabOutPatTherpyVocServ Original Reflects the type of out-patient rehab care received: Vocational services
FollowUp.FURehabOutPatTherpyVocServFreq Original 1 == 1 - None
2 == 2 - Only follow-up, no active treatment
3 == 3 - < Once a week
4 == 4 - Weekly
5 == 5 - 2-3 times/week
6 == 6 - Daily
7 == 7 - Unknown
Reflects the frequency of "Vocational services" received as out-patient rehab care. Check also "FollowUp.FURehabOutPatTherpyVocServ"
FollowUp.FURehabTBIRehabUnitInPat Original Reflects the type of in-patient rehab care received: TBI
FollowUp.FURehabTherpyEndDate Original End date of the out-patient rehab care.
FollowUp.FURehabTherpyOngoingInd Original 0 == No
1 == Yes
Reflects if the out-patient rehab care was still ongoing at the time of the follow up assessment.
FollowUp.FURehabUnknown Original Reflects if it was "unknown" whether rehab treatment had occurred at the time of this assessment.
FollowUp.FUResdncType Original 1 == Living at home independently
2 == Living at home supported by family/carers
6 == Living in a long-stay patient ward(hospital)
7 == Rehabilitation centre
10 == Living in nursing home
11 == Living in shelteed + housing/community care
99 == Other
Only recorded if change in SES. Reflects the Living situation/patient's residence at the time of follow up assessment, if there was a change in SES.
FollowUp.FUResdncTypeOther Original Only recorded if change in SES Specifies the "Other" Living situation/patient's residence at the time of follow up assessment, if there was a change in SES.
FollowUp.FURtrnToOtherAct Original 0 == No
1 == Full return to previous level
2 == Reduced level
88 == Unknown
Prefects if at the time of follow up assessment the patient returned to other activities than work/school and at what level.
FollowUp.FURtrnWrkSchlStatus Original NA == N/A
1 == Returned to previous job / school at same level and hours
2 == Unable to work / go to school
5 == Looking for work / go to school
7 == Retired
8 == Returned to previous job / school at increased levels or hours from pre-injury
9 == Returned to previous job / school at reduced level or hours
10 == Change of job / different work or school
11 == Special employment / sheltered employment
88 == Unknown
Prefects if at the time of follow up assessment the patient returned to work/school and at what level.
FollowUp.FUSESChange Original 0 == No
1 == Yes
88 == Unknown
This variable aims to document any change in socio-economic status following the TBI
FollowUp.FUSESPeopleLivingWith Original Only recorded if change in SES Reflects the "Number of people living with" at the time of follow up assessment, if there was a change in SES.
FollowUp.FUSESPrimAdultAlone Original Only recorded if change in SES Reflects the "Persons living with" at the time of follow up assessment, if there was a change in SES: Alone
FollowUp.FUSESPrimAdultCarerUnrelated Original Only recorded if change in SES Reflects the "Persons living with" at the time of follow up assessment, if there was a change in SES: Carers unrelated to patient
FollowUp.FUSESPrimAdultChildren Original Only recorded if change in SES Reflects the "Persons living with" at the time of follow up assessment, if there was a change in SES: Child/children
FollowUp.FUSESPrimAdultOther Original Only recorded if change in SES Reflects the "Persons living with" at the time of follow up assessment, if there was a change in SES: Other (incl. correctional facility inmates)
FollowUp.FUSESPrimAdultParents Original Only recorded if change in SES Reflects the "Persons living with" at the time of follow up assessment, if there was a change in SES: Parents
FollowUp.FUSESPrimAdultSiblings Original Only recorded if change in SES Reflects the "Persons living with" at the time of follow up assessment, if there was a change in SES: Siblings
FollowUp.FUSESPrimAdultSignOther Original Only recorded if change in SES Reflects the "Persons living with" at the time of follow up assessment, if there was a change in SES: Significant other partner
FollowUp.FUSESPrimAdultSpousePartner Original Only recorded if change in SES Reflects the "Persons living with" at the time of follow up assessment, if there was a change in SES: Spouse (including common law partner)
FollowUp.FUSESPrimAdultUnknown Original Only recorded if change in SES Reflects the "Persons living with" at the time of follow up assessment, if there was a change in SES: Unknown
FollowUp.FUSurgCranioplastyPerformed Original 0 == No
1 == Yes
2 == No, but scheduled
On Follow-up assessment, general information is captured on Medical and Surgical Therapies. This reflects if Cranioplasty was performed. Only applicable in case a decompressive craniectomy was performed during the in-hospital period
FollowUp.FUSurgExtracranialSurg Original 0 == No
1 == Yes
88 == Unknown
On Follow-up assessment, general information is captured on Medical and Surgical Therapies. This variable aims to capture any form of extracranial surgery performed after discharge
FollowUp.FUSurgExtracranialSurgDate Original On Follow-up assessment, general information is captured on Medical and Surgical Therapies. This variable reflects the date, in case any form of extracranial surgery was performed.
FollowUp.FUSurgExtracranialSurgSpecify Original On Follow-up assessment, general information is captured on Medical and Surgical Therapies. This variable specifies the type, in case any form of extracranial surgery was performed.
FollowUp.FUSurgExtracranialSurgTime Original On Follow-up assessment, general information is captured on Medical and Surgical Therapies. This variable reflects the date, in case any form of extracranial surgery was performed.
FollowUp.FUVisitDate Original Date of follow up visit
FollowUp.FUVisitTime Original Time of follow up visit. Check also "FollowUp.FUVisitDate" for the date.
FollowUp.FUVisitType Original SCHED == Scheduled study follow-up
UNSCHED == Unscheduled follow-up
All Follow-up assessments used questionnaire assessments, and at selected pre-specified time points, neuropsychological testing was done during out-patient follow-up. The schedule for assessments was differentiated by stratum. Cross-sectional assessments, including questionnaires and neuropsych, was performed at 6 mnths post injury. Further Questionnaire assessments were schduled as follows: ER stratum: 2-3 weeks and 3 months; Adm stratum: 3 mnths and 12 mnths; ICU stratum: 3 months and 12 months.
FollowUp.FUVitStatus Original 0 == Dead
1 == Alive
88 == Unknown
This variable reflects the status of the patient at the time of a scheduled follow up visit. The status could be Dead, Alive, Unknown
FollowUp.IcometrixImageId Original Identifier generated for an imaging experiment when images are uploaded from site It's recommended to use: Imaging.CRFIcometrixImageId
FollowUp.IcometrixPassedQA Original 0 == No
1 == Yes
Reflects if images uploaded from site passed QA of icometix. It's recommended to use: Imaging.CRFIcometrixPassedQA
FollowUp.IcometrixQADateTime Original Date and time when central QA was done for followup images It's recommended to use: Imaging.CRFIcometrixQADateTime
FollowUp.IcometrixUploadDateTime Original Date/Time of image upload to Icometrix
FollowUp.InitialDataIcometrix Original Reflects if the imaging data was not entered by the site in the e-CRF but directly from the images at icometrix (if not, it means the data in the e-CRF was entered manually by the study nurse) It's recommended to use "Imaging.CRFInitialDataIcometrix"
FollowUp.MRIManuf Original SIEM == Siemens
PHIL == Philips
GE == GE
TOSH == Toshiba
99 == Other
This variable reflects the manufacturer of the follow up MRI scanner used. It's recommended to use "Imaging.CRFMRIManuf"
FollowUp.MRIReason Original CR == Clinical routine
ISC == Ischemia
SBL == Suspicious brainstem lesions
LOP == Lack of improvement
CD == Clinical deterioration
SP == Study protocol
88 == Unknown
99 == Other
This variable contains the main reason why an MRI at follow up was performed. It's recommended to use Imaging.CRFMRIReason
FollowUp.MRIReasonOther Original Specifies the type of "other" reason for MRI at follow up It's recommended to use Imaging.CRFMRIReasonOther
FollowUp.MRIResultPreExistAbnorm Original 0 == No
1 == Yes
88 == Unknown
Scored by investigator Reflects if there are pre-existing abnormalities on the follow up MRI. It’s recommended to use Imaging.CRFMRIResultPreExistAbnorm
FollowUp.MRIResultTraumaticAbnorm Original 0 == No
1 == Yes
88 == Unknown
Scored by investigator Reflects if there are Traumatic abnormalities on the follow up MRI. It’s recommended to use Imaging.CRFMRIResultTraumaticAbnorm
FollowUp.MRIScannerStrength Original This variable describes the follow up MRI scanner strength. This is a text field. It’s recommended to use Imaging.CRFMRIScannerStrength
FollowUp.MRISequences Original T1 == T1
T2 == T2
DWI == DWI
FLAIR == FLAIR
GRE == GRE
DTI == DTI
SWI == SWI
MRSI == MRSI
PWI == PWI
99 == Other
This variable describes the follow up MRI sequence. Options are: T1, T2, FLAIR, DWI, GRE, SWI, DTI, MRSI, PWI, Other. Multiple options can be selected. It’s recommended to use Imaging.CRFMRISequences
FollowUp.MRITraumAbnormASDH Original 0 == No
1 == Yes
88 == Unknown
This variable describes whether or not there is an acute subdural hematoma present on follow up MRI scan (yes, no, unknown). Assessment by investigator and/or physician. It’s recommended to use Imaging.CRFMRITraumAbnormASDH
FollowUp.MRITraumAbnormContusion Original 0 == No
1 == Yes
88 == Unknown
This variable describes whether or not there is a contusion present on MRI scan (yes, no, unknown). Assessment by investigator and/or physician. It’s recommended to use Imaging.CRFMRITraumAbnormContusion
FollowUp.MRITraumAbnormDAI Original 0 == No
1 == Yes
88 == Unknown
This variable describes whether or not there is DAI (diffuse axonal injury) present on MRI scan (yes, no, unknown). Assessment by investigator and/or physician. It’s recommended to use Imaging.CRFMRITraumAbnormDAI
FollowUp.MRITraumAbnormDAILesionLocBrainstem Original 0 == No
1 == Yes
88 == Unknown
This variable describes whether or not there is a brain stem lesion present on follow up MRI scan (yes, no, unknown). Assessment by investigator and/or physician. It’s recommended to use Imaging.CRFMRITraumAbnormDAILesionLocBrainstem
FollowUp.MRITraumAbnormDAILesionLocCorpusCallosum Original 0 == No
1 == Yes
88 == Unknown
This variable describes whether or not there is a corpus callosum lesion present on follow up MRI scan (yes, no, unknown). Assessment by investigator and/or physician. It’s recommended to use Imaging.CRFMRITraumAbnormDAILesionLocCorpusCallosum
FollowUp.MRITraumAbnormDAILesionLocDiffuseWhiteMatter Original 0 == No
1 == Yes
88 == Unknown
This variable describes whether or not there is a lesion in diffuse white matter present on follow up MRI scan (yes, no, unknown). Assessment by investigator and/or physician. It’s recommended to use Imaging.CRFMRITraumAbnormDAILesionLocDiffuseWhiteMatter
FollowUp.MRITraumAbnormDAINumLesions Original 1 == 1
2 == 2
3 == 3
4 == 4
5 == >= 5
This variable describes how many DAI lesions are present on follow up MRI scan (1,2,3,4,>=5). Assessment by investigator and/or physician. It’s recommended to use Imaging.CRFMRITraumAbnormDAINumLesions
FollowUp.MRITraumAbnormEDH Original 0 == No
1 == Yes
88 == Unknown
This variable describes whether or not there is an epidural hematoma present on follow up MRI scan (yes, no, unknown). Assessment by investigator and/or physician. It’s recommended to use Imaging.CRFMRITraumAbnormEDH
FollowUp.MRIType Original MRI == MRI
MRA == MRA
This variable describes the type of follow up MRI scan that has been made. Options are: MRI, MRA It’s recommended to use Imaging.CRFMRIType
FollowUp.TimePoint Original 2wk == 2 weeks
3mo == 3 months
6mo == 6 months
12mo == 12 months
24mo == 24 months
Follow up timepoints are 2-3 weeks, 3 months, 6 months, 12 months and 24 months. Depending on the stratum and sub-studies of a patient, follow up was performed at some of these time points or at all timepoints. For an overview, please check the SOP Manual.
Genetics.CollectionDate Meta Collection Date and Time of the Genetic sample. These date/time values were provided by the sites on the “sample collection and processing forms” enclosed to the samples.
Genetics.CollectionTime Meta Collection Date and Time of the Genetic sample. These date/time values were provided by the sites on the “sample collection and processing forms” enclosed to the samples.
Genetics.FreezerMinusEightyDate Meta The 4.9ml whole blood sample for genetic assays should be stored at -80°C with a needle to freezer time preferably within 6 hours. This variable reflects the date and time that the sample was stored in a minus 80 freezer. These date/time values were provided by the sites on the “sample collection and processing forms” enclosed to the samples.
Genetics.FreezerMinusEightyTime Meta The 4.9ml whole blood sample for genetic assays should be stored at -80°C with a needle to freezer time preferably within 6 hours. This variable reflects the date and time that the sample was stored in a minus 80 freezer. These date/time values were provided by the sites on the “sample collection and processing forms” enclosed to the samples.
Genetics.FreezerMinusTwentyDate Meta The 4.9ml whole blood sample for genetic assays should be stored at -80°C with a needle to freezer time preferably within 6 hours. However, if a -80°C freezer was not immediately accessible, samples could be temporarely (max 48 hours) stored in a minus 20°C non-frost-free freezer. This variable reflects the date and time that the sample was stored in a minus 20 freezer. These date/time values were provided by the sites on the “sample collection and processing forms” enclosed to the samples.
Genetics.FreezerMinusTwentyTime Meta The 4.9ml whole blood sample for genetic assays should be stored at -80°C with a needle to freezer time preferably within 6 hours. However, if a -80°C freezer was not immediately accessible, samples could be temporarely (max 48 hours) stored in a minus 20°C non-frost-free freezer. This variable reflects the date and time that the sample was stored in a minus 20 freezer. These date/time values were provided by the sites on the “sample collection and processing forms” enclosed to the samples.
Genetics.SampleId Meta Per patient 1x 4.9 ml blood samples was collected into 1x 4.9 ml potassium EDTA tubes for genetic assays.
Hospital.AdditionalStudiesCoag Original 0 == No
1 == Yes
Intended to provide documentation if the patient was enrolled in the Coagulation sub-study or not.
Hospital.AdditionalStudiesECoG Original 0 == No
1 == Yes
Intended to provide documentation if the patient was enrolled in the ECoG sub-study or not.
Hospital.AdditionalStudiesEEG Original 0 == No
1 == Yes
Intended to provide documentation if the patient was enrolled in the EEG sub-study or not.
Hospital.AdditionalStudiesTEGRotem Original 0 == No
1 == Yes
Intended to provide documentation if the patient was enrolled in the TEG/ROTEM sub-study or not.
Hospital.BrainDeathDate Original Reflects the date of Brain death in case of Withdrawal of life-sustaining measures
Hospital.BrainDeathTime Original Reflects the Time of Brain death in case of Withdrawal of life-sustaining measures Check also "Hospital.BrainDeathDate" for the date.
Hospital.ComplCRBSIDateDiagnosis Original At discharge, complications and adverse events were summarized. This variable reflects the date of diagnosis of CRBSI in case of systemic complication.
Hospital.DeadAge Original 0 == No
1 == Yes
88 == Unknown
Reflects if the reason for Withdrawal of life-sustaining measures was age.
Hospital.DeadCoMorbidities Original 0 == No
1 == Yes
88 == Unknown
Reflects if the reason for Withdrawal of life-sustaining measures was co-morbidities.
Hospital.DeadDeterminationOfBrainDeath Original 0 == No
1 == Yes
88 == Unknown
Reflects if the reason for Withdrawal of life-sustaining measures was Determination of brain death (according to national law).
Hospital.DeadOrganDonation Original 0 == No
1 == Yes
88 == Unknown
Reflects if Withdrawal of life-sustaining measures was followed by organ donation.
Hospital.DeadPatWill Original 0 == No
1 == Yes
88 == Unknown
Reflects if the reason for Withdrawal of life-sustaining measures was Following living will of patient.
Hospital.DeadRequestRelatives Original 0 == No
1 == Yes
88 == Unknown
Reflects if the reason for Withdrawal of life-sustaining measures was On request of relatives.
Hospital.DeadSeverityofTBI Original 0 == No
1 == Yes
88 == Unknown
Reflects if the reason for Withdrawal of life-sustaining measures was Severity of TBI.
Hospital.DeathAutopsy Original 0 == No
1 == Yes, forensic
2 == Yes, clinical
88 == Unknown
Reflects if an autopsy was performed after the death of the patient.
Hospital.DeathCause Original 1 == Head injury/initial injury
2 == Head injury/secondary intracranial damage
3 == Systemic trauma
4 == Medical complications
99 == Other
Reflects the principal cause of death of a patient in-hospital.
Hospital.DeathCauseOther Original Reflects if the cause of in-hospital death was "other" than the listed causes.
Hospital.DischargeStatus Original 0 == Dead
1 == Alive
88 == Unknown
Assessment by investigator Reflects if the patient was dead or alive at discharge.
Hospital.DispHosp Original 1 == Other hospital
2 == Rehab unit
3 == Nursing home
5 == Home
88 == Unknown
99 == Other
Documents destination upon hospital discharge
Hospital.DispHospOther Original Specifies if the reason for hospital discharge was "other" than the listed discharge reasons.
Hospital.GCSHospDischargeEyes Original UN == Unknown
S == Untestable (swollen)
O == Untestable (other)
1 == 1-None
2 == 2-To pain
3 == 3-To speech
4 == 4-Spontaneously
Eye opening score for GCS at hospital discharge.
Hospital.GCSHospDischargeMotor Original UN == Unknown
O == Untestable (Other)
P == Untestable (Deep sedation/paralyzed)
1 == 1-None
2 == 2-Abnormal extension
3 == 3-Abnormal flexion
4 == 4-Normal flexion/withdrawal
5 == 5-Localizes to pain
6 == 6-Obeys command
Motor score for GCS at hospital discharge.
Hospital.GCSHospDischargeScore Original GCS score at hospital discharge.
Hospital.GCSHospDischargeVerbal Original UN == Unknown
T == Untestable (tracheotomy/endotracheal tube)
O == Untestable (Other)
1 == 1-None
2 == 2-Incomprehensible sound
3 == 3-Inappropriate words
4 == 4-Confused
5 == 5-Oriented
Verbal score for GCS at hospital discharge.
Hospital.HospComplCardio Original 0 == No
1 == Yes
At discharge, complications and adverse events were summarized. This variable reflects the presence or absence of Cardiovascular as systemic complications.
Hospital.HospComplCRBSI Original 0 == No
1 == Yes
At discharge, complications and adverse events were summarized. This variable reflects the presence or absence of CRBSI (catheter related blood stream infection) as systemic complications.
Hospital.HospComplDelayedHaema Original 0 == No
1 == Yes
At discharge, complications and adverse events were summarized. This variable reflects the presence or absence of Delayed haematoma as Intracranial complications (requiring treatment).
Hospital.HospComplDVT Original 0 == No
1 == Yes
At discharge, complications and adverse events were summarized. This variable reflects the presence or absence of DVT (deep venous thrombosis) as systemic complications.
Hospital.HospComplIntraCranOther Original 0 == No
1 == Yes
At discharge, complications and adverse events were summarized. This variable reflects the presence or absence of "Other" Intracranial complications (requiring treatment) than listed.
Hospital.HospComplIntraCranOtherTxt Original At discharge, complications and adverse events were summarized. This variable reflects the type of "Other" Intracranial complications (requiring treatment).
Hospital.HospComplMeningitis Original 0 == No
1 == Yes
At discharge, complications and adverse events were summarized. This variable reflects the presence or absence of Meningitis/Ventriculitis as Intracranial complications (requiring treatment).
Hospital.HospComplMetabolic Original 0 == No
1 == Yes
At discharge, complications and adverse events were summarized. This variable reflects the presence or absence of Metabolic as systemic complications.
Hospital.HospComplPressureSore Original 0 == No
1 == Yes
At discharge, complications and adverse events were summarized. This variable reflects the presence or absence of Pressures sores (decubitus) as systemic complications.
Hospital.HospComplPumlEmb Original 0 == No
1 == Yes
At discharge, complications and adverse events were summarized. This variable reflects the presence or absence of Pulmonary embolus as systemic complications.
Hospital.HospComplRasiedICP Original 0 == No
1 == Yes
At discharge, complications and adverse events were summarized. This variable reflects the presence or absence of Raised ICP as Intracranial complications (requiring treatment).
Hospital.HospComplResp Original 0 == No
1 == Yes
At discharge, complications and adverse events were summarized. This variable reflects the presence or absence of Respiratory as systemic complications.
Hospital.HospComplSeizures Original 0 == No
1 == Yes
At discharge, complications and adverse events were summarized. This variable reflects the presence or absence of Seizures as Intracranial complications (requiring treatment).
Hospital.HospComplSystemOther Original 0 == No
1 == Yes
At discharge, complications and adverse events were summarized. This variable reflects the presence or absence of "Other" systemic complications than listed.
Hospital.HospComplSystemOtherTxt Original At discharge, complications and adverse events were summarized. This variable reflects the type of "Other" systemic complications.
Hospital.HospComplUTI Original 0 == No
1 == Yes
At discharge, complications and adverse events were summarized. This variable reflects the presence or absence of Urinary tract infection as systemic complications.
Hospital.HospDischargeBodyWeightkg Original Body weight on discharge in Kgs
Hospital.HospDischargeBodyWeightlbs Original Body weight on discharge in Lbs
Hospital.HospDischargeBodyWeightMeasure Original 1 == Estimated
2 == Measured
Reflects if Body weight was measured at discharge
Hospital.HospDischargeBodyWeightUnit Original 1 == kgs
2 == lbs
Reflects the unit used for body weight at discharge (kgs or lbs).
Hospital.HospDischargeCTProgression Original 0 == No
1 == Yes
Pre-defined early endpoints recorded at ICU or hospital discharge include: neuroworsening (any episode), time to obeying commands, duration of PTA, number of CTs performed and CT progression.
Hospital.HospDischargeCTProgressionYes Original 1 == Increase in initial lesion
2 == Development of new lesion
Pre-defined early endpoints recorded at ICU discharge or hospital discharge include: neuroworsening (any episode), time to obeying commands, duration of PTA, number of CTs performed and CT progression. If CT progression was "yes", this reflects if there was Increase in initial lesion or Development of new lesion.
Hospital.HospDischargeNumberCT Original 0 == No
1 == Yes
Pre-defined early endpoints recorded at ICU or hospital discharge include: neuroworsening (any episode), time to obeying commands, duration of PTA, number of CTs performed and CT progression.
Hospital.HospDischargeReason Original 0 == No institutional care necessary
1 == No institutional care in trauma center necessary
2 == Clinical rehab required but not approved
3 == Waiting list for rehab
4 == Clinical rehab required and approved
5 == No benefit of clinical rehab anticipated
99 == Other
WHY question: documents reason for choice of (hospital) discharge destination.
Hospital.HospDischargeReasonOther Original Specifies if the reason for (hospital) discharge destination was "other".
Hospital.HospDischargeTimeToObeyCommands Original Pre-defined early endpoints recorded at ICU or hospital discharge include: neuroworsening (any episode), time to obeying commands, duration of PTA, number of CTs performed and CT progression.
Hospital.HospDischargeTimeToObeyCommandsNotApplic Original Intended for use in patients who did not improve to obeying commands at the time of discharge. However, some sites may have used this to mark also patients who never had a depression of consciousness, to the extend that they did not obey commands.
Hospital.HospDischDate Original Hospital discharge:this variable was included also in the ICU form, in particular to record discharge dates for patients discharged directly from the ICU either dead or alive.
Hospital.HospDischPTADays Original This variable aims to facilitate collection of more information on PTA for subjects who were still in PTA at the time of admission to hospital. For study-broad interpretation of PTA,, the PTA as recorded on discharge from ER should also be taken into consideration: InjuryHx.LOCPTADuration
Hospital.HospDischPTADaysNA Original This variable could have been interpreted as either patients never having had PTA or alternatively, a patient who did not recover out of PTA by the time of discharge.
Hospital.HospDischPTAOngoing Original Intended to designate patients who are still in PTA at the moment of discharge of hospital
Hospital.HospDischTime Original Hospital discharge:this variable was included also in the ICU form, in particular to record discharge dates for patients discharged directly from the ICU either dead or alive.
Hospital.HospNeuroworseEpisode Original 0 == No
1 == Yes
Pre-defined early endpoints recorded at ICU or hospital discharge include: neuroworsening (any episode), time to obeying commands, duration of PTA, number of CTs performed and CT progression.
Hospital.ICDCode1 Original Up to 16 fields available to enter diagnosis as recorded by hospital administration according to ICD codes; applicable to patients admitted/discharged from hospital. For patients discharged directly from the ER, ICD codes are documented in: InjuryHx.ERDestICDCodes1
Hospital.ICDCode10 Original Up to 16 fields available to enter diagnosis as recorded by hospital administration according to ICD codes; applicable to patients admitted/discharged from hospital. For patients discharged directly from the ER, ICD codes are documented in: InjuryHx.ERDestICDCodes1
Hospital.ICDCode11 Original Up to 16 fields available to enter diagnosis as recorded by hospital administration according to ICD codes; applicable to patients admitted/discharged from hospital. For patients discharged directly from the ER, ICD codes are documented in: InjuryHx.ERDestICDCodes1
Hospital.ICDCode12 Original Up to 16 fields available to enter diagnosis as recorded by hospital administration according to ICD codes; applicable to patients admitted/discharged from hospital. For patients discharged directly from the ER, ICD codes are documented in: InjuryHx.ERDestICDCodes1
Hospital.ICDCode13 Original Up to 16 fields available to enter diagnosis as recorded by hospital administration according to ICD codes; applicable to patients admitted/discharged from hospital. For patients discharged directly from the ER, ICD codes are documented in: InjuryHx.ERDestICDCodes1
Hospital.ICDCode14 Original Up to 16 fields available to enter diagnosis as recorded by hospital administration according to ICD codes; applicable to patients admitted/discharged from hospital. For patients discharged directly from the ER, ICD codes are documented in: InjuryHx.ERDestICDCodes1
Hospital.ICDCode15 Original Up to 16 fields available to enter diagnosis as recorded by hospital administration according to ICD codes; applicable to patients admitted/discharged from hospital. For patients discharged directly from the ER, ICD codes are documented in: InjuryHx.ERDestICDCodes1
Hospital.ICDCode16 Original Up to 16 fields available to enter diagnosis as recorded by hospital administration according to ICD codes; applicable to patients admitted/discharged from hospital. For patients discharged directly from the ER, ICD codes are documented in: InjuryHx.ERDestICDCodes1
Hospital.ICDCode2 Original Up to 16 fields available to enter diagnosis as recorded by hospital administration according to ICD codes; applicable to patients admitted/discharged from hospital. For patients discharged directly from the ER, ICD codes are documented in: InjuryHx.ERDestICDCodes1
Hospital.ICDCode3 Original Up to 16 fields available to enter diagnosis as recorded by hospital administration according to ICD codes; applicable to patients admitted/discharged from hospital. For patients discharged directly from the ER, ICD codes are documented in: InjuryHx.ERDestICDCodes1
Hospital.ICDCode4 Original Up to 16 fields available to enter diagnosis as recorded by hospital administration according to ICD codes; applicable to patients admitted/discharged from hospital. For patients discharged directly from the ER, ICD codes are documented in: InjuryHx.ERDestICDCodes1
Hospital.ICDCode5 Original Up to 16 fields available to enter diagnosis as recorded by hospital administration according to ICD codes; applicable to patients admitted/discharged from hospital. For patients discharged directly from the ER, ICD codes are documented in: InjuryHx.ERDestICDCodes1
Hospital.ICDCode6 Original Up to 16 fields available to enter diagnosis as recorded by hospital administration according to ICD codes; applicable to patients admitted/discharged from hospital. For patients discharged directly from the ER, ICD codes are documented in: InjuryHx.ERDestICDCodes1
Hospital.ICDCode7 Original Up to 16 fields available to enter diagnosis as recorded by hospital administration according to ICD codes; applicable to patients admitted/discharged from hospital. For patients discharged directly from the ER, ICD codes are documented in: InjuryHx.ERDestICDCodes1
Hospital.ICDCode8 Original Up to 16 fields available to enter diagnosis as recorded by hospital administration according to ICD codes; applicable to patients admitted/discharged from hospital. For patients discharged directly from the ER, ICD codes are documented in: InjuryHx.ERDestICDCodes1
Hospital.ICDCode9 Original Up to 16 fields available to enter diagnosis as recorded by hospital administration according to ICD codes; applicable to patients admitted/discharged from hospital. For patients discharged directly from the ER, ICD codes are documented in: InjuryHx.ERDestICDCodes1
Hospital.ICDCodeVersion Original 9 == ICD-9
10 == ICD-10
This variable reflects if the ICD code version 9 or version 10 was used. Up to 16 fields are available to enter diagnosis as recorded by hospital administration according to ICD codes.
Hospital.ICPDevice Original 1 == Ventricular
2 == Ventricular +inbuilt sensor
3 == Parenchymal
99 == Other
Type of ICP monitoring device used.
Hospital.ICPDeviceOther Original Free text field with description of which ICP monitoring device was used, in case the device was not listed in the pre-specified list of the CRF. Some patients have had more than one ICP monitoring device, which are listed here.
Hospital.ICPInsDate Original Start date of ICP monitoring.
Hospital.ICPInsTime Original Start time of ICP monitoring Check also "Hospital.ICPInsDate" for the start date.
Hospital.ICPMonitorNo Original Indicates if a patient does not have intracranial pressure (ICP) monitoring. If Hospital.ICPMonitorNo=1, see Hospital.ICUReasonNoICP.
Hospital.ICPMonitorStop Original 0 == No
1 == Yes
If ICP monitoring has stopped or not. Time and date is found in Hospital.ICPRemTime and Hospital.ICPRemDate. Reason for stopping ICP monitoring is found in Hospital.ICPStopReason.
Hospital.ICPMonitorStopReasonOther Original Specifies the "other" reason if the reason for stopping ICP was not on the pre-defined list. Check also "Hospital.ICPStopReason"
Hospital.ICPMonitorYes Original 0 == No
1 == Yes
Indicates if a patient has intracranial pressure (ICP) monitoring. If yes, see Hospital.ICUReasonICP and Hospital.ICPDevice.
Hospital.ICPMontDuration Calculated The duration of ICP monitoring. Calculated variable: Hospital.ICPRemDateTime-Hospital.ICPInsDateTime.
Hospital.ICPRemDate Original Date for stopping ICP monitoring.
Hospital.ICPRemTime Original Time of stopping ICP monitoring.
Hospital.ICPStopReason Original 1 == Clinically improved
2 == ICP stable and < 20 mmHg
3 == Monitor/catheter failure
4 == Patient considered unsalvagable
5 == Patient died
99 == Other
Reason for stopping ICP. Also check Hospital.ICPMonitorStop.
Hospital.ICPUnit Original 1 == ER
2 == OR
3 == Ward
4 == High dependency unit
99 == Other hospital
The type of department the patient was transferred from to the ICU.
Hospital.ICUAdmDate Original Date of Admission to the ICU. In principle the date of injury; date of enrollment and Date of Admission to ICU will match, but in some cases there can be a difference of 1 or 2 days. For example when a patient was injured late at night, it is possible that the consent was only obtained in the morning, hence the date of Study Enrollment will be 1 day later than the date of injury. Or in some hospitals a patient is kept for 24 hours in observation at the ER in a specific unit before being transferred to ICU or Ward. Hence the Date of Admission to ICU or Ward can be 1 or 2 days later. Or if there is no bed available on ICU or Ward for a patient being injured late at night, there can be a delay in admitting the patient.
Hospital.ICUAdmisStatusHaemoStable Original 0 == No
1 == Yes
88 == Unknown
Reflects the status of the patient on admission to the ICU: Haemodynamically stable
Hospital.ICUAdmisStatusIntubated Original 0 == No
1 == Yes
88 == Unknown
Reflects the status of the patient on admission to the ICU: Intubated
Hospital.ICUAdmisStatusMechVent Original 0 == No
1 == Yes
88 == Unknown
Reflects the status of the patient on admission to the ICU: Mechanically ventilated
Hospital.ICUAdmReason Original 1 == Mechanical ventilation
2 == Frequent neurological observations
3 == Haemodynamic invasive monitoring
4 == Extracranial injuries
5 == Neurological operation
6 == Clinical deterioration
99 == Other
Main reason for admission to ICU
Hospital.ICUAdmReasonOther Original Specifies the "other" if the main reason for admission to the ICU was other than the pre-defined list.
Hospital.ICUAdmTime Original Time of admission to the ICU. Check also "Hospital.ICUAdmDate" for the date of admission.
Hospital.ICUCardiacOutput Original 0 == No
1 == Yes
Reflects the type, in case of systemic monitoring on ICU: Cardiac output
Hospital.ICUCatheterICP Original 0 == No
1 == Yes
Reflects if the ICP catheter has been revised in case of ICP monitoring
Hospital.ICUCatheterICPDate Original Reflects the date on which ICP catheter has been revised in case of ICP monitoring Check also "Hospital.ICUCatheterICP"
Hospital.ICUCatheterICPTime Original Reflects the time on which ICP catheter has been revised in case of ICP monitoring Check also "Hospital.ICUCatheterICP" and "Hospital.ICUCatheterICPDate"
Hospital.ICUCentralVenousPress Original 0 == No
1 == Yes
Reflects the type, in case of systemic monitoring on ICU: Central venous pressure
Hospital.ICUComplUTI Original 0 == No
1 == Yes
At discharge, complications and adverse events were summarized. This variable reflects the date of diagnosis of Urinary tract infection in case of systemic complication.
Hospital.ICUDisAdditionalStudiesCoag Original 0 == No
1 == Yes
Intended to provide documentation if the patient was enrolled in the Coagulation sub-study or not.
Hospital.ICUDisAdditionalStudiesTEGRotem Original 0 == No
1 == Yes
Intended to provide documentation if the patient was enrolled in the TEG/ROTEM sub-study or not.
Hospital.ICUDischargeICDCode1 Original The intent here is to register ICD code as recorded in hospital administrative files for patients directly discharged from the ICU. Up to 16 codes can be entered, ICD codes are further captured at ER discharge and at hospital discharge.
Hospital.ICUDischargeICDCode10 Original The intent here is to register ICD code as recorded in hospital administrative files for patients directly discharged from the ICU. Up to 16 codes can be entered, ICD codes are further captured at ER discharge and at hospital discharge.
Hospital.ICUDischargeICDCode11 Original The intent here is to register ICD code as recorded in hospital administrative files for patients directly discharged from the ICU. Up to 16 codes can be entered, ICD codes are further captured at ER discharge and at hospital discharge.
Hospital.ICUDischargeICDCode12 Original The intent here is to register ICD code as recorded in hospital administrative files for patients directly discharged from the ICU. Up to 16 codes can be entered, ICD codes are further captured at ER discharge and at hospital discharge.
Hospital.ICUDischargeICDCode13 Original The intent here is to register ICD code as recorded in hospital administrative files for patients directly discharged from the ICU. Up to 16 codes can be entered, ICD codes are further captured at ER discharge and at hospital discharge.
Hospital.ICUDischargeICDCode14 Original The intent here is to register ICD code as recorded in hospital administrative files for patients directly discharged from the ICU. Up to 16 codes can be entered, ICD codes are further captured at ER discharge and at hospital discharge.
Hospital.ICUDischargeICDCode15 Original The intent here is to register ICD code as recorded in hospital administrative files for patients directly discharged from the ICU. Up to 16 codes can be entered, ICD codes are further captured at ER discharge and at hospital discharge.
Hospital.ICUDischargeICDCode16 Original The intent here is to register ICD code as recorded in hospital administrative files for patients directly discharged from the ICU. Up to 16 codes can be entered, ICD codes are further captured at ER discharge and at hospital discharge.
Hospital.ICUDischargeICDCode2 Original The intent here is to register ICD code as recorded in hospital administrative files for patients directly discharged from the ICU. Up to 16 codes can be entered, ICD codes are further captured at ER discharge and at hospital discharge.
Hospital.ICUDischargeICDCode3 Original The intent here is to register ICD code as recorded in hospital administrative files for patients directly discharged from the ICU. Up to 16 codes can be entered, ICD codes are further captured at ER discharge and at hospital discharge.
Hospital.ICUDischargeICDCode4 Original The intent here is to register ICD code as recorded in hospital administrative files for patients directly discharged from the ICU. Up to 16 codes can be entered, ICD codes are further captured at ER discharge and at hospital discharge.
Hospital.ICUDischargeICDCode5 Original The intent here is to register ICD code as recorded in hospital administrative files for patients directly discharged from the ICU. Up to 16 codes can be entered, ICD codes are further captured at ER discharge and at hospital discharge.
Hospital.ICUDischargeICDCode6 Original The intent here is to register ICD code as recorded in hospital administrative files for patients directly discharged from the ICU. Up to 16 codes can be entered, ICD codes are further captured at ER discharge and at hospital discharge.
Hospital.ICUDischargeICDCode7 Original The intent here is to register ICD code as recorded in hospital administrative files for patients directly discharged from the ICU. Up to 16 codes can be entered, ICD codes are further captured at ER discharge and at hospital discharge.
Hospital.ICUDischargeICDCode8 Original The intent here is to register ICD code as recorded in hospital administrative files for patients directly discharged from the ICU. Up to 16 codes can be entered, ICD codes are further captured at ER discharge and at hospital discharge.
Hospital.ICUDischargeICDCode9 Original The intent here is to register ICD code as recorded in hospital administrative files for patients directly discharged from the ICU. Up to 16 codes can be entered, ICD codes are further captured at ER discharge and at hospital discharge.
Hospital.ICUDischargeICDCodeVersion Original 9 == 9
10 == 10
This variable reflects if the ICD code version 9 or version 10 was used. Up to 16 fields are available to enter diagnosis as recorded by hospital administration according to ICD codes.
Hospital.ICUDischargeStatus Original 1 == Alive
2 == Dead
88 == Unknown
Reflects if patient was alive or dead on discharge from ICU
Hospital.ICUDischargeTo Original 1 == General ward
2 == Other ICU
3 == Other hospital
4 == Rehab unit
5 == Home
6 == Nursing home
7 == Step down/high care unit
88 == Unknown
99 == Other
Reflects location to which the patient was discharged from ICU
Hospital.ICUDischargeToOther Original Specifies the "other" location to which the patient was discharged from ICU Check also "Hospital.ICUDischargeTo"
Hospital.ICUDischDate Original Reflects the ICU Discharge Date
Hospital.ICUDischPTADays Original Pre-defined early endpoints recorded at ICU discharge include: neuroworsening (any episode), time to obeying commands, duration of PTA, duration of ventilation, number of CTs performed and CT progression.
Hospital.ICUDischPTADaysNA Original Reflects if PTA was not applicable. Pre-defined early endpoints recorded at ICU discharge include: neuroworsening (any episode), time to obeying commands, duration of PTA, duration of ventilation, number of CTs performed and CT progression.
Hospital.ICUDischPTAOngoing Original Reflects of PTA was ongoing on ICU discharge. Pre-defined early endpoints recorded at ICU or hospital discharge include: neuroworsening (any episode), time to obeying commands, duration of PTA, number of CTs performed and CT progression.
Hospital.ICUDischTime Original ICU Discharge Time Check also "Hospital.ICUDischDate" for the ICU discharge Date
Hospital.ICUDisComplCardiacArrest Original 0 == No
1 == Yes
At ICU discharge, complications and adverse events were summarized. This variable reflects the presence or absence of Cardiovascular systemic complication.
Hospital.ICUDisComplCRBSI Original 0 == No
1 == Yes
At ICU discharge, complications and adverse events were summarized. This variable reflects the presence or absence of CRBSI (catheter-related bloodstream infection) as systemic complication.
Hospital.ICUDisComplDVT Original 0 == No
1 == Yes
At ICU discharge, complications and adverse events were summarized. This variable reflects the presence or absence of DVT (Deep venous thrombosis) as systemic complication.
Hospital.ICUDisComplIntraCranOther Original 0 == No
1 == Yes
At ICU discharge, complications and adverse events were summarized. This variable reflects the presence or absence of "Other" Intracranial complication (requiring treatment).
Hospital.ICUDisComplIntraCranOtherTxt Original At ICU discharge, complications and adverse events were summarized. This variable specifies the type of "Other" Intracranial complication (requiring treatment).
Hospital.ICUDisComplMeningitis Original 0 == No
1 == Yes
At ICU discharge, complications and adverse events were summarized. This variable reflects the presence or absence of "Meningitis/Ventriculitis" as Intracranial complication (requiring treatment).
Hospital.ICUDisComplMetabolic Original 0 == No
1 == Yes
At ICU discharge, complications and adverse events were summarized. This variable reflects the presence or absence of Metabolic systemic complication.
Hospital.ICUDisComplPE Original 0 == No
1 == Yes
At ICU discharge, complications and adverse events were summarized. This variable reflects the presence or absence of Pulmonary embolus as systemic complication.
Hospital.ICUDisComplPressureSores Original 0 == No
1 == Yes
At ICU discharge, complications and adverse events were summarized. This variable reflects the presence or absence of Pressures sores (decubitus) as systemic complication.
Hospital.ICUDisComplRaisedICP Original 0 == No
1 == Yes
At ICU discharge, complications and adverse events were summarized. This variable reflects the presence or absence of "Raised ICP" as Intracranial complication (requiring treatment).
Hospital.ICUDisComplRespiratoryFailure Original 0 == No
1 == Yes
At ICU discharge, complications and adverse events were summarized. This variable reflects the presence or absence of Respiratory systemic complication.
Hospital.ICUDisComplSeizure Original 0 == No
1 == Yes
At ICU discharge, complications and adverse events were summarized. This variable reflects the presence or absence of "Seizures" Intracranial complication (requiring treatment).
Hospital.ICUDisComplSeromaHematoma Original 0 == No
1 == Yes
At ICU discharge, complications and adverse events were summarized. This variable reflects the presence or absence of "Delayed haematoma" Intracranial complication (requiring treatment).
Hospital.ICUDisComplSystemOther Original 0 == No
1 == Yes
At ICU discharge, complications and adverse events were summarized. This variable reflects the presence or absence of "Other" systemic complication.
Hospital.ICUDisComplSystemOtherTxt Original At ICU discharge, complications and adverse events were summarized. This variable specifies the type of "Other" systemic complication.
Hospital.ICUDisComplVAP Original 0 == No
1 == Yes
At ICU discharge, complications and adverse events were summarized. This variable reflects the presence or absence of VAP (Ventilator associated pneumonia) as systemic complication.
Hospital.ICUDisCTProg Original 0 == No
1 == Yes
Pre-defined early endpoints recorded at ICU discharge include: neuroworsening (any episode), time to obeying commands, duration of PTA, duration of ventilation, number of CTs performed and CT progression.
Hospital.ICUDisCTProgYes Original 1 == Increase in initial lesion
2 == Development of new lesion
Pre-defined early endpoints recorded at ICU discharge include: neuroworsening (any episode), time to obeying commands, duration of PTA, duration of ventilation, number of CTs performed and CT progression. If CT progression was "yes", this reflects if there was Increase in initial lesion or Development of new lesion.
Hospital.ICUDishDurVent Original Pre-defined early endpoints recorded at ICU discharge include: neuroworsening (any episode), time to obeying commands, duration of PTA, duration of ventilation, number of CTs performed and CT progression.
Hospital.ICUDishDurVentNA Original Reflects if Duration of ventilation was not applicable. Pre-defined early endpoints recorded at ICU discharge include: neuroworsening (any episode), time to obeying commands, duration of PTA, duration of ventilation, number of CTs performed and CT progression.
Hospital.ICUDisNeuroworseEpisode Original 0 == No
1 == Yes
Pre-defined early endpoints recorded at ICU discharge include: neuroworsening (any episode), time to obeying commands, duration of PTA, duration of ventilation, number of CTs performed and CT progression.
Hospital.ICUDisNososcomialPneumNum Original At ICU discharge, complications and adverse events were summarized. Presence or absence of VAP (Ventilator associated pneumonia) as systemic complication was recorded. In case presence of VAP was "yes, details on the VAP were recorded. This variable reflects the Nosocomial pneumonia number.
Hospital.ICUDisNumCT Original Pre-defined early endpoints recorded at ICU discharge include: neuroworsening (any episode), time to obeying commands, duration of PTA, duration of ventilation, number of CTs performed and CT progression.
Hospital.ICUDisPatDeadAtICU Original 0 == No
1 == Yes
Reflects if the patient was declared dead on the ICU. Intended as an introductory question for the details on withdrawal of treatment, brain death and organ donation
Hospital.ICUDisPneumAntibiotic1StartDate Original At ICU discharge, complications and adverse events were summarized. Presence or absence of VAP (Ventilator associated pneumonia) as systemic complication was recorded. In case presence of VAP was "yes, details on the VAP were recorded. This reflects if the start date of antibiotic treatment if given.
Hospital.ICUDisPneumAntibiotic2StartDate Original At ICU discharge, complications and adverse events were summarized. Presence or absence of VAP (Ventilator associated pneumonia) as systemic complication was recorded. In case presence of VAP was "yes, details on the VAP were recorded. This reflects if the start date of antibiotic treatment if given.
Hospital.ICUDisPneumAntibiotic3StartDate Original At ICU discharge, complications and adverse events were summarized. Presence or absence of VAP (Ventilator associated pneumonia) as systemic complication was recorded. In case presence of VAP was "yes, details on the VAP were recorded. This reflects if the start date of antibiotic treatment if given.
Hospital.ICUDisPneumAntibiotic4StartDate Original At ICU discharge, complications and adverse events were summarized. Presence or absence of VAP (Ventilator associated pneumonia) as systemic complication was recorded. In case presence of VAP was "yes, details on the VAP were recorded. This reflects if the start date of antibiotic treatment if given.
Hospital.ICUDisPneumAntibioticTreat Original 0 == No
1 == Yes
At ICU discharge, complications and adverse events were summarized. Presence or absence of VAP (Ventilator associated pneumonia) as systemic complication was recorded. In case presence of VAP was "yes, details on the VAP were recorded. This reflects if the antibiotic treatment was given for VAP.
Hospital.ICUDisPneumBacteriaSmpl Original 1 == BAL
2 == Tracheal suction
3 == PDP
4 == Brush
At ICU discharge, complications and adverse events were summarized. Presence or absence of VAP (Ventilator associated pneumonia) as systemic complication was recorded. In case presence of VAP was "yes, details on the VAP were recorded. This reflects if the type of Bacteriological sample taken.
Hospital.ICUDisPneumBloodFiO2pc Original At ICU discharge, complications and adverse events were summarized. Presence or absence of VAP (Ventilator associated pneumonia) as systemic complication was recorded. In case presence of VAP was "yes, details on the VAP were recorded. This reflects the details of blood gas.
Hospital.ICUDisPneumBloodPaCO2mmHg Original At ICU discharge, complications and adverse events were summarized. Presence or absence of VAP (Ventilator associated pneumonia) as systemic complication was recorded. In case presence of VAP was "yes, details on the VAP were recorded. This reflects if the details on blood gas.
Hospital.ICUDisPneumBloodPaO2mmHg Original At ICU discharge, complications and adverse events were summarized. Presence or absence of VAP (Ventilator associated pneumonia) as systemic complication was recorded. In case presence of VAP was "yes, details on the VAP were recorded. This reflects if the details on blood gas.
Hospital.ICUDisPneumBloodPEPcmH2O Original At ICU discharge, complications and adverse events were summarized. Presence or absence of VAP (Ventilator associated pneumonia) as systemic complication was recorded. In case presence of VAP was "yes, details on the VAP were recorded. This reflects if the details on blood gas.
Hospital.ICUDisPneumBloodPF Original At ICU discharge, complications and adverse events were summarized. Presence or absence of VAP (Ventilator associated pneumonia) as systemic complication was recorded. In case presence of VAP was "yes, details on the VAP were recorded. This reflects if the details on blood gas.
Hospital.ICUDisPneumChestX Original 1 == New pneumonia
2 == Modification of an old one
3 == No infiltrate
4 == Diffuse (or patchy) infiltrate
5 == Localized infiltrate
At ICU discharge, complications and adverse events were summarized. Presence or absence of VAP (Ventilator associated pneumonia) as systemic complication was recorded. In case presence of VAP was "yes, details on the VAP were recorded. This reflects the details on the Chest X-ray.
Hospital.ICUDisPneumClinical Original 1 == Fever >=38degC or hypothermia <=36degC
2 == Purulent trachea aspirations
3 == Leukocytes >=12000/ml or <=4000/ml
At ICU discharge, complications and adverse events were summarized. Presence or absence of VAP (Ventilator associated pneumonia) as systemic complication was recorded. In case presence of VAP was "yes, details on the VAP were recorded. This reflects the clinical details on VAP.
Hospital.ICUDisPneumDate Original At ICU discharge, complications and adverse events were summarized. Presence or absence of VAP (Ventilator associated pneumonia) as systemic complication was recorded. In case presence of VAP was "yes, details on the VAP were recorded. This reflects the date of occurrence of the VAP.
Hospital.ICUDisPneumPathogen1 Original At ICU discharge, complications and adverse events were summarized. Presence or absence of VAP (Ventilator associated pneumonia) as systemic complication was recorded. In case presence of VAP was "yes, details on the VAP were recorded. This reflects details on the responsible pathogens for the VAP.
Hospital.ICUDisPneumPathogen1QuantUCFml Original At ICU discharge, complications and adverse events were summarized. Presence or absence of VAP (Ventilator associated pneumonia) as systemic complication was recorded. In case presence of VAP was "yes, details on the VAP were recorded. This reflects details on the responsible pathogens for the VAP.
Hospital.ICUDisPneumPathogen2 Original At ICU discharge, complications and adverse events were summarized. Presence or absence of VAP (Ventilator associated pneumonia) as systemic complication was recorded. In case presence of VAP was "yes, details on the VAP were recorded. This reflects details on the responsible pathogens for the VAP.
Hospital.ICUDisPneumPathogen2QuantUCFml Original At ICU discharge, complications and adverse events were summarized. Presence or absence of VAP (Ventilator associated pneumonia) as systemic complication was recorded. In case presence of VAP was "yes, details on the VAP were recorded. This reflects details on the responsible pathogens for the VAP.
Hospital.ICUDisPneumPathogen3 Original At ICU discharge, complications and adverse events were summarized. Presence or absence of VAP (Ventilator associated pneumonia) as systemic complication was recorded. In case presence of VAP was "yes, details on the VAP were recorded. This reflects details on the responsible pathogens for the VAP.
Hospital.ICUDisPneumPathogen3QuantUCFml Original At ICU discharge, complications and adverse events were summarized. Presence or absence of VAP (Ventilator associated pneumonia) as systemic complication was recorded. In case presence of VAP was "yes, details on the VAP were recorded. This reflects details on the responsible pathogens for the VAP.
Hospital.ICUDisPneumPathogen4 Original At ICU discharge, complications and adverse events were summarized. Presence or absence of VAP (Ventilator associated pneumonia) as systemic complication was recorded. In case presence of VAP was "yes, details on the VAP were recorded. This reflects details on the responsible pathogens for the VAP.
Hospital.ICUDisPneumPathogen4QuantUCFml Original At ICU discharge, complications and adverse events were summarized. Presence or absence of VAP (Ventilator associated pneumonia) as systemic complication was recorded. In case presence of VAP was "yes, details on the VAP were recorded. This reflects details on the responsible pathogens for the VAP.
Hospital.ICUDisPneumSepsis Original 0 == No
1 == Yes
At ICU discharge, complications and adverse events were summarized. Presence or absence of VAP (Ventilator associated pneumonia) as systemic complication was recorded. In case presence of VAP was "yes", details on the VAP were recorded. This reflects details on the sepsis or if septic chock associated.
Hospital.ICUDisSixMonthOutcomeDate Original At ICU discharge, physician estimate of six month outcome was recorded: "Given all current available information, what is, in your subjective opinion, the most likely 6-month outcome of this patient? To be based upon information on discharge ICU". This reflects the date of the prognostic estimate.
Hospital.ICUDisSixMonthOutcomeGOS Original GR == Good Recovery
MD == Moderate Disability
SD == Severe Disability
V == Vegetative state
D == Death
At ICU discharge, physician estimate of six month outcome was recorded: "Given all current available information, what is, in your subjective opinion, the most likely 6-month outcome of this patient? To be based upon information on discharge ICU". This reflects the Expected outcome (GOS).
Hospital.ICUDisSixMonthOutcomeQualification Original 1 == Resident
2 == Junior staff (< 5 years)
3 == Senior staff ( >5 years)
4 == Head of department
At ICU discharge, physician estimate of six month outcome was recorded: "Given all current available information, what is, in your subjective opinion, the most likely 6-month outcome of this patient? To be based upon information on discharge ICU". This reflects the qualification of the physician who provided prognostic estimate on discharge from ICU
Hospital.ICUDisSixMonthOutcomeType Original 1 == ER physician
2 == Intensive care physician
3 == Neurology
4 == Neurosurgery
5 == Traumatology
88 == Unknown
99 == Other
At ICU discharge, physician estimate of six month outcome was recorded: "Given all current available information, what is, in your subjective opinion, the most likely 6-month outcome of this patient? To be based upon information on discharge ICU". The reflects the specialty of the physician who provided prognostic estimate on discharge from ICU
Hospital.ICUDisSixMonthOutcomeUnfavourable Original At ICU discharge, physician estimate of six month outcome was recorded: "Given all current available information, what is, in your subjective opinion, the most likely 6-month outcome of this patient? To be based upon information on discharge ICU". This reflects the risk of unfavorable outcome (D,VS,SD) in %
Hospital.ICUDisSupportWithdrawnDate Original This variable documents date and time at which life prolonging therapy was withdrawn (together with "Hospital.ICUDisSupportWithdrawnTime")
Hospital.ICUDisSupportWithdrawnTime Original This variable documents date and time at which life prolonging therapy was withdrawn (together with "Hospital.ICUDisSupportWithdrawnDate")
Hospital.ICUDisTimeToObeyCommands Original Pre-defined early endpoints recorded at ICU discharge include: neuroworsening (any episode), time to obeying commands, duration of PTA, duration of ventilation, number of CTs performed and CT progression.
Hospital.ICUDisTimeToObeyCommandsNA Original Pre-defined early endpoints recorded at ICU discharge include: neuroworsening (any episode), time to obeying commands, duration of PTA, duration of ventilation, number of CTs performed and CT progression. This reflects if 'Time to obey commands' was Not applicable.
Hospital.ICUDisWithdrawalTreatmentDecisionDate Original Investigators were requested to record the details of Withdrawal of Treatment or Life support if applicable.
Hospital.ICUDisWithdrawalTreatmentDecisionTime Original Investigators were requested to record the details of Withdrawal of Treatment or Life support if applicable.
Hospital.ICUDisWithdrawlTreatmentDecision Original 1 == Multi disciplinary
2 == By a single physician
3 == With relatives
Investigators were requested to record the details of Withdrawal of Treatment or Life support if applicable.
Hospital.ICUEndTidalCO2 Original 0 == No
1 == Yes
Reflects the type, in case of systemic monitoring on ICU: End Tidal CO2
Hospital.ICUGCSDischargeEyes Original O == Untestable (other)
S == Untestable (swollen)
1 == 1-None
2 == 2-To pain
3 == 3-To speech
4 == 4-Spontaneously
88 == Unknown
Eye opening score for GCS at ICU discharge.
Hospital.ICUGCSDischargeMotor Original UN == Unknown
P == Untestable (Deep sedation/paralyzed)
O == Untestable (Other)
1 == 1-None
2 == 2-Abnormal extension
3 == 3-Abnormal flexion
4 == 4-Normal flexion/withdrawal
5 == 5-Localizes to pain
6 == 6-Obeys command
Motor score for GCS at ICU discharge.
Hospital.ICUGCSDischargeScore Calculated GCS score at ICU discharge.
Hospital.ICUGCSDischargeVerbal Original UN == Unknown
O == Untestable (Other)
P == Untestable (tracheotomy/endotracheal tube)
T == Untestable (tracheotomy/endotracheal tube)
1 == 1-None
2 == 2-Incomprehensible sound
3 == 3-Inappropriate words
4 == 4-Confused
5 == 5-Oriented
Verbal score for GCS at ICU discharge.
Hospital.ICUInvasiveBP Original 0 == No
1 == Yes
Reflects the type, in case of systemic monitoring on ICU: Invasive BP monitoring
Hospital.ICUProblemsICP Original 0 == No
1 == Yes
In case of brain specific monitoring in the ICU, all details on the ICP monitoring were recorded. This variable reflects Problems in ICP monitoring.
Hospital.ICUProblemsICPYes Original 1 == Accidental catheter removal
2 == Catheter obstruction/failure
3 == Suspicion of inaccurate measurement
In case of brain specific monitoring in the ICU, all details on the ICP monitoring were recorded. This variable explains the Problems in ICP monitoring if applicable.
Hospital.ICUPulseOximetry Original 0 == No
1 == Yes
Reflects the type, in case of systemic monitoring on ICU: Pulse oximetry
Hospital.ICURaisedICP Original 0 == No
1 == Yes, controlled
2 == Yes, refractory
In case of brain specific monitoring in the ICU, all details on the ICP monitoring were recorded. This variable reflects if there was Raised ICP (sustained).
Hospital.ICUReasonForTypeICPMont Original 1 == Routine in our department
2 == Not routine, but enlarged ventricles
3 == No parenchymal device available
99 == Other
In case of brain specific monitoring in the ICU, all details on the ICP monitoring were recorded. This variable reflects WHY Question: reason for choosing ventricular monitor
Hospital.ICUReasonForTypeICPMontPare Original 1 == Routine in our department
2 == Not routine, but small ventricles
3 == Mainly motivated by time of day
4 == No OR available for placement ventr. catheter
5 == Failed implantation ventricular catheter
99 == Other
In case of brain specific monitoring in the ICU, all details on the ICP monitoring were recorded. This variable reflects WHY Question: reason for choosing parenchymal monitor.
Hospital.ICUReasonForTypeICUMontOther Original In case of brain specific monitoring in the ICU, all details on the ICP monitoring were recorded. This variable reflects "Other Reason of choice for ventricular/ventricular+sensor monitoring"
Hospital.ICUReasonForTypeICUMontParOther Original In case of brain specific monitoring in the ICU, all details on the ICP monitoring were recorded. This variable reflects 'Other Reason of choice for parenchymal sensor'.
Hospital.ICUReasonICP Original 1 == Guideline criteria
2 == Radiological signs raised ICP
3 == Clinical suspicion raised ICP
4 == Anaesthesia or mechanical ventilation required for extracranial injuries
5 == To inform surgical indication for mass lesion
99 == Other
In case of brain specific monitoring in the ICU, all details on the ICP monitoring were recorded. This variable reflects WHY Question: documents reason for monitoring ICP in patient admitted to ICU
Hospital.ICUReasonICPOther Original In case of brain specific monitoring in the ICU, all details on the ICP monitoring were recorded. This variable is a free text field for description of why the patient has ICP monitoring if there is another reason than pre-specified in Hospital.ICUReasonICP.
Hospital.ICUReasonNoICP Original 1 == GCS >8
2 == No radiological signs of raised ICP
3 == Risk of raised ICP considered low
4 == Patient considered unsalvageable
5 == Coagulopathy
6 == Use of anticoagulants or platelet aggregation inhibitors
7 == No device available
8 == Not local policy to monitor ICP
9 == Too costly
99 == Other
In case of brain specific monitoring in the ICU, all details on the ICP monitoring were recorded. This variable reflects WHY Question: documents reason for not monitoring ICP in patient admitted to ICU
Hospital.ICUReasonNoICPOther Original In case of brain specific monitoring in the ICU, all details on the ICP monitoring were recorded. This variable is a free text field for description of the reason why ICP has not been monitored in ICU patient if there is another reason than pre-specified in Hospital.ICUReasonNoICP.
Hospital.MonContEGG Original 0 == No
1 == Yes
Beside brain specific ICP monitoring in the ICU, details were recorded on other types of monitoring in the ICU. This variable reflects if there was continuous EEG monitoring.
Hospital.MonContEGGDuration Original Beside brain specific ICP monitoring in the ICU, details were recorded on other types of monitoring in the ICU. This variable reflects the duration if there was continuous EEG monitoring.
Hospital.MonECoG Original 0 == No
1 == Yes
Beside brain specific ICP monitoring in the ICU, details were recorded on other types of monitoring in the ICU. This variable reflects if there was continuous ECoG monitoring.
Hospital.MonECoGDuration Original Beside brain specific ICP monitoring in the ICU, details were recorded on other types of monitoring in the ICU. This variable reflects the duration if there was continuous EEG monitoring.
Hospital.MonJugularDesatEpisodes Original 0 == No
1 == Yes
77 == N/A
Beside brain specific ICP monitoring in the ICU, details were recorded on other types of monitoring in the ICU. This variable reflects if there were Jugular desaturation episodes (<50%).
Hospital.MonJugularSatDuration Original Beside brain specific ICP monitoring in the ICU, details were recorded on other types of monitoring in the ICU. This variable reflects the duration if there was Jugular oximetry.
Hospital.MonJugularSatStopReason Original 1 == Monitor/catheter failure
2 == Patient considered unsalvageable
3 == Patient died
4 == Clinically no longer required
Beside brain specific ICP monitoring in the ICU, details were recorded on other types of monitoring in the ICU. This variable reflects the reason for stopping if there was Jugular oximetry.
Hospital.MonJugularSatUsed Original 0 == No
1 == Yes
Beside brain specific ICP monitoring in the ICU, details were recorded on other types of monitoring in the ICU. This variable reflects if there was Jugular oximetry.
Hospital.MonLicoxDuration Original Beside brain specific ICP monitoring in the ICU, details were recorded on other types of monitoring in the ICU. This variable reflects the duration if there was Brain tissue PO2 monitoring.
Hospital.MonLicoxPO2 Original 0 == No
1 == Yes
77 == N/A
Beside brain specific ICP monitoring in the ICU, details were recorded on other types of monitoring in the ICU. This variable reflects if there was Brain tissue PO2 <15mmHg monitoring.
Hospital.MonLicoxStopReason Original 1 == Monitor/catheter failure
2 == Patient considered unsalvageable
3 == Patient died
4 == Clinically no longer required
Beside brain specific ICP monitoring in the ICU, details were recorded on other types of monitoring in the ICU. This variable reflects the reason for stopping if there was Brain tissue PO2 monitoring.
Hospital.MonLicoxUsed Original 0 == No
1 == Yes
Beside brain specific ICP monitoring in the ICU, details were recorded on other types of monitoring in the ICU. This variable reflects if there was Brain tissue PO2 monitoring.
Hospital.MonMicrodialysisDuration Original Beside brain specific ICP monitoring in the ICU, details were recorded on other types of monitoring in the ICU. This variable reflects the duration if there was Microdialysis.
Hospital.MonMicrodialysisStopReason Original 1 == Monitor/catheter failure
2 == Patient considered unsalvageable
3 == Patient died
4 == Clinically no longer required
Beside brain specific ICP monitoring in the ICU, details were recorded on other types of monitoring in the ICU. This variable reflects the reason for stopping if there was Microdialysis.
Hospital.MonMicrodialysisUsed Original 0 == No
1 == Yes
Beside brain specific ICP monitoring in the ICU, details were recorded on other types of monitoring in the ICU. This variable reflects if there was Microdialysis.
Hospital.MonTranscranDoppler Original 0 == No
1 == Yes
Beside brain specific ICP monitoring in the ICU, details were recorded on other types of monitoring in the ICU. This variable reflects if there was Transcranial Doppler monitoring.
Hospital.OrganDonationDate Original Reflects the date of organ donation in case of Withdrawal of life-sustaining measures, if applicable.
Hospital.OrganDonationTime Original Reflects the time of organ donation in case of Withdrawal of life-sustaining measures, if applicable.
Hospital.SixMonthOutcomeDate Original At hospital discharge, physician estimate of six month outcome was recorded: "Given all current available information, what is, in your subjective opinion, the most likely 6-month outcome of this patient? To be based upon information on discharge from hospital". This same information was also recorded for discharge specifically from ICU. This reflects the Date of prognostic estimate.
Hospital.SixMonthOutcomeGOS Original GR == Good Recovery
MD == Moderate Disability
SD == Severe Disability
V == Vegetative state
D == Death
At hospital discharge, physician estimate of six month outcome was recorded: "Given all current available information, what is, in your subjective opinion, the most likely 6-month outcome of this patient? To be based upon information on discharge from hospital". This same information was also recorded for discharge specifically from ICU. This reflects the Expected outcome (GOS).
Hospital.SixMonthOutcomeQualification Original 1 == Resident
2 == Junior staff (< 5 years)
3 == Senior staff ( >5 years)
4 == Head of department
At hospital discharge, physician estimate of six month outcome was recorded: "Given all current available information, what is, in your subjective opinion, the most likely 6-month outcome of this patient? To be based upon information on discharge from hospital". This same information was also recorded for discharge specifically from ICU. This reflects the qualification of the physician who provided prognostic estimate on hospital discharge
Hospital.SixMonthOutcomeType Original 1 == ER physician
2 == Intensive care physician
3 == Neurology
4 == Neurosurgery
5 == Traumatology
88 == Unknown
99 == Other
At hospital discharge, physician estimate of six month outcome was recorded: "Given all current available information, what is, in your subjective opinion, the most likely 6-month outcome of this patient? To be based upon information on discharge from hospital". This same information was also recorded for discharge specifically from ICU. This reflects the type of the physician who provided prognostic estimate on hospital discharge.
Hospital.SixMonthOutcomeUnfavourable Original At hospital discharge, physician estimate of six month outcome was recorded: "Given all current available information, what is, in your subjective opinion, the most likely 6-month outcome of this patient? To be based upon information on discharge from hospital". This same information was also recorded for discharge specifically from ICU. This reflects the Risk of unfavorable outcome (D,VS,SD) in %
Hospital.SupportWithdrawnDate Original Investigators were requested to record the details of Withdrawal of Treatment or Life support if applicable.
Hospital.SupportWithdrawnTime Original Investigators were requested to record the details of Withdrawal of Treatment or Life support if applicable.
Hospital.TimeSinceICUAdmisDeath Original Investigators were requested to record the details of Withdrawal of Treatment or Life support if applicable. This reflects the time between admission in the ICU and death
Hospital.WardAdmDate Original Date of admission to the ward In principle the date of injury; date of enrollment and Date of Admission to Ward will match, but in some cases there can be a difference of 1 or 2 days. For example when a patient was injured late at night, it is possible that the consent was only obtained in the morning, hence the date of Study Enrollment will be 1 day later than the date of injury. Or in some hospitals a patient is kept for 24 hours in observation at the ER in a specific unit before being transferred to ICU or Ward. Hence the Date of Admission to ICU or Ward can be 1 or 2 days later. Or if there is no bed available on ICU or Ward for a patient being injured late at night, there can be a delay in admitting the patient.
Hospital.WardAdmReason Original 4 == Extracranial injuries
7 == CT abnormalities
8 == Clinical observation for TBI
9 == No ICU bed available
10 == Could be discharged home, but no adequate supervision
99 == Other
WHY question: documents main reason for admission to ward (and not to ICU or discharge home)
Hospital.WardAdmReasonOther Original If the variable WardAdmReason was set to Other the reason for admission to the ward is filled in here.
Hospital.WardAdmTime Original Time of admission to the ward
Hospital.WithdrawalTreatmentDecision Original 1 == Multi disciplinary
2 == By a single physician
3 == With relatives
Intended only to be scored if a medical decision was made to withdraw active treatment because of anticipated poor prognosis. However, some investigators may have scored this when patients had recovered to an extent that active treatment was no longer necessary.
Hospital.WithdrawalTreatmentDecisionDate Original Investigators were requested to record the details of Withdrawal of Treatment or Life support if applicable. Intended only to be scored if a medical decision was made to withdraw active treatment because of anticipated poor prognosis. However, some investigators may have scored this when patients had recovered to an extent that active treatment was no longer necessary.
Hospital.WithdrawalTreatmentDecisionTime Original Investigators were requested to record the details of Withdrawal of Treatment or Life support if applicable. Intended only to be scored if a medical decision was made to withdraw active treatment because of anticipated poor prognosis. However, some investigators may have scored this when patients had recovered to an extent that active treatment was no longer necessary.
HourlyMeasurements.DaySinceInjury Derived Calculated from HourlyValues.HVDate and Subject.DateInj
HourlyMeasurements.HVCPP Calculated Normalized data for HVCPP2, HVCPP 4 etc. Calculated from MAP-ICP (HVSBP+2*HVDBP)/3-HVICP.
HourlyMeasurements.HVDateTime Original The date and time manually entered for the measurements in HourlyValues at time 2,4,6... are combined into this variable to match the entries in the HourlyMeasurements variables for HVSBP, HVDBP, HVICP.
HourlyMeasurements.HVDBP Derived All diastolic blood pressures combined into one variable, measured twice hourly. To get intended measurement time, see HourlyMeasurements.HVMeasurementDateTime.
HourlyMeasurements.HVICP Derived All intracranial pressures combined into one variable, measured twice hourly. To get intended measurement time, see HourlyMeasurements.HVMeasurementDateTime.
HourlyMeasurements.HVMeasurementDateTime Derived The intended date and time for all hourly values measurements (HVSBP, HVDBP, HVICP, HVCPP) derived from HVDate+HVTimeX where HVTimeX is HVTime2->02.00, HVTime4->04.00,..., HVTime24->23.59.
HourlyMeasurements.HVSBP Derived All systolic blood pressures combined into one variable, measured twice hourly. To get intended measurement time, see HourlyMeasurements.HVMeasurementDateTime.
HourlyMeasurements.HVTIL Derived Investigators were requested to document any change in TIL at 4 hour intervals (6 times per day), in a way that corresponds with the documentation of hourly values (04:00-08:00-12:00-16:00-20:00-24:00). This variable combines the hourly TIL values and represents in a long format these hourly measurements. See also HourlyValues.HVTIL4, HourlyValues.HVTIL8, HourlyValues.HVTIL12, HourlyValues.HVTIL16, HourlyValues.HVTIL20, HourlyValues.HVTIL24
HourlyValues.HourlyValueAccurate Original 0 == No
1 == Yes
2 == Doubtful
Are the measured values for ICP over this day considered to be accurate? An explanation can be found in HourlyValues.HourlyValueNotAccurateProblems. Associated with the date in HourlyValues.HVDate.
HourlyValues.HourlyValueICPDiscontinued Original 0 == No
1 == Yes
Answer to the question: "Was active ICP treatment discontinued (due to poor prognosis)?"
HourlyValues.HourlyValueLevelABP Original 1 == Right atrium
2 == Level of arterial catheter
99 == Other
Differences in level of zeroing the arterial blood pressure transducer may affect calculations of CPP and comparisons between centres.
HourlyValues.HourlyValueLevelABPOther Original A free text description of the level of ABP transducer if HourlyValues.HourlyValueLevelABP is "other".
HourlyValues.HourlyValueLevelICP Original 1 == Foramen of Monro
2 == Same level as ABP
3 == Meatus externus (ear)
Only applicable in case ICP monitored; Differences in level of zeroing ICP may affect calculation of CPP and comparisons between centres.
HourlyValues.HourlyValueNotAccurateProblems Original Explanation in free text of the variable HourlyValues.HourlyValueAccurate. Associated with the date in HourlyValues.HVDate.
HourlyValues.HVCPP10 Calculated The cerebral perfusion pressure, CPP, associated with the HourlyValues.HVDateTime10. Calculated by the equation HVCPP10 = (HVSBP10+ 2*HVDBP10)/3-HVICP10. It is set to NA if any of the values in the equation is missing or HVICP10 is 0.
HourlyValues.HVCPP12 Calculated The cerebral perfusion pressure, CPP, associated with the HourlyValues.HVDateTime12. Calculated by the equation HVCPP12 = (HVSBP12+ 2*HVDBP12)/3-HVICP12. It is set to NA if any of the values in the equation is missing or HVICP12 is 0.
HourlyValues.HVCPP14 Calculated The cerebral perfusion pressure, CPP, associated with the HourlyValues.HVDateTime14. Calculated by the equation HVCPP14 = (HVSBP14+ 2*HVDBP14)/3-HVICP14. It is set to NA if any of the values in the equation is missing or HVICP14 is 0.
HourlyValues.HVCPP16 Calculated The cerebral perfusion pressure, CPP, associated with the HourlyValues.HVDateTime16. Calculated by the equation HVCPP16 = (HVSBP16+ 2*HVDBP16)/3-HVICP16. It is set to NA if any of the values in the equation is missing or HVICP16 is 0.
HourlyValues.HVCPP18 Calculated The cerebral perfusion pressure, CPP, associated with the HourlyValues.HVDateTime18. Calculated by the equation HVCPP18 = (HVSBP18+ 2*HVDBP18)/3-HVICP18. It is set to NA if any of the values in the equation is missing or HVICP18 is 0.
HourlyValues.HVCPP2 Calculated The cerebral perfusion pressure, CPP, associated with the HourlyValues.HVDateTime2. This variable is calculated by HVCPP2 = (HVSBP2+2*HVDBP2)/3 - HVICP2. It is set to NA if any of the values in the equation is missing or HVICP2 is 0.
HourlyValues.HVCPP20 Calculated The cerebral perfusion pressure, CPP, associated with the HourlyValues.HVDateTime20. Calculated by the equation HVCPP20 = (HVSBP20+ 2*HVDBP20)/3-HVICP20. It is set to NA if any of the values in the equation is missing or HVICP20 is 0.
HourlyValues.HVCPP22 Calculated The cerebral perfusion pressure, CPP, associated with the HourlyValues.HVDateTime22. Calculated by the equation HVCPP22 = (HVSBP22+ 2*HVDBP22)/3-HVICP22. It is set to NA if any of the values in the equation is missing or HVICP22 is 0.
HourlyValues.HVCPP24 Calculated The cerebral perfusion pressure, CPP, associated with the HourlyValues.HVDateTime24. Calculated by the equation HVCPP24 = (HVSBP24+ 2*HVDBP24)/3-HVICP24. It is set to NA if any of the values in the equation is missing or HVICP24 is 0.
HourlyValues.HVCPP4 Calculated The cerebral perfusion pressure, CPP, associated with the HourlyValues.HVDateTime4. This variable is calculated by the equation HVCPP4 = (HVSBP4+ 2*HVDBP4)/3-HVICP4. It is set to NA if any of the values in the equation is missing or HVICP2 is 0.
HourlyValues.HVCPP6 Calculated The cerebral perfusion pressure, CPP, associated with the HourlyValues.HVDateTime6. Calculated by the equation HVCPP6 = (HVSBP6+ 2*HVDBP6)/3-HVICP6. It is set to NA if any of the values in the equation is missing or HVICP6 is 0.
HourlyValues.HVCPP8 Calculated The cerebral perfusion pressure, CPP, associated with the HourlyValues.HVDateTime8. Calculated by the equation HVCPP8 = (HVSBP8+ 2*HVDBP8)/3-HVICP8. It is set to NA if any of the values in the equation is missing or HVICP8 is 0.
HourlyValues.HVDate Original The date the hourly values are measured.
HourlyValues.HVDBP10 Original The diastolic blood pressure associated with HourlyValues.HVDateTime10.
HourlyValues.HVDBP12 Original The diastolic blood pressure associated with HourlyValues.HVDateTime12.
HourlyValues.HVDBP14 Original The diastolic blood pressure associated with HourlyValues.HVDateTime14.
HourlyValues.HVDBP16 Original The diastolic blood pressure associated with HourlyValues.HVDateTime16.
HourlyValues.HVDBP18 Original The diastolic blood pressure associated with HourlyValues.HVDateTime18.
HourlyValues.HVDBP2 Original The diastolic blood pressure associated with HourlyValues.HVDateTime2.
HourlyValues.HVDBP20 Original The diastolic blood pressure associated with HourlyValues.HVDateTime20.
HourlyValues.HVDBP22 Original The diastolic blood pressure associated with HourlyValues.HVDateTime22.
HourlyValues.HVDBP24 Original The diastolic blood pressure associated with HourlyValues.HVDateTime24.
HourlyValues.HVDBP4 Original The diastolic blood pressure associated with HourlyValues.HVDateTime4.
HourlyValues.HVDBP6 Original The diastolic blood pressure associated with HourlyValues.HVDateTime6.
HourlyValues.HVDBP8 Original The diastolic blood pressure associated with HourlyValues.HVDateTime8.
HourlyValues.HVICP10 Original The intracranial pressure associated with HourlyValues.HVDateTime10.
HourlyValues.HVICP12 Original The intracranial pressure associated with HourlyValues.HVDateTime12.
HourlyValues.HVICP14 Original The intracranial pressure associated with HourlyValues.HVDateTime14.
HourlyValues.HVICP16 Original The intracranial pressure associated with HourlyValues.HVDateTime16.
HourlyValues.HVICP18 Original The intracranial pressure associated with HourlyValues.HVDateTime18.
HourlyValues.HVICP2 Original The intracranial pressure associated with HourlyValues.HVDateTime2.
HourlyValues.HVICP20 Original The intracranial pressure associated with HourlyValues.HVDateTime20.
HourlyValues.HVICP22 Original The intracranial pressure associated with HourlyValues.HVDateTime22.
HourlyValues.HVICP24 Original The intracranial pressure associated with HourlyValues.HVDateTime24.
HourlyValues.HVICP4 Original The intracranial pressure associated with HourlyValues.HVDateTime4.
HourlyValues.HVICP6 Original The intracranial pressure associated with HourlyValues.HVDateTime6.
HourlyValues.HVICP8 Original The intracranial pressure associated with HourlyValues.HVDateTime8.
HourlyValues.HVSBP10 Original The systolic blood pressure associated with HourlyValues.HVDateTime10.
HourlyValues.HVSBP12 Original The systolic blood pressure associated with HourlyValues.HVDateTime12.
HourlyValues.HVSBP14 Original The systolic blood pressure associated with HourlyValues.HVDateTime14.
HourlyValues.HVSBP16 Original The systolic blood pressure associated with HourlyValues.HVDateTime16.
HourlyValues.HVSBP18 Original The systolic blood pressure associated with HourlyValues.HVDateTime18.
HourlyValues.HVSBP2 Original The systolic blood pressure associated with HourlyValues.HVDateTime2.
HourlyValues.HVSBP20 Original The systolic blood pressure associated with HourlyValues.HVDateTime20.
HourlyValues.HVSBP22 Original The systolic blood pressure associated with HourlyValues.HVDateTime22.
HourlyValues.HVSBP24 Original The systolic blood pressure associated with HourlyValues.HVDateTime24.
HourlyValues.HVSBP4 Original The systolic blood pressure associated with HourlyValues.HVDateTime4.
HourlyValues.HVSBP6 Original The systolic blood pressure associated with HourlyValues.HVDateTime6.
HourlyValues.HVSBP8 Original The systolic blood pressure associated with HourlyValues.HVDateTime8.
HourlyValues.HVTIL12 Original 0 == No change
1 == Increasing intensity
2 == Decreasing intensity
Investigators were requested to document any change in TIL at 4 hour intervals (6 times per day), in a way that corresponds with the documentation of hourly values (04:00-08:00-12:00-16:00-20:00-24:00)
HourlyValues.HVTIL16 Original 0 == No change
1 == Increasing intensity
2 == Decreasing intensity
Investigators were requested to document any change in TIL at 4 hour intervals (6 times per day), in a way that corresponds with the documentation of hourly values (04:00-08:00-12:00-16:00-20:00-24:00)
HourlyValues.HVTIL20 Original 0 == No change
1 == Increasing intensity
2 == Decreasing intensity
Investigators were requested to document any change in TIL at 4 hour intervals (6 times per day), in a way that corresponds with the documentation of hourly values (04:00-08:00-12:00-16:00-20:00-24:00)
HourlyValues.HVTIL24 0 == No change
1 == Increasing intensity
2 == Decreasing intensity
Investigators were requested to document any change in TIL at 4 hour intervals (6 times per day), in a way that corresponds with the documentation of hourly values (04:00-08:00-12:00-16:00-20:00-24:00)
HourlyValues.HVTIL4 Original 0 == No change
1 == Increasing intensity
2 == Decreasing intensity
Investigators were requested to document any change in TIL at 4 hour intervals (6 times per day), in a way that corresponds with the documentation of hourly values (04:00-08:00-12:00-16:00-20:00-24:00)
HourlyValues.HVTIL8 0 == No change
1 == Increasing intensity
2 == Decreasing intensity
Investigators were requested to document any change in TIL at 4 hour intervals (6 times per day), in a way that corresponds with the documentation of hourly values (04:00-08:00-12:00-16:00-20:00-24:00)
HourlyValues.HVTILChangeReason12 1 == Intensified: Clinical deterioration
2 == Intensified: Suspicion of increased of ICP (not measured)
3 == Intensified: Increased ICP (documented)
4 == Intensified:Clinical decision to target other mechanism
5 == Intensified:Change of doctor (different shift)
6 == Decreasing:Clinical improvement
7 == Decreasing:Adequate control over ICP
8 == Decreasing:Upper treatment limit reached/past
9 == Decreasing: Further treatment considered futile
10 == Decreasing: Change of doctor (different shift)
WHY question: Differentiated for: - Intensified: Clinical deterioration - Intensified: Suspicion of increased of ICP - Intensified: increased ICP (documented) - Intensified:Clinical decision to target other mechanism - Intensified:Change of doctor (different shift) - Decreasing:Clinical improvement - Decreasing:Adequate control over ICP - Decreasing:Upper treatment limit reached/past - Decreasing: Further treatment considered futile - Decreasing: Change of doctor (different shift). The hours at which the reasons for change are documented should correspond to the hours for documentation of any change in TIL; documentation of reason is only required in case of a change in TIL
HourlyValues.HVTILChangeReason16 1 == Intensified: Clinical deterioration
2 == Intensified: Suspicion of increased of ICP (not measured)
3 == Intensified: Increased ICP (documented)
4 == Intensified:Clinical decision to target other mechanism
5 == Intensified:Change of doctor (different shift)
6 == Decreasing:Clinical improvement
7 == Decreasing:Adequate control over ICP
8 == Decreasing:Upper treatment limit reached/past
9 == Decreasing: Further treatment considered futile
10 == Decreasing: Change of doctor (different shift)
WHY question: Differentiated for: - Intensified: Clinical deterioration - Intensified: Suspicion of increased of ICP - Intensified: increased ICP (documented) - Intensified:Clinical decision to target other mechanism - Intensified:Change of doctor (different shift) - Decreasing:Clinical improvement - Decreasing:Adequate control over ICP - Decreasing:Upper treatment limit reached/past - Decreasing: Further treatment considered futile - Decreasing: Change of doctor (different shift). The hours at which the reasons for change are documented should correspond to the hours for documentation of any change in TIL; documentation of reason is only required in case of a change in TIL
HourlyValues.HVTILChangeReason20 1 == Intensified: Clinical deterioration
2 == Intensified: Suspicion of increased of ICP (not measured)
3 == Intensified: Increased ICP (documented)
4 == Intensified:Clinical decision to target other mechanism
5 == Intensified:Change of doctor (different shift)
6 == Decreasing:Clinical improvement
7 == Decreasing:Adequate control over ICP
8 == Decreasing:Upper treatment limit reached/past
9 == Decreasing: Further treatment considered futile
10 == Decreasing: Change of doctor (different shift)
WHY question: Differentiated for: - Intensified: Clinical deterioration - Intensified: Suspicion of increased of ICP - Intensified: increased ICP (documented) - Intensified:Clinical decision to target other mechanism - Intensified:Change of doctor (different shift) - Decreasing:Clinical improvement - Decreasing:Adequate control over ICP - Decreasing:Upper treatment limit reached/past - Decreasing: Further treatment considered futile - Decreasing: Change of doctor (different shift). The hours at which the reasons for change are documented should correspond to the hours for documentation of any change in TIL; documentation of reason is only required in case of a change in TIL
HourlyValues.HVTILChangeReason24 1 == Intensified: Clinical deterioration
2 == Intensified: Suspicion of increased of ICP (not measured)
3 == Intensified: Increased ICP (documented)
4 == Intensified:Clinical decision to target other mechanism
5 == Intensified:Change of doctor (different shift)
6 == Decreasing:Clinical improvement
7 == Decreasing:Adequate control over ICP
8 == Decreasing:Upper treatment limit reached/past
9 == Decreasing: Further treatment considered futile
10 == Decreasing: Change of doctor (different shift)
WHY question: Differentiated for: - Intensified: Clinical deterioration - Intensified: Suspicion of increased of ICP - Intensified: increased ICP (documented) - Intensified:Clinical decision to target other mechanism - Intensified:Change of doctor (different shift) - Decreasing:Clinical improvement - Decreasing:Adequate control over ICP - Decreasing:Upper treatment limit reached/past - Decreasing: Further treatment considered futile - Decreasing: Change of doctor (different shift). The hours at which the reasons for change are documented should correspond to the hours for documentation of any change in TIL; documentation of reason is only required in case of a change in TIL
HourlyValues.HVTILChangeReason4 1 == Intensified: Clinical deterioration
2 == Intensified: Suspicion of increased of ICP (not measured)
3 == Intensified: Increased ICP (documented)
4 == Intensified:Clinical decision to target other mechanism
5 == Intensified:Change of doctor (different shift)
6 == Decreasing:Clinical improvement
7 == Decreasing:Adequate control over ICP
8 == Decreasing:Upper treatment limit reached/past
9 == Decreasing: Further treatment considered futile
10 == Decreasing: Change of doctor (different shift)
WHY question: Differentiated for: - Intensified: Clinical deterioration - Intensified: Suspicion of increased of ICP - Intensified: increased ICP (documented) - Intensified:Clinical decision to target other mechanism - Intensified:Change of doctor (different shift) - Decreasing:Clinical improvement - Decreasing:Adequate control over ICP - Decreasing:Upper treatment limit reached/past - Decreasing: Further treatment considered futile - Decreasing: Change of doctor (different shift). The hours at which the reasons for change are documented should correspond to the hours for documentation of any change in TIL; documentation of reason is only required in case of a change in TIL
HourlyValues.HVTILChangeReason8 1 == Intensified: Clinical deterioration
2 == Intensified: Suspicion of increased of ICP (not measured)
3 == Intensified: Increased ICP (documented)
4 == Intensified:Clinical decision to target other mechanism
5 == Intensified:Change of doctor (different shift)
6 == Decreasing:Clinical improvement
7 == Decreasing:Adequate control over ICP
8 == Decreasing:Upper treatment limit reached/past
9 == Decreasing: Further treatment considered futile
10 == Decreasing: Change of doctor (different shift)
WHY question: Differentiated for: - Intensified: Clinical deterioration - Intensified: Suspicion of increased of ICP - Intensified: increased ICP (documented) - Intensified:Clinical decision to target other mechanism - Intensified:Change of doctor (different shift) - Decreasing:Clinical improvement - Decreasing:Adequate control over ICP - Decreasing:Upper treatment limit reached/past - Decreasing: Further treatment considered futile - Decreasing: Change of doctor (different shift). The hours at which the reasons for change are documented should correspond to the hours for documentation of any change in TIL; documentation of reason is only required in case of a change in TIL
HourlyValues.HVTime10 Original Investigators were requested to document hourly values every 2 hours (12 times per day) for all patients receiving ICP monitoring. The timeperiods were pre-specified (02:00-24:00); however, investigators may have entered values at different times and have then entered the time of obtaining hourly values; a possible confusion may exist if investigators entered the time of documenting the hourly values rather than the time at which they were obtained.
HourlyValues.HVTime12 Original Investigators were requested to document hourly values every 2 hours (12 times per day) for all patients receiving ICP monitoring. The timeperiods were pre-specified (02:00-24:00); however, investigators may have entered values at different times and have then entered the time of obtaining hourly values; a possible confusion may exist if investigators entered the time of documenting the hourly values rather than the time at which they were obtained.
HourlyValues.HVTime14 Original Investigators were requested to document hourly values every 2 hours (12 times per day) for all patients receiving ICP monitoring. The timeperiods were pre-specified (02:00-24:00); however, investigators may have entered values at different times and have then entered the time of obtaining hourly values; a possible confusion may exist if investigators entered the time of documenting the hourly values rather than the time at which they were obtained.
HourlyValues.HVTime16 Original Investigators were requested to document hourly values every 2 hours (12 times per day) for all patients receiving ICP monitoring. The timeperiods were pre-specified (02:00-24:00); however, investigators may have entered values at different times and have then entered the time of obtaining hourly values; a possible confusion may exist if investigators entered the time of documenting the hourly values rather than the time at which they were obtained.
HourlyValues.HVTime18 Original Investigators were requested to document hourly values every 2 hours (12 times per day) for all patients receiving ICP monitoring. The timeperiods were pre-specified (02:00-24:00); however, investigators may have entered values at different times and have then entered the time of obtaining hourly values; a possible confusion may exist if investigators entered the time of documenting the hourly values rather than the time at which they were obtained.
HourlyValues.HVTime2 Original Investigators were requested to document hourly values every 2 hours (12 times per day) for all patients receiving ICP monitoring. The timeperiods were pre-specified (02:00-24:00); however, investigators were allowed to enter another timepoint in this field.
HourlyValues.HVTime20 Original Investigators were requested to document hourly values every 2 hours (12 times per day) for all patients receiving ICP monitoring. The timeperiods were pre-specified (02:00-24:00); however, investigators may have entered values at different times and have then entered the time of obtaining hourly values; a possible confusion may exist if investigators entered the time of documenting the hourly values rather than the time at which they were obtained.
HourlyValues.HVTime22 Original Investigators were requested to document hourly values every 2 hours (12 times per day) for all patients receiving ICP monitoring. The timeperiods were pre-specified (02:00-24:00); however, investigators may have entered values at different times and have then entered the time of obtaining hourly values; a possible confusion may exist if investigators entered the time of documenting the hourly values rather than the time at which they were obtained.
HourlyValues.HVTime24 Original Investigators were requested to document hourly values every 2 hours (12 times per day) for all patients receiving ICP monitoring. The timeperiods were pre-specified (02:00-24:00); however, investigators may have entered values at different times and have then entered the time of obtaining hourly values; a possible confusion may exist if investigators entered the time of documenting the hourly values rather than the time at which they were obtained.
HourlyValues.HVTime4 Original Investigators were requested to document hourly values every 2 hours (12 times per day) for all patients receiving ICP monitoring. The timeperiods were pre-specified (02:00-24:00); however, investigators may have entered values at different times and have then entered the time of obtaining hourly values; a possible confusion may exist if investigators entered the time of documenting the hourly values rather than the time at which they were obtained.
HourlyValues.HVTime6 Original Investigators were requested to document hourly values every 2 hours (12 times per day) for all patients receiving ICP monitoring. The timeperiods were pre-specified (02:00-24:00); however, investigators may have entered values at different times and have then entered the time of obtaining hourly values; a possible confusion may exist if investigators entered the time of documenting the hourly values rather than the time at which they were obtained.
HourlyValues.HVTime8 Original Investigators were requested to document hourly values every 2 hours (12 times per day) for all patients receiving ICP monitoring. The timeperiods were pre-specified (02:00-24:00); however, investigators may have entered values at different times and have then entered the time of obtaining hourly values; a possible confusion may exist if investigators entered the time of documenting the hourly values rather than the time at which they were obtained.
Imaging.AcquisitionDate Meta Acquisition date and time for each scan of an entire session - retrieved from the DICOM header
Imaging.AcquisitionTime Acquisition date and time for each scan of an entire session - retrieved from the DICOM header
Imaging.AnyIntracranTraumaticAbnormality Meta This variable was assessed by a central review panel, according the TBI-Common Data Elements. This variable indicates whether any of the 12 following CDEs is present (Mass lesion, ExtraaxialHematoma, EpiduralHematoma, SubduralHematomaAcute, SubduralHematomaSubacuteChronic, SubduralCollectionMixedDensity, Contusion, TAI, traumaticSubarachnoidHemorrhage, IntraventricularHemorrhage, MidlineShift or CisternalCompression.
Imaging.BvalURL This variable is an URL towards the generated Bval file.
Imaging.BvecURL This variable is an URL towards the generated Bvec file.
Imaging.CisternalCompression Meta This variable was assessed by a central review panel, according the TBI-Common Data Elements. This variable indicates whether there is compression of one or more the basal cisterns (i.e. suprasellar, quadrigeminal, prepontine, ambient, cisterna magna). More descriptive information (location, compression vs. absence) can be found in the JSON files.
Imaging.Contusion Meta This variable was assessed by a central review panel, according the TBI-Common Data Elements. This variable indicates whether one or more contusions are present. More descriptive information (location, volume, number) and advanced information (e.g. hemorrhagic, non-hemorrhagic, intracerebral hemorrhage, etc.) can be found in the JSON files. Volume was estimated using the AxBxC/2 method. Edema was included in the measurements.
Imaging.CRFCTAngulation This variable describes if a CT scan is performed with or without angulation. There are three options: no angulation (volume scan), orbital-meatal line and other. There is a risk of different interpretation, since there was no definition.
Imaging.CRFCTManuf This variable describes the CT scans manufacturer.
Imaging.CRFCTMidlineShift CT parameters scored by the investigator: reflects if there was midline shift on the CT.
Imaging.CRFCTMidlineShiftMeasure CT parameters scored by the investigator: reflects the volume in mm if there was a midline shift on the CT Check also "Imaging.CRFCTMidlineShift"
Imaging.CRFCTMRIDate Date of Imaging captured in CRF
Imaging.CRFCTMRITime Time of imaging captured in CRF
Imaging.CRFCTReason This variable contains the main reason why a CT-scan, during hospital stay, was performed. One of following options: standard follow-up, post-operative control, clinical deterioration, (suspicion of) increasing ICP, lack of improvement, unknown, other (specified in CTMRI.CTReasonOther) The reason for making an early CT-scan/ER scan can be found in: CTMRI.CTERReason
Imaging.CRFCTScannerType This variable specifies the type of CT-scanner by the number of slices.
Imaging.CRFCTType This variable describes the type of CT scan that has been made. Multiple options can be selected from: Non-contrast CT, Contrast CT, CT Angiography, Perfusion CT.
Imaging.CRFForm Acute or follow up form in the e-CRF.
Imaging.CRFIcometrixImageId This variable combines data from CTMRI.IcometrixImageId and FollowUp.IcometrixImageId. Identifier generated for an imaging experiment when images are uploaded from site.
Imaging.CRFIcometrixPassedQA Reflects if images uploaded from site passed QA of icometix. This variable combines data from CTMRI.IcometrixPassedQA and FollowUp.IcometrixPassedQA.
Imaging.CRFInitialDataIcometrix Reflects if the imaging data was initially loaded from Icometrix into the e-CRF (if not, it means the data in the e-CRF was entered manually by the study nurse) This variable combines data from CTMRI.InitialDataIcometrix and FollowUp.InitialDataIcometrix.
Imaging.CRFMRIManuf This variable describes the MRI-scan manufacturer. This variable combines data from CTMRI.MRIManuf and FollowUp.MRIManuf
Imaging.CRFMRIReason This variable contains the main reason why an MRI was performed. This variable combines data from CTMRI.MRIReason and FollowUp.MRIReason
Imaging.CRFMRIReasonOther This variable contains the main reason why an MRI was performed, when in the variable "MRIReason", the option "other" was chosen. This is a text field. This variable combines data from CTMRI.MRIReasonOther and FollowUp.MRIReasonOther
Imaging.CRFMRIResultPreExistAbnorm This variable describes whether or not there are pre-existing abnormalities present on MRI scan (yes, no, unknown). Assessment by investigator and or physician. This variable combines data from CTMRI.MRIResultPreExistAbnorm and FollowUp.MRIResultPreExistAbnorm
Imaging.CRFMRIResultTraumaticAbnorm This variable describes whether or not there are traumatic abnormalities present on MRI scan (yes, no, unknown). Assessment by investigator and/or physician. This variable combines data from CTMRI.MRIResultTraumaticAbnorm and FollowUp.MRIResultTraumaticAbnorm
Imaging.CRFMRIScannerStrength This variable describes the MRI scanner strength. This is a text field. This variable combines data from CTMRI.MRIScannerStrength and FollowUp.MRIScannerStrength
Imaging.CRFMRISequences This variable describes the MRI sequence. Options are: T1, T2, FLAIR, DWI, GRE, SWI, DTI, MRSI, PWI, Other. Multiple options can be selected. This variable combines data from CTMRI.MRISequences and FollowUp.MRISequences
Imaging.CRFMRITraumAbnormASDH This variable describes whether or not there is an acute subdural hematoma present on MRI scan (yes, no, unknown). Assessment by investigator and/or physician. This variable combines data from CTMRI.MRITraumAbnormASDH and FollowUp.MRITraumAbnormASDH
Imaging.CRFMRITraumAbnormContusion This variable describes whether or not there is a contusion present on MRI scan (yes, no, unknown). Assessment by investigator and/or physician. This variable combines data from CTMRI.MRITraumAbnormContusion and FollowUp.MRITraumAbnormContusion
Imaging.CRFMRITraumAbnormDAI This variable describes whether or not there is DAI (diffuse axonal injury) present on MRI scan (yes, no, unknown). Assessment by investigator and/or physician. This variable combines data from CTMRI.MRITraumAbnormDAI and FollowUp.MRITraumAbnormDAI
Imaging.CRFMRITraumAbnormDAILesionLocBrainstem This variable describes whether or not there is a brain stem lesion present on MRI scan (yes, no, unknown). Assessment by investigator and/or physician. This variable combines data from CTMRI.MRITraumAbnormDAILesionLocBrainstem and FollowUp.MRITraumAbnormDAILesionLocBrainstem
Imaging.CRFMRITraumAbnormDAILesionLocCorpusCallosum This variable describes whether or not there is a corpus callosum lesion present on MRI scan (yes, no, unknown). Assessment by investigator and/or physician. This variable combines data from CTMRI.MRITraumAbnormDAILesionLocCorpusCallosum and FollowUp.MRITraumAbnormDAILesionLocCorpusCallosum
Imaging.CRFMRITraumAbnormDAILesionLocDiffuseWhiteMatter This variable describes whether or not there is a lesion in diffuse white matter present on MRI scan (yes, no, unknown). Assessment by investigator and/or physician. This variable combines data from CTMRI.MRITraumAbnormDAILesionLocDiffuseWhiteMatter and FollowUp.MRITraumAbnormDAILesionLocDiffuseWhiteMatter
Imaging.CRFMRITraumAbnormDAINumLesions This variable describes how many DAI lesions are present on MRI scan (1,2,3,4,>=5). Assessment by investigator and/or physician. This variable combines data from CTMRI.MRITraumAbnormDAINumLesions and FollowUp.MRITraumAbnormDAINumLesions
Imaging.CRFMRITraumAbnormEDH This variable describes whether or not there is an epidural hematoma present on MRI scan (yes, no, unknown). Assessment by investigator and/or physician. This variable combines data from CTMRI.MRITraumAbnormEDH and FollowUp.MRITraumAbnormEDH
Imaging.CRFMRIType This variable describes the type of MRI scan that has been made. Options are: MRI, MRA This variable combines data from CTMRI.MRIType and FollowUp.MRIType
Imaging.CRFTimePoint Derived Imaging.CRFTimepoint = CTMRI.Timepoint + FollowUp.Timepoint Imaging related data from CTMRI table and Followup is combined under Imaging table so that all data is available in a single place. We only combine the ones with a valid IcometrixImageId
Imaging.DicomHeaderURL Meta DICOM header can add more information to the Nifti image files. The DICOM header is the meta-data part of a DICOM file and is organized as a constant and standardized series of tags. This variable is a URL towards the header file.
Imaging.EpiduralHematoma Meta This variable was assessed by a central review panel, according the TBI-Common Data Elements. This variable indicates whether an epidural hematoma or multiple epidural hematomas are present. More descriptive information (location, volume, number) and advanced information (e.g. arterial versus venous) can be found in the JSON files. Note: Volume was estimated using the AxBxC/2 method. In the JSON files, "descriptive_volume" is the estimated volume of the lesion and can be used for analysis, "descriptive_length", "descriptive_width", "descriptive_max_thickness" are measurements that should not be used in any analysis.
Imaging.ExperimentDate Experiment Date and time for the entire scan session - retrieved from the DICOM header
Imaging.ExperimentId Meta S: Experiment id which is generated by the imaging repository (XNAT). B: Is a unique identifier. XNAT is the imaging platform used to collect the data. A: Format of this identifier looks like CTBI_E00000. R: ExperimentId is equal to all the scans within the same experiment: projects/PROJECT_ID/subjects/SUBJECT_ID/experiments/EXPT_ID/scans/SCAN_ID/files/file1.img
Imaging.ExperimentLabel Meta S: Experiment label created by the imaging repository. B: Usually looks like: "GUPI_CTx" or "GUPI_MRx" with x specifying the rank of the upload. This label is not a unique identifier. A: Label of the experiment. R: Users are allowed to edit. Label is only unique within one center.
Imaging.ExperimentTime Experiment Date and time for the entire scan session - retrieved from the DICOM header
Imaging.ExtraaxialHematoma Meta This variable was assessed by a central review panel, according the TBI-Common Data Elements. This variable indicates whether an extra-axial hematoma or multiple extra-axial hematomas are present. This term was mostly used for bleedings that were difficult to classify or for bleedings that were evacuated (i.e. after craniectomy). More descriptive information (location, volume, number) and advanced information (e.g. arterial versus venous) can be found in the JSON files. Note: Volume was estimated using the AxBxC/2 method. In the JSON files, "descriptive_volume" is the estimated volume of the lesion and can be used for analysis, "descriptive_length", "descriptive_width", "descriptive_max_thickness" are measurements that should not be used in any analysis.
Imaging.FisherClassification Derived S: A CT grading scale for traumatic Subarachnoid Hemorrhage B: Useful in predicting the occurrence and severity of cerebral vasospasm. Ranges from 1-4 (No tSAH, no IVH (1), no IVH, trace or moderate tSAH (can be in multiple locations) (2), No IVH, full tSAH (3), IVH (4) R: Only available for CT scans. For each patient, the FisherClassification can be found in the Imaging.LesionData variable. For CENTER-TBI, only the older version of Fisher was scored, not the newer "modified" version.
Imaging.Frames Meta B: Scan are acquired in dicom format. A: Number of dicom files that compose the scan.
Imaging.GreenCTGrade Derived A CT grading scale for traumatic Subarachnoid Hemorrhage (tSAH). Useful for outcome prediction. Ranges from 1-4, with a subdivision of 3 into "31", "32" and 4 into "41" and "42". (thin tSAH (1), thick tSAH (2), thin tSAH with mass lesion and no MLS (31), thin tSAH with mass lesion and MLS (32), thick tSAH with mass lesion and no MLS (41), thick tSAH with mass lesion and MLS (42). Only available for CT scans. For each patient, the GreenCTgrade can be found in the Imaging.LesionData variable. Could only be filled out when tSAH was present.
Imaging.HelsinkiCTScore Derived S: A general CT grading scale B: Useful for outcome prediction. Ranges from -3 to 14. Scoring is done as follows: subdural (+2), intracerebral hematoma (+2), epidural hematoma (-3), mass lesion size >25 cc (+2), IVH (+3), compressed cisterns (+1), obliterated cisterns (+5) R: Only available for CT scans. For each patient, the HelsinkiCTscore can be found in the Imaging.LesionData variable. Empty values for the HelsinkiCTscore stand for a normal CT scan! A score of 0 does not necessarily mean the patient had a normal CT. (e.g. epidural hematoma -3, + IVH = 3 = 0).
Imaging.IntraventricularHemorrhage Meta This variable was assessed by a central review panel, according the TBI-Common Data Elements. This variable indicates whether intraventricular blood is present. More descriptive information (location) can be found in the JSON files.
Imaging.LesionData Derived This variable contains ALL lesion information as assessed by central review. There are 23 CDEs that have been evaluated for each patient and 6 classifications that have been filled out. For 13 CDEs and all 6 classifications separate variables have been made available. (see "imaging." variables: SkullFracture, Mass lesion, ExtraaxialHematoma, EpiduralHematoma, SubduralHematomaAcute, SubduralHematomaSubacuteChronic, SubduralCollectionMixedDensity, Contusion, TAI, traumaticSubarachnoidHemorrhage, IntraventricularHemorrhage, MidlineShift, CisternalCompression. A derived variable was also created with AnyIntracranTraumaticAbnormality). These 13 CDEs only contain basic information (i.e. lesion is present, absent, indeterminate, uninterpretable, not interpreted).
Imaging.Manufacturer Meta S: Imaging scanner manufacturer. R: Tag (0008,0070) from dicom header available in Imaging.DicomHeaderURL
Imaging.MarshallCTClassification Derived A general CT grading scale. Useful for outcome prediction. Ranges from 1 to 6 in our dataset. (No visible pathology on CT (1), Cisterns present, MLS < 5 mm (2), Cisterns compressed or absent, MLS < 5 mm (3), MLS > 5 mm, no mass lesion > 25 cc (4), Evacuated mass lesion (5), Non-evacuated mass lesion (6)) Only available for CT scans. For each patient, the MarshallCTClassification can be found in a Imaging.LesionData variable. For the Marshall CT classification the admission scan was scored. (which is not necessarily the "worst").
Imaging.MassLesion Meta This variable was assessed by a central review panel, according the TBI-Common Data Elements. This variable indicates whether a mass lesion is present. "Mass Lesion" in this case was defined as a total brain lesion volume > 25 cc. Note that this can mean that there is at least one large lesion or multiple co-existing lesions (contusions, subdural hematomas, etc.) that add up to > 25 cc. More information can be found in the JSON files.
Imaging.MidlineShift Meta This variable was assessed by a central review panel, according the TBI-Common Data Elements. This variable indicates whether a midline shift of > 5 mm is present. More descriptive information (direction) can be found in the JSON files.
Imaging.MorrisMarshallClassification Derived S: A CT grading scale for traumatic Subarachnoid Hemorrhage (tSAH) B: Useful for outcome prediction. Ranges from 0-4. (no tSAH (0), trace or moderate tSAH in one location (basal, cortical or tentorial) (1), one location full, or 2 not full (2), two locations full (3), 3 locations or more (4)) R: Only available for CT scans. For each patient, the MorrisMarshallClassification can be found in a Imaging.LesionData variable.
Imaging.NiftiURL Meta S: Nifti files are converted from original dicom files. B: Nifti is an imaging format.(Neuroimaging Informatics Technology Initiative file format) A: This variable is an URL towards the generated nifti file. R: Open source tool to convert dicom to nifti https://github.com/icometrix/dicom2nifti
Imaging.QCResultsURL Meta S: A json file containing MR quality measures. B: All different quality measures that have been applied are being collected in one json file. The comprises at least a protocol check, snr, cnr, head coverage, GM/WM, FA/MD, tensor residuals, ... A: Url to the .json file
Imaging.ReportStatus Derived S: Visual inspection remark B: All MR images have been visually inspected and labeled as approved, rejected or approved with remark. The remark can be found in Imaging.ReportStatusComments R: Imaging.QCResultsURL is being used during this visual inspection. This is the prefered status of the quality of the images.
Imaging.ReportStatusComments Derived S: Comment on the report status B: All MR images have been visually inspected and labeled as approved, rejected or approved with remark. This variable contains the motivation if the status is rejected or approved with remark.
Imaging.RotterdamCTScore Derived S: A general CT grading scale B: Useful for outcome prediction. Ranges from 1 to 6 in our dataset. Scoring was as follows: IVH or tSAH (+1), Epidural Mass not present (+1), MLS > 5 mm (+1), cisterns compressed (+1), cisterns absent (+1), SUM SCORE = +1 R: Only available for CT scans. For each patient, the RotterdamCTscore can be found in the Imaging.LesionData variable.
Imaging.ScanDetection Derived S: Triaging variable for the usablity of a CT scan B: Since all clinical CT scans (head, neck, spine, ...) are uploaded, it is not always clear which scans are usable an which not. In order to know what scans are usable, a variable is defined. This variable gives as an output: UNUSABLE SCANS / USABLE SCANS / DOUBTFULL. R: This triaging is done by computer algorithms and is not 100% water tight.
Imaging.ScanLabel Meta S: Scan label is a specific identifier for a scan. A: Scan label contains 3 parts: Imaging.ExperimentID Imaging.ExperimentLabel (0020,0011) Series Number (from dicom header) Format: Imaging.ExperimentID_Imaging.ExperimentLabel_SeriesNumber "
Imaging.Scanner Meta Imaging scanner This information is available from the Imaging.DicomHeaderURL
Imaging.ScanNotes Meta S: Free text remarks from dcm2nii conversion B: This free text variable is used for internal purpose A: R: opensource dcm2nii converter available https://github.com/icometrix/dicom2nifti
Imaging.ScanQuality Derived S: This variable is specified by the one who uploaded the images to the imaging repository B: Possible values are usable, questionable, unusable A: Quality of the scan R: Might be very arbitrary and therefor preferable use Imaging.QCResultsURL data and Imaging.ReportStatus as quality reference.
Imaging.ScanType Meta S: MR Mapping for series description B: Since all centers use different series description, a mapping for T2, T1, FLAIR, T2*, DTI and rs-fMRI is provided. R: For CT, ScanType and Series Description should be the same.
Imaging.SeriesDescription Meta S: Scan Series description retrieved from DICOM header A: Serie Name Given by the image acquisition center. R: DICOM Tag (0008,103E) Series Description
Imaging.SkullFracture Meta This variable was assessed by a central review panel, according the TBI-Common Data Elements. This variable indicates whether a skull fracture or multiple skull fractures are present. More descriptive information (location, number) and advanced information (morphology: e.g. depressed, compound, etc.) can be found in the JSON files.
Imaging.SnapshotURL Derived S: Mid-slice snapshot from three planes: axial, sagittal and coronal. B: In order to have a quick view on the data, a snapshot of the mid-slice in 3 planes is provided. A: Url to .png screenshot of generated nifti images. R: Screenshot are defaced.
Imaging.SubduralCollectionMixedDensity Meta This variable was assessed by a central review panel, according the TBI-Common Data Elements. This variable indicates whether one or multiple subdural collections/mixed density hematomas are present. More descriptive information (location, volume, number) and advanced information (e.g. isodensity, hypodensity, acute on chronic, chronic recurrent etc.) can be found in the JSON files. Volume was estimated using the AxBxC/2 method. Note: cfr. epidural and subdural hematoms regarding volumes. Note: In the JSON files length, width and depth of lesions can not be used as metrics in any analysis! Only "descriptive volume" is a valid metric (in cc)
Imaging.SubduralHematomaAcute Meta This variable was assessed by a central review panel, according the TBI-Common Data Elements. This variable indicates whether an acute subdural hematoma or multiple acute subdural hematomas are present. More descriptive information (location, volume, number) and advanced information (homogeneous versus heterogeneous) can be found in the JSON files.Volume was estimated using the AxBxC/2 method, however, small traces of acute subdural blood on the tentorium or interhemispheric were not measured. Note: cfr. epidural: only "descriptive_volume" can be used for analysis. Note: In the JSON files length, width and depth of lesions can not be used as metrics in any analysis! Only "descriptive volume" is a valid metric (in cc)
Imaging.SubduralHematomaSubacuteChronic Meta This variable was assessed by a central review panel, according the TBI-Common Data Elements. This variable indicates whether one or multiple subacute/chronic subdural hematoma(s) are present. More descriptive information (location, volume, number) can be found in the JSON files.Note: Volume was estimated using the AxBxC/2 method. Note: this variable is best considered together with the "SubduralCollectionMixedDensity" variable, as the central reviewer did not have information to time of injury. Many subacute/chronic subdurals were therefore categorised as "mixed density". Note: cfr. epidural and acute subdural hematoma regarding volumes. Note: In the JSON files length, width and depth of lesions can not be used as metrics in any analysis! Only "descriptive volume" is a valid metric (in cc)
Imaging.SubjectGroup Meta S: Subject stratum B: Possible options are: ER, ADMISSION, ICU
Imaging.TAI Meta This variable was assessed by a central review panel, according the TBI-Common Data Elements. This variable indicates whether axonal injury is present. More descriptive information (location, TAI versus DAI) can be found in the JSON files. Note: be aware of the modality you are interested in (i.e. CT or MRI).
Imaging.ThumbnailURL Derived S: Screenshot are automatically generated. B: Thumbnails are reduced-size versions of pictures. A: Url to .png screenshot of generated nifti images. R: You can find higher resolution image at the URL provided by Imaging.SnaphshotURL. Screenshot are defaced.
Imaging.Timepoint Meta S: Timepoint of the scan acquisition B: For CT scans, possible options are: CT Early, CT Followup, CT Post-op For MR scans, possible options are: MR Early, MR 2 weeks, MR 3 months, MR 6 months, MR 12 months, MR 24 months A: Timepoint of the scan acquisition. R: Date and Time of the experiment is available in Imaging.ExperimentDateTime In order to have the intitial CT reports, download this variable in Neurobot, together with Subject.GUPI, Imaging.ExperimentId and your variables of interest. See steps Imaging.ExperimentId variable.
Imaging.TraumaticSubarachnoidHemorrhage Meta This variable was assessed by a central review panel, according the TBI-Common Data Elements. This variable indicates whether traumatic subarachnoid blood is present. More descriptive information (location and amount (e.g. trace, moderate, severe)) can be found in the JSON files. * Location can be: cortical, basal, interhemispheric or tentorial.
Imaging.WindowDetectionComment Derived Available in case Imaging.WindowDetectionQuality = Window Uncertainty. Imaging.WindowDetection specify if the images are Bone Window, Brain Window or if there is Window Uncertainty. Only available for CT scans.
Imaging.WindowDetectionQuality Derived S: Automated Detection for bone versus brain. B: Possible options: Bone Window, Brain Window, Window Uncertainty R: Only available for CT scans. No brain window scans should be classified as bone window.
Imaging.XsiType Meta S: Type of imaging (CT/MR) A: Assess if the scan is CT or MR R: Possible values 'xnat:mrSessionData' and 'xnat:ctSessionData'
InjuryHx.AbdomenPelvicContentsAIS 0 == 0 No Injury
1 == 1 Minor
2 == 2 Moderate
3 == 3 Serious
4 == 4 Severe
5 == 5 Critical
6 == 6 Unsurvivable
AIS score for the Abdomen/Pelvic Contents In the original AIS classification of injury severity, the grading is from 1 (minor) to 6 (unsurvivable). We added a score of 0 to designate absence of injuries.
InjuryHx.AbdomenPelvicContentsDesc 1 == Spleen rupture
2 == Liver rupture
3 == Perforating abdominal injury
4 == Kidney contusion
5 == Retroperitoneal hematoma
99 == Other
Injury description related to the AIS/ISS score for the Abdomen/Pelvic Contents
InjuryHx.AbdomenPelvicContentsISS Calculated ISS score for the Abdomen/Pelvic Contents
InjuryHx.AbdomenPelvicLumbarRegionAIS AIS score for the Abdomen/Pelvic Lumbar region In the original AIS classification of injury severity, the grading is from 1 (minor) to 6 (unsurvivable). We added a score of 0 to designate absence of injuries.
InjuryHx.ACEFocalNeuroDeficit 0 == No
1 == Yes
88 == Unknown
On the neurological assessment at presentation overall rating was recorded on Focal neurological deficit (eg paresis or dysphasia)
InjuryHx.ACEFocalNeuroDeficitDysphasia 0 == No
1 == Yes
88 == Unknown
On the neurological assessment at presentation overall rating was recorded on Focal neurological deficit (eg paresis or dysphasia). If this was rate as "yes", details were recorded on whether it was paresis or dysphasia.
InjuryHx.ACEFocalNeuroDeficitOther On the neurological assessment at presentation overall rating was recorded on Focal neurological deficit (eg paresis or dysphasia) If this was rate as "yes", details were recorded on whether it was paresis or dysphasia or other.
InjuryHx.ACEFocalNeuroDeficitOtherTxt On the neurological assessment at presentation overall rating was recorded on Focal neurological deficit (eg paresis or dysphasia) If this was rate as "yes", details were recorded on whether it was paresis or dysphasia or other, and for other it was specified which one.
InjuryHx.ACEFocalNeuroDeficitParesis 0 == No
1 == Yes
88 == Unknown
On the neurological assessment at presentation overall rating was recorded on Focal neurological deficit (eg paresis or dysphasia) If this was rate as "yes", details were recorded on whether it was paresis or dysphasia.
InjuryHx.ACEOverallRating 1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
On the neurological assessment at presentation overall rating was recorded on "How different the person is acting compared to his/her usual self" The rating was on a scale from 1 (normal) to 6 (very different).
InjuryHx.ACEOverallRatingUnknown On the neurological assessment at presentation overall rating was recorded on "How different the person is acting compared to his/her usual self" This variable reflects if the rating was "unknown".
InjuryHx.ACERatedBy 1 == Proxy
2 == Subject
3 == Both proxy and subject
4 == Not done
On the neurological assessment at presentation overall rating was recorded on "How different the person is acting compared to his/her usual self" This variable reflects by whom the rating was performed.
InjuryHx.AlcPriorUseInd 0 == No
1 == Yes
88 == Unknown
On presentation the behavioral history of the patient was recorded. This reflects his past use of alcoholic beverages (beer, wine, spirits).
InjuryHx.AlcUseDur Original On presentation the behavioral history of the patient was recorded. This reflects the number of years of alcohol use, if past use of alcoholic beverages (beer, wine, spirits) was 'yes'.
InjuryHx.AlcUseLstMoDaysDrankNum 0 == No
1 == Yes
88 == Unknown
On presentation the behavioral history of the patient was recorded. This reflects his use in the past three months of alcoholic beverages (beer, wine, spirits) (>2/day)
InjuryHx.AUDITCAlcDrnkTypclDayNumScore 1 == 1-2
2 == 3-4
3 == 5-6
4 == 7-9
5 == 10 or more
88 == Unknown
On presentation the behavioral history of the patient was recorded. In case of past use of alcoholic beverages (beer, wine, spirits), this reflects the alcohol frequency: average number of drinks on a "drinking" day
InjuryHx.AUDITCDrnkContainAlcFreqScore 0 == Never
1 == Monthly or less
2 == 2-4 times a month
3 == 2-3 times a week
4 == 4 or more times a week
88 == Unknown
Detailed questions on the use of alcohol are derived from the first 3 questions of the "AUDIT" questionnaire, a screening tool developed by the World Health Organization (WHO) to assess alcohol consumption, drinking behaviors, and alcohol-related problems. The same questions are asked post-injury during full follow-up assessments (including cognitive testing.) This reflects the frequency of having a drink containing alcohol.
InjuryHx.AUDITCMoreThan6AlcDrnkFreqScore 0 == Never
1 == Monthly or less (incorrect please correct)
2 == 2-4 times a month (incorrect please correct)
3 == 2-3 times a week (incorrect please correct)
4 == 4 or more times a week (incorrect please correct)
5 == Less than monthly
6 == Monthly
7 == Weekly
8 == Daily or almost daily
88 == Unknown
Detailed questions on the use of alcohol are derived from the first 3 questions of the "AUDIT" questionnaire, a screening tool developed by the World Health Organization (WHO) to assess alcohol consumption, drinking behaviors, and alcohol-related problems. The same questions are asked post-injury during full follow-up assessments (including cognitive testing.) This reflects the frequency of having six or more drinks on one occasion.
InjuryHx.BaselineGCSMostReliableAssessmentCondition 0 == No sedation/paralysis
1 == Under sedation
3 == After stopping sedation
4 == After pharmacological reversal
A baseline risk assessment was performed at the hospital (ER). This reflects the Conditions of assessment for the Most reliable Motor Score for risk assessment.
InjuryHx.BaselineGCSMostReliableAssessmentTime 1 == Admission
2 == Post-stabilization
3 == First hospital
4 == Scene of accident
5 == Other
A baseline risk assessment was performed at the hospital (ER). This reflects the Time of assessment for the Most reliable Motor Score for risk assessment.
InjuryHx.BaselineGCSMostReliableMotorScore Original A baseline risk assessment was performed at the hospital (ER). This reflects the Most reliable baseline Motor score of the GCS as given by sites - for use in prognostic models.
InjuryHx.BaselineGOS6MoDateOfPrognosticEstimate At ER discharge, physician estimate of six month outcome was recorded as a baseline risk assessment: "Given all current available information, what is, in your subjective opinion, the most likely 6-month outcome of this patient? To be based upon information on discharge ER or admission to hospital/ICU". This reflects the Date of prognostic estimate
InjuryHx.BaselineGOS6MoExpectedDeathRisk Original At ER discharge, physician estimate of six month outcome was recorded as a baseline risk assessment: "Given all current available information, what is, in your subjective opinion, the most likely 6-month outcome of this patient? To be based upon information on discharge ER or admission to hospital/ICU". This reflects the Risk of death in %
InjuryHx.BaselineGOS6MoExpectedOutcome GR == GR - Good Recovery
MD == MD - Moderate Disability
SD == SD - Severe Disability
V == V - Vegetative State
D == D - Death
At ER discharge, physician estimate of six month outcome was recorded as a baseline risk assessment: "Given all current available information, what is, in your subjective opinion, the most likely 6-month outcome of this patient? To be based upon information on discharge ER or admission to hospital/ICU". This reflects the Expected outcome (GOS)
InjuryHx.BaselineGOS6MoUnfavourableOutcomeRisk Original At ER discharge, physician estimate of six month outcome was recorded as a baseline risk assessment: "Given all current available information, what is, in your subjective opinion, the most likely 6-month outcome of this patient? To be based upon information on discharge ER or admission to hospital/ICU". This reflects the Risk of unfavorable outcome (D, VS, SD) in %
InjuryHx.BaselinePhysEstOf6MoOutcomePhysicianQual 1 == Resident
2 == Junior staff (< 5 years)
3 == Senior staff (>= 5 years)
4 == Head of department
At ER discharge, physician estimate of six month outcome was recorded as a baseline risk assessment: "Given all current available information, what is, in your subjective opinion, the most likely 6-month outcome of this patient? To be based upon information on discharge ER or admission to hospital/ICU". This reflects the qualification of the physician who provided prognostic estimate on ER discharge/admission to hospital/ICU
InjuryHx.BaselinePhysEstOf6MoOutcomePhysicianType 1 == ER Physician
2 == Intensive Care
3 == Neurology
4 == Neurosurgery
5 == Traumatology
88 == Unknown
At ER discharge, physician estimate of six month outcome was recorded as a baseline risk assessment: "Given all current available information, what is, in your subjective opinion, the most likely 6-month outcome of this patient? To be based upon information on discharge ER or admission to hospital/ICU". This reflects the type of the physician who provided prognostic estimate on ER discharge/admission to hospital/ICU
InjuryHx.BestOfAbdomenPelvicLumbarISS Calculated AbdomenPelvicLumbar region (Highest AIS of the region)^2 compare AbdomenPelvicContentsAIS, LumbarSpineAIS. This score is taken forward for ISS calculation
InjuryHx.BestOfChestSpineISS Calculated (highest AIS of the region)^2 Compare ThoraxChestAIS, ThoracicSpineAIS and select the highest for ISS calculation
InjuryHx.BestOfExternaISS Calculated External region (ExternaAIS)^2 select the highest external AIS severity code for ISS calculation.
InjuryHx.BestOfExtremitiesISS Calculated Extremities region (Highest AIS of the region)^2 compare UpperExtremitiesAIS, LowerExtremitiesAIS, PelvicGirdleAIS select the highest for ISS calculation
InjuryHx.BestOfFaceISS Calculated Face region (FaceAIS)^2 select the highest facial injury for ISS calculation
InjuryHx.BestOfHeadBrainCervicalISS Calculated HeadBrainCervical region (Highest AIS of the region)^2 Compare HeadNeckAIS, InjuryHx.BrainInjuryAIS, CervicalSpineAIS select the highest scoring injury in any of these 3 areas for ISS calculation
InjuryHx.BrainInjuryAIS Original 0 == 0 No Injury
1 == 1 Minor
2 == 2 Moderate
3 == 3 Serious
4 == 4 Severe
5 == 5 Critical
6 == 6 Unsurvivable
AIS score for the Brain Injury In the original AIS classification of injury severity, the grading is from 1 (minor) to 6 (unsurvivable). We added a score of 0 to designate absence of injuries.
InjuryHx.BrainInjuryDesc 1 == Concussion
2 == Contusions
3 == EDH
4 == Diffuse Injury
5 == ASDH
99 == Other
Injury description related to the AIS/ISS score for the Brain Injury. Injury description is coded by drop-down menus for each body region
InjuryHx.CannabisCurrentUse 0 == No
1 == Yes
88 == Unknown
On presentation the behavioral history of the patient was recorded. This reflects the use in the past three months of Cannabis (marijuana, pot, grass, hash, etc.)
InjuryHx.CannabisPriorUse 0 == No
1 == Yes
88 == Unknown
On presentation the behavioral history of the patient was recorded. This reflects his past use of Cannabis (marijuana, pot, grass, hash, etc.)
InjuryHx.CannabisPriorUseDuration Original On presentation the behavioral history of the patient was recorded. This reflects the number of years of past use of Cannabis if applicable.
InjuryHx.CervicalSpineAIS Original 0 == 0 No Injury
1 == 1 Minor
2 == 2 Moderate
3 == 3 Serious
4 == 4 Severe
5 == 5 Critical
6 == 6 Unsurvivable
AIS score for Cervical Spine region. In the original AIS classification of injury severity, the grading is from 1 (minor) to 6 (unsurvivable). We added a score of 0 to designate absence of injuries.
InjuryHx.CervicalSpineDesc 1 == Fracture
2 == Dislocation
99 == Other
Injury description related to the AIS/ISS score for the Cervical Spine region.
InjuryHx.DispER 1 == Discharge home
2 == Discharge other facility
3 == Hospital admission--Ward
4 == Hospital admission--Intermediate/high care unit
5 == Hospital admission--ICU
6 == Hospital admission--OR for immediate surgical procedure
7 == Death
8 == Hospital admission--Other (e.g. observation unit)
88 == Unknown
Destination of the patient at ER discharge.
InjuryHx.DrgSubIllctCurntUseInd 0 == No
1 == Yes
88 == Unknown
On presentation the behavioral history of the patient was recorded. This reflects the use in the past three months of Other recreational drugs (than Cannabis)
InjuryHx.DrgSubIllctUseCatOther On presentation the behavioral history of the patient was recorded. This reflects his past use of which type of drugs.
InjuryHx.DrgSubIllctUseDur Original On presentation the behavioral history of the patient was recorded. This reflects the number of years of his past use of recreational drugs, if applicable.
InjuryHx.DrgSubPriorIllctUseInd 0 == No
1 == Yes
88 == Unknown
On presentation the behavioral history of the patient was recorded. This reflects his past use of Other recreational drugs (other than Cannabis)
InjuryHx.DrugIllicitCurrentUseOther On presentation the behavioral history of the patient was recorded. This reflects the use in the past three months of which type of drugs
InjuryHx.EDAirway 1 == No specific treatment
2 == Supplemental oxygen (via nasal tube or mask)
3 == Adjunctive airway (eg. Mayo tube)
4 == Temporary support with bag, valve, mask (eg.ambubag)
5 == Intubation
6 == Mechanical ventilation
88 == Unknown
Records treatment performed in the ER/on admission with regard to Airways. Pre-hospital inteventions are documented at: InjuryHx.PresEmergencyCare
InjuryHx.EDArrDBP Original Reflects the vital signs at ER arrival: BP (mmHg) --> Diastolic
InjuryHx.EDArrHR Original Reflects the vital signs at ER arrival: Heart rate --> Beats per min.
InjuryHx.EDArrivalAirway 1 == Clear
2 == Obstructed
3 == Adjunctive Airway
4 == Intubated
88 == Unknown
The ABC status on arrival documents the status of Airway, Breathing and Circulation upon arrival to Study Hospital (ER); In addition, administration of supplemental oxygen and spinal immobilization is documented.
InjuryHx.EDArrivalArtpCO2kPa Original Reflects the vital signs at ER arrival: Arterial pCO2 --> kPa
InjuryHx.EDArrivalArtpCO2mmhg Original Reflects the vital signs at ER arrival: Arterial pCO2 --> mmHg
InjuryHx.EDArrivalArtpCO2unit 1 == kPa
2 == mmHg
Reflects the vital signs at ER arrival: Unit used for Arterial pCO2
InjuryHx.EDArrivalArtpCO2Unknown Reflects the vital signs at ER arrival: Arterial pCO2 --> Unknown
InjuryHx.EDArrivalArtpO2kPa Original Reflects the vital signs at ER arrival: Arterial pO2 --> kPa
InjuryHx.EDArrivalArtpO2mmhg Original Reflects the vital signs at ER arrival: Arterial pO2 --> mmHg
InjuryHx.EDArrivalArtpO2unit 1 == kPa
2 == mmHg
Reflects the vital signs at ER arrival: Unit used for Arterial pO2
InjuryHx.EDArrivalArtpO2Unknown Reflects the vital signs at ER arrival: Arterial pO2 --> Unknown
InjuryHx.EDArrivalBaseExcess Reflects the vital signs at ER arrival: Base excess --> mEq/l
InjuryHx.EDArrivalBaseExcessUnit 1 == mEq/l
99 == Other
Reflects the vital signs at ER arrival: the unit used for Base excess
InjuryHx.EDArrivalBaseExcessUnitSpecify Reflects the vital signs at ER arrival: specifies if another unit was used than the standard unit for Base excess
InjuryHx.EDArrivalBaseExcessUnknown Reflects the vital signs at ER arrival: Base excess --> Unknown
InjuryHx.EDArrivalBloodGasDone 0 == No
1 == Yes
Reflects the vital signs at ER arrival: reflects if First arterial blood gas was done Arterial blood gas analysis is not required for all subjects. Performed on clinical indication; will generally be restricted to subjects with more severe injuries
InjuryHx.EDArrivalBloodPressureUnknown 88 == Unknown Reflects the vital signs at ER arrival: BP (mmHg) --> Unknown
InjuryHx.EDArrivalBMI Calculated BMI using height in inches (EDArrivalHeightInches) and weight in pounds (EDArrivalBodyWeightLbs) BMI=((weight/(height*height)) * 704.5469
InjuryHx.EDArrivalBMIKgCm Calculated BMI using height in cm (EDArrivalHeightCm) and weight (EDArrivalBodyWeightKg) BMI= (Weight/(Height*Height))) * 10000
InjuryHx.EDArrivalBodyWeightKg Original Body weight in KG at ER arrival
InjuryHx.EDArrivalBodyWeightLbs Original Body weight in LBS at ER arrival
InjuryHx.EDArrivalBodyWeightMeasured 1 == Estimated
2 == Self reported
3 == Measured
4 == Proxy reported
88 == Unknown
Provides an indication of accuracy of reported body weight at ER arrival
InjuryHx.EDArrivalBodyWeightUnit Original 1 == kg
2 == lbs
Unit used for Body weight at ER arrival
InjuryHx.EDArrivalBreathing 1 == Spontaneous, adequate
2 == Spontaneous, insufficient
3 == Manual support with bag, valve, mask
4 == Mechanical ventilation
88 == Unknown
The ABC status on arrival documents the status of Airway, Breathing and Circulation upon arrival to Study Hospital (ER); In addition, administration of supplemental oxygen and spinal immobilization is documented.
InjuryHx.EDArrivalCirculation 0 == No specific therapy
1 == IV Fluids
2 == Vasopressors
3 == CPR
88 == Unknown
The ABC status on arrival documents the status of Airway, Breathing and Circulation upon arrival to Study Hospital (ER); In addition, administration of supplemental oxygen and spinal immobilization is documented.
InjuryHx.EDArrivalFiO2 Original Reflects the vital signs at ER arrival: FiO2 (in %) Information on FiO2 (Fraction of Inspired oxygen) at time of arterial blood gas sampling is requested in order to be able to calculate PaO2/FiO2 as measure of severity of hypoxaemia; dependent on altitude; at sea-level, normal values are > 500 mmHg
InjuryHx.EDArrivalFiO2Unknown Reflects the vital signs at ER arrival: FiO2 (in %) = unknown
InjuryHx.EDArrivalHeartRateUnknown Reflects the vital signs at ER arrival: Heart rate --> Unknown
InjuryHx.EDArrivalHeightCm Original Reflects Height in cm at ER arrival
InjuryHx.EDArrivalHeightInches Original Reflects Height in inches at ER arrival
InjuryHx.EDArrivalHeightMeasured 1 == Estimated
2 == Self reported
3 == Measured
4 == Proxy reported
88 == Unknown
Provides an indication of accuracy of reported height at ER arrival
InjuryHx.EDArrivalHeightUnit Original 1 == cm
2 == inch
Reflects unit used for Height at arrival
InjuryHx.EDArrivalLactate Original Reflects the vital signs at ER arrival: Lactate --> mEq/l
InjuryHx.EDArrivalLactateUnit Original 1 == mEq/l
99 == Other
Reflects if for "lactate" as vital signs at ER arrival another unit was used than the standard.
InjuryHx.EDArrivalLactateUnitSpecify Original Reflects the vital signs at ER arrival: Specifies for Lactate the unit used if another unit than the standard was used
InjuryHx.EDArrivalLactateUnknown Reflects the vital signs at ER arrival: Lactate --> Unknown
InjuryHx.EDArrivalOxygenSatUnknown Reflects the vital signs at ER arrival: Oxygen saturation --> Unknown
InjuryHx.EDArrivalpH Original Reflects the vital signs at ER arrival: pH
InjuryHx.EDArrivalpHUnknown Reflects the vital signs at ER arrival: pH --> Unknown
InjuryHx.EDArrivalRespRateUnknown 1 == Spontaneous
2 == Ventilated
88 == Unknown
Reflects the vital signs at ER arrival: Respiratory rate --> Unknown
InjuryHx.EDArrivalSpinalImmob 0 == No
1 == Yes
88 == Unknown
The ABC status on arrival documents the status of Airway, Breathing and Circulation upon arrival to Study Hospital (ER); In addition, administration of supplemental oxygen and spinal immobilization is documented.
InjuryHx.EDArrivalSupplementalOxygen 0 == No
1 == Yes
88 == Unknown
The ABC status on arrival documents the status of Airway, Breathing and Circulation upon arrival to Study Hospital (ER); In addition, administration of supplemental oxygen and spinal immobilization is documented.
InjuryHx.EDArrivalTemperatureUnknown The ABC status on arrival documents the status of Airway, Breathing and Circulation upon arrival to Study Hospital (ER); In addition, administration of supplemental oxygen and spinal immobilization is documented.
InjuryHx.EDArrPupilLftEyeMeasr Original 1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
7 == 7
8 == 8
9 == 9
10 == 10
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This reflects the size of the left eye pupil for the assessment at Arrival to ER of the study hospital.
InjuryHx.EDArrPupilLftEyeMeasrUnkUnt 66 == Untestable
88 == Unknown
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This reflects if GCS was Untestable/Unknown for the assessment at Arrival to ER of the study hospital.
InjuryHx.EDArrPupilReactivityLghtLftEyeReslt 1 == + (Brisk)
2 == + (Sluggish)
3 == - (Negative)
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This reflects the reactivity of the left eye pupil for the assessment at Arrival to ER of the study hospital.
InjuryHx.EDArrPupilReactivityLghtRtEyeReslt 1 == + (Brisk)
2 == + (Sluggish)
3 == - (Negative)
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This reflects the reactivity of the right eye pupil for the assessment at Arrival to ER of the study hospital.
InjuryHx.EDArrPupilRtEyeMeasr Original 1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
7 == 7
8 == 8
9 == 9
10 == 10
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This reflects the size of the right eye pupil for the assessment at Arrival to ER of the study hospital.
InjuryHx.EDArrPupilRtEyeMeasrUnkUnt 66 == Untestable
88 == Unknown
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This reflects if GCS was Untestable/Unknown for the assessment at Arrival to ER of the study hospital.
InjuryHx.EDArrPupilSymmetry 1 == Equal
2 == Unequal R>L
3 == Unequal L>R
66 == Untestable
88 == Unknown
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This reflects the Pupil symmetry for the assessment at Arrival to ER of the study hospital.
InjuryHx.EDArrRespRate Original Reflects the vital signs at ER arrival: Respiratory rate --> cycles per min
InjuryHx.EDArrSBP Original Reflects the vital signs at ER arrival: BP (mmHg) --> Systolic
InjuryHx.EDArrSpO2 Original Reflects the vital signs at ER arrival: Oxygen saturation (in %)
InjuryHx.EDArrTempCelsius Original Reflects the vital signs at ER arrival: Temperature --> Celcius
InjuryHx.EDArrTempFahrenheit Original Reflects the vital signs at ER arrival: Temperature --> Fahrenheit
InjuryHx.EDArrTempUnit 1 == C
2 == F
Reflects the unit used for temperature measurement as vital signs at ER arrival
InjuryHx.EDBloodGasConditions Original 1 == Pre-intubation, room air
2 == Pre-intubation, +O2
3 == Post-intubation, not ventilated
4 == Post-intubation, ventilated
Reflects the vital signs at ER arrival: Conditions for First arterial blood gas done (if applicable)
InjuryHx.EDBloodGasDate Original Reflects the vital signs at ER arrival: date for First arterial blood gas done (if applicable)
InjuryHx.EDBloodGasTime Original Reflects the vital signs at ER arrival: time for First arterial blood gas done (if applicable)
InjuryHx.EDBloodTrans Original 0 == No
1 == Yes
88 == Unknown
Reflects of blood transfusion was done in the ER of the study hospital
InjuryHx.EDCircCPR Original Records treatment performed in the ER/on admission with regard to Circulation: CPR. Pre-hospital inteventions are documented at: InjuryHx.PresEmergencyCare
InjuryHx.EDCircIV Original Records treatment performed in the ER/on admission with regard to Circulation: IV fluids. Pre-hospital inteventions are documented at: InjuryHx.PresEmergencyCare
InjuryHx.EDCircNone Original Records treatment performed in the ER/on admission with regard to Circulation: no specific treatment Pre-hospital inteventions are documented at: InjuryHx.PresCirculationTreatmentNone
InjuryHx.EDCircUnknown Original Records treatment performed in the ER/on admission with regard to Circulation: unknown. Pre-hospital inteventions are documented at: InjuryHx.PresEmergencyCare
InjuryHx.EDCircVaso Original Records treatment performed in the ER/on admission with regard to Circulation: vasopressors. Pre-hospital inteventions are documented at: InjuryHx.PresEmergencyCare
InjuryHx.EDCoagulopathyType1 Original 1 == Packed red blood cell concentrates (pRBCs)
2 == Fresh whole blood
3 == Fresh frozen plasma (FFP)
4 == Freeze dried plasma / lypholized plasma
5 == Platelet concentrates
6 == PCC (prothrombin complex concentrates)
7 == Fibrinogen concentrate
8 == Albumin
9 == Recombinant factor FVIIa
10 == Tranexamic acid (TXA)
11 == Cryoprecipitate
12 == Desmopression (DDAVP)
13 == Factor XIII
14 == Calcium
15 == Vitamin K (Konakion)
Reflects the type of transfusion or coagulopathy treatment given in the ER of the study hospital (if applicable)
InjuryHx.EDCoagulopathyType2 Original 1 == Packed red blood cell concentrates (pRBCs)
2 == Fresh whole blood
3 == Fresh frozen plasma (FFP)
4 == Freeze dried plasma / lypholized plasma
5 == Platelet concentrates
6 == PCC (prothrombin complex concentrates)
7 == Fibrinogen concentrate
8 == Albumin
9 == Recombinant factor FVIIa
10 == Tranexamic acid (TXA)
11 == Cryoprecipitate
12 == Desmopression (DDAVP)
13 == Factor XIII
14 == Calcium
15 == Vitamin K (Konakion)
Reflects the type of transfusion or coagulopathy treatment given in the ER of the study hospital (if applicable)
InjuryHx.EDCoagulopathyType3 Original 1 == Packed red blood cell concentrates (pRBCs)
2 == Fresh whole blood
3 == Fresh frozen plasma (FFP)
4 == Freeze dried plasma / lypholized plasma
5 == Platelet concentrates
6 == PCC (prothrombin complex concentrates)
7 == Fibrinogen concentrate
8 == Albumin
9 == Recombinant factor FVIIa
10 == Tranexamic acid (TXA)
11 == Cryoprecipitate
12 == Desmopression (DDAVP)
13 == Factor XIII
14 == Calcium
15 == Vitamin K (Konakion)
Reflects the type of transfusion or coagulopathy treatment given in the ER of the study hospital (if applicable)
InjuryHx.EDCoagulopathyType4 Original 1 == Packed red blood cell concentrates (pRBCs)
2 == Fresh whole blood
3 == Fresh frozen plasma (FFP)
4 == Freeze dried plasma / lypholized plasma
5 == Platelet concentrates
6 == PCC (prothrombin complex concentrates)
7 == Fibrinogen concentrate
8 == Albumin
9 == Recombinant factor FVIIa
10 == Tranexamic acid (TXA)
11 == Cryoprecipitate
12 == Desmopression (DDAVP)
13 == Factor XIII
14 == Calcium
15 == Vitamin K (Konakion)
Reflects the type of transfusion or coagulopathy treatment given in the ER of the study hospital (if applicable)
InjuryHx.EDCoagulopathyVolume1 Original Reflects the volume of transfusion or coagulopathy treatment given in the ER of the study hospital (if applicable)
InjuryHx.EDCoagulopathyVolume2 Original Reflects the volume of transfusion or coagulopathy treatment given in the ER of the study hospital (if applicable)
InjuryHx.EDCoagulopathyVolume3 Original Reflects the volume of transfusion or coagulopathy treatment given in the ER of the study hospital (if applicable)
InjuryHx.EDCoagulopathyVolume4 Original Reflects the volume of transfusion or coagulopathy treatment given in the ER of the study hospital (if applicable)
InjuryHx.EDCompEventHypothermia Original 0 == No
1 == Definite
2 == Suspect
88 == Unknown
Second Insults reported here relate to the pre-hospital and ER phase. Hypothermia is defined as a documented core temperature of < 35 C.
InjuryHx.EDComplEventCardArr Original 0 == No
1 == Yes
Second Insults reported here relate to the pre-hospital and ER phase: Cardiac Arrest
InjuryHx.EDComplEventHypotension Original 0 == No
1 == Definite
2 == Suspect
88 == Unknown
Second Insults reported here relate to the pre-hospital and ER phase. Definite hypotension is defined as a documented systolic BP < 90 mm Hg (adults); "Suspected" was scored if the patient did not have a documented blood pressure, but was reported to be in shock or have an absent brachial pulse (not related to injury of the extremity)
InjuryHx.EDComplEventHypoxia Original 0 == No
1 == Definite
2 == Suspect
88 == Unknown
Second Insults reported here relate to the pre-hospital and ER phase. Definite hypoxia is defined as a documented PaO2 <8 kPa (60 mm Hg) and/or SaO2<90%; "Suspected" was scored if the patient did not have documented hypoxia by PaO2 or SaO2, but there was a clinical suspicion , as evidenced by for example cyanosis, apnoea or respiratory distress
InjuryHx.EDComplEventSeizures Original 0 == No
1 == Partial/Focal
2 == Generalized
3 == Status epilepticus
88 == Unknown
Second Insults reported here relate to the pre-hospital and ER phase: seizures
InjuryHx.EDCorrCoagulopathy Original 0 == No
1 == Yes
88 == Unknown
Documents blood transfusions and treatment of coagulopathy in the acute phase at presentation.
InjuryHx.EDDischDate Original Documents the date of discharge from the ER/admission to Ward/ICU
InjuryHx.EDDischPupilLftEyeMeasr Original 1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
7 == 7
8 == 8
9 == 9
10 == 10
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This reflects the size of the left eye pupil for the assessment POST­-STABILIZATION.
InjuryHx.EDDischPupilLftEyeMeasrUnkUnt Original 66 == Untestable
88 == Unknown
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This reflects is left eye pupil was Untestable/Unknown for the assessment POST­-STABILIZATION.
InjuryHx.EDDischPupilReactivityLghtLftEyeReslt Original 1 == + (Brisk)
2 == + (Sluggish)
3 == - (Negative)
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This reflects the reactivity of the left eye pupil for the assessment POST­-STABILIZATION.
InjuryHx.EDDischPupilReactivityLghtRtEyeReslt Original 1 == + (Brisk)
2 == + (Sluggish)
3 == - (Negative)
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This reflects the reactivity of the right eye pupil for the assessment POST­-STABILIZATION.
InjuryHx.EDDischPupilRtEyeMeasr Original 1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
7 == 7
8 == 8
9 == 9
10 == 10
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This reflects the size of the right eye pupil for the assessment POST­-STABILIZATION.
InjuryHx.EDDischPupilRtEyeMeasrUnkUnt Original 66 == Untestable
88 == Unknown
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This reflects if right eye pupil was Untestable/Unknown for the assessment POST­-STABILIZATION.
InjuryHx.EDDischPupilSymmetry Original 1 == Equal
2 == Unequal R>L
3 == Unequal L>R
66 == Untestable
88 == Unknown
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This reflects pupil symmetry for the assessment POST­-STABILIZATION.
InjuryHx.EDDischTime Original Documents the time of discharge from the ER/admission to Ward/ICU
InjuryHx.EDICPMonitoring Original 0 == No
1 == Yes
88 == Unknown
Scheduled for ICP monitoring; e.g. may not accurately reflect if ICP monitoring was indeed performed
InjuryHx.EDIVAlbumin Original Records treatment performed in the ER/on admission with regard to Circulation: IV fluids --> Albumin
InjuryHx.EDIVBlood Original Records treatment performed in the ER/on admission with regard to Circulation: IV fluids --> Blood
InjuryHx.EDIVColloids Original Records treatment performed in the ER/on admission with regard to Circulation: IV fluids --> Colloids
InjuryHx.EDIVCrystalloids Original Records treatment performed in the ER/on admission with regard to Circulation: IV fluids --> Crystalloids
InjuryHx.EDIVMannitol Original Records treatment performed in the ER/on admission with regard to Circulation: IV fluids --> Mannitol
InjuryHx.EDIVSaline Original Records treatment performed in the ER/on admission with regard to Circulation: IV fluids --> Hypertonic saline
InjuryHx.EDSecondInsultsNeuroWorse Original 0 == No
1 == Yes
88 == Unknown
The importance of Neuroworsening was first described by Morris and Marshall. The occurrence of neuroworsening is related to poorer outcome in subjects with moderate to severe TBI. Neuroworsening is defined as 1) a decrease in GCS motor score of 2 or more points; 2) a new loss of pupillary reactivity or development of pupillary assymmetry >= 2mm; 3) deterioration in neurological or CT status sufficient to warrant immediate medical or surgical intervention
InjuryHx.EDSecondInsultsNeuroWorseYes Original 1 == Decrease in motor score >= 2 points
2 == Development of pupillary abnormalities
3 == Other neurological and/or CT deterioration
This variable provides a specification of the type of neuroworsening if it occurs.
InjuryHx.EDSecondInsultsPreAdmisCourse Original 0 == Deterioration
1 == Stable
2 == Improving
88 == Unknown
The pre-admission course should only be considered an intracranial second insult in case of Deterioration. The nature of deterioration will in most cases be further detailed under the variable "Neuroworsening".
InjuryHx.EDSpinalImmob Original 0 == No
1 == Yes
88 == Unknown
Records treatment performed in the ER/on admission with regard to Spinal immobilization. Pre-hospital inteventions are documented at: InjuryHx.PresEmergencyCare
InjuryHx.EmergSurgInterventionsExtraCran Original 0 == No
1 == Yes
88 == Unknown
Documents emergency extracranial surgery performed in study hospital. Procedures performed in "first" hospital (in case of secondary referral) are documented at: InjuryHx.PresERextracranialSurg
InjuryHx.EmergSurgInterventionsExtraCranYes Original 1 == Damage control thoracotomy
2 == Damage control laparotomy
3 == Extraperitoneal pelvic packing
4 == External fixation limb
5 == Cranio-maxillo-facial reconstruction
99 == Other
Documents emergency extracranial surgery performed in study hospital. Procedures performed in "first" hospital (in case of secondary referral) are documented at: InjuryHx.PresERextracranialSurg
InjuryHx.EmergSurgInterventionsExtraCranYesOther Original Documents emergency extracranial surgery performed in study hospital. Procedures performed in "first" hospital (in case of secondary referral) are documented at: InjuryHx.PresERextracranialSurg
InjuryHx.EmergSurgInterventionsIntraCran Original 0 == No
1 == Yes
88 == Unknown
Documents emergency intracranial surgery performed in study hospital. Procedures performed in "first" hospital (in case of secondary referral) are documented at: InjuryHx.PresERIntracranialSurg
InjuryHx.EmergSurgInterventionsIntraCranYes Original 1 == Craniotomy for haematoma/contusion
2 == Decompressive Craniectomy
3 == Depressed skull fracture
99 == Other intracranial procedure
Documents emergency intracranial surgery performed in study hospital. Procedures performed in "first" hospital (in case of secondary referral) are documented at: InjuryHx.PresERIntracranialSurg
InjuryHx.EmerSurgIntraCranSurviveNoSurg Original "InjuryHx.EmerSurgIntraCranSurviveNoSurg" and "InjuryHx.EmerSurgIntraCranSurviveYesSurg" These 2 variables aim to capture information on the surgeon's expectations, eg if the surgeon considers a realistic expectation of benefit, or performs the surgery as a "last resort" in a likely hopeless case. 'The short term survival chances of the patients if I DO NOT operate will be (in %)'
InjuryHx.EmerSurgIntraCranSurviveYesSurg Original "InjuryHx.EmerSurgIntraCranSurviveNoSurg" and "InjuryHx.EmerSurgIntraCranSurviveYesSurg" These 2 variables aim to capture information on the surgeon's expectations, eg if the surgeon considers a realistic expectation of benefit, or performs the surgery as a "last resort" in a likely hopeless case. 'The short term survival chances of the patients if I DO operate will be (in %)'
InjuryHx.ERDestICDCodes1 Original Up to 16 fields available to enter diagnosis as recorded by hospital administration according to ICD codes; applicable to patients discharged directly from the ER. For patients admitted to hospital or ICU, ICD codes are documented in: Hospital.ICDCode1 and Hospital.ICUDischargeICDCode1
InjuryHx.ERDestICDCodes10 Original Up to 16 fields available to enter diagnosis as recorded by hospital administration according to ICD codes; applicable to patients discharged directly from the ER. For patients admitted to hospital or ICU, ICD codes are documented in: Hospital.ICDCode1 and Hospital.ICUDischargeICDCode1
InjuryHx.ERDestICDCodes11 Original Up to 16 fields available to enter diagnosis as recorded by hospital administration according to ICD codes; applicable to patients discharged directly from the ER. For patients admitted to hospital or ICU, ICD codes are documented in: Hospital.ICDCode1 and Hospital.ICUDischargeICDCode1
InjuryHx.ERDestICDCodes12 Original Up to 16 fields available to enter diagnosis as recorded by hospital administration according to ICD codes; applicable to patients discharged directly from the ER. For patients admitted to hospital or ICU, ICD codes are documented in: Hospital.ICDCode1 and Hospital.ICUDischargeICDCode1
InjuryHx.ERDestICDCodes13 Original Up to 16 fields available to enter diagnosis as recorded by hospital administration according to ICD codes; applicable to patients discharged directly from the ER. For patients admitted to hospital or ICU, ICD codes are documented in: Hospital.ICDCode1 and Hospital.ICUDischargeICDCode1
InjuryHx.ERDestICDCodes14 Original Up to 16 fields available to enter diagnosis as recorded by hospital administration according to ICD codes; applicable to patients discharged directly from the ER. For patients admitted to hospital or ICU, ICD codes are documented in: Hospital.ICDCode1 and Hospital.ICUDischargeICDCode1
InjuryHx.ERDestICDCodes15 Original Up to 16 fields available to enter diagnosis as recorded by hospital administration according to ICD codes; applicable to patients discharged directly from the ER. For patients admitted to hospital or ICU, ICD codes are documented in: Hospital.ICDCode1 and Hospital.ICUDischargeICDCode1
InjuryHx.ERDestICDCodes16 Original Up to 16 fields available to enter diagnosis as recorded by hospital administration according to ICD codes; applicable to patients discharged directly from the ER. For patients admitted to hospital or ICU, ICD codes are documented in: Hospital.ICDCode1 and Hospital.ICUDischargeICDCode1
InjuryHx.ERDestICDCodes2 Original Up to 16 fields available to enter diagnosis as recorded by hospital administration according to ICD codes; applicable to patients discharged directly from the ER. For patients admitted to hospital or ICU, ICD codes are documented in: Hospital.ICDCode1 and Hospital.ICUDischargeICDCode1
InjuryHx.ERDestICDCodes3 Original Up to 16 fields available to enter diagnosis as recorded by hospital administration according to ICD codes; applicable to patients discharged directly from the ER. For patients admitted to hospital or ICU, ICD codes are documented in: Hospital.ICDCode1 and Hospital.ICUDischargeICDCode1
InjuryHx.ERDestICDCodes4 Original Up to 16 fields available to enter diagnosis as recorded by hospital administration according to ICD codes; applicable to patients discharged directly from the ER. For patients admitted to hospital or ICU, ICD codes are documented in: Hospital.ICDCode1 and Hospital.ICUDischargeICDCode1
InjuryHx.ERDestICDCodes5 Original Up to 16 fields available to enter diagnosis as recorded by hospital administration according to ICD codes; applicable to patients discharged directly from the ER. For patients admitted to hospital or ICU, ICD codes are documented in: Hospital.ICDCode1 and Hospital.ICUDischargeICDCode1
InjuryHx.ERDestICDCodes6 Original Up to 16 fields available to enter diagnosis as recorded by hospital administration according to ICD codes; applicable to patients discharged directly from the ER. For patients admitted to hospital or ICU, ICD codes are documented in: Hospital.ICDCode1 and Hospital.ICUDischargeICDCode1
InjuryHx.ERDestICDCodes7 Original Up to 16 fields available to enter diagnosis as recorded by hospital administration according to ICD codes; applicable to patients discharged directly from the ER. For patients admitted to hospital or ICU, ICD codes are documented in: Hospital.ICDCode1 and Hospital.ICUDischargeICDCode1
InjuryHx.ERDestICDCodes8 Original Up to 16 fields available to enter diagnosis as recorded by hospital administration according to ICD codes; applicable to patients discharged directly from the ER. For patients admitted to hospital or ICU, ICD codes are documented in: Hospital.ICDCode1 and Hospital.ICUDischargeICDCode1
InjuryHx.ERDestICDCodes9 Original Up to 16 fields available to enter diagnosis as recorded by hospital administration according to ICD codes; applicable to patients discharged directly from the ER. For patients admitted to hospital or ICU, ICD codes are documented in: Hospital.ICDCode1 and Hospital.ICUDischargeICDCode1
InjuryHx.ERDestICDCodesVersion Original 9 == ICD-9
10 == ICD-10
Reflects the version used: ICD-9 or ICD-10. Up to 16 fields available to enter diagnosis as recorded by hospital administration according to ICD codes; applicable to patients discharged directly from the ER. For patients admitted to hospital or ICU, ICD codes are documented in: Hospital.ICDCode1 and Hospital.ICUDischargeICDCode1
InjuryHx.ERDischHomeSchedApptOutpatient Original 0 == No
1 == Yes
88 == Unknown
Reflects the scheduled appointments for patients discharged from ER to home or to another facility. The scheduled appointments gives details on Out­patient visit, Referred to general practitioner, study protocol follow up and MR study planned.
InjuryHx.ERDischHomeSchedApptOutpatientDate Original Reflects the scheduled appointments for patients discharged from ER to home or to another facility. The scheduled appointments gives details on Out­patient visit, Referred to general practitioner, study protocol follow up and MR study planned.
InjuryHx.ERDischHomeSchedApptReferToGP Original 0 == No
1 == Yes
88 == Unknown
Reflects the scheduled appointments for patients discharged from ER to home or to another facility. The scheduled appointments gives details on Out­patient visit, Referred to general practitioner, study protocol follow up and MR study planned.
InjuryHx.ERDischHomeSchedApptStudyProtoFU Original 0 == No
1 == Yes
88 == Unknown
Reflects the scheduled appointments for patients discharged from ER to home or to another facility. The scheduled appointments gives details on Out­patient visit, Referred to general practitioner, study protocol follow up and MR study planned.
InjuryHx.ERDischHomeTypeOfCarePlanned Original 0 == None
1 == Symptomatic treatment or/and advice for the next 24/48h
2 == Systematic follow-up visit by GP
3 == Systematic follow-up visit by specialist practitioner
4 == Oral information on TBI, its possible late consequences, and where to consult in case of difficulties
5 == Written information on TBI, its possible late consequences, and where to consult in case of difficulties
Reflects the type of care planned for patients discharged from ER to home or to another facility.
InjuryHx.ERDischMotivForDestChoice Original 1 == Normal CT
2 == Medical necessity
3 == Social circumstances
4 == No (ICU-) beds available
5 == Requiring specialized facilities
88 == Unknown
99 == Other
WHY Question: documents main reason for choice of destination at ER discharge.
InjuryHx.ERDischMotivForDestChoiceOther Original WHY Question: documents main reason for choice of destination after ER discharge --> Other
InjuryHx.ExternaAIS Original 0 == 0 No Injury
1 == 1 Minor
2 == 2 Moderate
3 == 3 Serious
4 == 4 Severe
5 == 5 Critical
6 == 6 Unsurvivable
AIS score for the Externa (skin) region. In the original AIS classification of injury severity, the grading is from 1 (minor) to 6 (unsurvivable). We added a score of 0 to designate absence of injuries.
InjuryHx.ExternaDesc Original 1 == No values yet Injury description related to the AIS/ISS score for the Externa (skin) region.
InjuryHx.FaceAIS Original 0 == 0 No Injury
1 == 1 Minor
2 == 2 Moderate
3 == 3 Serious
4 == 4 Severe
5 == 5 Critical
6 == 6 Unsurvivable
AIS score for the Face (incl.maxillofacial) region In the original AIS classification of injury severity, the grading is from 1 (minor) to 6 (unsurvivable). We added a score of 0 to designate absence of injuries.
InjuryHx.FaceDesc Original 1 == Maxillo-facial fracture le Fort I
2 == Maxillo-facial fracture le Fort II
3 == Maxillo-facial fracture le Fort III
4 == Orbital fracture
5 == Zygomatic arch fracture
99 == Other
Injury description related to the AIS/ISS score for the Face (incl.maxillofacial) region
InjuryHx.FirstHospAssmtCondition Original 0 == No sedation or paralysis
1 == Sedated
2 == Paralyzed
3 == Temporary stop of sedation/paralysis
4 == Reversal of sedation/paralysis
5 == Active reversal (pharmacologic) of sedation/paralysis
99 == Other
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This Describes the condition under which the GCS was assessed at First Hospital.
InjuryHx.GcsEDArrAssmtCond Original 0 == No sedation or paralysis
1 == Sedated
2 == Paralyzed
3 == Temporary stop of sedation/paralysis
4 == Reversal of sedation/paralysis
5 == Active reversal (pharmacologic) of sedation/paralysis
99 == Other
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This describes the condition under which the GCS was assessed at Arrival to ER of the study hospital.
InjuryHx.GCSEDArrEyes Original O == Untestable (other)
UN == Unknown
S == Untestable (swollen)
1 == 1-None
2 == 2-To pain
3 == 3-To speech
4 == 4-Spontaneously
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This reflects the GCS Eye opening at Arrival to ER of study hospital.
InjuryHx.GCSEDArrMotor Original UN == Unknown
O == Untestable (Other)
P == Untestable (Deep sedation/paralyzed)
1 == 1-None
2 == 2-Abnormal extension
3 == 3-Abnormal flexion
4 == 4-Normal flexion/withdrawal
5 == 5-Localizes to pain
6 == 6-Obeys command
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This reflects the GCS Motor score at Arrival to ER of study hospital.
InjuryHx.GcsEDArrNotDone Original 77 == Not done / Results not available Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This indicates that GCS at Arrival to Study hospital was not done.
InjuryHx.GCSEDArrScore Calculated Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This is a Calculated score for Arrival at ER of study hospital: GCSEDArrEyes + GCSEDArrMotor + GCSEDArrVerbal. If one or more of these is Untestable or unknown then = "No Sum"
InjuryHx.GcsEDArrScoreDate Original Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This reflects the date of assessment at Arrival to ER of the study hospital.
InjuryHx.GcsEDArrScoreTime Original Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This reflects the time of assessment at Arrival to ER of the study hospital.
InjuryHx.GCSEDArrVerbal Original UN == Unknown
O == Untestable (Other)
T == Untestable (Tracheotomy/endotracheal tube)
1 == 1-None
2 == 2-Incomprehensible sound
3 == 3-Inappropriate words
4 == 4-Confused
5 == 5-Oriented
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This reflects GCS Verbal score at Arrival to ER of study hospital
InjuryHx.GcsEDDischAssmtCond Original 0 == No Sedation or Paralysis
1 == Sedated
2 == Paralyzed
3 == Temporary stop of sedation/paralysis
4 == Reversal of sedation/paralysis
5 == Active reversal (pharmacologic) of sedation/paralysis
99 == Other
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This describes the condition under which the GCS was assessed POST-STABILIZATION.
InjuryHx.GCSEDDischEyes Original S == Untestable (swollen)
UN == Unknown
O == Untestable (other)
1 == 1-None
2 == 2-To pain
3 == 3-To speech
4 == 4-Spontaneously
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This reflects GCS eye opening for the assessment POST­-STABILIZATION.
InjuryHx.GCSEDDischMotor Original O == Untestable (Other)
UN == Unknown
P == Untestable (Deep sedation/paralyzed)
1 == 1-None
2 == 2-Abnormal extension
3 == 3-Abnormal flexion
4 == 4-Normal flexion/withdrawal
5 == 5-Localizes to pain
6 == 6-Obeys command
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This reflects GCS Motor score for the assessment POST­-STABILIZATION.
InjuryHx.GcsEDDischNotDone Original 77 == Not done / Results not available Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This indicates that GCS at Post-stabilization was not done.
InjuryHx.GCSEDDischScore Calculated Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This is the Calculated score for the POST-STABILIZATION assessment: GCSEDDischEyes + GCSEDDischMotor + GCSEDDischVerbal. If one or more of these is Untestable or unknown then = "No Sum"
InjuryHx.GcsEDDischScoreDate Original Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This reflects Date for the assessment POST­-STABILIZATION.
InjuryHx.GcsEDDischScoreTime Original Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This reflects the Time for the assessment POST­-STABILIZATION.
InjuryHx.GCSEDDischVerbal Original UN == Unknown
O == Untestable (Other)
T == Untestable (Tracheotomy/endotracheal tube)
1 == 1-None
2 == 2-Incomprehensible sound
3 == 3-Inappropriate words
4 == 4-Confused
5 == 5-Oriented
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This reflects GCS Verbal score for the assessment POST­-STABILIZATION.
InjuryHx.GCSFirstHospEyes Original UN == Unknown
O == Untestable (other)
S == Untestable (swollen)
1 == 1-None
2 == 2-To pain
3 == 3-To speech
4 == 4-Spontaneously
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This reflects GCS eye opening for the assessment at First Hospital.
InjuryHx.GCSFirstHospMotor Original UN == Unknown
P == Untestable (Deep sedation/paralyzed)
O == Untestable (Other)
1 == 1-None
2 == 2-Abnormal extension
3 == 3-Abnormal flexion
4 == 4-Normal flexion/withdrawal
5 == 5-Localizes to pain
6 == 6-Obeys command
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This reflects GCS Motor score for the assessment at First Hospital.
InjuryHx.GCSFirstHospNotDone Original 77 == Not done / Results not available Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This indicates that GCS at for the assessment at First hospital was not done.
InjuryHx.GCSFirstHospPupilLftEyeMeasure Original Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This reflects Left Pupil Size for the assessment at First Hospital.
InjuryHx.GCSFirstHospPupilLftEyeMeasureUnkUnt Original 66 == Untestable
88 == Unknown
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This indicates that Left Pupil size was untestable/unknown for the assessment at First Hospital.
InjuryHx.GCSFirstHospPupilReactivityLightLftEyeReslt Original 1 == + (Sluggish)
2 == + (Brisk)
3 == - (Negative)
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This reflects the reactivity of the Left Pupil for the assessment at First Hospital.
InjuryHx.GCSFirstHospPupilReactivityLightRghtEyeReslt Original 1 == + (Sluggish)
2 == + (Brisk)
3 == - (Negative)
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This reflects the reactivity of the Right Pupil for the assessment at First Hospital.
InjuryHx.GCSFirstHospPupilRightEyeMeasure Original Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This reflects Right Pupil Size for the assessment at First Hospital.
InjuryHx.GCSFirstHospPupilRightEyeMeasureUnkUnt Original 66 == Untestable
88 == Unknown
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This reflects that the Right Pupil size was Untestable/Unknown for the assessment at First Hospital.
InjuryHx.GCSFirstHospPupilSymmetry Original 1 == Equal
2 == Unequal R>L
3 == Unequal L>R
66 == Untestable
88 == Unknown
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This reflects the pupil symmetry for the assessment at First Hospital.
InjuryHx.GCSFirstHospReportedTotalScore Original 3 == 3
4 == 4
5 == 5
6 == 6
7 == 7
8 == 8
9 == 9
10 == 10
11 == 11
12 == 12
13 == 13
14 == 14
15 == 15
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This reflects Score by investigators in case component scores not available, but GCS sum score available for the assessment at First Hospital.
InjuryHx.GCSFirstHospScore Calculated Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This is the Calculated Score for the assessment at First Hospital: GCSFirstHospEyes + GCSFirstHospMotor + GCSFirstHospVerbal. If one or more of these is Untestable or unknown then = "No Sum" Sum Score may be recorded with no components
InjuryHx.GCSFirstHospScoreDate Original Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This reflects the Date for the assessment at First Hospital.
InjuryHx.GCSFirstHospScoreTime Original Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This reflects the Time for the assessment at First Hospital.
InjuryHx.GCSFirstHospVerbal Original UN == Unknown
O == Untestable (Other)
T == Untestable (tracheotomy/endotracheal tube)
1 == 1-None
2 == 2-Incomprehensible sound
3 == 3-Inappropriate words
4 == 4-Confused
5 == 5-Oriented
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This reflects the GCS Verbal score for the assessment at First Hospital.
InjuryHx.GCSMotorBaselineDerived Derived This is a derived variable calculated centrally. It represents the GCS motor score for baseline risk adjustment with missing values imputed using IMPACT methodology - take Poststabilisation value and if absent work back in time towards prehospital values until non-missing value found. RECOMMENDED FOR BASELINE RISK ADJUSTMENT.
InjuryHx.GCSOtherAssmtConditions Original 0 == No Sedation or Paralysis
1 == Sedated
2 == Paralyzed
3 == Temporary stop of sedation/paralysis
4 == Reversal of sedation/paralysis
5 == Active reversal (pharmacologic) of sedation/paralysis
99 == Other
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. There was also an additional option "Other" assessment. This describes the condition under which the GCS was assessed for the assessment "Other".
InjuryHx.GCSOtherDate Original Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. There was also an additional option "Other" assessment. This describes the Date for the assessment "Other".
InjuryHx.GCSOtherEyes Original S == Untestable (swollen)
UN == Unknown
O == Untestable (other)
1 == 1-None
2 == 2-To pain
3 == 3-To speech
4 == 4-Spontaneously
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. There was also an additional option "Other" assessment. This describes the GCS Eye opening for the assessment "Other".
InjuryHx.GCSOtherMotor Original UN == Unknown
O == Untestable (Other)
P == Untestable (Deep sedation/paralyzed)
1 == 1-None
2 == 2-Abnormal extension
3 == 3-Abnormal flexion
4 == 4-Normal flexion/withdrawal
5 == 5-Localizes to pain
6 == 6-Obeys command
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. There was also an additional option "Other" assessment. This describes GCS Motor score for the assessment "Other".
InjuryHx.GCSOtherNotDone Original 77 == Not done / Results not available Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. There was also an additional option "Other" assessment. This indicates that GCS was not done for the assessment "Other".
InjuryHx.GCSOtherPupilLftEyeMeasure Original Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. There was also an additional option "Other" assessment. This describes Left Pupil Size for the assessment "Other".
InjuryHx.GCSOtherPupilLftEyeMeasureUnkUnt Original 66 == Untestable
88 == Unknown
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. There was also an additional option "Other" assessment. This reflects when the Left Pupil Size was Untestable/Unknown for the assessment "Other".
InjuryHx.GCSOtherPupilReactivityLightLftEyeReslt Original 1 == + (Sluggish)
2 == + (Brisk)
3 == - (Negative)
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. There was also an additional option "Other" assessment. This describes the reactivity of the LEFT pupil for the assessment "Other".
InjuryHx.GCSOtherPupilRightEyeMeasure Original Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. There was also an additional option "Other" assessment. This describes the Right pupil size for the assessment "Other".
InjuryHx.GCSOtherPupilSymmetry Original 1 == Equal
2 == Unequal R>L
3 == Unequal L>R
66 == Untestable
88 == Unknown
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. There was also an additional option "Other" assessment. This describes the pupil symmetry for the assessment "Other".
InjuryHx.GCSOtherReactivityLightRghtEyeReslt Original 1 == + (Sluggish)
2 == + (Brisk)
3 == - (Negative)
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. There was also an additional option "Other" assessment. This describes the reactivity of the Right Pupil for the assessment "Other".
InjuryHx.GCSOtherRightEyeMeasureUnkUnt Original 66 == Untestable
88 == Unknown
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. There was also an additional option "Other" assessment. This reflects if the Right pupil was Untestable/Unknown for the assessment "Other".
InjuryHx.GCSOtherScore Calculated Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. There was also an additional option "Other" assessment. This is the Calculated Score for the assessment "Other": GCSOtherEyes + GCSOtherMotor + GCSOtherVerbal. If one or more of these is Untestable or unknown then = "No Sum" Sum score may be reported when components not available
InjuryHx.GCSOtherTime Original Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. There was also an additional option "Other" assessment. This reflects the Time for the assessment "Other".
InjuryHx.GCSOtherVerbal Original UN == Unknown
O == Untestable (Other)
T == Untestable (tracheotomy/endotracheal tube)
1 == 1-None
2 == 2-Incomprehensible sound
3 == 3-Inappropriate words
4 == 4-Confused
5 == 5-Oriented
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. There was also an additional option "Other" assessment. This describes the GCS Verbal score for the assessment "Other".
InjuryHx.GcsPreHospBestDate Original Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This describes the Date for the assessment at Scene Of Accident.
InjuryHx.GCSPreHospBestEyes Original UN == Unknown
O == Untestable (Other)
S == Untestable (swollen)
1 == 1-None
2 == 2-To pain
3 == 3-To speech
4 == 4-Spontaneously
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This describes the GCS Eye opening for the assessment at Scene Of Accident.
InjuryHx.GCSPreHospBestMotor Original UN == Unknown
O == Untestable (Other)
P == Untestable (Deep sedation/paralyzed)
1 == 1-None
2 == 2-Abnormal extension
3 == 3-Abnormal flexion
4 == 4-Normal flexion/withdrawal
5 == 5-Localizes to pain
6 == 6-Obeys command
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This describes the GCS Motor score for the assessment at Scene Of Accident.
InjuryHx.GCSPreHospBestReportedTotalScore Calculated 3 == 3
4 == 4
5 == 5
6 == 6
7 == 7
8 == 8
9 == 9
10 == 10
11 == 11
12 == 12
13 == 13
14 == 14
15 == 15
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. Score by investigators in case the component scores are not available, but GCS sum score available for the assessment at Scene Of Accident.
InjuryHx.GCSPreHospBestScore Calculated Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This is the Calculated Score for the assessment at Scene Of Accident: GCSPreHospBestEyes + GCSPreHospBestMotor + GCSPreHospBestVerbal. If one or more of these is Untestable or unknown then = "No Sum" GCS sum score may be recorded when components not available - check "InjuryHx.GCSPreHospBestReportedTotalScore"
InjuryHx.GcsPreHospBestTime Original Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This describes the Time for the assessment at Scene Of Accident.
InjuryHx.GCSPreHospBestVerbal Original O == Untestable (Other)
UN == Unknown
T == Untestable (Tracheotomy/endotracheal tube)
1 == 1-None
2 == 2-Incomprehensible sound
3 == 3-Inappropriate words
4 == 4-Confused
5 == 5-Oriented
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This describes the GCS Verbal score for the assessment at Scene Of Accident.
InjuryHx.GcsPreHospLftEyeMeasr Original 1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
7 == 7
8 == 8
9 == 9
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This describes the Left Pupil Size for the assessment at Scene Of Accident.
InjuryHx.GcsPreHospNotDone Original 77 == Not Done / Results not available Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. Indication that GCS for the assessment at Scene of accident was not done.
InjuryHx.GCSPreHospPupilLftEyeMeasureUnkUnt Original 66 == Untestable
88 == Unknown
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This describes if the Left Pupil was Untestable/Unknown for the assessment at Scene Of Accident.
InjuryHx.GCSPreHospPupilReactivityLghtLftEyeResult Original 1 == + (Sluggish)
2 == + (Brisk)
3 == - (Negative)
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This describes the reactivity of the Left pupil for the assessment at Scene Of Accident.
InjuryHx.GCSPreHospPupilReactivityLghtRghtEyeResult Original 1 == + (Sluggish)
2 == + (Brisk)
3 == - (Negative)
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This describes the reactivity of the Right pupil for the assessment at Scene Of Accident.
InjuryHx.GCSPreHospPupilRightEyeMeasureUnkUnt Original 66 == Untestable
88 == Unknown
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This reflects if the Right Pupil was Untestable/Unknown for the assessment at Scene Of Accident.
InjuryHx.GCSPreHospPupilSymmetry Original 1 == Equal
2 == Unequal R>L
3 == Unequal L>R
66 == Untestable
88 == Unknown
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This describes the Pupil symmetry for the assessment at Scene Of Accident.
InjuryHx.GcsPreHospRghtEyeMeasr Original 1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
7 == 7
8 == 8
9 == 9
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This describes the Right Pupil Size for the assessment at Scene Of Accident.
InjuryHx.GCSScoreBaselineDerived Derived This is a derived variable calculated centrally. It represents the total GCS (single timepoint) for baseline risk adjustment with missing values imputed using IMPACT methodology - take Poststabilisation value and if absent work back in time towards prehospital values until non-missing value found. Intubated / untestable V score treated as unknown. RECOMMENDED FOR BASELINE RISK ADJUSTMENT.
InjuryHx.HeadNeckAIS Original 0 == 0 No Injury
1 == 1 Minor
2 == 2 Moderate
3 == 3 Serious
4 == 4 Severe
5 == 5 Critical
6 == 6 Unsurvivable
AIS score for the Head and Neck region. In the original AIS classification of injury severity, the grading is from 1 (minor) to 6 (unsurvivable). We added a score of 0 to designate absence of injuries.
InjuryHx.HeadNeckDesc Original Injury description for the Head and Neck AIS.
InjuryHx.HighestGCSMotorDerived Derived This is a derived variable calculated centrally. It represents the GCS motor score for baseline risk adjustment with missing values imputed using ‘highest’ value (best neurology) methodology- take best neurology of any of prehospital to Poststabilisation time points. DEPRECATED: we recommend using GCSMotorBaselineDerived for baseline risk adjustment instead (higher pseudo-R-squared in proportional odds model).
InjuryHx.HighestGCSTotalDerived Derived This is a derived variable calculated centrally. Total GCS (single timepoint) for baseline risk adjustment with missing values imputed using ‘highest’ value (best neurology) methodology - take best neurology of any of prehospital to Poststabilisation time points. Intubated / untestable V score treated as unknown. DEPRECATED: we recommend using GCSScoreBaselineDerived for baseline risk adjustment instead (higher pseudo-R-squared in proportional odds model).
InjuryHx.HighestPupilsDerived Derived 0 - Both reacting
1 - One reacting (other pupil is either unreactive, missing or untestable)
This is a derived variable calculated centrally. Number of unreactive pupils for baseline risk adjustment with missing values imputed using ‘highest’ value (best neurology) methodology- take best neurology of any of prehospital to Poststabilisation time points. Untestable pupil ignored: I.e. 1 reactive + 1 untestable = 1 reactive (this assumption applies only to a small proportion of the data). DEPRECATED: we recommend using PupilsBaselineDerived for baseline risk adjustment instead (higher pseudo-R-squared in proportional odds model).
InjuryHx.InjArea Original 1 == Urban (city)
2 == Rural
88 == Unknown
Reflects the area where the injury took place (urban or rural).
InjuryHx.InjCause Original 1 == Road traffic incident
2 == Incidental fall
3 == Other non-intentional injury
4 == Violence/assault
5 == Act of mass violence
6 == Suicide attempt
88 == Unknown
99 == Other
Reflects the cause of injury.
InjuryHx.InjCauseOther Original Reflects if the cause of injury was "other" than the pre-listed causes. See also InjuryHx.InjCause
InjuryHx.InjIndContactSportType Original 1 == Boxing
2 == Martial Arts
99 == Other
Reflects the kind of contact sport involved as cause of injury - Only applicable for sports/recreational injuries
InjuryHx.InjIndSportTypeOther Original Reflects if the kind of contact sport involved as cause of injury was "other" than the pre-defined list - Only applicable for sports/recreational injuries. See also InjuryHx.InjIndContactSportType
InjuryHx.InjIntention Original 1 == Intentional
2 == Unintentional
3 == Undetermined
Reflects if the cause on injury was intentional or unintentional.
InjuryHx.InjMech Original 1 == High velocity trauma (acceleration/deceleration)
2 == Direct impact: blow to head
3 == Direct impact: head against object
6 == Ground level fall
7 == Fall from height > 1 meter/5 stairs
99 == Other closed head injury
Reflects the mechanism of injury - only applicable for Closed TBI
InjuryHx.InjMechOther Original Reflects if the mechanism of injury was "other" than the pre-defined list - only applicable for Closed TBI. See also InjuryHx.InjMech
InjuryHx.InjOtherPartyInvolved Original 77 == N/A Reflects that "another party involved in the cause of injury = N/A".
InjuryHx.InjOtherPartySleepingPills Original 0 == No
1 == Suspect
2 == Definite
88 == Unknown
Reflects if sedatives or sleeping pills were involved in the cause of injury.
InjuryHx.InjPenetratingType Original 1 == Gunshot wound
2 == Fragment (incl. shell/shrapnel)
99 == Other penetrating brain injury
Reflects the mechanism of injury - only applicable if Penetrating brain injury
InjuryHx.InjPenetratingTypeOther Original Reflects if the mechanism of injury was other than the pre-defined list - only applicable if Penetrating brain injury. See also InjuryHx.InjPenetratingType
InjuryHx.InjPlace Original 1 == Street/highway
2 == Home/domestic
3 == Work/school
4 == Sport/Recreational
5 == Military deployment
6 == Public location (eg. bar, station, nightclub)
88 == Unknown
99 == Other
Reflects the place where the TBI injury occurred.
InjuryHx.InjPlaceOther Original Reflects if the place where the TBI injury occurred was "other" than the pre-defined list. See also InjuryHx.InjPlace
InjuryHx.InjRecSportType Original 1 == Rollerblading/Skateboarding/Scootering
2 == Skiing
3 == Snowboarding
4 == Hiking/Climbing
5 == Horseriding
6 == Golf
7 == Cycling
8 == Off-road vehicular sports
9 == Water sports
10 == Playground activity
88 == Unknown
99 == Other
Reflects of the cause of injury was "Other Sport & Recreational Activities" - Only applicable for sports/recreational injuries
InjuryHx.InjRecSportTypeOther Original Describes which was the cause of injury if "Other Sport & Recreational Activities" - Only applicable for sports/recreational injuries
InjuryHx.InjRoadAccEjectedFromVehicle Original 0 == No
1 == Yes
88 == Unknown
Reflects if the subject was ejected from the vehicle - Only applicable if subject was motor vehicle occupant
InjuryHx.InjRoadAccOtherParty Original 1 == Motor vehicle
2 == Pedestrian
3 == Cyclist
4 == Moped/Scooter
5 == Tram/Bus
6 == Train/Metro
7 == Obstacle
10 == Motor Bike
11 == Lorry (camion)
88 == Unknown
99 == Other
Reflects if another party was involved in the Cause of Injury in case of a Road Traffic accident
InjuryHx.InjRoadAccOtherPartyInvolved Original 0 == No
1 == Yes
88 == Unknown
Describes if another party than the pre-defined list was involved in the Cause of Injury in case of a Road Traffic accident
InjuryHx.InjRoadAccOtherPartyOther Original Describes which other party than the pre-defined list was involved in the Cause of Injury in case of a Road Traffic accident
InjuryHx.InjRoadAccVictim Original 1 == Motor vehicle occupant
2 == Pedestrian
3 == Cyclist
4 == Moped/Scooter
5 == Motor Bike
99 == Other
Describes the type of victim in case of a Road traffic accident.
InjuryHx.InjRoadAccVictimOther Original Reflects if the type of victim was "other" than the predefined list in case of a Road traffic accident.
InjuryHx.InjRoadAccVictimVehiclePlace Original 1 == Driver
2 == Front seat passenger
3 == Back seat passenger
Reflects the occupant placement of the victim in the vehicle in case of a Road Traffic Accident
InjuryHx.InjSafetyAirbag Original 0 == No
1 == Yes
77 == Not Applicable
88 == Unknown
Perfects if the airbag was deployed - Only applicable if subject was motor vehicle occupant
InjuryHx.InjSafetyHelmet Original 0 == No
1 == Yes
77 == Not Applicable
88 == Unknown
Reflects if the victim was wearing a safety helmet. Only applicable in case of cyclist, scooter, motorbike incident. However, may also have been scored for various sports injuries.
InjuryHx.InjSafetySeatbelt Original 0 == No
1 == Yes
77 == Not Applicable
88 == Unknown
Reflects if the victim was wearing a seat-belt. Only applicable if subject was motor vehicle occupant
InjuryHx.InjTeamSportType Original 1 == Football (soccer)
2 == Rugby
3 == Field Hockey
4 == Ice Hockey
5 == Lacrosse
99 == Other
Reflects the type of team sport that was the cause of the injury - Only applicable for sports/recreational injuries
InjuryHx.InjTeamSportTypeOther Original Reflects if the type of team sport that was the cause of the injury was "other" than the predefined list- Only applicable for sports/recreational injuries
InjuryHx.InjType Original 1 == Closed
2 == Blast
3 == Crush
5 == Penetrating
6 == Penetrating-perforating
7 == Penetrating-tangential
8 == Closed with open depressed skull fracture
88 == Unknown
Details of Injury are captured in 4 different variables: Type of Injury, Place of Injury, Cause of Injury and Mechanism of injury. This reflects the type of injury.
InjuryHx.InjVictimAlcoholTestType Original Breath == Breath Test
Blood == Blood Test
Reflects type of alcohol test used (breath test or blood test) for the victim
InjuryHx.InjVictimBloodAlcoholmgdL Original Reflects the level of mg/dL alcohol recorded in the victim during the alcohol test in case alcohol was related to the cause of injury.
InjuryHx.InjVictimBloodAlcoholpermil Original Reflects the level of alcohol per mil (0/00) recorded in the victim during the alcohol test in case alcohol was related to the cause of injury.
InjuryHx.InjVictimBloodAlcoholUnit Original 1 == mg/dL
2 == per mil (0/00)
Reflects the value used for alcohol level recorded during the alcohol test of the victim in case alcohol was related to the cause of injury.
InjuryHx.InjVictimDrugsTypeOther Original Describes which other drugs where involved for the victim in the cause of injury.
InjuryHx.InjVictimSleepingPills Original 0 == No
1 == Suspect
2 == Definite
88 == Unknown
Reflects if for the victim use of sedatives of sleeping pills were involved in the cause of injury.
InjuryHx.InjVictimTypeDrugs Original 1 == Cannabis
2 == Cocaine
3 == Methamphetamine's
4 == Opioids
5 == XTC
88 == Unknown
99 == Other
Rf elects which kind of drugs were involved in the cause of injury at the victims site.
InjuryHx.InjViolence Original 1 == Robbery
2 == Interpersonal violence (fight)
3 == Domestic assault
4 == Child abuse
5 == Gang violence
6 == Military deployment
88 == Unknown
99 == Other
Reflects the type of violence used as cause of injury - Only applicable if violence was the cause of injury
InjuryHx.InjViolenceOther Original Reflects the "other" type of violence than the predefined list used as cause of injury - Only applicable if violence was the cause of injury
InjuryHx.InjViolenceOtherPartyAlcohol Original 0 == No
1 == Definite
2 == Suspect
88 == Unknown
Information on drug and alcohol abuse of possible influence on the incident is different for victim versus "other party" (if involved) This reflects if alcohol was involved in the cause of injury for the other party involved
InjuryHx.InjViolenceOtherPartyDrugs Original 0 == No
1 == Definite
2 == Suspect
88 == Unknown
Information on drug and alcohol abuse of possible influence on the incident is different for victim versus "other party" (if involved). This reflects if drugs was involved as cause of injury for the other party involved
InjuryHx.InjViolenceVictimAlcohol Original 0 == No
1 == Definite
2 == Suspect
88 == Unknown
Information on drug and alcohol abuse of possible influence on the incident is different for victim versus "other party" (if involved) This reflects alcohol involvement for the victim.
InjuryHx.InjViolenceVictimDrugs Original 0 == No
1 == Definite
2 == Suspect
88 == Unknown
Information on drug and alcohol abuse of possible influence on the incident is different for victim versus "other party" (if involved) This reflects drugs involvement for the victim.
InjuryHx.InterventRadiology Original 0 == No
1 == Yes
88 == Unknown
Reflects if at time of discharge from the ER some Interventional Radiology was scheduled
InjuryHx.LOCAOC Original 0 == No
1 == Yes, immediate
2 == Not tested due to LOC
3 == Suspected
4 == Yes, delayed onset
88 == Unknown
TBI may be present in the absence of LOC or PTA. Alteration of Consciousness (AOC) is then the main presenting symptom and considered diagnostic of TBI. Details of symptoms are captured in the Rivermead Questionnaire.
InjuryHx.LOCAOCDelayedHrs Original TBI may be present in the absence of LOC or PTA. Alteration of Consciousness (AOC) is then the main presenting symptom and considered diagnostic of TBI. This reflects the Number of hours after injury that alteration of consciousness occurred - Only in case of delayed onset. Details of symptoms are captured in the Rivermead Questionnaire.
InjuryHx.LOCAOCDelayedHrsUnk Original TBI may be present in the absence of LOC or PTA. Alteration of Consciousness (AOC) is then the main presenting symptom and considered diagnostic of TBI. This reflects if the Number of hours after injury that alteration of consciousness occurred = Unknown. Details of symptoms are captured in the Rivermead Questionnaire.
InjuryHx.LOCAOCDuration Original 0 == None
2 == <1 minute
3 == 1-29 minutes
4 == 30-59 minutes
5 == 1-24 hours
6 == 1-7 days
7 == >7 days
88 == Unknown
TBI may be present in the absence of LOC or PTA. Alteration of Consciousness (AOC) is then the main presenting symptom and considered diagnostic of TBI. This reflects the Duration of alteration of consciousness. Details of symptoms are captured in the Rivermead Questionnaire.
InjuryHx.LOCAOCReportedBy Original 1 == Patient
2 == Witness
3 == Clinical interview
4 == Medical chart
5 == Not available
TBI may be present in the absence of LOC or PTA. Alteration of Consciousness (AOC) is then the main presenting symptom and considered diagnostic of TBI. This reflects by whom the alteration of consciousness was reported. Details of symptoms are captured in the Rivermead Questionnaire.
InjuryHx.LOCDuration Original 0 == No return of consciousness
2 == <1 minute
3 == 1-29 minutes
4 == 30-59 minutes
5 == 1-24 hours
6 == 1-7 days
7 == >7 days
88 == Unknown
LOC and PTA are reported as part of the neurological assessment. This reflects the duration of Loss of Consciousness (LOC). Note: for patients admitted to hospital, the time to obeying commands is documented on hospital discharge: Hospital.HospDischargeTimeToObeyCommands
InjuryHx.LOCGCSSumDet Original 0 == None
1 == 1 point
2 == 2 or more points
88 == Unknown
LOC and PTA are reported as part of the neurological assessment. This reflects for the Loss of Consciousness (LOC) the GCS sum score deterioration within one hour after presentation.
InjuryHx.LOCLossOfConsciousness Original 0 == No
1 == Yes
3 == Suspected
88 == Unknown
LOC and PTA are reported as part of the neurological assessment. Loss of Consciousness (LOC) is a definite sign of TBI. However, TBI may be present without any LOC. Presence and duration is captured.
InjuryHx.LOCLucidInterval Original 0 == No
1 == Yes
88 == Unknown
LOC and PTA are reported as part of the neurological assessment. Lucid Interval is defined as a temporary improvement in a patient's condition after a traumatic brain injury, after which the condition deteriorates. A lucid interval is especially indicative of an epidural hematoma. An estimated 20 to 50% of patients with epidural hematoma experience such a lucid interval.
InjuryHx.LOCLucidIntervalHrs Original Lucid Interval is defined as a temporary improvement in a patient's condition after a traumatic brain injury, after which the condition deteriorates. This reflects the Number of hours after injury that secondary deterioration occurred (in case Lucid Interval = Yes)
InjuryHx.LOCLucidIntervalHrsUnk Original Lucid Interval is defined as a temporary improvement in a patient's condition after a traumatic brain injury, after which the condition deteriorates. This reflects if the Number of hours after injury that secondary deterioration occurred is Unknown (in case Lucid Interval = Yes).
InjuryHx.LOCPTA Original 0 == No
1 == Yes, ongoing
2 == Yes, resolved
3 == Suspected
88 == Unknown
LOC and PTA are reported as part of the neurological assessment. Post-traumatic amnesia (PTA) is the period after the injury that the patient cannot remember. In contrast to retrograde amnesia, the duration of PTA remains constant over time. To document presence/absence of PTA on discharge from the ER, the GOAT questionnaire is requested: Outcomes.GOATDate
InjuryHx.LOCPTADuration Original 0 == None
2 == <1 hour
5 == 1-24 hours
6 == 1-7 days
7 == 7-28 days
8 == 1-2 hours
9 == 2-4 hours
10 == 4-24 hours
11 == >1 day
28 == >28
77 == N/A (e.g. death)
88 == Unknown
LOC and PTA are reported as part of the neurological assessment. This variable is recorded only Only if PTA is yes. The duration of PTA reflects the severity of TBI. In patients with more sever TBI, the duration of PTA cannot be determined on presentation. For patients admitted to hospital, the duration of TBI in days is also captured on hospital discharge:.Hospital.HospDischPTADays
InjuryHx.LOCPTAReportedBy Original 1 == Patient
2 == Witness
3 == Retrospective assessment/ clinical interview
4 == Medical chart
5 == Not available
6 == Prospective assessment with PTA scale
LOC and PTA are reported as part of the neurological assessment. This reflects by whom PTA is reported.
InjuryHx.LOCPTAScale Original 1 == GOAT
2 == Westmead
3 == O-Log
4 == Nijmegen PTA scale
99 == Other
LOC and PTA are reported as part of the neurological assessment. In some centres, prospective assessment of amnesia (PTA) after TBI is performed using a dedicated scale. This variable documents the scale used.
InjuryHx.LOCReportedBy Original 1 == Self report
2 == Witness
3 == Clinical interview
4 == Medical chart
5 == Not available
LOC and PTA are reported as part of the neurological assessment. This variable reflects by whom LOC was reported.
InjuryHx.LOCRGA Original 0 == No
1 == Yes
88 == Unknown
This reflects presence or absence of retrograde amnesia during neurological assessment. Amnesia after injury is a sign of TBI. Retrograde amnesia is the period before the injury that the patient cannot remember. The duration of retrograde amnesia becomes shorter as the injury is longer ago. The duration of retrograde amnesia is therefore dependent on time after injury at which it was assessed.
InjuryHx.LOCRGADur Original 0 == None
1 == <30
2 == >= 30 minutes
88 == Unknown
This reflects the duration of retrograde amnesia is present during neurological assessment.
InjuryHx.LOCRGAReportBy Original 1 == Self report
2 == Witness
3 == Clinical interview
4 == Medical chart
5 == Not available
This reflects by whom Retrograde amnesia was reported if present during neurological assessment.
InjuryHx.LowerExtremitiesAIS Original 0 == 0 No Injury
1 == 1 Minor
2 == 2 Moderate
3 == 3 Serious
4 == 4 Severe
5 == 5 Critical
6 == 6 Unsurvivable
AIS score for Lower extremities as subdomain of Extremities and pelvic girdle. In the original AIS classification of injury severity, the grading is from 1 (minor) to 6 (unsurvivable). We added a score of 0 to designate absence of injuries.
InjuryHx.LowerExtremitiesDesc Original 1 == Femoral fracture
2 == Tibia plateau fracture
3 == Tibia fracture
4 == Ankle fracture
5 == Calcaneus fracture
6 == Metatarsal/tarsal fracture (toe fracture)
7 == Fibula fracture
Injury Description for the AIS score for Lower extremities as subdomain of Extremities and pelvic girdle.
InjuryHx.LumbarSpineAIS Original 0 == 0 No Injury
1 == 1 Minor
2 == 2 Moderate
3 == 3 Serious
4 == 4 Severe
5 == 5 Critical
6 == 6 Unsurvivable
AIS score for Lumbar spine as subdomain of Abdomen/Pelvic contents. In the original AIS classification of injury severity, the grading is from 1 (minor) to 6 (unsurvivable). We added a score of 0 to designate absence of injuries.
InjuryHx.LumbarSpineDesc Original 1 == Fracture
2 == Dislocation
3 == Sacral fracture
99 == Other
Injury description for AIS score for Lumbar spine as subdomain of Abdomen/Pelvic contents.
InjuryHx.NeuroAssmtsAVPU Original U == The patient is completely unresponsive
A == Patient is awake
V == Patient responds to verbal stimulation
P == The patient responds to painful stimulation
88 == Unknown
AVPU is scored as part of the neurological assessment on arrival to the ER. The AVPU scale (an acronym from "alert, voice, pain, unresponsive") is a system by which a health care professional can measure and record a patient's responsiveness, indicating their level of consciousness.
InjuryHx.PainScale Original During neurological assessment at arrival to ER an overall rating was recorded for pain intensity going from 0 (zero pain) to 100 (unbearable pain).
InjuryHx.PainScaleUnk 77 == Untestable
88 == Unknown
During neurological assessment at arrival to ER an overall rating was recorded for pain intensity going from 0 (zero pain) to 100 (unbearable pain). This variable reflects if the pain intensity was Untestable of Unknown.
InjuryHx.PelvicGirdleAIS Original 0 == 0 No Injury
1 == 1 Minor
2 == 2 Moderate
3 == 3 Serious
4 == 4 Severe
5 == 5 Critical
6 == 6 Unsurvivable
AIS score for Pelvic Girdle as subdomain of Extremities and pelvic girdle. In the original AIS classification of injury severity, the grading is from 1 (minor) to 6 (unsurvivable). We added a score of 0 to designate absence of injuries.
InjuryHx.PelvicGirdleDesc 1 == Pelvic fracture
2 == Hip fracture
3 == Hip dislocation
Injury description for AIS score for Pelvic Girdle as subdomain of Extremities and pelvic girdle.
InjuryHx.PreHospAssmtConditions 0 == No sedation or paralysis
1 == Sedated
2 == Paralyzed
3 == Temporary stop of sedation/paralysis
4 == Reversal of sedation/paralysis
5 == Active reversal (pharmacologic) of sedation/paralysis
99 == Other
Neurological assessment (GCS and pupils) was recorded for the scene of accident, the first hospital (if applicable), the Arrival to ER of the study hospital and post-stabilization. This describes the condition under which the GCS was assessed for the assessment at Scene Of Accident.
InjuryHx.PresArrivalMethod 1 == Ambulance
2 == Helicopter
3 == Medical mobile team
4 == Walk in or drop off
99 == Other
Reflects the mode of transportation used to transport the subject from the scene of accident to the hospital.
InjuryHx.PresCirculationTreatmentCPR The status of Airway, Breathing and Circulation on scene are documented. This records Emergency care treatment on scene performed with regard to Circulation: CPR (Cardio-pulmonary resuscitation) ER arrival status is documented at: InjuryHX.EDArrivalCirculation
InjuryHx.PresCirculationTreatmentIVFluids The status of Airway, Breathing and Circulation on scene are documented. This records Emergency care treatment on scene performed with regard to Circulation: IV Fluids ER arrival status is documented at: InjuryHX.EDArrivalCirculation
InjuryHx.PresCirculationTreatmentNone The status of Airway, Breathing and Circulation on scene are documented. This records Emergency care treatment on scene performed with regard to Circulation: None ER arrival status is documented at: InjuryHX.EDArrivalCirculation
InjuryHx.PresCirculationTreatmentUnknown The status of Airway, Breathing and Circulation on scene are documented. This records Emergency care treatment on scene performed with regard to Circulation: Unknown ER arrival status is documented at: InjuryHX.EDArrivalCirculation
InjuryHx.PresCTBrain 0 == No
1 == Yes
88 == Unknown
In case of a Secondary referral (see InjuryHx.PresTBIref), details of procedures performed at the first hospital (not study hospital) were recorded. This reflects if a CT Brain was performed in the first hospital (not study hospital).
InjuryHx.PresEmergencyCare Original 0 == None
1 == Untrained person (by stander)
2 == Trainer/coach
3 == Military, non-medic
4 == Paramedic
5 == Nurse
6 == Physician
7 == Medical rescue team
99 == Other
Reflects if and by whom emergency medical care was given at the scene of accident (highest level of assistance)
InjuryHx.PresEmergencyCareIntubation Original 0 == No
1 == Yes
88 == Unknown
Reflects if intubation was performed on scene.
InjuryHx.PresEmergencyCareSuppOxygen 0 == No
1 == Yes
88 == Unknown
Reflects if supplemental oxygen was given on scene.
InjuryHx.PresEmergencyCareVentilation Original 0 == No
1 == Yes
88 == Unknown
Reflects if Mechanical Ventilation was done on scene.
InjuryHx.PresEmergencyServiceAmbuBasic Original Reflects type of Emergency service involved at accident scene --> Ambulance (basic EMT­B)
InjuryHx.PresEmergencyServiceAmbuSpec Original Reflects type of Emergency service involved at accident scene --> Ambulance specialized (EMT­P)
InjuryHx.PresEmergencyServiceFirefighter Original Reflects type of Emergency service involved at accident scene --> Firefighter
InjuryHx.PresEmergencyServiceHelicopter Original Reflects type of Emergency service involved at accident scene --> Helicopter
InjuryHx.PresEmergencyServiceNone Original Reflects type of mergency service involved at accident scene --> None
InjuryHx.PresEmergencyServicePolice Original Reflects type of Emergency service involved at accident scene --> Police
InjuryHx.PresERExtracranialSurg 0 == No
1 == Yes
88 == Unknown
In case of a Secondary referral (see InjuryHx.PresTBIref), details of procedures performed at the first hospital (not study hospital) were recorded. This reflects if Emergency intracranial surgery was performed in the first hospital (not study hospital).
InjuryHx.PresERIntracranialSurg Original 0 == No
1 == Yes
88 == Unknown
In case of a Secondary referral (see InjuryHx.PresTBIref), details of procedures performed at the first hospital (not study hospital) were recorded. This reflects if Emergency extracranial surgery was performed in the first hospital (not study hospital). Surgical procedures decided on to perform directly on arrival to the Study hospital are recorded within InjuryHx.EmergSurgInterventionsIntraCran.
InjuryHx.PresFHospDate In case of a Secondary referral (see InjuryHx.PresTBIref), details of procedures performed at the first hospital (not study hospital) were recorded. First hospital is defined as the initial hospital to which the patient was brought before being transferred to Study hospital. This reflects Date of arrival to first hospital.
InjuryHx.PresFHospTime In case of a Secondary referral (see InjuryHx.PresTBIref), details of procedures performed at the first hospital (not study hospital) were recorded. First hospital is defined as the initial hospital to which the patient was brought before being transferred to Study hospital. This reflects Time of arrival to first hospital.
InjuryHx.PresFirstOnSceneDate Reflects Times at accident scene --> First on scene --> Date
InjuryHx.PresFirstOnSceneDepartUnknownTime 77 == N/A if emergency service=none
88 == Unknown
Reflects Times at accident scene --> Departure time -->N/A (if emergency service=none) or when Unknown
InjuryHx.PresFirstOnSceneDepartureDate Reflects Times at accident scene --> Departure time --> Date
InjuryHx.PresFirstOnSceneDepartureTime Reflects Times at accident scene --> Departure time --> Time
InjuryHx.PresFirstOnSceneTime Reflects Times at accident scene --> First on scene --> Time
InjuryHx.PresFirstOnSceneUnknownTime 77 == N/A if emergency service=none
88 == Unknown
Reflects if Time of arrival of EMS to incident scene = unknown or N/A (f.e. if no EMS involved)
InjuryHx.PresIntubation 0 == No
1 == Yes
88 == Unknown
In case of a Secondary referral (see InjuryHx.PresTBIref), details of procedures performed at the first hospital (not study hospital) were recorded. This reflects if the subject was intubated at first hospital (not study hospital).
InjuryHx.PresSTHospDate Reflects the Date of arrival to study hospital
InjuryHx.PresSTHospTime Reflects Time of arrival to study hospital
InjuryHx.PresTBIRef 1 == Primary
2 == Secondary
Reflects if the subject was transported from the scene of accident immediately to the study hospital (primary referral) or if secondary referral occurred from a first hospital to the Study hospital.
InjuryHx.PupilsBaselineDerived Derived 0 - Both reacting
1 - One reacting (other pupil is either unreactive, missing or untestable)
2 - Both unreacting
This is a derived variable calculated centrally. Number of unreactive pupils for baseline risk adjustment with missing values imputed using IMPACT methodology- take Poststabilisation value and if absent work back in time towards prehospital values until non-missing value found. Untestable pupil ignored: I.e. 1 reactive + 1 untestable = 1 reactive (this assumption applies only to a small proportion of the data). RECOMMENDED FOR BASELINE RISK ADJUSTMENT.
InjuryHx.PupilsNonSymmetric Derived Pupil symmetry derived variable calculated from (GCSFirstHospPupilSymmetry,EDArrPupilSymmetry,GCSPreHospPupilSymmetry,EDDischPupilSymmetry,PupilsNonSymmetric)
InjuryHx.SedativeCurrentUse 0 == No
1 == Yes
88 == Unknown
On presentation the behavioral history of the patient was recorded. This reflects if in the past three months the subjects used sedatives or sleeping pills.
InjuryHx.SedativePriorUse 0 == No
1 == Yes
88 == Unknown
On presentation the behavioral history of the patient was recorded. This reflects his past use of Sedatives or sleeping pill.
InjuryHx.SedativePriorUseDuration Original On presentation the behavioral history of the patient was recorded. This reflects the number sof years of his past use sedatives (if applicable).
InjuryHx.SympSkullFract 0 == No
1 == Yes
88 == Unknown
During neurological assessment at arrival in the ER, Clinical signs of skull base fracture (e.g. raccoon eyes, battle sign, hemotympanun, CSF otorrhea, CRF rhinorrhea, bleeding from ear) were recorded.
InjuryHx.SympVomiting 0 == No
1 == Once
2 == More than once
88 == Unknown
During neurological assessment at arrival in the ER, Vomiting was recorded.
InjuryHx.ThoracicSpineAIS Original 0 == 0 No Injury
1 == 1 Minor
2 == 2 Moderate
3 == 3 Serious
4 == 4 Severe
5 == 5 Critical
6 == 6 Unsurvivable
AIS score for the Thoracic Spine as subdomain of Thorax/Chest. In the original AIS classification of injury severity, the grading is from 1 (minor) to 6 (unsurvivable). We added a score of 0 to designate absence of injuries.
InjuryHx.ThoracicSpineDesc 1 == Fracture
2 == Dislocation
Injury description for the AIS of Thoracic spine as subdomain of Thorax/Chest
InjuryHx.ThoraxChestAIS Original 0 == 0 No Injury
1 == 1 Minor
2 == 2 Moderate
3 == 3 Serious
4 == 4 Severe
5 == 5 Critical
6 == 6 Unsurvivable
AIS score for the Thorax/Chest region. In the original AIS classification of injury severity, the grading is from 1 (minor) to 6 (unsurvivable). We added a score of 0 to designate absence of injuries.
InjuryHx.ThoraxChestDesc 1 == Rib fracture
2 == Lung contusion
3 == Cardiac contusion
4 == Aorta dissection
5 == Pneumo-thorax
6 == Hemato-thorax
99 == Other
Injury description for the AIS of the Thorax/Chest region.
InjuryHx.TobcoCurntUseInd 0 == No
1 == Yes
88 == Unknown
On presentation the behavioral history of the patient was recorded. This reflects his use in the past three months of Tobacco products (cigarettes, cigars, pipe, chewing tobacco, etc.)
InjuryHx.TobcoPriorUseInd 0 == No
1 == Yes
88 == Unknown
The form "Behavioral History" captures information on past and current use of alcohol, tobacco, sedatives/sleeping pills, cannabis and other recreational drugs. Use is differentiated as "Past user" (eg stopped) versus "use in the past 3 months. Note: These variables do not reflect use of these substances at the time of injury.
InjuryHx.TobcoUseDur Original On presentation the behavioral history of the patient was recorded. This reflects the number of years of his past use of Tobacco (if applicable).
InjuryHx.TotalISS Calculated The Injury Severity Score is calculated as the sum of the squares of the the 3 body regions with the highest AIS score. The max score for the ISS = 75. If any body region AIS is assigned a score of "6", the ISS is automatically set to 75 (highest score). In the calculation of the ISS, only the 6 main body regions are taken into consideration.
InjuryHx.UpperExtremitiesAIS Original 0 == 0 No Injury
1 == 1 Minor
2 == 2 Moderate
3 == 3 Serious
4 == 4 Severe
5 == 5 Critical
6 == 6 Unsurvivable
AIS score of the Upper extremities as subdomain of Extremities and pelvic girdle. In the original AIS classification of injury severity, the grading is from 1 (minor) to 6 (unsurvivable). We added a score of 0 to designate absence of injuries.
InjuryHx.UpperExtremitiesDesc Original 1 == Humerus fracture
2 == Radial and/or ulnar fracture
3 == Dislocation
4 == Hand
5 == Finger
Injury description for the AIS score of the Upper extremities as subdomain of Extremities and pelvic girdle.
Labs.DLA10Extem Original Only applicable to sites doing ROTEM studies. ROTEM --> A10 --> EXTEM
Labs.DLA10Fibtem Original Only applicable to sites doing ROTEM studies. ROTEM --> A10 --> FIBTEM
Labs.DLA10NotDone Original Only applicable to sites doing ROTEM studies. ROTEM --> A10 --> Not Done
Labs.DLA5Extem Original Only applicable to sites doing ROTEM studies. ROTEM --> A5 --> EXTEM
Labs.DLA5Fibtem Original Only applicable to sites doing ROTEM studies ROTEM --> A5 --> FIBTEM
Labs.DLA5NotDone Original Only applicable to sites doing ROTEM studies. ROTEM --> A5 --> Not Done
Labs.DLaAngleExtem Original Only applicable to sites doing ROTEM studies. ROTEM --> α-angle --> EXTEM
Labs.DLaAngleFibtem Original Only applicable to sites doing ROTEM studies. ROTEM --> α-angle --> FIBTEM
Labs.DLaAngleNotDone Original Only applicable to sites doing ROTEM studies. ROTEM --> α-angle --> Not Done
Labs.DLACT Original Only applicable to sites doing ROTEM/TEG studies. TEG --> ACT (rapid TEG only)
Labs.DLACTNotDone Original Only applicable to sites doing ROTEM/TEG studies. TEG --> ACT --> Not Done
Labs.DLADPAggreg Original Only applicable to sites doing multiplate studies. MULTIPLATE TEST --> ADP Test --> Aggregation
Labs.DLADPAUC Original Only applicable to sites doing multiplate studies. MULTIPLATE TEST --> ADP Test --> AUC (AU*min)
Labs.DLADPAUCU Original Only applicable to sites doing multiplate studies MULTIPLATE TEST --> ADP Test --> AUC (U)
Labs.DLADPVelocity Original Only applicable to sites doing multiplate studies. MULTIPLATE TEST --> ADP Test --> Velocity
Labs.DLAlatSgptNotDone Original BLOOD CHEMISTRY --> ALAT/SGPT ( Alanine Aminotrasferase) --> Not done
Labs.DLAlatSgptOther Original Preferred unit for ALAT/SGPT was U/L. When sites used another unit, the value was recorded here.
Labs.DLAlatSgptOtherUnit Original Preferred unit for ALAT/SGPT was U/L. When sites used another unit, the other unit was recorded here.
Labs.DLAlatSgptUL Original BLOOD CHEMISTRY --> ALAT/SGPT Recorded in "preferred" units (U/L)
Labs.DLAlbumingL Original BLOOD CHEMISTRY --> Albumin Recorded in "preferred" units (g/dL)
Labs.DLAlbuminNotDone Original BLOOD CHEMISTRY --> Albumin --> Not done
Labs.DLAlbuminOther Original Preferred unit for Albumin was g/L. When sites used another unit, the value was recorded here.
Labs.DLAlbuminOtherUnit Original Preferred unit for Albumin was g/L. When sites used another unit, the other unit was recorded here.
Labs.DLAlkalinePhosphataseNotDone Original BLOOD CHEMISTRY --> Alkaline Phosphatase --> Not done
Labs.DLAlkalinePhosphataseOther Original Preferred unit for Alkaline Phosphatase was U/L. When sites used another unit, the value was recorded here.
Labs.DLAlkalinePhosphataseOtherUnit Original Preferred unit for Alkaline Phosphatase was U/L. When sites used another unit, the other unit was recorded here.
Labs.DLAlkalinePhosphataseUL Original BLOOD CHEMISTRY --> Alkaline Phosphatase Recorded in "preferred" units (U/L)
Labs.DLAmylaseNotDone Original BLOOD CHEMISTRY --> Amylase --> Not done
Labs.DLAmylaseOther Original Preferred unit for Amylase was U/L. When sites used another unit, the value was recorded here.
Labs.DLAmylaseOtherUnit Original Preferred unit for Amylase was U/L. When sites used another unit, the other unit was recorded here.
Labs.DLAmylaseUL Original BLOOD CHEMISTRY --> Amylase Recorded in "preferred" units (U/L)
Labs.DLaPttNotDone Original HAEMATOLOGY --> Activated thromboplastine time (aPTT) --> Not done
Labs.DLaPttOther Original Preferred unit for aPTT was sec. When sites used another unit, the value was recorded here.
Labs.DLaPttOtherUnit Original Preferred unit for aPTT was sec. When sites used another unit, the other unit was recorded here.
Labs.DLaPttsec Original HAEMATOLOGY --> Activated thromboplastine time (aPTT) Recorded in "preferred" units (sec.)
Labs.DLAsatSgotNotDone Original BLOOD CHEMISTRY --> ASAT/SGOT --> Not done
Labs.DLAsatSgotOther Original Preferred unit for ASAT/SGOT was U/L. When sites used another unit, the value was recorded here.
Labs.DLAsatSgotOtherUnit Original Preferred unit for ASAT/SGOT was U/L. When sites used another unit, the other unit was recorded here.
Labs.DLAsatSgotUL Original BLOOD CHEMISTRY --> ASAT/SGOT Recorded in "preferred" units (U/L)
Labs.DLASPIAggreg Original Only applicable to sites doing multiplate studies. MULTIPLATE TEST --> ASPI Test --> Aggregation
Labs.DLASPIAUC Original Only applicable to sites doing multiplate studies
Labs.DLASPIAUCU Original Only applicable to sites doing multiplate studies MULTIPLATE TEST --> ASPI Test --> AUC (U)
Labs.DLASPIVelocity Original Only applicable to sites doing multiplate studies MULTIPLATE TEST --> ASPI Test --> Velocity (AU*min)
Labs.DLBloodChemDone Original Reflects if Blood chemistry was done.
Labs.DLCalciummmolL Original BLOOD CHEMISTRY --> Calcium Recorded in "preferred" units (mmol/L)
Labs.DLCalciumNotDone Original BLOOD CHEMISTRY --> Calcium --> Not done
Labs.DLCalciumOther Original Preferred unit for Calcium was mmol/L. When sites used another unit, the value was recorded here.
Labs.DLCalciumOtherUnit Original Preferred unit for Calcium was mmol/L. When sites used another unit, the other unit was recorded here.
Labs.DLCFTExtem Original Only applicable to sites doing ROTEM studies. ROTEM --> CFT --> EXTEM
Labs.DLCFTFibtem Original Only applicable to sites doing ROTEM studies. ROTEM --> CFT --> FIBTEM
Labs.DLCFTNotDone Original Only applicable to sites doing ROTEM studies. ROTEM --> CFT --> Not Done
Labs.DLCL30 Original Only applicable to sites doing ROTEM/TEG studies. TEG --> CL30
Labs.DLCL30NotDone Original Only applicable to sites doing ROTEM/TEG studies. TEG --> CL30 --> Not Done
Labs.DLCL60 Original Only applicable to sites doing ROTEM/TEG studies. TEG --> CL60
Labs.DLCL60NotDone Original Only applicable to sites doing ROTEM/TEG studies. TEG --> CL60 --> Not Done
Labs.DLCLTExtem Original Only applicable to sites doing ROTEM studies ROTEM --> CLT --> EXTEM
Labs.DLCLTFibtem Original Only applicable to sites doing ROTEM studies ROTEM --> CLT --> FIBTEM
Labs.DLCLTNotDone Original Only applicable to sites doing ROTEM studies ROTEM --> CLT --> Not Done
Labs.DLCOLAggreg Original Only applicable to sites doing multiplate studies MULTIPLATE TEST --> COL Test --> Aggregation
Labs.DLCOLAUC Original Only applicable to sites doing multiplate studies MULTIPLATE TEST --> COL Test --> AUC (AU*min)
Labs.DLCOLAUCU Original Only applicable to sites doing multiplate studies MULTIPLATE TEST --> COL Test --> AUC (U)
Labs.DLCOLVelocity Original Only applicable to sites doing multiplate studies MULTIPLATE TEST --> COL Test --> Velocity (AU*min)
Labs.DLCreatinineNotDone Original BLOOD CHEMISTRY --> Creatinine --> Not done
Labs.DLCreatinineOther Original Preferred unit for Creatinine was µmol/L. When sites used another unit, the value was recorded here.
Labs.DLCreatinineOtherUnit Original Preferred unit for Creatinine was µmol/L. When sites used another unit, the other unit was recorded here.
Labs.DLCreatinineumolL Original BLOOD CHEMISTRY --> Creatinine Recorded in "preferred" units (µmol/L)
Labs.DLCRPmgL Original HAEMATOLOGY --> C-reactive protein (CRP) Recorded in "preferred" units (mg/L)
Labs.DLCRPNotDone Original HAEMATOLOGY --> C-reactive protein (CRP) --> Not done
Labs.DLCRPOther Original Preferred unit for CRP was mg/L. When sites used another unit, the value was recorded here.
Labs.DLCRPOtherUnit Original Preferred unit for CRP was mg/L. When sites used another unit, the other unit was recorded here.
Labs.DLCTExtem Original Only applicable to sites doing ROTEM studies ROTEM --> CT --> EXTEM
Labs.DLCTFibtem Original Only applicable to sites doing ROTEM studies ROTEM --> CT --> FIBTEM
Labs.DLCTNotDone Original Only applicable to sites doing ROTEM studies ROTEM --> CT --> Not Done
Labs.DLDate Original Date of labs
Labs.DLDdimersNotDone Original HAEMATOLOGY --> D-dimers --> Not done
Labs.DLDdimersOther Original Preferred unit for D-dimers was µg/L. When sites used another unit, the value was recorded here.
Labs.DLDdimersOtherUnit Original Preferred unit for D-dimers was µg/L. When sites used another unit, the other unit was recorded here.
Labs.DLDdimersugL Original HAEMATOLOGY --> D-dimers Recorded in "preferred" units ( µg/L)
Labs.DLEosinophilsNotDone Original HAEMATOLOGY --> Eosinophils --> Not done
Labs.DLEosinophilsOther Original Preferred unit for Eosinophils was %. When sites used another unit, the value was recorded here.
Labs.DLEosinophilsOtherUnit Original Preferred unit for Eosinophils was %. When sites used another unit, the other unit was recorded here.
Labs.DLEosinophilspct Original HAEMATOLOGY --> Eosinophils Recorded in "preferred" units (%)
Labs.DLEPL Original Only applicable to sites doing TEG/ROTEM studies TEG --> EPL
Labs.DLEPLNotDone Original Only applicable to sites doing TEG/ROTEM studies TEG --> EPL--> Not Done
Labs.DLFibrinogenmgdL Original HAEMATOLOGY --> Fibrinogen Recorded in "preferred" units (mg/dL)
Labs.DLFibrinogenNotDone Original HAEMATOLOGY --> Fibrinogen --> Not done
Labs.DLFibrinogenOther Original Preferred unit for Fibrinogen was mg/dL. When sites used another unit, the value was recorded here.
Labs.DLFibrinogenOtherUnit Original Preferred unit for Fibrinogen was mg/dL. When sites used another unit, the other unit was recorded here.
Labs.DLGlucosemmolL Original BLOOD CHEMISTRY --> Glucose Recorded in "preferred" units (mmol/L)
Labs.DLGlucoseNotDone Original BLOOD CHEMISTRY --> Glucose --> Not done
Labs.DLGlucoseOther Original Preferred unit for Glucose was mmol/L. When sites used another unit, the value was recorded here.
Labs.DLGlucoseOtherUnit Original Preferred unit for Glucose was mmol/L. When sites used another unit, the other unit was recorded here.
Labs.DLHaematologyDone Original Reflects if Haematology labs was done
Labs.DLHematocritNotDone Original HAEMATOLOGY --> Hematocrit --> Not done
Labs.DLHematocritOther Original Preferred unit for Hematocrit was %. When sites used another unit, the value was recorded here.
Labs.DLHematocritOtherUnit Original Preferred unit for Hematocrit was %. When sites used another unit, the other unit was recorded here.
Labs.DLHematocritpct Original HAEMATOLOGY --> Hematocrit Recorded in "preferred" units (%)
Labs.DLHemoglobingdL Original HAEMATOLOGY --> Hemoglobin Recorded in "preferred" units (g/dL)
Labs.DLHemoglobinNotDone Original HAEMATOLOGY --> Hemoglobin --> Not done
Labs.DLHemoglobinOther Original Preferred unit for Hemoglobin was g/dL. When sites used another unit, the value was recorded here.
Labs.DLHemoglobinOtherUnit Original Preferred unit for Hemoglobin was g/dL. When sites used another unit, the other unit was recorded here.
Labs.DLInr Original HAEMATOLOGY --> INR
Labs.DLInrNotDone Original HAEMATOLOGY --> INR --> Not done
Labs.DLInrOther Original INR results if other units used than standard
Labs.DLInrOtherUnit Original INR results if other units used than standard
Labs.DLK Original Only applicable to sites doing TEG/ROTEM studies TEG --> K
Labs.DLKNotDone Original Only applicable to sites doing TEG/ROTEM studies TEG --> K--> Not Done
Labs.DLLabsNotDone Original Reflects when hospital labs were not done
Labs.DLLabsNotDoneOther Original Specifies the reason why hospital labs were not done
Labs.DLLdhNotDone Original BLOOD CHEMISTRY --> LDH (Lactate Dehydrogenase) --> Not done
Labs.DLLdhOther Original Preferred unit for LDH was U/L. When sites used another unit, the value was recorded here.
Labs.DLLdhOtherUnit Original Preferred unit for LDH was U/L. When sites used another unit, the other unit was recorded here.
Labs.DLLdhUL Original BLOOD CHEMISTRY --> LDH (Lactate Dehydrogenase) Recorded in "preferred" units (U/L)
Labs.DLLY30Extem Original Only applicable to sites doing ROTEM studies ROTEM --> LY30 --> EXTEM
Labs.DLLY30Fibtem Original Only applicable to sites doing ROTEM studies ROTEM --> LY30 --> FIBTEM
Labs.DLLY30NotDone Original Only applicable to sites doing ROTEM studies ROTEM --> LY30 --> Not Done
Labs.DLLY60Extem Original Only applicable to sites doing ROTEM studies ROTEM --> LY60 --> EXTEM
Labs.DLLY60Fibtem Original Only applicable to sites doing ROTEM studies ROTEM --> LY60 --> FIBTEM
Labs.DLLY60NotDone Original Only applicable to sites doing ROTEM studies ROTEM --> LY60 --> Not Done
Labs.DLLymphocytesNotDone Original HAEMATOLOGY --> Lymphocytes --> Not done
Labs.DLLymphocytesOther Original Preferred unit for Lymphocytes was %. When sites used another unit, the value was recorded here.
Labs.DLLymphocytesOtherUnit Original Preferred unit for Lymphocytes was %. When sites used another unit, the other unit was recorded here.
Labs.DLLymphocytespct Original HAEMATOLOGY --> Lymphocytes Recorded in "preferred" units (%)
Labs.DLMA Original Only applicable to sites doing TEG/ROTEM studies TEG --> MA
Labs.DLMagnesiummmolL Original BLOOD CHEMISTRY --> Magnesium Recorded in "preferred" units (mmol/L)
Labs.DLMagnesiumNotDone Original BLOOD CHEMISTRY --> Magnesium --> Not done
Labs.DLMagnesiumOther Original Preferred unit for Magnesium was mmol/L. When sites used another unit, the value was recorded here.
Labs.DLMagnesiumOtherUnit Original Preferred unit for Magnesium was mmol/L. When sites used another unit, the other unit was recorded here.
Labs.DLMANotDone Original Only applicable to sites doing TEG/ROTEM studies TEG --> MA --> Not Done
Labs.DLMCFExtem Original Only applicable to sites doing ROTEM studies ROTEM --> MCF --> EXTEM
Labs.DLMCFFibtem Original Only applicable to sites doing ROTEM studies ROTEM --> MCF --> FIBTEM
Labs.DLMCFNotDone Original Only applicable to sites doing ROTEM studies ROTEM --> MCF --> Not Done
Labs.DLMCFtExtem Original Only applicable to sites doing ROTEM studies ROTEM --> MCF-t --> EXTEM
Labs.DLMCFtFibtem Original Only applicable to sites doing ROTEM studies ROTEM --> MCF-t --> FIBTEM
Labs.DLMCFtNotDone Original Only applicable to sites doing ROTEM studies ROTEM --> MCF-t --> Not Done
Labs.DLMLExtem Original Only applicable to sites doing ROTEM studies ROTEM --> ML --> EXTEM
Labs.DLMLFibtem Original Only applicable to sites doing ROTEM studies ROTEM --> ML --> FIBTEM
Labs.DLMLNotDone Original Only applicable to sites doing ROTEM studies ROTEM --> ML --> Not Done
Labs.DLMultiplateDone Original Reflects if Multiplate was done - Only in selected sites
Labs.DLNeutrophilsNotDone Original HAEMATOLOGY --> Neutrophils --> Not done
Labs.DLNeutrophilsOther Original Preferred unit for Neutrophils was %. When sites used another unit, the value was recorded here.
Labs.DLNeutrophilsOtherUnit Original Preferred unit for Neutrophils was %. When sites used another unit, the other unit was recorded here.
Labs.DLNeutrophilspct Original HAEMATOLOGY --> Neutrophils Recorded in "preferred" units (%)
Labs.DLPlatelet10_5L Original HAEMATOLOGY --> Platelet Recorded in "preferred" units (X10^9/L or X10^3/µL)
Labs.DLPlateletNotDone Original HAEMATOLOGY --> Platelet --> Not done
Labs.DLPlateletOther Original Preferred unit for Platelet was X10^9/L or X10^3/μL. When sites used another unit, the value was recorded here.
Labs.DLPlateletOtherUnit Original Preferred unit for Platelet was X10^9/L or X10^3/μL. When sites used another unit, the other unit was recorded here.
Labs.DLPotassiummmolL Original BLOOD CHEMISTRY --> Potassium Recorded in "preferred" units (mmol/L)
Labs.DLPotassiumNotDone Original BLOOD CHEMISTRY --> Potassium --> Not done
Labs.DLPotassiumOther Original Preferred unit for Potassium was mmol/L. When sites used another unit, the value was recorded here.
Labs.DLPotassiumOtherUnit Original Preferred unit for Potassium was mmol/L. When sites used another unit, the other unit was recorded here.
Labs.DLProthrombineTimeNotDone Original HAEMATOLOGY --> Prothrombine Time --> Not done
Labs.DLProthrombineTimeOther Original Preferred unit for Prothrombine Time was sec. When sites used another unit, the value was recorded here.
Labs.DLProthrombineTimeOtherUnit Original Preferred unit for Prothrombine Time was sec. When sites used another unit, the other unit was recorded here.
Labs.DLProthrombineTimeSec Original HAEMATOLOGY --> Prothrombine Time Recorded in "preferred" units (sec.)
Labs.DLR Original Only applicable to sites doing TEG/ROTEM studies TEG --> R
Labs.DLRISTOAggreg Original Only applicable to sites doing multiplate studies MULTIPLATE TEST --> RISTO Test --> Aggregation
Labs.DLRISTOAUC Original Only applicable to sites doing multiplate studies MULTIPLATE TEST --> RISTO Test --> AUC (AU*min)
Labs.DLRISTOAUCU Original Only applicable to sites doing multiplate studies MULTIPLATE TEST --> RISTO Test --> AUC (U)
Labs.DLRISTOVelocity Original Only applicable to sites doing multiplate studies MULTIPLATE TEST --> RISTO Test --> Velocity (AU*min)
Labs.DLRNotDone Original Only applicable to sites doing TEG studies TEG --> R --> Not Done
Labs.DLROTEMDone Original Reflects if ROTEM was done - Only applicable to sites doing ROTEM tests
Labs.DLS100BNotDone Original BLOOD CHEMISTRY --> S100B --> Not done
Labs.DLS100BOther Original Preferred unit for S100B was µg/L. When sites used another unit, the value was recorded here.
Labs.DLS100BOtherUnit Original Preferred unit for S100B was µg/L. When sites used another unit, the other unit was recorded here.
Labs.DLS100BugL Original BLOOD CHEMISTRY --> S100B Recorded in "preferred" units (µg/L)
Labs.DLSodiummmolL Original BLOOD CHEMISTRY --> Sodium Recorded in "preferred" units (mmol/L)
Labs.DLSodiumNotDone Original BLOOD CHEMISTRY --> Sodium --> Not done
Labs.DLSodiumOther Original Preferred unit for Sodium mmol/L. When sites used another unit, the value was recorded here.
Labs.DLSodiumOtherUnit Original Preferred unit for Sodium mmol/L. When sites used another unit, the other unit was recorded here.
Labs.DLTEGA10 Original Only applicable for sites doing TEG TEG --> A10
Labs.DLTEGA10NotDone Original Only applicable for sites doing TEG TEG --> A10 --> Not Done
Labs.DLTEGA5 Original Only applicable for sites doing TEG TEG --> A5
Labs.DLTEGA5NotDone Original Only applicable for sites doing TEG TEG --> A5 --> Not Done
Labs.DLTEGaAngle Original Only applicable for sites doing TEG TEG --> α-angle
Labs.DLTEGaAngleNotDone Original Only applicable for sites doing TEG TEG --> α-angle --> Not Done
Labs.DLTEGDone Original Reflects if TEG was done - Only applicable for selected sites doing TEG
Labs.DLTEGType Original Reflects type of TEG done - Only applicable for selected sites doing TEG
Labs.DLTime Original Time of labs
Labs.DLTMA Original Only applicable for sites doing TEG TEG --> TMA
Labs.DLTMANotDone Original Only applicable for sites doing TEG TEG --> TMA --> Not Done
Labs.DLTotalBilirubinNotDone Original BLOOD CHEMISTRY --> Total Bilirubin --> Not done
Labs.DLTotalBilirubinOther Original Preferred unit for Total Bilirubin was µmol/L. When sites used another unit, the value was recorded here.
Labs.DLTotalBilirubinOtherUnit Original Preferred unit for Total Bilirubin was µmol/L. When sites used another unit, the other unit was recorded here.
Labs.DLTotalBilirubinumolL Original BLOOD CHEMISTRY --> Total Bilirubin Recorded in "preferred" units (µmol/L)
Labs.DLToxScreen Original Toxic Drug Screen Result Only if performed as part of clinical routine
Labs.DLToxScreenDone Original Reflects if Toxic Drug Screen was done. Only if performed as part of clinical routine.
Labs.DLToxScreenPosAmphet Original Reflects if Toxic Drug Screen was positive for Amphetamines. Only if performed as part of clinical routine.
Labs.DLToxScreenPosBarb Original Reflects if Toxic Drug Screen was positive for Barbiturates. Only if performed as part of clinical routine.
Labs.DLToxScreenPosBenzo Original Reflects if Toxic Drug Screen was positive for Benzodiazepines. Only if performed as part of clinical routine.
Labs.DLToxScreenPosCannabis Original Reflects if Toxic Drug Screen was positive for Cannabinoids. Only if performed as part of clinical routine.
Labs.DLToxScreenPosCocaine Original Reflects if Toxic Drug Screen was positive for Cocaine. Only if performed as part of clinical routine.
Labs.DLToxScreenPosMeth Original Reflects if Toxic Drug Screen was positive for Methadone. Only if performed as part of clinical routine.
Labs.DLToxScreenPosMethaqual Original Reflects if Toxic Drug Screen was positive for Methaqualone. Only if performed as part of clinical routine.
Labs.DLToxScreenPosOpiate Original Reflects if Toxic Drug Screen was positive for Opiates. Only if performed as part of clinical routine.
Labs.DLToxScreenPosOther Original Reflects if Toxic Drug Screen was positive for Other drugs than the predefined list. Only if performed as part of clinical routine.
Labs.DLToxScreenPosOtherTxt Original Specifies for which drugs, if Toxic Drug Screen was positive for Other drugs than the predefined list. Only if performed as part of clinical routine.
Labs.DLToxScreenPosPhency Original Reflects if Toxic Drug Screen was positive for Phencyclidine. Only if performed as part of clinical routine.
Labs.DLToxScreenType Original Serum
Urine
Specifies the type of sample, Urine or Serum, if Toxic Drug Screen was performed. Only if performed as part of clinical routine.
Labs.DLTRAPAggreg Original Only applicable to sites doing multiplate studies. MULTIPLATE TEST --> TRAP Test --> Aggregation
Labs.DLTRAPAUC Original Only applicable to sites doing multiplate studies. MULTIPLATE TEST --> TRAP Test --> AUC (AU*min)
Labs.DLTRAPAUCU Original Only applicable to sites doing multiplate studies. MULTIPLATE TEST --> TRAP Test --> AUC (U)
Labs.DLTRAPVelocity Original Only applicable to sites doing multiplate studies. MULTIPLATE TEST --> TRAP Test --> Velocity (AU*min)
Labs.DLTTL Original Only applicable to sites doing TEG studies TEG --> TTL
Labs.DLTTLNotDone Original Only applicable to sites doing TEG studies TEG --> TTL --> Not Done
Labs.DLUreammolL Original BLOOD CHEMISTRY --> Urea Recorded in "preferred" units (mmol/L)
Labs.DLUreaNotDone Original BLOOD CHEMISTRY --> Urea --> Not done
Labs.DLUreaOther Original Preferred unit for Urea was mmol/L. When sites used another unit, the value was recorded here.
Labs.DLUreaOtherUnit Original Preferred unit for Urea was mmol/L. When sites used another unit, the other unit was recorded here.
Labs.DLWhiteBloodCellNotDone Original HAEMATOLOGY --> White blood cell --> Not done
Labs.DLWhiteBloodCellOther Original Preferred unit for White Blood Cell was X10^9/L or X10^3/μL. When sites used another unit, the value was recorded here.
Labs.DLWhiteBloodCellOtherUnit Original Preferred unit for White Blood Cell was X10^9/L or X10^3/μL. When sites used another unit, the other unit was recorded here.
Labs.DLWhiteBloodCellpct Original HAEMATOLOGY --> White blood cell Recorded in "preferred" units (X10^9/L or X10^3/μL)
LabSampling.LSBiomarkersCollctnDate Original This reflects the biomarker sampling collection date. Protein biomarker sampling was planned in all subjects. 1 x 9ml blood sample was collected in a serum separator tube. After 45 minutes (±15) of coagulation at room temperature, it is centrifuged at 1500g for 10 minutes, 8 x 0.5ml of serum is then aliquoted into barcoded 1.8 ml blue capped cryovials. Note: not available for all subjects - Blood sampling required specific informed consent, but this was not provided by all subjects, and in others biomarker collection was not possible for logistic reasons.
LabSampling.LSBiomarkersCollctnTime Original This reflects the biomarker sampling collection time. Protein biomarker sampling was planned in all subjects. 1 x 9ml blood sample was collected in a serum separator tube. After 45 minutes (±15) of coagulation at room temperature, it is centrifuged at 1500g for 10 minutes, 8 x 0.5ml of serum is then aliquoted into barcoded 1.8 ml blue capped cryovials. Note: not available for all subjects - Blood sampling required specific informed consent, but this was not provided by all subjects, and in others biomarker collection was not possible for logistic reasons.
LabSampling.LSBiomarkersFreezerCollctnDate Original This reflects the biomarker freezer date. Protein biomarker sampling was planned in all subjects. 1 x 9ml blood sample was collected in a serum separator tube. After 45 minutes (±15) of coagulation at room temperature, it is centrifuged at 1500g for 10 minutes, 8 x 0.5ml of serum is then aliquoted into barcoded 1.8 ml blue capped cryovials. Note: not available for all subjects - Blood sampling required specific informed consent, but this was not provided by all subjects, and in others biomarker collection was not possible for logistic reasons.
LabSampling.LSBiomarkersFreezerCollctnTime Original This reflects the biomarker freezer time. Protein biomarker sampling was planned in all subjects. 1 x 9ml blood sample was collected in a serum separator tube. After 45 minutes (±15) of coagulation at room temperature, it is centrifuged at 1500g for 10 minutes, 8 x 0.5ml of serum is then aliquoted into barcoded 1.8 ml blue capped cryovials. Note: not available for all subjects - Blood sampling required specific informed consent, but this was not provided by all subjects, and in others biomarker collection was not possible for logistic reasons.
LabSampling.LSBiomarkersNotCollReason Original 1 == No informed consent
2 == Blood draw not successful
3 == Logistic reasons
This specifies the reason why biomarker sampling was not obtained.
LabSampling.LSBloodTransBfSampl Original 0 == No
1 == Yes
99 == Unknown
Reflects if the patient received a blood transfusion before blood sampling
LabSampling.LSCoagulationCollctnDate Original This reflects the Coagulation sampling collection date. Central haemostasis investigations were complementary to routine tests performed by local laboratories at participating sites and were performed only in selected centers. This involved the collection of blood into: 1 x 2.7 ml potassium EDTA tube and 1 x 10 ml and 1 x 5 ml sodium-citrate tubes at the enrollment time points for a limited number of subjects from the Admission and ICU stratum. Post-op samples and Day 2 samples were also obtained in the same two sodium citrate tubes from a limited number of ICU subjects (at this sampling point no potassium EDTA tubes/samples were requested).
LabSampling.LSCoagulationCollctnTime Original This reflects the Coagulation sampling collection time. Central haemostasis investigations were complementary to routine tests performed by local laboratories at participating sites and were performed only in selected centers. This involved the collection of blood into: 1 x 2.7 ml potassium EDTA tube and 1 x 10 ml and 1 x 5 ml sodium-citrate tubes at the enrollment time points for a limited number of subjects from the Admission and ICU stratum. Post-op samples and Day 2 samples were also obtained in the same two sodium citrate tubes from a limited number of ICU subjects (at this sampling point no potassium EDTA tubes/samples were requested).
LabSampling.LSCoagulationFreezerDate Original This reflects the Coagulation sampling freezer date. Central haemostasis investigations were complementary to routine tests performed by local laboratories at participating sites and were performed only in selected centers. This involved the collection of blood into: 1 x 2.7 ml potassium EDTA tube and 1 x 10 ml and 1 x 5 ml sodium-citrate tubes at the enrollment time points for a limited number of subjects from the Admission and ICU stratum. Post-op samples and Day 2 samples were also obtained in the same two sodium citrate tubes from a limited number of ICU subjects (at this sampling point no potassium EDTA tubes/samples were requested).
LabSampling.LSCoagulationFreezerTime Original This reflects the Coagulation sampling freezer time. Central haemostasis investigations were complementary to routine tests performed by local laboratories at participating sites and were performed only in selected centers. This involved the collection of blood into: 1 x 2.7 ml potassium EDTA tube and 1 x 10 ml and 1 x 5 ml sodium-citrate tubes at the enrollment time points for a limited number of subjects from the Admission and ICU stratum. Post-op samples and Day 2 samples were also obtained in the same two sodium citrate tubes from a limited number of ICU subjects (at this sampling point no potassium EDTA tubes/samples were requested).
LabSampling.LSGeneticCollctnDate Original This reflects the Genetic sampling collection date. Two genetic samples should be obtained in all CENTER-TBI participants. It is recognized by the CENTER-TBI coordinators that obtaining genetic samples post transfusion could result in “chimerism” in the genotype and that this could persists for long periods after trauma. However, the coordinators have taken a pragmatic view that samples should be taken at baseline when taking biomarker samples (+/- coagulation samples for those sites in the sub-study). This pragmatic approach has numerous advantages; it limits the complexity of the sampling regimen, reduces the need for repeat venepunctures and minimises the risk of missed samples if the participant is lost to follow-up. Accurate documentation of the participant’s transfusion status is essential for future analysis. In some cases, blood sampling for genetic analysis were obtained later.
LabSampling.LSGeneticCollctnTime Original This reflects the Genetic sampling collection time. Two genetic samples should be obtained in all CENTER-TBI participants. It is recognized by the CENTER-TBI coordinators that obtaining genetic samples post transfusion could result in “chimerism” in the genotype and that this could persists for long periods after trauma. However, the coordinators have taken a pragmatic view that samples should be taken at baseline when taking biomarker samples (+/- coagulation samples for those sites in the sub-study). This pragmatic approach has numerous advantages; it limits the complexity of the sampling regimen, reduces the need for repeat venepunctures and minimises the risk of missed samples if the participant is lost to follow-up. Accurate documentation of the participant’s transfusion status is essential for future analysis. In some cases, blood sampling for genetic analysis were obtained later.
LabSampling.LSGeneticFreezerDate Original This reflects the Genetic sampling freezer date. Two genetic samples should be obtained in all CENTER-TBI participants. It is recognized by the CENTER-TBI coordinators that obtaining genetic samples post transfusion could result in “chimerism” in the genotype and that this could persists for long periods after trauma. However, the coordinators have taken a pragmatic view that samples should be taken at baseline when taking biomarker samples (+/- coagulation samples for those sites in the sub-study). This pragmatic approach has numerous advantages; it limits the complexity of the sampling regimen, reduces the need for repeat venepunctures and minimises the risk of missed samples if the participant is lost to follow-up. Accurate documentation of the participant’s transfusion status is essential for future analysis. In some cases, blood sampling for genetic analysis were obtained later.
LabSampling.LSGeneticFreezerTime Original This reflects the Genetic sampling freezer time. Two genetic samples should be obtained in all CENTER-TBI participants. It is recognized by the CENTER-TBI coordinators that obtaining genetic samples post transfusion could result in “chimerism” in the genotype and that this could persists for long periods after trauma. However, the coordinators have taken a pragmatic view that samples should be taken at baseline when taking biomarker samples (+/- coagulation samples for those sites in the sub-study). This pragmatic approach has numerous advantages; it limits the complexity of the sampling regimen, reduces the need for repeat venepunctures and minimises the risk of missed samples if the participant is lost to follow-up. Accurate documentation of the participant’s transfusion status is essential for future analysis. In some cases, blood sampling for genetic analysis were obtained later.
LabSampling.LSGeneticNotCollReason Original 1 == No informed consent
2 == Blood draw not successful
3 == Logistic reasons
This reflects the reason why Genetic sampling was not obtained.
LabSampling.LSHospitalCollctnDate Original This reflects the blood sampling collection date for routine hospital labs. Sites were requested to document results of all routinely performed lab assessments at baseline, including where possible/applicable point-of-care testing. For patients with multiple labs at different times during the day, a new Lab form was created for each collection
LabSampling.LSHospitalCollctnTime Original This reflects the blood sampling collection time for routine hospital labs. Sites were requested to document results of all routinely performed lab assessments at baseline, including where possible/applicable point-of-care testing. For patients with multiple labs at different times during the day, a new Lab form was created for each collection
LabSampling.LSPointOfCareCollctnDate Original Reflects the date for Point of care testing.
LabSampling.LSPointOfCareCollctnTime Original Reflects the time for Point of care testing
LabSampling.LSTissueCollctnDate Original Reflects the date for Tissue collection.
LabSampling.LSTissueCollctnTime Original Reflects the time for Tissue collection.
MedHx.AnticoagAntiThrombinProtein Original Medical history. Use of anticoagulant or platelet aggregation inhibitor by the patient. This variable describes the use of antithrombin protein therapeutics (Atryn).
MedHx.AnticoagCoumarin Original Medical history. Use of anticoagulant or platelet aggregation inhibitor by the patient. This variable describes the use of Coumarin derivative (Coumadin, Warfarin).
MedHx.AnticoagDirectThrombinInhib Original Medical history. Use of anticoagulant or platelet aggregation inhibitor by the patient. This variable describes the use of direct thrombin inhibitors (eg. dabigatran, argatroban, melagatran).
MedHx.AnticoagFactorXaInhib Original Medical history. Use of anticoagulant or platelet aggregation inhibitor by the patient. This variable describes the use of inhibitor of factor Xa (eg. rivaroxaban).
MedHx.AnticoagHeparin Original Medical history. Use of anticoagulant or platelet aggregation inhibitor by the patient. This variable describes the use of heparin.
MedHx.AnticoagLowMolHeparin Original Medical history. Use of anticoagulant or platelet aggregation inhibitor by the patient. This variable describes the use of low molecular weight heparin
MedHx.AnticoagulantOther Original Medical history. Use of anticoagulant or platelet aggregation inhibitor by the patient. This variable describes the use of another type of anticoagulant or platelet aggregation inhibitor, not specified elsewhere.
MedHx.AnticoagulantOtherTxt Original Medical history. Use of anticoagulant or platelet aggregation inhibitor by the patient. This variable describes the use of another type of anticoagulant or platelet aggregation inhibitor, not specified elsewhere. Text field.
MedHx.AnticoagulantReasonCardiac Original 0 == No
1 == Yes
Medical history. This variable is populated when the reason for using anticoagulants or platelet aggregation inhibitors by the patient is cardiac.
MedHx.AnticoagulantReasonCardiacCABG Original Medical history. This variable is populated when the reason for using anticoagulants or platelet aggregation inhibitors by the patient is cardiac, specifically CABG.
MedHx.AnticoagulantReasonCardiacFibrill Original Medical history. This variable is populated when the reason for using anticoagulants or platelet aggregation inhibitors by the patient is cardiac, specifically atrial fibrillation/flutter.
MedHx.AnticoagulantReasonCardiacStent Original Medical history. This variable is populated when the reason for using anticoagulants or platelet aggregation inhibitors by the patient is cardiac, specifically a cardiac stent.
MedHx.AnticoagulantReasonCardiacValve Original Medical history. This variable is populated when the reason for using anticoagulants or platelet aggregation inhibitors by the patient is cardiac, specifically a valve prosthesis.
MedHx.AnticoagulantReasonCardiovas Original 0 == N0
1 == Yes
Medical history. This variable is populated when the reason for using anticoagulants or platelet aggregation inhibitors by the patient is cardiovascular.
MedHx.AnticoagulantReasonCardiovasCarotidStent Original Medical history. This variable is populated when the reason for using anticoagulants or platelet aggregation inhibitors by the patient is cardiovascular, specifically a carotid or cerebral stent.
MedHx.AnticoagulantReasonCardiovasLimbIsch Original Medical history. This variable is populated when the reason for using anticoagulants or platelet aggregation inhibitors by the patient is cardiovascular, specifically limb ischaemia.
MedHx.AnticoagulantReasonCardiovasOtherStent Original Medical history. This variable is populated when the reason for using anticoagulants or platelet aggregation inhibitors by the patient is cardiovascular, specifically a stent not specified elsewhere.
MedHx.AnticoagulantReasonCardiovasStenosis Original Medical history. This variable is populated when the reason for using anticoagulants or platelet aggregation inhibitors by the patient is cardiovascular, specifically a cardiovascular stenosis
MedHx.AnticoagulantReasonCardiovasTIS Original Medical history. This variable is populated when the reason for using anticoagulants or platelet aggregation inhibitors by the patient is cardiovascular, specifically a transient ischaemic attack/stroke
MedHx.AnticoagulantReasonOther Original Medical history. This variable is populated when the reason for using anticoagulants or platelet aggregation inhibitors by the patient is not specified elsewhere.
MedHx.AnticoagulantReasonOtherTxt Original Medical history. This variable is populated when the reason for using anticoagulants or platelet aggregation inhibitors by the patient is not specified elsewhere (text field).
MedHx.AnticoagulantReasonThrombo Original 0 == No
1 == Yes
Medical history. This variable is populated when the reason for using anticoagulants or platelet aggregation inhibitors by the patient is thromboembolic.
MedHx.AnticoagulantReasonThromboDVTLess6 Original Medical history. This variable is populated when the reason for using anticoagulants or platelet aggregation inhibitors by the patient is thromboembolic, specifically a single episode of DVT (deep venous thrombosis) or PE (pulmonary embolism) <6 months.
MedHx.AnticoagulantReasonThromboDVTMore6 Original Medical history. This variable is populated when the reason for using anticoagulants or platelet aggregation inhibitors by the patient is thromboembolic, specifically a single episode of DVT (deep venous thrombosis) or PE (pulmonary embolism) >6 months.
MedHx.AnticoagulantReasonThromboMultipleEpisode Original Medical history. This variable is populated when the reason for using anticoagulants or platelet aggregation inhibitors by the patient is thromboembolic, specifically two or more episodes of DVT (deep venous thrombosis) or PE (pulmonary embolism).
MedHx.AnticoagXarelto Original Medical history. Use of anticoagulant or platelet aggregation inhibitor by the patient. This variable describes the use of Xarelto
MedHx.BetaBlocker Original 0 == No
1 == Yes
88 == Unknown
A specific question on the use of beta-blockers is included as some reports indicate better outcome with the use of beta blockers (Research interest Rotterdam). If yes, specification is requested and differentiated into: Non-selective blockers/Selective beta-1 blockers/alpha-1 and beta blockers.
MedHx.BetaBlockerAlphaBucundolol Original Medical history. Use of anticoagulant or platelet aggregation inhibitor by the patient. This variable describes the use of a beta blocker, specifically Bucindolol.
MedHx.BetaBlockerAlphaCarvedilol Original Medical history. Use of anticoagulant or platelet aggregation inhibitor by the patient. This variable describes the use of a beta blocker, specifically Carvedilol (Eucardic).
MedHx.BetaBlockerAlphaLabetolol Original Medical history. Use of anticoagulant or platelet aggregation inhibitor by the patient. This variable describes the use of a beta blocker, specifically Labetalol (Trandate).
MedHx.BetaBlockerAlphaOther Original Medical history. Use of anticoagulant or platelet aggregation inhibitor by the patient. This variable describes the use of an alpha 1 and beta-blocker, not specified elsewhere.
MedHx.BetaBlockerAlphaOtherTxt Original Medical history. Use of anticoagulant or platelet aggregation inhibitor by the patient. This variable describes the use of an alpha 1 and beta-blocker, not specified elsewhere (text field).
MedHx.BetaBlockerNonSelectCarteolol Original Medical history. Use of anticoagulant or platelet aggregation inhibitor by the patient. This variable describes the use of beta blockers, specifically Carteolol.
MedHx.BetaBlockerNonSelectNadolol Original Medical history. Use of anticoagulant or platelet aggregation inhibitor by the patient. This variable describes the use of beta blockers, specifically Nadolol
MedHx.BetaBlockerNonSelectOther Original Medical history. Use of anticoagulant or platelet aggregation inhibitor by the patient. This variable describes the use of beta blockers, nonselective, not specified elsewhere.
MedHx.BetaBlockerNonSelectOtherTxt Original Medical history. Use of anticoagulant or platelet aggregation inhibitor by the patient. This variable describes the use of beta blockers, nonselective, not specified elsewhere (textfield).
MedHx.BetaBlockerNonSelectPenbutolol Original Medical history. Use of anticoagulant or platelet aggregation inhibitor by the patient. This variable describes the use of beta blockers, specifically Penbutolo.
MedHx.BetaBlockerNonSelectPindolol Original Medical history. Use of anticoagulant or platelet aggregation inhibitor by the patient. This variable describes the use of beta blockers, specifically Pindolol (Viskeen)
MedHx.BetaBlockerNonSelectPropranolol Original Medical history. This variable describes the use of beta blockers, specifically Propranolol
MedHx.BetaBlockerNonSelectSotalol Original Medical history. This variable describes the use of beta blockers, specifically Sotalol (Sotacor)
MedHx.BetaBlockerSelectAcebutolol Original Medical history. This variable describes the use of beta blockers, specifically Acebutolol (Sectral)
MedHx.BetaBlockerSelectAtenolol Original Medical history. This variable describes the use of beta blockers, specifically Atenolol (Tenormin)
MedHx.BetaBlockerSelectBetaxolol Original Medical history. This variable describes the use of beta blockers, specifically Betaxolol (Kerlon)
MedHx.BetaBlockerSelectBisoprolol Original Medical history. This variable describes the use of beta blockers, specifically Bisoprolol (Emcor)
MedHx.BetaBlockerSelectCeliprolol Original Medical history. This variable describes the use of beta blockers, specifically Celiprolol (Dilanorm)
MedHx.BetaBlockerSelectEsmolol Original Medical history. This variable describes the use of beta blockers, specifically Esmolol (Brevibloc)
MedHx.BetaBlockerSelectMetoprolol Original Medical history. This variable describes the use of beta blockers, specifically Metoprolol (Selokeen).
MedHx.BetaBlockerSelectNebivolol Original Medical history. This variable describes the use of beta blockers, specifically Nebivolol (Nebilet)
MedHx.BetaBlockerSelectOther Original Medical history. This variable describes the use of beta blockers, specifically selective beta1blockers not specified elsewhere.
MedHx.BetaBlockerSelectOtherTxt Original Medical history. This variable describes the use of beta blockers, specifically selective beta1blockers not specified elsewhere (text field).
MedHx.MedHxAnticoagulantsOrPlatelet Original 0 == No
1 == Yes anticoagulants
2 == Yes platelet aggregation inhibitors
3 == Yes, both
88 == Unknown
Summary question to document if the subject was taking anticoagulants or platelet aggregation inhibitors prior to injury. If yes, details are requested concerning which (groups of) agents were used. This information is of high relevance in relation to the shift of epidemiologic patterns in TBI towards higher age (with more co-morbidities and medication).
MedHx.MedHxCardio Original 0 == No
1 == Yes
88 == Unknown
Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting cardiovascular medical history.
MedHx.MedHxCardioArrhythmia Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting cardiovascular medical history, specifically arrhythmia.
MedHx.MedHxCardioCongenitalHD Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting cardiovascular medical history, specifically congenital heart disease.
MedHx.MedHxCardioHTN Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting cardiovascular medical history, specifically hypertension
MedHx.MedHxCardioIschemicHD Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting cardiovascular medical history, specifically Ischemic heart disease
MedHx.MedHxCardioNYHA Original IV == IV
III == III
II == II
I == I
Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting cardiovascular medical history, specifically NYHA, a classification system for severity of cardiac disease - generally used for ischaemia, but used here in broader sense.
MedHx.MedHxCardioOther Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting cardiovascular medical history, not specified elsewhere.
MedHx.MedHxCardioOtherTxt Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting cardiovascular medical history, not specified elsewhere (textfield)
MedHx.MedHxCardioPeripheralVascular Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting cardiovascular medical history, specifically peripheral vascular disease.
MedHx.MedHxCardioThromboembolic Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting cardiovascular medical history, specifically thromboembolic
MedHx.MedHxCardioValvularHD Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting cardiovascular medical history, specifically valvular heart disease
MedHx.MedHxDevelopmental Original 0 == No
1 == Yes
88 == Unknown
Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting developmental diseases.
MedHx.MedHxDevelopmentalADDandADHD Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting developmental diseases, specifically attention deficit/hyperactivity disorder.
MedHx.MedHxDevelopmentalLearningDisability Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting developmental diseases, specifically learning disability
MedHx.MedHxDevelopmentalOther Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting developmental diseases that are not specified elsewhere.
MedHx.MedHxDevelopmentalOtherTxt Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting developmental diseases that are not specified elsewhere (textfield).
MedHx.MedHxEndocrine Original 0 == No
1 == Yes
88 == Unknown
Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting endocrine diseases
MedHx.MedHxEndocrineIDDM Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting endocrine diseases, specifically IDDM (Insulin dependent diabetes mellitus)
MedHx.MedHxEndocrineIDDMControl Original 1 == Well controlled
2 == Difficult controlled
88 == Unknown
Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting for endocrine diseases, specifically IDDM (Insulin dependent diabetes mellitus) - how well it is controlled.
MedHx.MedHxEndocrineNIDDM Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting endocrine diseases, specifically NIDDM (Non-insulin dependent diabetes mellitus)
MedHx.MedHxEndocrineNIDDMControl Original 1 == Well controlled
2 == Difficult controlled
88 == Unknown
Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting for endocrine diseases, specifically NIDDM (Non-insulin dependent diabetes mellitus), how well it is controlled.
MedHx.MedHxEndocrineOther Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting endocrine diseases not mentioned elsewhere.
MedHx.MedHxEndocrineOtherTxt Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting endocrine diseases not specified elsewhere (textfield).
MedHx.MedHxEndocrineThyroid Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting endocrine diseases, specifically thyroid disorder.
MedHx.MedHxENT Original 0 == No
1 == Yes
88 == Unknown
Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting ENT (Eye, Ear, Nose & Throat) disease
MedHx.MedHxENTHearing Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting ENT (Eye, Ear, Nose & Throat) disease, specifically hearing deficits.
MedHx.MedHxENTOther Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting ENT (Eye, Ear, Nose & Throat) diseases not specified elsewhere.
MedHx.MedHxENTOtherTxt Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting ENT (Eye, Ear, Nose & Throat) diseases not specified elsewhere (textfield).
MedHx.MedHxENTSinusitis Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting ENT (Eye, Ear, Nose & Throat) diseases, specifically sinusitis.
MedHx.MedHxENTVisionAbn Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting ENT (Eye, Ear, Nose & Throat) diseases, specifically vision.
MedHx.MedHxGastro Original 0 == No
1 == Yes
88 == Unknown
Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting gastrointestinal disease.
MedHx.MedHxGastroGERD Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting gastrointestinal disease, specifically GERD (Gastroesophageal Reflux Disease).
MedHx.MedHxGastroGIBleed Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting gastrointestinal disease, specifically gastrointestinal bleeding.
MedHx.MedHxGastroIBS Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting gastrointestinal disease, specifically inflammatory bowel disease.
MedHx.MedHxGastroOther Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting gastrointestinal disease not specified elsewhere.
MedHx.MedHxGastroOtherTxt Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting gastrointestinal disease not specified elsewhere (textfield).
MedHx.MedHxHematologic Original 0 == No
1 == Yes
88 == Unknown
Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting hematologic diseases.
MedHx.MedHxHematologicAIDS Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting hematologic diseases, specifically AIDS
MedHx.MedHxHematologicAnemia Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting hematologic diseases, like anemia.
MedHx.MedHxHematologicHIV Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting hematologic diseases, like HIV positive.
MedHx.MedHxHematologicOther Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting hematologic diseases, not specified elsewhere.
MedHx.MedHxHematologicOtherTxt Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting hematologic diseases, not specified elsewhere (textfield).
MedHx.MedHxHematologicSickleCell Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting hematologic diseases, specifically sickle cell disease.
MedHx.MedHxHepatic Original 0 == No
1 == Yes
88 == Unknown
Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting hepatic diseases.
MedHx.MedHxHepaticCirrhosis Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting hepatic diseases, specifically cirrhosis.
MedHx.MedHxHepaticFailure Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting hepatic diseases, specifically hepatic failure
MedHx.MedHxHepaticHepatitis Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting hepatic diseases, specifically hepatitis.
MedHx.MedHxHepaticInsufficiency Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting hepatic diseases, specifically hepatic insufficiency.
MedHx.MedHxHepaticOther Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting hepatic diseases not specified elsewhere
MedHx.MedHxHepaticOtherTxt Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting hepatic diseases not specified elsewhere (textfield)
MedHx.MedHxMusculoskeletal Original 0 == No
1 == Yes
88 == Unknown
Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting musculoskeletal diseases
MedHx.MedHxMusculoskeletalArthritis Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting musculoskeletal diseases, specifically arthritis
MedHx.MedHxMusculoskeletalOther Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting musculoskeletal diseases not specified elsewhere.
MedHx.MedHxMusculoskeletalOtherTxt Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting musculoskeletal diseases not specified elsewhere (textfield)
MedHx.MedHxNeuro Original 0 == No
1 == Yes
88 == Unknown
Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting neurological diseases.
MedHx.MedHxNeuroCerebrovascularAccident Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting neurological diseases, specifically cerebrovascular accidents.
MedHx.MedHxNeuroEpilepsyGeneralized Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting neurological diseases, specifically epilepsy (generalized).
MedHx.MedHxNeuroEpilepsyOther Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting neurological diseases, specifically epilepsy (other).
MedHx.MedHxNeuroEpilepsyPartial Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting neurological diseases, specifically epilepsy (partial).
MedHx.MedHxNeuroFebrileSeizures Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting neurological diseases, specifically febrile seizures (children).
MedHx.MedHxNeuroHeadache Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting neurological diseases, specifically headache (non migraine).
MedHx.MedHxNeuroMigraine Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting neurological diseases, specifically migraines.
MedHx.MedHxNeuroMigraineFamHist Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting neurological diseases, specifically family history of migraine.
MedHx.MedHxNeuroOther Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting neurological diseases not specified elsewhere.
MedHx.MedHxNeuroOtherTxt Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting neurological diseases not specified elsewhere (textfield)
MedHx.MedHxNeuroPain Original 0 == No
1 == Yes
88 == Unknown
Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting neurological diseases not specified elsewhere (textfield)
MedHx.MedHxNeuroTIA Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting neurological diseases, specifically transient ischemic attacks
MedHx.MedHxOncologic Original 0 == No
1 == Yes
88 == Unknown
Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting oncologic diseases.
MedHx.MedHxOncologicBreast Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting oncologic diseases, like breast cancer.
MedHx.MedHxOncologicGI Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting oncologic diseases, specifically gastrointestinal cancer.
MedHx.MedHxOncologicKidney Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting oncologic diseases, specifically kidney cancer.
MedHx.MedHxOncologicLeukemia Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting oncologic diseases, specifically leukemia.
MedHx.MedHxOncologicLung Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting oncologic diseases, specifically lung cancer.
MedHx.MedHxOncologicLymphoma Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting oncologic diseases, specifically lymphoma.
MedHx.MedHxOncologicOther Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting oncologic diseases not specified elsewhere
MedHx.MedHxOncologicOtherTxt Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting oncologic diseases not specified elsewhere (textfield).
MedHx.MedHxOncologicProstate Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting oncologic, specifically prostate cancer.
MedHx.MedHxOther Original 0 == No
1 == Yes
Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting other medical history, not specified elsewhere.
MedHx.MedHxOtherTxt Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting other medical history, not specified elsewhere (textfield)
MedHx.MedHxPreInjASAPSClass Original 1 == A normal healthy patient
2 == A patient with mild systemic disease
3 == A patient with severe systemic disease
4 == A patient with a severe systemic disease that is a constant threat to life
88 == Unknown
Preinjury ASAPS classification. Common classification system used in anaesthesia; denotes overall health
MedHx.MedHxPreTBIConcussions Original 0 == No
1 == Yes
88 == Unknown
Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting previous TBI/ concussions
MedHx.MedHxPreTBIConcussionsTotal Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting total number of previous TBI/ concussions
MedHx.MedHxPreTBIConcussionsTotalHosAdmit Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting total number of hospital admissions for previous TBI/ concussions
MedHx.MedHxPsychiatric Original 0 == No
1 == Yes
88 == Unknown
Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting psychiatric diseases.
MedHx.MedHxPsychiatricAnx Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting psychiatric diseases, specifically anxiety.
MedHx.MedHxPsychiatricDep Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting psychiatric diseases, specifically depression.
MedHx.MedHxPsychiatricOther Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting psychiatric diseases not documented elsewhere.
MedHx.MedHxPsychiatricOtherTxt Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting psychiatric diseases not documented elsewhere (textfield).
MedHx.MedHxPsychiatricSchiz Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting psychiatric diseases, specifically schizophrenia.
MedHx.MedHxPsychiatricSleep Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting psychiatric diseases, specifically sleep disorders.
MedHx.MedHxPsychiatricSubstanceAbuse Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting psychiatric diseases, specifically substance abuse disorders.
MedHx.MedHxPulmonary Original 0 == No
1 == Yes
88 == Unknown
Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting pulmonary diseases
MedHx.MedHxPulmonaryAsthma Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting pulmonary diseases, specifically asthma.
MedHx.MedHxPulmonaryCOPD Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting pulmonary diseases, specifically COPD (Chronic Obstructive Pulmonary Disease)
MedHx.MedHxPulmonaryOther Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting pulmonary diseases not specified elsewhere.
MedHx.MedHxPulmonaryOtherTxt Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting pulmonary diseases not specified elsewhere (textfield).
MedHx.MedHxPulmonaryPneumonia Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting pulmonary diseases, specifically pneumonia.
MedHx.MedHxPulmonaryTB Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting pulmonary diseases, specifically tuberculosis.
MedHx.MedHxRenal Original 0 == No
1 == Yes
88 == Unknown
Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting renal diseases.
MedHx.MedHxRenalFailure Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting renal diseases, specifically renal failure.
MedHx.MedHxRenalInsufficiency Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting renal diseases, specifically renal insufficiency.
MedHx.MedHxRenalOther Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting renal diseases not specified elsewhere.
MedHx.MedHxRenalOtherTxt Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting renal diseases not specified elsewhere (textfield).
MedHx.MedHxRenalUTI Original Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting renal diseases, specifically chronic UTI (urinary tract infection).
MedHx.PlateletAggreOther Original Medical history. Variable documents the use of anticoagulants or platelet aggregation inhibitors. This variable contains the medication of this type not specified elsewhere.
MedHx.PlateletAggreOtherTxt Original Medical history. Variable documents the use of anticoagulants or platelet aggregation inhibitors. This variable contains the medication of this type not specified elsewhere (textfield).
MedHx.PltAggregAdenosineInhib Original Medical history. Use of platelet aggregation inhibitor by the patient. This variable describes the use of an adenosine reuptake inhibitor (eg. Persantin, dipyridamole).
MedHx.PltAggregADPReceptInhib Original Medical history. Use of platelet aggregation inhibitor by the patient. This variable describes the use of ADP receptor inhibitors.
MedHx.PltAggregADPReceptInhibEffient Original Medical history. Use of platelet aggregation inhibitor by the patient. This variable describes the use of Parasugrel (Effient)
MedHx.PltAggregADPReceptInhibOther Original Medical history. Use of platelet aggregation inhibitor by the patient. This variable describes the use of ADP receptor inhibitors, not specified elsewhere.
MedHx.PltAggregADPReceptInhibOtherTxt Original Medical history. Use of platelet aggregation inhibitor by the patient. This variable describes the use of ADP receptor inhibitors, not specified elsewhere (textfield).
MedHx.PltAggregADPReceptInhibPlavix Original Medical history. Use of platelet aggregation inhibitor by the patient. This variable describes the use of Clopidogrel (Plavix).
MedHx.PltAggregADPReceptInhibTiclid Original Medical history. Use of platelet aggregation inhibitor by the patient. This variable describes the use of Ticlopidine (Ticlid).
MedHx.PltAggregAspirin Original Medical history. Use of platelet aggregation inhibitor by the patient. This variable describes the use of Aspirin
MedHx.PltAggregGlycoproteinInhib Original Medical history. Use of platelet aggregation inhibitor by the patient. This variable describes the use of glycoprotein IIB/IIIA inhibitors (eg. Aggrastat).
Medication.Agent Original 1 == Analgesic: paracetamol
2 == Analgesic: NSAIDs
3 == Analgesic: tramadol
4 == Analgesic: opioids (morphine, ect)
5 == Sedatives/treatment of agitation: barbiturates (penthothal, ect)
6 == Sedatives/treatment of agitation: clondine
7 == Sedatives/treatment of agitation: dexmedetomidine
8 == Sedatives/treatment of agitation: diazepam
9 == Sedatives/treatment of agitation: fentanyl
10 == Sedatives/treatment of agitation: haloperidol (haldol)
11 == Sedatives/treatment of agitation: lorazepam (tenesta, ect)
12 == Sedatives/treatment of agitation: midazolam
13 == Sedatives/treatment of agitation: morphine
14 == Sedatives/treatment of agitation: propofol
15 == Sedatives/treatment of agitation: other
16 == Neuromuscular blockade: pancuronium (pavulon)
17 == Neuromuscular blockade: atracurium (tracium)
18 == Neuromuscular blockade: cisatracurium (nimbex)
19 == Neuromuscular blockad: gallamine (flaxedil)
20 == Neuromuscular blockade: rocuronium (zemuron)
21 == Neuromuscular blockade: vecuronium (norcuron)
22 == Neuromuscular blockade: other
23 == Anti- epileptic: carbamazepine (tegretol)
24 == Anti- epileptic: lamotrigine (lamectal)
25 == Anti- epileptic: levetirazetam (keppra)
26 == Anti- epileptic: phenytoine (diphantoine)
27 == Anti- epileptic: valproate (depakine)
28 == Anti- epileptic: other
29 == Antibiotics: aminoglycoside (amikacine, gentamicine etc)
30 == Antibiotics: carbapemens (meronem etc)
31 == Antibiotics: cephalosporin 1st gen (cefalexin etc)
32 == Antibiotics: cephalosporin 2nd gen (cefuroxim etc)
33 == Antibiotics: cephalosporin 3rd gen (cefotaxine etc)
34 == Antibiotics: cephalosporin 4th gen (cefepime, maxipime etc)
35 == Antibiotics: cephalosporin 5th gen (ceftasoline etc)
36 == Antibiotics: glycopeptides (vancomycine)
37 == Antibiotics: lincosamides (clindamycine etc)
38 == Antibiotics: macrolidis (erythromycine etc)
39 == Antibiotics: nitrofurones (furoxone, furadantine etc)
40 == Antibiotics: penicillines (ampicilline, cloxacilline)
41 == Antibiotics: amoxycilline/clavulanic acid (augmentin, tyclav etc)
42 == Antibiotics: quinolones (ciprofloxacine etc)
43 == Antibiotics: sulfonamides (co-trimoxazole, doxycycline)
44 == Antibiotics: other
45 == Anti- hypertensive: ACE blockers (captopril, perindopril etc)
46 == Anti- hypertensive: angiotensininhibitors (cardesartan etc)
47 == Anti- hypertensive: bètablockers (propanolol)
48 == Anti- hypertensive: clonidine
49 == Anti- hypertensive: diuretics
50 == Calcium channel blockers: nimodipine
51 == Calcium channel blockers: nicardipine
52 == Calcium channel blockers: verapamil
53 == Steroids: methylprednisolone
54 == Steroids: bétametasone
55 == Steroids: dexametasone
56 == Steroids: hydrocortisone/cortisone
57 == Antacids: Aluminium hydroxide
58 == Antacids: other
59 == H2 receptor antagonist: Cimetidine
60 == H2 receptor antagonist: Ranitidine (Zantac)
61 == Proton pump inhibitors: Omeprazol (Losec)
62 == Proton pump inhibitors: Esomeprazol (Nexium)
63 == Proton pump inhibitors: Pantoprazole (Pantozol)
64 == Prokinetics: Domperidon (Motilium)
65 == Prokinetics: Erythromycin
66 == Prokinetics: Metoclopramide (Primperan)
67 == Analgesic: other
68 == Anti- hypertensive: other
69 == Calcium channel blockers: other
70 == Steroids: other
71 == H2 receptor antagonist: other
72 == Proton pump inhibitors: other
73 == Prokinetics:other
99 == Other, specify in Agent Other: Other
Details on medication captured information on Class, Agent, Reason, Highest daily dose, Route, start and stop date and whether or not medication has been ongoing after discharge. This variable describes the Agent. Agents commonly used for treatment of raised ICP are listed in the TIL section, but not included in the medication lists here.
Medication.AgentOther Original Details on medication captured information on Class, Agent, Reason, Highest daily dose, Route, start and stop date and whether or not medication has been ongoing after discharge. This variable describes if the Agent was "other" than the predefined list.
Medication.Class Original 1 == Analgesic
2 == Sedatives/treatment of agitation
3 == Neuromuscular blockade
4 == Anti- epileptic
5 == Antibiotics
6 == Anti- hypertensive
7 == Calcium channel blockers
8 == Steroids
9 == Antacids
10 == H2 receptor antagonist
11 == Proton pump inhibitors
12 == Prokinetics
99 == Other, specify in Agent Other
Details on medication captured information on Class, Agent, Reason, Highest daily dose, Route, start and stop date and whether or not medication has been ongoing after discharge. This variable describes the Classes. Classes: analgesic, sedatives, neuromuscular blocking agents, anti-epileptic drugs, antibiotiucs, anti-hypertensive, calcium channel blockers, steroids, antacids, H2 receptor antagonists, proton pump inhibitors and prokinetics. Agents commonly used for treatment of raised ICP are listed in the TIL section, but not included in the medication lists here.
Medication.HighestDailyDose Original Details on medication captured information on Class, Agent, Reason, Highest daily dose, Route, start and stop date and whether or not medication has been ongoing after discharge. This variable describes the Highest Daily Dose. These details should be entered for each agent.
Medication.Ongoing Original Details on medication captured information on Class, Agent, Reason, Highest daily dose, Route, start and stop date and whether or not medication has been ongoing after discharge. This variable describes if medication was still ongoing on discharge. These details should be entered for each agent.
Medication.Reason Original 1 == Sedatives/treatment of agitation: mechanical ventilation
2 == Sedatives/treatment of agitation: metabolic suppression
3 == Anti- epileptic: prophylaxis
4 == Anti- epileptic: treatment of overt seizure
6 == Anti- epileptic: treatment of (silent) seizure activity
7 == Antibiotics: fever, no clear focus
8 == Antibiotics: pneumonia
9 == Antibiotics: urinary tract infection
10 == Antibiotics: catheter related bloodstream infection
11 == Antibiotics: intracranial abces/empyeme
12 == Antibiotics: periprocedural prophylaxis
13 == Antibiotics: meningitis
14 == Anti- hypertensive: to lower blood pressure
15 == Anti- hypertensive: treatment agitation
16 == Calcium channel blockers: prevention of vasospasm
17 == Calcium channel blockers: treatment of vasospasm
18 == Calcium channel blockers: anti- hypertensive
19 == Calcium channel blockers: cardiac indication
20 == Steroids: traumatic brain injury
21 == Steroids: ARDS
22 == Steroids: hypopituitarism
23 == Steroids: sepsis
24 == Antacids: gastric protection
25 == Antacids: reflux
26 == H2 receptor antagonist: gastric protection
27 == H2 receptor antagonist: treatment of ulcer
28 == Proton pump inhibitors: gastric protection
29 == Proton pump inhibitors: treatment of ulcer
30 == Prokinetics: gastric retention
31 == Prokinetics: vomiting
32 == Prokinetics: constipation
33 == Prokinetics: routine care
35 == Analgesic: other
36 == Neuromuscular blockade: other
37 == Sedatives/treatment of agitation: Other
38 == Anti- epileptic: Other
39 == Antibiotics: Other
40 == Anti- hypertensive: Other
41 == Calcium channel blockers: Other
42 == Steroids: Other
43 == Antacids: Other
44 == H2 receptor antagonist: Other
45 == Proton pump inhibitors: Other
46 == Prokinetics: Other
99 == Other, specify in Agent Other: Other
Details on medication captured information on Class, Agent, Reason, Highest daily dose, Route, start and stop date and whether or not medication has been ongoing after discharge. This variable describes the Reason for medication. These details should be entered for each agent.
Medication.ReasonOther Original Details on medication captured information on Class, Agent, Reason, Highest daily dose, Route, start and stop date and whether or not medication has been ongoing after discharge. This variable describes the Reason for medication if this was "other than the predefined ones. These details should be entered for each agent.
Medication.Route Original ED == Epidural
IvCont == Continuous IV
IvInt == Intermittent IV
Ih == Inhaled
Re == Rectal
Im == Intramuscular
PO == Oral
Pv == Vaginal
To == Topical
Sc == Subcutaneous
Details on medication captured information on Class, Agent, Reason, Highest daily dose, Route, start and stop date and whether or not medication has been ongoing after discharge. This variable describes the Route. These details should be entered for each agent.
Medication.StartDate Original Details on medication captured information on Class, Agent, Reason, Highest daily dose, Route, start and stop date and whether or not medication has been ongoing after discharge. This variable describes the Start date for medication. These details should be entered for each agent.
Medication.StopDate Original Details on medication captured information on Class, Agent, Reason, Highest daily dose, Route, start and stop date and whether or not medication has been ongoing after discharge. This variable describes the Stop date for medication. These details should be entered for each agent.
Meds.DVTMechOngoing Original These variables aim to document specific information on the use of DVT prophylaxis. Little evidence exists on the use and timing of DVT prophylaxis after TBI, and considerable practice variation exists. This variable describes if Mechanical DVT was still ongoing after discharge.
Meds.DVTPharmOngoing Original These variables aim to document specific information on the use of DVT prophylaxis. Little evidence exists on the use and timing of DVT prophylaxis after TBI, and considerable practice variation exists. This variable describes if Pharmacologic DVT was still ongoing after discharge.
Meds.DVTPharmType Original 1 == Heparin
2 == Low molecular weight Heparin
3 == Dalteparin (Fragmin)
4 == Enoxaparin
5 == Nadroparin (Fraxiparine, Fraxodil)
6 == Parnaparin
7 == Reviparin
8 == Tinzaparin
These variables aim to document specific information on the use of DVT prophylaxis. Little evidence exists on the use and timing of DVT prophylaxis after TBI, and considerable practice variation exists. This variable describes the Type of prophylaxis in case of Pharmacologic DVT.
Meds.DVTProphylaxisMech Original 0 == No
1 == Yes
These variables aim to document specific information on the use of DVT prophylaxis. Little evidence exists on the use and timing of DVT prophylaxis after TBI, and considerable practice variation exists. This variable describes presence or absence of Mechanical DVT .
Meds.DVTProphylaxisMechStartDate Original These variables aim to document specific information on the use of DVT prophylaxis. Little evidence exists on the use and timing of DVT prophylaxis after TBI, and considerable practice variation exists. This variable describes Start date of Mechanical DVT.
Meds.DVTProphylaxisMechStopDate Original These variables aim to document specific information on the use of DVT prophylaxis. Little evidence exists on the use and timing of DVT prophylaxis after TBI, and considerable practice variation exists. This variable describes Stop Date of Mechanical DVT.
Meds.DVTProphylaxisMechType Original These variables aim to document specific information on the use of DVT prophylaxis. Little evidence exists on the use and timing of DVT prophylaxis after TBI, and considerable practice variation exists. This variable describes the Type of prophylaxis in case of Mechanical DVT.
Meds.DVTProphylaxisPharm Original 0 == No
1 == Yes
These variables aim to document specific information on the use of DVT prophylaxis. Little evidence exists on the use and timing of DVT prophylaxis after TBI, and considerable practice variation exists. This variable describes presence or absence of Pharmacologic DVT.
Meds.DVTProphylaxisStartDate Original These variables aim to document specific information on the use of DVT prophylaxis. Little evidence exists on the use and timing of DVT prophylaxis after TBI, and considerable practice variation exists. This variable describes Start date of Pharmacologic DVT.
Meds.DVTProphylaxisStopDate Original These variables aim to document specific information on the use of DVT prophylaxis. Little evidence exists on the use and timing of DVT prophylaxis after TBI, and considerable practice variation exists. This variable describes Stop date of Pharmacologic DVT.
Meds.EnteralNutrition Original 0 == No
1 == Yes
These variables aim to document specific information on nutritional support, provided by parenteral and/or enteral routes. This variable describes the absence or presence of Enteral Nutrition.
Meds.EnteralNutritionRoute Original 1 == Nasogastric tube
2 == Transpyloric tube
3 == Gastrostomy
These variables aim to document specific information on nutritional support, provided by parenteral and/or enteral routes. This variable describes the route of administration for Enteral Nutrition.
Meds.EnteralNutritionStartDate Original These variables aim to document specific information on nutritional support, provided by parenteral and/or enteral routes. This variable describes the Start Date of Enteral Nutrition.
Meds.EnteralNutritionStopDate Original These variables aim to document specific information on nutritional support, provided by parenteral and/or enteral routes. This variable describes the Stop Date of Enteral Nutrition.
Meds.Intubation Original 0 == No
1 == Yes
This variable describes the absence or presence of Intubation as Ventilation Management (only for ICU patients).
Meds.IntubationStartDate Original This variable describes the Start Date in case of Intubation as Ventilation Management (only for ICU patients).
Meds.IntubationStartTime Original This variable describes the Start Time in case of Intubation as Ventilation Management (only for ICU patients).
Meds.IntubationStop Original 0 == No
1 == Yes
This variable describes the absence or presence of Extubation in case of Ventilation Management (only for ICU patients).
Meds.IntubationStopDate Original This variable describes the Stop Date of Extubation in case of Ventilation Management (only for ICU patients).
Meds.IntubationStopReason Original 1 == Respiratory stable
2 == Accidental
3 == Withdrawal of care
This variable describes the Stop Reason of Extubation in case of Ventilation Management (only for ICU patients).
Meds.IntubationStopTime Original This variable describes the Stop Time of Extubation in case of Ventilation Management (only for ICU patients).
Meds.MechVentilation Original 0 == No
1 == Yes
This variable describes the absence or presence of Mechanical Ventilation (any respiratory mode except for CPAP).
Meds.MechVentilationStartDate Original This variable describes the Start Date of Mechanical Ventilation (any respiratory mode except for CPAP).
Meds.MechVentilationStartTime Original This variable describes the Start Time of Mechanical Ventilation (any respiratory mode except for CPAP).
Meds.MechVentilationStopDate Original This variable describes the Stop Date of Mechanical Ventilation (any respiratory mode except for CPAP).
Meds.MechVentilationStopTime Original This variable describes the Stop Time of Mechanical Ventilation (any respiratory mode except for CPAP).
Meds.Nasogastric Original 0 == No
1 == Yes
Reflects absence or presence of a Nasogastric feeding tube.
Meds.NasogastricOngoing Original Reflects if a Nasogastric feeding tube remained ongoing.
Meds.NasogastricStartDate Original Reflects Start Date of a Nasogastric feeding tube.
Meds.NasogastricStopDate Original Reflects Stop Date of a Nasogastric feeding tube.
Meds.OxygenAdm Original 0 == No
1 == Yes
88 == Unknown
Reflects presence or absence of Oxygen Administration.
Meds.OxygenAdmOngoing Original Reflects if Oxygen Administration remained ongoing.
Meds.OxygenAdmStartDate Original Reflects Start Date of Oxygen Administration.
Meds.OxygenAdmStopDate Original Reflects Stop Date of Oxygen Administration.
Meds.ParenteralNutrition Original 0 == No
1 == Yes
These variables aim to document specific information on nutritional support, provided by parenteral and/or enteral routes. This variable describes the absence or presence of Parenteral Nutrition.
Meds.ParenteralNutritionStartDate Original These variables aim to document specific information on nutritional support, provided by parenteral and/or enteral routes. This variable describes the Start Date of Parenteral Nutrition.
Meds.ParenteralNutritionStopDate Original These variables aim to document specific information on nutritional support, provided by parenteral and/or enteral routes. This variable describes the Stop Date of Parenteral Nutrition.
Meds.PEGTube Original 0 == No
1 == Yes
This variable describes the absence or presence of a PEG tube (gastrostomy).
Meds.PEGTubeOngoing Original This variable describes if presence of a PEG tube (gastrostomy) remained ongoing.
Meds.PEGTubeStartDate Original This variable describes the Start Date of a PEG tube (gastrostomy)
Meds.PEGTubeStopDate Original This variable describes the Stop Date of a PEG tube (gastrostomy)
Meds.ReIntubation Original 0 == No
1 == Yes
Reflects if there has been a need for re-intubation.
Meds.ReIntubationStartDate Original Reflects Start Date in case of need for re-intubation.
Meds.ReIntubationStartTime Original Reflects Start Time in case of need for re-intubation.
Meds.ReMechVentilation Original 0 == No
1 == Yes
Reflects the need for re-instituting mechanical ventilation.
Meds.ReMechVentilationReason Original 1 == Respiratory failure
2 == Neurologic deterioration
3 == Spontaneous hyperventilation
4 == Sepsis
99 == Other
Reflects the reason for the need of re-instituting mechanical ventilation.
Meds.ReMechVentilationReasonOther Original Reflects the "other" reason for the need of re-instituting mechanical ventilation.
Meds.ReMechVentilationStartDate Original Reflects the Start Date for the need of re-instituting mechanical ventilation.
Meds.ReMechVentilationStartTime Original Reflects the Start Time for the need of re-instituting mechanical ventilation.
Meds.TakenMeds Original 0 == No
1 == Yes
Reflects if the patient has taken any medications. Documentation of concomitant medication largely follows a pre-defined structure: A total of 12 classes of drugs are pre-defined, each with a drop-down menu of 1-15 most commonly used agents. The reason for prescribing, the highest daily dose&units as well as route of administration is documented. For agents not listed in the drop-down menu's, the option "other" permits free text entries.
Meds.Tracheostomy Original 0 == No
1 == Yes
Describes absence or presence of a Tracheostomy.
Meds.TracheostomyOngoing Original Describes if a Tracheostomy remained ongoing.
Meds.TracheostomyStartDate Original Describes Start Date of a Tracheostomy.
Meds.TracheostomyStopDate Original Describes Stop Date of a Tracheostomy.
Meds.UrineCath Original 0 == No
1 == Yes
Describes absence or presence of an Urinary catheter.
Meds.UrineCathOngoing Original Describes if an Urinary catheter remained ongoing.
Meds.UrineCathStartDate Original Describes Start Date of an Urinary catheter.
Meds.UrineCathStopDate Original Describes Stop Date of an Urinary catheter.
Meds.VentilationMgmtNA Original Describes if Ventilation Management was not applicable because patient was not in ICU.
Outcomes.10mWALKBestTestTime Original Describes the best trial time for the 10m Walk outcome test.
Outcomes.10mWALKCompletionCode Original 1.0 == 1.0 Test completed in full
1.1 == 1.1 Non-standard adm - written
1.2 == 1.2 Non-standard adm - other
1.3 == 1.3 Test completed over the phone
2.1 == 2.1 Not completed - Cognitive/neuro
2.2 == 2.2 Not completed - Non-neuro/phys
2.3 == 2.3 Not completed - Poor effort
2.4 == 2.4 Not completed - Language
2.5 == 2.5 Not completed - Illness
2.6 == 2.6 Not completed - Logistical
3.1 == 3.1 Not attempted - Cognitive/neuro
3.2 == 3.2 Not attempted - Non-neuro/phys
3.3 == 3.3 Not attempted - Poor effort
3.4 == 3.4 Not attempted - Language
3.5 == 3.5 Not attempted - Illness
3.6 == 3.6 Not attempted - Logistical
4.0 == 4.0 Not attempted - Examiner error
5.0 == 5.0 Not attempted - Other
Describes if the 10m Walk outcome test was completed or not and the reason if not.
Outcomes.10mWALKDate Original Describes the Date of the 10m Walk outcome test.
Outcomes.10mWALKTest1 Original Describes the Test 1 time for the 10m Walk outcome test.
Outcomes.10mWALKTest2 Original Describes the Test 2 time for the 10m Walk outcome test.
Outcomes.10mWALKTest3 Original Describes the Test 3 time for the 10m Walk outcome test.
Outcomes.10mWALKTestAttemptdNotCompOptions Original 2.1 == Not completed - Cognitive/neurological deficits
2.2 == Not completed - Non-neurological/physical reason
2.3 == Not completed - Lack of effort/uncooperative
2.4 == Not completed - Language
2.5 == Not completed - Illness/fatigue
2.6 == Not completed - Logistical reasons, other reasons
2.7 == Not completed - Examiner error
This variable describes why the 10m Walk test was attempted, but not completed.
Outcomes.10mWALKTestAttemptdNotCompOptionsOTHER Original This variable describes the "other" reason why the 10m Walk test was attempted, but not completed.
Outcomes.10mWALKTestCompletedOptions Original 3.0 == Test completed in full - results valid
3.1 == Test completed - Non-standard, results valid
3.2 == Non-standard administration - Other
Describes the test completeness for the 10m Walk outcome test.
Outcomes.10mWALKTestComplNonStandAdminOTHER Original This variable specifies the "other" reason for the 10m Walk outcome test in case of "Non-standard administration - Other".
Outcomes.10mWALKTestNotDoneOptions Original 1.1 == Not attempted - Cognitive/neurological deficits
1.2 == Not attempted - Non-neurological/physical reasons
1.3 == Not attempted - Lack of effort/uncooperative
1.4 == Not attempted - Language
1.5 == Not attempted - Illness/fatigue
1.6 == Not attempted - Logistical reasons, other reasons
1.7 == Not attempted - Examiner error
1.8 == Not attempted - Patient not available
This variable describes the reason why the 10m Walk test was not done.
Outcomes.10mWALKTestNotDoneOptionsOTHER Original This variable specifies the "other" reason for why the 10m Walk test was not done.
Outcomes.10mWALKTUGNeuroPsychCompCode Original 1.0 == 1.0 Test not done
2.0 == 2.0 Test attempted but not completed
3.0 == 3.0 Test completed
This variable describes the completion status of the 10m Walk outcome assessment.
Outcomes.CANTABAST Meta 1.0 == 1.0 Test completed in full
1.1 == 1.1 Non-standard adm - written
1.2 == 1.2 Non-standard adm - other
1.3 == 1.3 Test completed over the phone
2.1 == 2.1 Not completed - Cognitive/neuro
2.2 == 2.2 Not completed - Non-neuro/phys
2.3 == 2.3 Not completed - Poor effort
2.4 == 2.4 Not completed - Language
2.5 == 2.5 Not completed - Illness
2.6 == 2.6 Not completed - Logistical
3.1 == 3.1 Not attempted - Cognitive/neuro
3.2 == 3.2 Not attempted - Non-neuro/phys
3.3 == 3.3 Not attempted - Poor effort
3.4 == 3.4 Not attempted - Language
3.5 == 3.5 Not attempted - Illness
3.6 == 3.6 Not attempted - Logistical
4.0 == 4.0 Not attempted - Examiner error
5.0 == 5.0 Not attempted - Other
Reflects if the CANTAB AST (Attention Switching Task) was completed or not and the reason if not. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTCompCode Original 1.0 == Test not done
2.0 == Test attempted, but not completed
3.0 == Test completed
Reflects if the CANTAB AST (Attention Switching Task) was done or not. Completion codes of CANTAB testings were not automatically filled in in the outcome assessment form. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTCongruencyCostMeanBlock3Correct Derived Attention Switching Task (AST): The difference between the median latency of response (from stimulus appearance to button press) on the trials that were congruent versus the trials that were incongruent. Mean for correct trials in Block 3. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTCongruencyCostMeanBlock5Correct Derived Attention Switching Task (AST): The difference between the median latency of response (from stimulus appearance to button press) on the trials that were congruent versus the trials that were incongruent. Mean for correct trials in Block 5. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTCongruencyCostMeanBlock7Correct Derived Attention Switching Task (AST): The difference between the median latency of response (from stimulus appearance to button press) on the trials that were congruent versus the trials that were incongruent. Mean for correct trials in Block 7. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTCongruencyCostMeanCorrect Derived Attention Switching Task (AST): The difference between the median latency of response (from stimulus appearance to button press) on the trials that were congruent versus the trials that were incongruent. Mean for all correct trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTCongruencyCostMedianBlock3Correct Derived Attention Switching Task (AST): The difference between the median latency of response (from stimulus appearance to button press) on the trials that were congruent versus the trials that were incongruent. Median for correct trials in Block 3. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTCongruencyCostMedianBlock5Correct Derived Attention Switching Task (AST): The difference between the median latency of response (from stimulus appearance to button press) on the trials that were congruent versus the trials that were incongruent. Median for correct trials in Block 5. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTCongruencyCostMedianBlock7Correct Derived Attention Switching Task (AST): The difference between the median latency of response (from stimulus appearance to button press) on the trials that were congruent versus the trials that were incongruent. Median for correct trials in Block 7. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTCongruencyCostMedianCorrect Derived Attention Switching Task (AST): The difference between the median latency of response (from stimulus appearance to button press) on the trials that were congruent versus the trials that were incongruent. Median for all correct trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTCongruencyCostSDBlock3Correct Derived Attention Switching Task (AST): The difference between the median latency of response (from stimulus appearance to button press) on the trials that were congruent versus the trials that were incongruent. Standard deviation for correct trials in Block 3. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTCongruencyCostSDBlock5Correct Derived Attention Switching Task (AST): The difference between the median latency of response (from stimulus appearance to button press) on the trials that were congruent versus the trials that were incongruent. Standard deviation for correct trials in Block 5. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTCongruencyCostSDBlock7Correct Derived Attention Switching Task (AST): The difference between the median latency of response (from stimulus appearance to button press) on the trials that were congruent versus the trials that were incongruent. Standard deviation for correct trials in Block 7. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTCongruencyCostSDCorrect Derived Attention Switching Task (AST): The difference between the median latency of response (from stimulus appearance to button press) on the trials that were congruent versus the trials that were incongruent. Standard deviation for all correct trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTMeanCorrectLatency Derived Attention Switching Task (AST): Mean response latency on all correct trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTMeanCorrectLatencyCongruent Derived Attention Switching Task (AST): Mean response latency on correct congruent trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTMeanCorrectLatencyDirection Derived Attention Switching Task (AST): Mean response latency on correct direction task trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTMeanCorrectLatencyIncongruent Derived Attention Switching Task (AST): Mean response latency on correct incongruent task trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTMeanCorrectLatencyNonSwitched Derived Attention Switching Task (AST): Mean response latency on correct task non-switched trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTMeanCorrectLatencySide Derived Attention Switching Task (AST): Mean response latency on correct side task trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTMeanCorrectLatencySwitched Derived Attention Switching Task (AST): Mean response latency on correct task switched trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTMedianCorrectLatency Derived Attention Switching Task (AST): Median response latency on all correct trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTMedianCorrectLatencyCongruent Derived Attention Switching Task (AST): Median response latency on correct congruent trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTMedianCorrectLatencyDirection Derived Attention Switching Task (AST): Median response latency on correct direction task trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTMedianCorrectLatencyIncongruent Derived Attention Switching Task (AST): Median response latency on correct incongruent task trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTMedianCorrectLatencyNonSwitched Derived Attention Switching Task (AST): Median response latency on correct task non-switched trials. Time in msec. For more detailed information on CANTAB