Variable Lookup values Description
AIS.InjAIS 0 == 0
1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
In the original AIS classification of injury severity, the grading is from 1 (minor) to 6 (unsurvivable). We added a score of 0 to designate absence of injuries. This is the AIS score for body regions as specified by AIS.InjBodyRegion.
AIS.InjBodyRegion 1 == Externa
2 == Head and Neck-Other
3 == Brain Injury
4 == Cervical Spine
5 == Face
6 == Thorax/Chest
7 == Thoracic Spine
8 == Abdomen/Pelvic Contents
9 == Lumbar Spine
10 == Upper Extremities
11 == Lower Extremities
12 == Pelvic Girdle
Injuries and their severity are recorded according to a (modification of) the AIS. The AIS recognizes 6 main body regions. We included a further subdivision for some body regions, resulting in a total of 12 regions. For example, spine is not considered separately in the original AIS classification, but included under neck/chest and abdomen regions. For TBI, however, we considered it important to record spine separately.
AIS.InjDescription 1 == Brain Injury: Concussion
2 == Brain Injury: Contusions
3 == Brain Injury: EDH
4 == Brain Injury: Diffuse Injury
5 == Brain Injury: ASDH
6 == Brain Injury: Other
7 == Head and Neck-Other: Specify in comments box
8 == Cervical Spine: Fracture
9 == Cervical Spine: Dislocation
10 == Cervical Spine: Other
11 == Face: Maxillo-facial fracture le Fort I
12 == Face: Maxillo-facial fracture le Fort II
13 == Face: Maxillo-facial fracture le Fort III
14 == Face: Orbital fracture
15 == Face: Zygomatic arch fracture
16 == Face: Other
17 == Thorax/Chest: Rib fracture
18 == Thorax/Chest: Lung contusion
19 == Thorax/Chest: Cardiac contusion
20 == Thorax/Chest: Aorta dissection
21 == Thorax/Chest: Pneumo-thorax
22 == Thorax/Chest: Hemato-thorax
23 == Thorax/Chest: Other
24 == Thoracic Spine: Fracture
25 == Thoracic Spine: Dislocation
26 == Abdomen/Pelvic Contents: Spleen rupture
27 == Abdomen/Pelvic Contents: Liver rupture
28 == Abdomen/Pelvic Contents: Perforating abdominal injury
29 == Abdomen/Pelvic Contents: Kidney contusion
30 == Abdomen/Pelvic Contents: Retroperitoneal hematoma
31 == Abdomen/Pelvic Contents: Other
32 == Lumbar Spine: Fracture
33 == Lumbar Spine: Dislocation
34 == Lumbar Spine: Sacral fracture
35 == Lumbar Spine: Other
36 == Upper Extremities: Humerus fracture
37 == Upper Extremities: Radial and/or ulnar fracture
38 == Upper Extremities: Dislocation
39 == Upper Extremities: Hand
40 == Upper Extremities: Finger
41 == Lower Extremities: Femoral fracture
42 == Lower Extremities: Tibia plateau fracture
43 == Lower Extremities: Tibia fracture
44 == Lower Extremities: Ankle fracture
45 == Lower Extremities: Calcaneus fracture
46 == Lower Extremities: Metatarsal/tarsal fracture (toe fracture)
47 == Lower Extremities: Fibula fracture
48 == Pelvic Girdle: Pelvic fracture
49 == Pelvic Girdle: Hip fracture
50 == Pelvic Girdle: Hip dislocation
51 == Externa: Other
52 == Thoracic Spine: Other
53 == Upper Extremities: Other
54 == Lower Extremities: Other
55 == Pelvic Girdle: Other
List of body regions with 55 subcategories describing the injury.
AIS.InjDesOther Free text specifying the injury when AIS.InjDescription is "other"
Brainmonitoring.DataAvailable Meta data from the High Resolution ICU data collected in a subcategory of patients in specific HR-ICU sites.
Brainmonitoring.DataCollectionSoftware Meta data from the High Resolution ICU data collected in a subcategory of patients in specific HR-ICU sites.
Brainmonitoring.DataEndTime Meta data from the High Resolution ICU data collected in a subcategory of patients in specific HR-ICU sites.
Brainmonitoring.DataProcessingSoftware Meta data from the High Resolution ICU data collected in a subcategory of patients in specific HR-ICU sites.
Brainmonitoring.DataStartTime Meta data from the High Resolution ICU data collected in a subcategory of patients in specific HR-ICU sites.
Brainmonitoring.DateTimeFormat
Brainmonitoring.Duration Meta data from the High Resolution ICU data collected in a subcategory of patients in specific HR-ICU sites.
Brainmonitoring.FormatVersion Meta data from the High Resolution ICU data collected in a subcategory of patients in specific HR-ICU sites.
Brainmonitoring.HDF5URL URL to download high resolution ICU file
Brainmonitoring.InvalidValue Meta data from the High Resolution ICU data collected in a subcategory of patients in specific HR-ICU sites.
CTMRI.CTAcuteSubdurHema 0 == No
1 == Small
2 == Large (mass)
88 == Unknown
Assessment by clinician/investigator whether or not in his/her interpretation an acute subdural hematoma is present. Also, the size (not quantified) is requested to be estimated.
CTMRI.CTAngulation 1 == No angulation (volume scan)
2 == Orbital-meatal line
99 == Other
This variable describes if a CT scan is performed with or without angulation. There are three options: no angulation (volume scan), orbital-meatal line and other. There is a risk of different interpretation, since there was no definition.
CTMRI.CTBasalCisternsAbsentCompressed 0 == No
1 == Yes
Assessment by clinician/investigator whether or not in his/her interpretation the basal cisterns are compressed.
CTMRI.CTContusion 0 == No
1 == Small
2 == Large (mass)
88 == Unknown
Assessment by clinician/investigator whether or not in his/her interpretation an intracerebral hematoma/contusion is present. Also, the size (not quantified) is requested to be estimated.
CTMRI.CTDeprSkullFract 0 == No
1 == Closed
2 == Open (compound)
Assessment by clinician/investigator whether or not in his/her interpretation a depressed skull fracture is present. In addition, when present, clinician/investigator has to document whether the fracture is associated with an open wound or not (compound vs closed)
CTMRI.CTDone This variable is populated when a CT has been made. Intent to perform a CT was an inclusion criterium for the study. All Images performed have been uploaded to the Imaging repository at Icometrix. Central review of initial and follow-up scans has been done by icometrix. Data of Central review are recorded separately. The variables below capture results of basic scoring by Investigators - these scores inform clinical decision making!
CTMRI.CTERReason 1 == GCS <= 14
2 == GCS = 15 + risk factors
3 == Head wound
4 == Exclusion of abnormalities prior to discharge
5 == Suspicion of maxillofacial injury
88 == Unknown
99 == Other
WHY question: reason for performing CT; only applicable to initial scan (presentation).
CTMRI.CTERReasonOther Specification, only applicable if "CTMRI.CTERReason" was "other"
CTMRI.CTExtraduralHema 0 == No
1 == Small
2 == Large (mass)
88 == Unknown
Assessment by clinician/investigator whether or not in his/her interpretation an acute extradural/epidural hematoma is present. Also, the size (not quantified) is requested to be estimated.
CTMRI.CTICLesionDAI 0 == No
1 == Yes
88 == Unknown
Assessment by clinician/investigator whether or not in his/her interpretation diffuse axonal injury is present.
CTMRI.CTIschemia 0 == No
1 == Single arterial territory
2 == Multiple territories
3 == Hemisphere
Assessment by clinician/investigator whether or not in his/her interpretation ischemia is present. Only applicable for clinical follow-up CT, not applicable to initial CT. In addition, the severity, in terms of how many arterial territories have ischemia, is requested to be answered.
CTMRI.CTManuf TOSH == Toshiba
SIEM == Siemens
PHIL == Philips
KONI == Konica Minolta
AGFA == Agfa
CARE == Carestream
GE == GE
HITA == Hitachi
99 == Other
This variable describes the CT scans manufacturer.
CTMRI.CTMidlineShift 0 == No
1 == Yes
Assessment by Investigator
CTMRI.CTMidlineShiftMeasure Assessment by Investigator
CTMRI.CTMRICompleteStatus INCNOSHOW == Incompletable - No Show
INCPT == Incompletable - Pt Factors
NOT == Queries Outstanding
COM == Complete
PRO == In Process
NOSTART == Not Started
This variable is populated when the CRF status is "complete".
CTMRI.CTMRIDate Date of Imaging captured in CRF
CTMRI.CTMRITime Time of imaging captured in CRF
CTMRI.CTNoOpMotiv 0 == No surgical lesion
1 == Lesion present, but Acceptable/good neurologic condition
2 == Lesion present, but Guideline adherence
3 == Lesion present, but Little/no mass effect
4 == Lesion present, but Not hospital policy
5 == Lesion present, but Extremely poor prognosis
6 == Lesion present, but Brain Death
7 == Lesion present, but Old age
8 == Lesion present, but Wish family, relative or Legal representative
88 == Unknown
99 == Lesion present, but Other
WHY question: documents reason for not having an indication for (intra)cranial surgery.
CTMRI.CTNoOpMotivOther Specification, only applicable if "CTMRI.CTNoOpMotiv" was "other"
CTMRI.CTPatientLocation ICU == ICU
ADMIS == Ward/Admission
ED == ER
This variable describes the in-hospital location of the patient when the CT-scan was performed and was not meant to describe the location of the CT-scanner. Three options: ER, Ward/Admission, ICU
CTMRI.CTReason ICUADM88 == Unknown
ICUADM99 == Other
LOP == Lack of improvement
IICP == (Suspicion of) Increasing ICP
CD == Clinical deterioration
POC == Post-operative control
SFU == Standard follow-up
This variable contains the main reason why a CT-scan, during hospital stay, was performed. One of following options: standard follow-up, post-operative control, clinical deterioration, (suspicion of) increasing ICP, lack of improvement, unknown, other (specified in CTMRI.CTReasonOther) The reason for making an early CT-scan/ER scan can be found in: CTMRI.CTERReason
CTMRI.CTReasonOther This variable contains the main reason why a CT-scan, during hospital stay, was performed. When the "other" option was selected in variable CTMRI.CTReason, investigators could write the reason in this free text variable. The reason for making an early CT-scan/ER scan can be found in: CTMRI.CTERReason
CTMRI.CTRiskFactorsERAgeGreatrThanEqual60 This variable describes the presence of risk factors (here: age greater than or equal to 60 years) for structural abnormalities on an early CT/MRI. Information for this variable was meant to be only entered for early CT, when CTMRI.CTERReason = "GCS = 15 + risk factors". However, due to the e-CRF lay-out, it will also be populated for patients with CTMRI.CTERReason is not "GCS = 15 + risk factors" or patients with an MRI.
CTMRI.CTRiskFactorsERAlterationOfConsc This variable describes the presence of risk factors (here: alteration of consciousness) for structural abnormalities on an initial/ER CT/MRI. Information for this variable was meant to be only entered for initial/ER CT, when CTMRI.CTERReason = "GCS = 15 + risk factors". However, due to the e-CRF lay-out, it will also be populated for patients with CTMRI.CTERReason is not "GCS = 15 + risk factors" or patients with an MRI.
CTMRI.CTRiskFactorsERAnticoagTx This variable describes the presence of risk factors (here: use of anticoagulant Tx ) for structural abnormalities on an early CT/MRI. Information for this variable was meant to be only entered for early CT, when CTMRI.CTERReason = "GCS = 15 + risk factors". However due to the e-CRF lay-out, it will also be populated for patients with CTMRI.CTERReason is not "GCS = 15 + risk factors" or patients with an MRI.
CTMRI.CTRiskFactorsERAnyNeuroDef This variable describes the presence of risk factors (here: 'any neurological deficit') for structural abnormalities on an initial/ER CT/MRI. Information for this variable was meant to be only entered for initial/ER CT, when CTMRI.CTERReason = "GCS = 15 + risk factors". However due to the e-CRF lay-out, it will also be populated for patients with CTMRI.CTERReason is not "GCS = 15 + risk factors" or patients with an MRI.
CTMRI.CTRiskFactorsERClinSignsOfFractSkullBaseVault This variable describes the presence of risk factors (here: 'clinical signs of fracture skull base or vault') for structural abnormalities on an initial/ER CT/MRI. Information for this variable was meant to be only entered for initial/ER CT, when CTMRI.CTERReason = "GCS = 15+risk factors". However, due to the e-CRF lay-out, it will also be populated for patients with CTMRI.CTERReason is not "GCS = 15 + risk factors" or patients with an MRI.
CTMRI.CTRiskFactorsERContusionFace This variable describes the presence of risk factors (here: 'contusion of the face') for structural abnormalities on an early CT/MRI. Information for this variable was meant to be only entered for early CT, when CTMRI.CTERReason = "GCS = 15 + risk factors". However due to the e-CRF lay-out, it will also be populated for patients with CTMRI.CTERReason is not "GCS = 15 + risk factors" or patients with an MRI.
CTMRI.CTRiskFactorsERFallFromAnyElev This variable describes the presence of risk factors (here: fall from any elevation) for structural abnormalities on an early CT/MRI. Information for this variable was meant to be only entered for early CT, when CTMRI.CTERReason = "GCS = 15 + risk factors". However, due to the e-CRF lay-out, it will also be populated for patients with CTMRI.CTERReason is not "GCS = 15 + risk factors" or patients with an MRI.
CTMRI.CTRiskFactorsERHeadache This variable describes the presence of risk factors (here: headache) for structural abnormalities on an early CT/MRI. Information for this variable was meant to be only entered for early CT, when CTMRI.CTERReason = "GCS = 15 + risk factors". However, due to the e-CRF lay-out, it will also be populated for patients with CTMRI.CTERReason is not "GCS = 15 + risk factors" or patients with an MRI.
CTMRI.CTRiskFactorsERIntoxication This variable describes the presence of risk factors (here: intoxication) for structural abnormalities on an initial/ER CT/MRI. Information for this variable was meant to be only entered for initial/ER CT, when CTMRI.CTERReason = "GCS = 15+risk factors". However due to the e-CRF lay-out, it will also be populated for patients with CTMRI.CTERReason is not "GCS = 15 + risk factors" or patients with an MRI.
CTMRI.CTRiskFactorsERLOC This variable describes the presence of risk factors (here: loss of consciousness) for structural abnormalities on an initial/ER CT/MRI. Information for this variable was meant to be only entered for initial/ER CT, when CTMRI.CTERReason = "GCS = 15 + risk factors". However, due to the e-CRF lay-out, it will also be populated for patients with CTMRI.CTERReason is not "GCS = 15 + risk factors" or patients with an MRI.
CTMRI.CTRiskFactorsEROther This variable describes the presence of risk factors (other reason, not specified elsewhere) for structural abnormalities on an early CT/MRI. Information for this variable was meant to be only entered for early CT, when CTMRI.CTERReason = "GCS = 15 + risk factors". However, due to the e-CRF lay-out, it will also be populated for patients with CTMRI.CTERReason is not "GCS = 15 + risk factors" or patients with an MRI.
CTMRI.CTRiskFactorsEROtherTxt This variable describes the presence of risk factors (other reason, not specified elsewhere: textfield) for structural abnormalities on an early CT/MRI. Information for this variable was meant to be only entered for early CT, when CTMRI.CTERReason = "GCS = 15 + risk factors". However, due to the e-CRF lay-out, it will also be populated for patients with CTMRI.CTERReason is not "GCS = 15 + risk factors" or patients with an MRI.
CTMRI.CTRiskFactorsERPhysEvidTraumaHeadSkull This variable describes the presence of risk factors (here: physical evidence of trauma to head/skull) for structural abnormalities on an initial/ER CT/MRI. Information for this variable was meant to be only entered for initial/ER CT, when CTMRI.CTERReason = "GCS = 15 + risk factors". However, due to the e-CRF lay-out, it will also be populated for patients with CTMRI.CTERReason is not "GCS = 15 + risk factors" or patients with an MRI.
CTMRI.CTRiskFactorsERPTAGreatrThanEqual4hrs This variable describes the presence of risk factors (here: PTA >= 4 hours) for structural abnormalities on an initial/ER CT/MRI. Information for this variable was meant to be only entered for initial/ER CT, when CTMRI.CTERReason = "GCS = 15 + risk factors". However, due to the e-CRF lay-out, it will also be populated for patients with CTMRI.CTERReason is not "GCS = 15 + risk factors" or patients with an MRI.
CTMRI.CTRiskFactorsERSeizure This variable describes the presence of risk factors (here: seizure) for structural abnormalities on an initial/ER CT/MRI. Information for this variable was meant to be only entered for initial/ER CT, when CTMRI.CTERReason = "GCS = 15 + risk factors". However, due to the e-CRF lay-out, it will also be populated for patients with CTMRI.CTERReason is not "GCS = 15 + risk factors" or patients with an MRI.
CTMRI.CTRiskFactorsERSignsFacialFract This variable describes the presence of risk factors (here: signs of facial fracture) for structural abnormalities on an initial/ER CT/MRI. Information for this variable was meant to be only entered for initial/ER CT, when CTMRI.CTERReason = "GCS = 15 + risk factors". However, due to the e-CRF lay-out, it will also be populated for patients with CTMRI.CTERReason is not "GCS = 15 + risk factors" or patients with an MRI.
CTMRI.CTRiskFactorsERVomit This variable describes the presence of risk factors (here: vomiting) for structural abnormalities on an initial/ER CT/MRI. Information for this variable was meant to be only entered for initial/ER CT, when CTMRI.CTERReason = "GCS = 15 + risk factors". However, due to the e-CRF lay-out, it will also be populated for patients with CTMRI.CTERReason is not "GCS = 15 + risk factors" or patients with an MRI.
CTMRI.CTRiskFactorsERVulnRoadUser This variable describes the presence of risk factors (here: vulnerable road users, like pedestrians or cyclists) for structural abnormalities on an early CT/MRI. Information for this variable was meant to be only entered for early CT, when CTMRI.CTERReason = "GCS = 15 + risk factors". However, due to the e-CRF lay-out, it will also be populated for patients with CTMRI.CTERReason is not "GCS = 15 + risk factors" or patients with an MRI.
CTMRI.CTScannerType 16 == 16-slice
32 == 32-slice
64 == 64-slice
99 == Other
128 == 128-slice
256 == 256-slice
320 == 320-slice
This variable specifies the type of CT-scanner by the number of slices.
CTMRI.CTSchedForOp 0 == No
1 == Yes
Whether or not the patient is scheduled for (intra)cranial surgery. The main aim here is to capture whether the clinical team taking care of the patient sees a neurosurgical indication.
CTMRI.CTSubarachnoidHem 0 == No
1 == Basal
2 == Cortical
3 == Basal and Cortical
Assessment by clinician/investigator whether or not in his/her interpretation subarachnoid hemorrhage is present. In addition, the location of the hemorrhage is requested to be answered.
CTMRI.CTType PCT == Perfusion CT
CTA == CT Angiography
CCT == Contrast CT
NCCT == Non-contrast CT
This variable describes the type of CT scan that has been made. Multiple options can be selected from: Non-contrast CT, Contrast CT, CT Angiography, Perfusion CT.
CTMRI.CTYesOpMotiv 1 == Emergency/life saving
2 == Clinical deterioration
3 == Mass effect on CT
4 == Radiological progression
5 == (Suspicion of) raised ICP
6 == Guideline adherence
7 == To prevent deterioration
8 == Depressed skull fracture
99 == Other
WHY question: documents reason for having an indication for (intra)cranial surgery.
CTMRI.CTYesOpMotivOther
CTMRI.IcometrixImageId Identifier generated for an imaging experiment when images are uploaded from site It's recommended to use: Imaging.CRFIcometrixImageId
CTMRI.IcometrixPassedQA 0 == No
1 == Yes
Status of QA dome on images
CTMRI.IcometrixQADateTime Date and time when central QA was done
CTMRI.IcometrixUploadDateTime Date and time when the images were uploaded from site
CTMRI.InitialDataIcometrix
CTMRI.MRIDone This variable is populated when an MRI has been made. MR studies according to study protocol have been performed by selected sites. In addition, results of any MR performed for clinical reasons are captured in the e-CRF. Many of these clinical MR's have also been uploaded to Icometrix.
CTMRI.MRIERReason ER1 == ER only: Discrepancy between clinical symptomatology and (lack of) CT abnormalities
ER3 == ER only: Instead of CT (limiting radiation exposure)
ER2 == ER only: Suspicion non-metal foreign object
ER4 == ER only: Suspicion spinal cord lesion
88 == Unknown
99 == Other
This variable contains the main reason why an MRI, ultra-early MR (within 72 hrs), was performed. Possible options are ER only: Discrepancy between clinical symptomatology and (lack of) CT abnormalities; suspicion non­metal foreign object; instead of CT (limiting radiation exposure); suspicion spinal cord lesion; unknown; other (further specified in text field CTMRI.MRIERReasonOther. Reasons for clinical MRI's can be found in variable CTMRI.MRIReason
CTMRI.MRIERReasonOther This variable contains the main reason why an MRI, ultra-early MR (within 72 hrs), was performed, when in CTMRI.MRIERReason, the "other" option was chosen. This is a free text field. Reasons for clinical MRI's can be found in variable CTMRI.MRIReason
CTMRI.MRIManuf SIEM == Siemens
PHIL == Philips
GE == GE
TOSH == Toshiba
99 == Other
This variable describes the MRI-scan manufacturer.
CTMRI.MRIPatientLocation ADMIS == Ward/Admission
ED == ER
ICU == ICU
This variable describes the in-hospital location of the patient when the MRI-scan was performed and was not meant to describe the location of the MRI-scanner. Three options: ER, Ward/Admission, ICU
CTMRI.MRIReason ICUADM3 == Detection of brainstem lesions
ICUADM2 == Standard Care
ICUADM1 == Discrepancy between CT and clinical condition
STUDYPROT == Study protocol
88 == Unknown
99 == Other
This variable contains the main reason why an MRI, during hospital stay, was performed. One of following options must be selected: discrepancy between CT and clinical condition, standard care, detection of brainstem lesions, study protocol, unknown, other (specified in CTMRI.MRIReasonOther). The reason for making an early MRI/ER MRI scan can be found in: CTMRI.MRIERReason
CTMRI.MRIReasonOther This variable contains the main reason why an MRI, during hospital stay, was performed, when in the variable CTMRI.MRIReason, the option "other" was chosen. This is a text field. The reason for making an early MRI/ER MRI scan can be found in: CTMRI.MRIERReason
CTMRI.MRIResultPreExistAbnorm 0 == No
1 == Yes
88 == Unknown
This variable describes whether or not there are pre-existing abnormalities present on MRI scan (yes, no, unknown). Assessment by investigator and or physician.
CTMRI.MRIResultTraumaticAbnorm 0 == No
1 == Yes
88 == Unknown
This variable describes whether or not there are traumatic abnormalities present on MRI scan (yes, no, unknown). Assessment by investigator and/or physician.
CTMRI.MRIScannerStrength This variable describes the MRI scanner strength. This is a text field.
CTMRI.MRISequences PWI == PWI
MRSI == MRSI
DTI == DTI
SWI == SWI
GRE == GRE
DWI == DWI
FLAIR == FLAIR
T2 == T2
T1 == T1
99 == Other
This variable describes the MRI sequence. Options are: T1, T2, FLAIR, DWI, GRE, SWI, DTI, MRSI, PWI, Other. Multiple options can be selected.
CTMRI.MRITraumAbnormASDH 0 == No
1 == Yes
88 == Unknown
This variable describes whether or not there is an acute subdural hematoma present on MRI scan (yes, no, unknown). Assessment by investigator and/or physician.
CTMRI.MRITraumAbnormContusion 0 == No
1 == Yes
88 == Unknown
This variable describes whether or not there is a contusion present on MRI scan (yes, no, unknown). Assessment by investigator and/or physician.
CTMRI.MRITraumAbnormDAI 0 == No
1 == Yes
88 == Unknown
This variable describes whether or not there is DAI (diffuse axonal injury) present on MRI scan (yes, no, unknown). Assessment by investigator and/or physician.
CTMRI.MRITraumAbnormDAILesionLocBrainstem 0 == No
1 == Yes
88 == Unknown
This variable describes whether or not there is a brain stem lesion present on MRI scan (yes, no, unknown). Assessment by investigator and/or physician.
CTMRI.MRITraumAbnormDAILesionLocCorpusCallosum 0 == No
1 == Yes
88 == Unknown
This variable describes whether or not there is a corpus callosum lesion present on MRI scan (yes, no, unknown). Assessment by investigator and/or physician.
CTMRI.MRITraumAbnormDAILesionLocDiffuseWhiteMatter 0 == No
1 == Yes
88 == Unknown
This variable describes whether or not there is a lesion in diffuse white matter present on MRI scan (yes, no, unknown). Assessment by investigator and/or physician.
CTMRI.MRITraumAbnormDAINumLesions 1 == 1
2 == 2
3 == 3
4 == 4
5 == >= 5
This variable describes how many DAI lesions are present on MRI scan (1,2,3,4,>=5). Assessment by investigator and/or physician.
CTMRI.MRITraumAbnormEDH 0 == No
1 == Yes
88 == Unknown
This variable describes whether or not there is an epidural hematoma present on MRI scan (yes, no, unknown). Assessment by investigator and/or physician.
CTMRI.MRIType MRI == MRI
MRA == MRA
This variable describes the type of MRI scan that has been made. Options are: MRI, MRA
CTMRI.Timepoint CT Followup == CT Followup
CT Early == CT Early
CT Post-Op == CT Post-Op
MR Early == MR Early
This variable describes the timepoint of imaging. Options are: CT Early, CT Followup, CT Post­Op, MR Early CT early is considered "first CT". A central review was performed on all CT's. When a Central review is not available this can be due to: - Scan uninterpretable - Scan not available/performed/uploaded Reasons for scan not being available included: o Scan performed in referring hospital and images not available o Pediatric patient and MR performed instead of CT (reducing radiation risk) o Patient too uncooperative to undergo scan, and no indication for sedation.
CTMRI.XRayDone This variable is populated when an X-ray angiography has been done.
DailyTIL.TILCCSFDrainageVolume Specification of volume drained, only applicable if "DailyTIL.TILCSFDrainage" was "yes"
DailyTIL.TILCSFDrainage 0 == No
1 == Yes
DailyTIL.TILDailyPhysConcSatisfNotDone Daily physician concerns are documented for 9 aspects rated on a scale of 1 (not concerned) to 10 (very concerned)
DailyTIL.TILDate Interpretation of ICP is not possible without knowledge on the level of therapy intensity employed for ICP control and/or for CPP management. TIL can be recorded in great detail and has commonly been performed on an hourly basis. Such detailed recording however, is resource intensive. Further, ICU practices have changed with most high grade interventions (such as metabolic suppression and temperature manipulation) now being used in a continuous fashion over periods of days or at least a large fraction of a day. Other discrete interventions (such as surgical decompression) happen as a single threshold event rather than as a repeated treatment. Given this context, the use of hourly recording of therapy intensity may be less relevant and there are doubts as to whether the data provided by hourly recording of TIL justifies the investment in time, particularly in the context of an increased (and probably increasing) burden of data collection in other areas (such as imaging and biomarkers). We therefore decided to record the therapy intensity level on a daily basis, under the presumption that this will offer a transparent and useful approach with the benefit of a lower burden than when hourly recording is performed. A novel TIL was developed to this purpose, which requires further validation. Preliminary data have been reported by Zuercher et al: Reliability and Validity of the Therapy Intensity Level Scale: Analysis of Clinimetric Properties of a Novel Approach to Assess Management of Intracranial Pressure in Traumatic Brain Injury; J Neurotrauma. 2016 Oct 1;33(19):1768-1774. Epub 2016 Feb 11. The specified treatment modalities and categories are compatible with the pediatric TIL proposed by Shore et al.: Shore P, Adelson PD, Kochanek P, et al. Reliability and validity of the pediatric intensity level of therapy (pilot) scale: A measure of the use of intracranial pressure-directed therapies. Crit Care Med. 2006;34:1981-1987. Possible chasnges in TIL over a 24 hr period are captured in the reporting of "hourly" values at 4 hr intervals.
DailyTIL.TILDobutamineDose Calculated over a 24-hour period
DailyTIL.TILDopamineDose Calculated over a 24-hour period
DailyTIL.TILFactorsCaloricIntakeEnteralKcal
DailyTIL.TILFactorsCaloricIntakeParenKcal
DailyTIL.TILFactorsCaloricIntakeRouteEnteral Enteral route
DailyTIL.TILFactorsCaloricIntakeRouteParen Parenteral The variables "parenteral" and "enteral route" are used to document if the patient received enteral feeding or not and if so, what the total number of Kcal was given by each route.
DailyTIL.TILFactorsCoagHemoglobAfterOtherUnitAmt
DailyTIL.TILFactorsCoagHemoglobAfterOtherUnitSpecify 1 == mmol/L
99 == Other
DailyTIL.TILFactorsCoagHemoglobBeforeOtherUnitAmt
DailyTIL.TILFactorsCoagHemoglobBeforeOtherUnitSpecify 1 == mmol/L
99 == Other
DailyTIL.TILFactorsCoagulation 0 == No
1 == Yes, for clinical reasons
2 == Yes, according to study protocol
88 == Unknown
A maximum of 4 "types" of treatment (drop down box) can be selected and entered under treatment 1-4. Details on volume/dose of the products administered should correspond to treatment 1-4 and be entered in the variable volume 1-4.
DailyTIL.TILFactorsCoagulationHemoglobinAfter
DailyTIL.TILFactorsCoagulationHemoglobinAfterNotDone Intended to document hemoglobin levels after blood transfusion, this variable would indicate that hemoglobin levels were not documented after transfusion; however, some investigators may have also marked this for patients who did not receive a blood transfusion
DailyTIL.TILFactorsCoagulationHemoglobinBefore
DailyTIL.TILFactorsCoagulationHemoglobinBeforeNotDone Intended to be only applicable in case the patient received a blood transfusion, however various investigators may have entered "not done", also for patient who did not receive a transfusion
DailyTIL.TILFactorsCoagulationType1 1 == Packed red blood cell concentrates (pRBCs)
2 == Fresh whole blood
3 == Fresh frozen plasma (FFP)
4 == Freeze dried plasma / lypholized plasma
5 == Platelet concentrates
6 == PCC (prothrombin complex concentrates)
7 == Fibrinogen concentrate
8 == Albumine
9 == Recombinant factor FVIIa
10 == Tranexamic acid (TXA)
11 == Cryoprecipitate
12 == Desmopression (DDAVP)
13 == Factor XIII
14 == Calcium
DailyTIL.TILFactorsCoagulationType2 1 == Packed red blood cell concentrates (pRBCs)
2 == Fresh whole blood
3 == Fresh frozen plasma (FFP)
4 == Freeze dried plasma / lypholized plasma
5 == Platelet concentrates
6 == PCC (prothrombin complex concentrates)
7 == Fibrinogen concentrate
8 == Albumine
9 == Recombinant factor FVIIa
10 == Tranexamic acid (TXA)
11 == Cryoprecipitate
12 == Desmopression (DDAVP)
13 == Factor XIII
14 == Calcium
DailyTIL.TILFactorsCoagulationType3 1 == Packed red blood cell concentrates (pRBCs)
2 == Fresh whole blood
3 == Fresh frozen plasma (FFP)
4 == Freeze dried plasma / lypholized plasma
5 == Platelet concentrates
6 == PCC (prothrombin complex concentrates)
7 == Fibrinogen concentrate
8 == Albumine
9 == Recombinant factor FVIIa
10 == Tranexamic acid (TXA)
11 == Cryoprecipitate
12 == Desmopression (DDAVP)
13 == Factor XIII
14 == Calcium
DailyTIL.TILFactorsCoagulationType4 1 == Packed red blood cell concentrates (pRBCs)
2 == Fresh whole blood
3 == Fresh frozen plasma (FFP)
4 == Freeze dried plasma / lypholized plasma
5 == Platelet concentrates
6 == PCC (prothrombin complex concentrates)
7 == Fibrinogen concentrate
8 == Albumine
9 == Recombinant factor FVIIa
10 == Tranexamic acid (TXA)
11 == Cryoprecipitate
12 == Desmopression (DDAVP)
13 == Factor XIII
14 == Calcium
DailyTIL.TILFactorsCoagulationVolume1
DailyTIL.TILFactorsCoagulationVolume2
DailyTIL.TILFactorsCoagulationVolume3
DailyTIL.TILFactorsCoagulationVolume4
DailyTIL.TILFactorsGenSuppCareDone 0 == No
1 == Yes
DailyTIL.TILFactorsGlucoseManagement 0 == No specific therapy
1 == Prophylactic
2 == Insulin administration to correct hyperglycemias
3 == Tight glycemic control (targeting blood glucose levels of 80-110mg/dL [4.4-6.1mmol/L])
DailyTIL.TILFever 0 == No
1 == Yes
DailyTIL.TILFeverHypothermia 0 == No
1 == Yes
DailyTIL.TILFeverMildHypothermia 0 == No
1 == Yes
DailyTIL.TILFluidBalanceNotDone
DailyTIL.TILFluidCalcStartDate
DailyTIL.TILFluidCalcStartTime
DailyTIL.TILFluidCalcStopDate
DailyTIL.TILFluidCalcStopTime
DailyTIL.TILFluidColloids 0 == No
1 == Yes
88 == Unknown
DailyTIL.TILFluidColloidsTotalVolume
DailyTIL.TILFluidColloidsType 1 == Albumin 5%
2 == Albumin 20%
3 == Dextran
4 == Gelatin (e.g. gelofusion)
5 == HES (hydroxyethyl starches)
6 == Tetrastarches (e.g. HES 130/04)
DailyTIL.TILFluidIn Recorded preferably over 24-hour period, exact details to be derived from start and stop date/time for calculation
DailyTIL.TILFluidLoading 0 == No
1 == Yes
DailyTIL.TILFluidLoadingVasopressor 0 == No
1 == Yes
DailyTIL.TILFluidOutCSFDrain
DailyTIL.TILFluidOutGastric
DailyTIL.TILFluidOutOther
DailyTIL.TILFluidOutUrine
DailyTIL.TILFluidsRenalReplacement 0 == No
1 == Yes
DailyTIL.TILHyperosmolarThearpy 0 == No
1 == Yes
DailyTIL.TILHyperosomolarTherapyHigher 0 == No
1 == Yes
DailyTIL.TILHyperosomolarTherapyHypertonicLow 0 == No
1 == Yes
DailyTIL.TILHyperosomolarTherapyMannitolGreater2g 0 == No
1 == Yes
DailyTIL.TILHypertonicSalineDose Calculated over a 24-hour period
DailyTIL.TILHyperventilation 0 == No
1 == Yes
DailyTIL.TILHyperventilationIntensive 0 == No
1 == Yes
DailyTIL.TILHyperventilationModerate 0 == No
1 == Yes
DailyTIL.TILICPSurgery 0 == No
1 == Yes
DailyTIL.TILICPSurgeryDecomCranectomy 0 == No
1 == Yes
DailyTIL.TILMannitolDose Calculated over a 24-hour period
DailyTIL.TILNoradrenalineDose Calculated over a 24-hour period
DailyTIL.TILOtherDose
DailyTIL.TILOtherTxt
DailyTIL.TILOtherVaso 0 == No
1 == Yes
DailyTIL.TILPhenylephrineDose Calculated over a 24-hour period
DailyTIL.TILPhysicianConcernsContusionpregression 1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
7 == 7
8 == 8
9 == 9
10 == 10
DailyTIL.TILPhysicianConcernsCPP 1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
7 == 7
8 == 8
9 == 9
10 == 10
DailyTIL.TILPhysicianConcernsEpilepsy 1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
7 == 7
8 == 8
9 == 9
10 == 10
DailyTIL.TILPhysicianConcernsFocalSwelling 1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
7 == 7
8 == 8
9 == 9
10 == 10
DailyTIL.TILPhysicianConcernsHematomaProgression 1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
7 == 7
8 == 8
9 == 9
10 == 10
DailyTIL.TILPhysicianConcernsHypoperfusion 1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
7 == 7
8 == 8
9 == 9
10 == 10
DailyTIL.TILPhysicianConcernsICP 1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
7 == 7
8 == 8
9 == 9
10 == 10
DailyTIL.TILPhysicianConcernsIntracranialInfection 1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
7 == 7
8 == 8
9 == 9
10 == 10
DailyTIL.TILPhysicianConcernsVasospasm 1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
7 == 7
8 == 8
9 == 9
10 == 10
DailyTIL.TILPhysicianOverallSatisfaction 0 == Not at all
1 == Slightly
2 == Moderately
3 == Quite
4 == Very
This variable aims to capture the overall satisfaction of the physician with the clinical course of this patient; "not at all satisfied" would indicate that the patient did much more poorly than expected; "very satisfied" would indicate that the patient did much better than expected. Physician satisfaction should be assessed on a daily basis,
DailyTIL.TILPhysicianOverallSatisfactionSurvival 1 == Much worse
2 == A little worse
3 == Unchanged
4 == A little better
5 == Much better
This variable aims to capture the opinion of the treating physician as to whether the short time survival change have chnged in comparision to the previous assessment
DailyTIL.TILPhysicianSatICP 1 == Not at all
2 == Slightly
3 == Moderate
4 == Quite
5 == Very
77 == N/A (no ICP monitoring)
Documents physician satisfaction with ICP control
DailyTIL.TILPosition 0 == No
1 == Yes
DailyTIL.TILPositionNursedFlat 0 == No
1 == Yes
DailyTIL.TILReasonForChange 0 == No change
1 == Intensified: Clinical deterioration
2 == Intensified:Suspicion of increased of ICP (not measured)
3 == Intensified:Increased ICP (documented)
4 == Intensified:Clinical decision to target other mechanism
5 == Intensified:Change of doctor (different shift)
6 == Decreasing:Clinical improvement
7 == Decreasing:Adequate control over ICP
8 == Decreasing:Upper treatment limit reached/past
9 == Decreasing:Further treatment considered futile
10 == Decreasing:Change of doctor (different shift)
DailyTIL.TILSedation 0 == No
1 == Yes
DailyTIL.TILSedationHigher 0 == No
1 == Yes
DailyTIL.TILSedationMetabolic 0 == No
1 == Yes
DailyTIL.TILSedationNeuromuscular 0 == No
1 == Yes
DailyTIL.TILSedationScaleUsed 0 == No
1 == Yes
77 == N/A
DailyTIL.TILSedativesInterrupted 0 == No
1 == Yes
77 == N/A
DailyTIL.TILTherapyIntensityNotDone
DailyTIL.TILTime
DailyTIL.TotalTIL Calculated centrally - 24 hour TILS as the worst sum TILs for each day for the ICU timepoints (day 1-7, 10, 14, 21 and 28)
FollowUp.CTAngulation 1 == No angulation (volume scan)
2 == Orbital-meatal line
99 == Other
FollowUp.CTAtrophy 0 == No
D == Diffuse
F == Focal
88 == Unknown
Scored by investigator
FollowUp.CTHydrocephalus 0 == No
1 == Yes
88 == Unknown
Scored by investigator
FollowUp.CTManuf AGFA == Agfa
CARE == Carestream
GE == GE
HITA == Hitachi
KONI == Konica Minolta
PHIL == Philips
SIEM == Siemens
TOSH == Toshiba
99 == Other
Manufacturer of the CT scanner used
FollowUp.CTMidlineShift 0 == No
1 == Yes
Scored by investigator
FollowUp.CTMidlineShiftMeasure Scored by investigator
FollowUp.CTMRIDate Imaging date captured in the CRF for followup images
FollowUp.CTMRITime Imaging time captured in CRF for followup images
FollowUp.CTReason RFU == Routine follow-up
LOP == Absence of or slow improvement
CD == Clinical deterioration
Reason for follow up CT could be: Clinical deterioration, Absence of or slow improvement, Routine follow­up
FollowUp.CTScannerType 16 == 16-slice
32 == 32-slice
64 == 64-slice
99 == Other
128 == 128-slice
256 == 256-slice
320 == 320-slice
Type of scanner used for follow up CT
FollowUp.CTSubduralHaematomaHygroma 0 == No
R == Right
L == Left
B == Bilateral
88 == Unknown
Scored by investigator
FollowUp.CTType NCCT == Non-contrast CT
CCT == Contrast CT
CTA == CT Angiography
PCT == Perfusion CT
Type of CT scan for followup imaging
FollowUp.FUAttendance 0 == No attendance
1 == Subject
2 == Proxy (please specify)
3 == Health care professional taking care of patient
4 == N/A (death)
Documents who was present at the follow-up assessment. In case of postal Questionnaire, there would be "no attendance"
FollowUp.FUAttendanceProxyChild When a proxy was attending the Follow up visit, specification was needed whether this was: child, parent, partner, sibling or other caretaker. This variable reflects who often the proxy attending the follow up visit was the child of the patient.
FollowUp.FUAttendanceProxyOtherCaretaker When a proxy was attending the Follow up visit, specification was needed whether this was: child, parent, partner, sibling or other caretaker. This variable reflects who often the proxy attending the follow up visit was an other caretaker.
FollowUp.FUAttendanceProxyParent When a proxy was attending the Follow up visit, specification was needed whether this was: child, parent, partner, sibling or other caretaker. This variable reflects who often the proxy attending the follow up visit was a parent of the patient.
FollowUp.FUAttendanceProxyPartner When a proxy was attending the Follow up visit, specification was needed whether this was: child, parent, partner, sibling or other caretaker. This variable reflects who often the proxy attending the follow up visit was the partner of the patient.
FollowUp.FUAttendanceProxySibling When a proxy was attending the Follow up visit, specification was needed whether this was: child, parent, partner, sibling or other caretaker. This variable reflects who often the proxy attending the follow up visit was a sibling of the patient.
FollowUp.FUDisabilityDueToExtracranialInj 0 == No
1 == Mild/moderate
2 == Severe (requiring institutional care)
The variable is only valid when "FollowUp.FUVitStatus" is "alive". It reflects if the patient suffers from any disability due to an extracranial injury
FollowUp.FUImagingModality CT == CT
MRI == MRI
XRay == X-Ray Angiography
The variables concerning imaging modality, largely overlap with those with the in-hospital phase, however details of recording abnormalities and reasons for performing the imaging studies differ
FollowUp.FUIntracranialSurg 0 == No
1 == Yes
88 == Unknown
FollowUp.FUIntracranialSurgDate
FollowUp.FUIntracranialSurgOther
FollowUp.FUIntracranialSurgSpecifyType 1 == Hydrocephalus
2 == Chronic subdural hematoma
3 == Cranioplasty
99 == Other
This variable aims to capture any form of intracranial surgery performed after discharge (re-admission likely)
FollowUp.FUIntracranialSurgTime
FollowUp.FUMartlPartnerStatus 1 == Never been married
2 == Married
3 == Living together/common law
4 == Divorced
5 == Separated
6 == Widowed
88 == Unknown
99 == Other
Only recorded if change in SES; This variable needs to be related to the pre-injury situation: Subject.MartlPartnerStatus
FollowUp.FUMedAmantidine
FollowUp.FUMedAmantidineReason 1 == Agitation
2 == Attentional problems
3 == Behavioral disturbance
4 == Depression
5 == Memory difficulties
6 == Disorder of consciousness
7 == Fatigue
8 == Infection
9 == Pain - somatic
10 == Pain - neurogenic
11 == Pain - headache/migraine
12 == Paroxysmal sympathetic hyperactivity (PSH)
13 == Seizure - prophylaxis
14 == Seizure - treatment
15 == Spasticity
FollowUp.FUMedAntibiotics
FollowUp.FUMedAntibioticsReason 1 == Agitation
2 == Attentional problems
3 == Behavioral disturbance
4 == Depression
5 == Memory difficulties
6 == Disorder of consciousness
7 == Fatigue
8 == Infection
9 == Pain - somatic
10 == Pain - neurogenic
11 == Pain - headache/migraine
12 == Paroxysmal sympathetic hyperactivity (PSH)
13 == Seizure - prophylaxis
14 == Seizure - treatment
15 == Spasticity
FollowUp.FUMedAntiConv
FollowUp.FUMedAntiConvReason 1 == Agitation
2 == Attentional problems
3 == Behavioral disturbance
4 == Depression
5 == Memory difficulties
6 == Disorder of consciousness
7 == Fatigue
8 == Infection
9 == Pain - somatic
10 == Pain - neurogenic
11 == Pain - headache/migraine
12 == Paroxysmal sympathetic hyperactivity (PSH)
13 == Seizure - prophylaxis
14 == Seizure - treatment
15 == Spasticity
FollowUp.FUMedAntidep
FollowUp.FUMedAntidepReason 1 == Agitation
2 == Attentional problems
3 == Behavioral disturbance
4 == Depression
5 == Memory difficulties
6 == Disorder of consciousness
7 == Fatigue
8 == Infection
9 == Pain - somatic
10 == Pain - neurogenic
11 == Pain - headache/migraine
12 == Paroxysmal sympathetic hyperactivity (PSH)
13 == Seizure - prophylaxis
14 == Seizure - treatment
15 == Spasticity
FollowUp.FUMedAntipsycho
FollowUp.FUMedAntipsychoReason 1 == Agitation
2 == Attentional problems
3 == Behavioral disturbance
4 == Depression
5 == Memory difficulties
6 == Disorder of consciousness
7 == Fatigue
8 == Infection
9 == Pain - somatic
10 == Pain - neurogenic
11 == Pain - headache/migraine
12 == Paroxysmal sympathetic hyperactivity (PSH)
13 == Seizure - prophylaxis
14 == Seizure - treatment
15 == Spasticity
FollowUp.FUMedAnxiolytics
FollowUp.FUMedAnxiolyticsReason 1 == Agitation
2 == Attentional problems
3 == Behavioral disturbance
4 == Depression
5 == Memory difficulties
6 == Disorder of consciousness
7 == Fatigue
8 == Infection
9 == Pain - somatic
10 == Pain - neurogenic
11 == Pain - headache/migraine
12 == Paroxysmal sympathetic hyperactivity (PSH)
13 == Seizure - prophylaxis
14 == Seizure - treatment
15 == Spasticity
FollowUp.FUMedCholinergic
FollowUp.FUMedCholinergicReason 1 == Agitation
2 == Attentional problems
3 == Behavioral disturbance
4 == Depression
5 == Memory difficulties
6 == Disorder of consciousness
7 == Fatigue
8 == Infection
9 == Pain - somatic
10 == Pain - neurogenic
11 == Pain - headache/migraine
12 == Paroxysmal sympathetic hyperactivity (PSH)
13 == Seizure - prophylaxis
14 == Seizure - treatment
15 == Spasticity
FollowUp.FUMedClonidine
FollowUp.FUMedClonidineReason 1 == Agitation
2 == Attentional problems
3 == Behavioral disturbance
4 == Depression
5 == Memory difficulties
6 == Disorder of consciousness
7 == Fatigue
8 == Infection
9 == Pain - somatic
10 == Pain - neurogenic
11 == Pain - headache/migraine
12 == Paroxysmal sympathetic hyperactivity (PSH)
13 == Seizure - prophylaxis
14 == Seizure - treatment
15 == Spasticity
FollowUp.FUMedComplAutonomicInstability 0 == No
1 == Yes
88 == Unknown
FollowUp.FUMedComplAutonomicInstabilityTreatment BPUMP == Baclofen pump
DRUGS == Drugs
FollowUp.FUMedComplDVT 0 == No
1 == Yes
88 == Unknown
DVT: Deep venous thrombosis; intent is to record here only DVT occurring post-discharge. DVT that occurred before/at presentation or during hospital stay is recorded alsewhere: Hospital.HospComplDVT
FollowUp.FUMedComplHeteroOss 0 == No
1 == Yes
88 == Unknown
FollowUp.FUMedComplHeteroOssTreatment PLAN == Planned
PERF == Performed
FollowUp.FUMedComplPressureSores 0 == No
1 == Yes
88 == Unknown
FollowUp.FUMedComplPulmonaryEmbolus 0 == No
1 == Yes
88 == Unknown
Intent is to record here only Pulmonary embolism (PE) occurring post-discharge. PE that occurred before/at presentation or during hospital stay is recorded alsewhere: Hospital.HospComplPumlEmb
FollowUp.FUMedComplSeizurePostDischarge 0 == No
1 == Yes
88 == Unknown
Intent is to record here only seizures occurring post-discharge.seizures that occurred before/at presentation or during hospital stay are recorded alsewhere: InjuryHx.EDComplEventSeizures; Vitals.HosComplEventSeizures; Hospital.HospComplSeizures; Vitals.HosComplEventSeizures; Hospital.ICUDisComplSeizure; Outcomes.GOSEEpilepsyFits; Subjective reporting also in: Outcomes.PartQuestACurHltSeiz
FollowUp.FUMedComplSpasticity 0 == No
1 == Yes
88 == Unknown
FollowUp.FUMedComplSpasticityTreatment PHYS == Physiotherapy
IBAC == Intrathecal baclofen pump
OBAC == Oral baclofen
BENZ == Benzodiazepines
FollowUp.FUMedication 0 == No
1 == Yes
88 == Unknown
On Follow-up assessment, general information is captured on classes of medication taken and the reason for taking this. No specific info on agent or dose is captured.
FollowUp.FUMedNarc
FollowUp.FUMedNarcReason 1 == Agitation
2 == Attentional problems
3 == Behavioral disturbance
4 == Depression
5 == Memory difficulties
6 == Disorder of consciousness
7 == Fatigue
8 == Infection
9 == Pain - somatic
10 == Pain - neurogenic
11 == Pain - headache/migraine
12 == Paroxysmal sympathetic hyperactivity (PSH)
13 == Seizure - prophylaxis
14 == Seizure - treatment
15 == Spasticity
FollowUp.FUMedOther
FollowUp.FUMedOtherPain
FollowUp.FUMedOtherPainReason 1 == Agitation
2 == Attentional problems
3 == Behavioral disturbance
4 == Depression
5 == Memory difficulties
6 == Disorder of consciousness
7 == Fatigue
8 == Infection
9 == Pain - somatic
10 == Pain - neurogenic
11 == Pain - headache/migraine
12 == Paroxysmal sympathetic hyperactivity (PSH)
13 == Seizure - prophylaxis
14 == Seizure - treatment
15 == Spasticity
FollowUp.FUMedOtherReason 1 == Agitation
2 == Attentional problems
3 == Behavioral disturbance
4 == Depression
5 == Memory difficulties
6 == Disorder of consciousness
7 == Fatigue
8 == Infection
9 == Pain - somatic
10 == Pain - neurogenic
11 == Pain - headache/migraine
12 == Paroxysmal sympathetic hyperactivity (PSH)
13 == Seizure - prophylaxis
14 == Seizure - treatment
15 == Spasticity
FollowUp.FUMedOtherText
FollowUp.FUMedPsycho
FollowUp.FUMedPsychoReason 1 == Agitation
2 == Attentional problems
3 == Behavioral disturbance
4 == Depression
5 == Memory difficulties
6 == Disorder of consciousness
7 == Fatigue
8 == Infection
9 == Pain - somatic
10 == Pain - neurogenic
11 == Pain - headache/migraine
12 == Paroxysmal sympathetic hyperactivity (PSH)
13 == Seizure - prophylaxis
14 == Seizure - treatment
15 == Spasticity
FollowUp.FUMedSteroids
FollowUp.FUMedSteroidsReason 1 == Agitation
2 == Attentional problems
3 == Behavioral disturbance
4 == Depression
5 == Memory difficulties
6 == Disorder of consciousness
7 == Fatigue
8 == Infection
9 == Pain - somatic
10 == Pain - neurogenic
11 == Pain - headache/migraine
12 == Paroxysmal sympathetic hyperactivity (PSH)
13 == Seizure - prophylaxis
14 == Seizure - treatment
15 == Spasticity
FollowUp.FUPrincipalDeathCause 1 == Head injury/initial injury
2 == Head injury/secondary intracranial damage
3 == Systemic trauma
4 == Medical complications
88 == Unknown
99 == Other
FollowUp.FUPrincipalDeathCauseOther
FollowUp.FUPtStillInICU This variable reflects if the patient was still in ICU at the time of a scheduled follow up visit.
FollowUp.FUReasonNoAttendance 1 == Not contactable
2 == Forgotten
3 == Refused
99 == Other
Documents reason if subject did not undergo assessment
FollowUp.FURehabGenLongTermAcuteCUInPat
FollowUp.FURehabGenRehabUnitInPat
FollowUp.FURehabGeriatricRehabUnitInPat
FollowUp.FURehabInPat Documents that patient received in-patient rehab care at the time of this assessment.
FollowUp.FURehabInPatAdmisDate
FollowUp.FURehabInPatDischDate
FollowUp.FURehabInPatOngoingRehab 0 == No
1 == Yes
FollowUp.FURehabInPatShortTermInterrup1EndDate Only applicable in case the inpatient rehab was interrupted for specific reasons
FollowUp.FURehabInPatShortTermInterrup1StartDate Only applicable in case the inpatient rehab was interrupted for specific reasons
FollowUp.FURehabInPatShortTermInterrup2EndDate Only applicable in case the inpatient rehab was interrupted for specific reasons
FollowUp.FURehabInPatShortTermInterrup2StartDate Only applicable in case the inpatient rehab was interrupted for specific reasons
FollowUp.FURehabInPatShortTermInterrup3EndDate Only applicable in case the inpatient rehab was interrupted for specific reasons
FollowUp.FURehabInPatShortTermInterrup3StartDate Only applicable in case the inpatient rehab was interrupted for specific reasons
FollowUp.FURehabNo Documents that patient received no rehab at the time of this assessment.
FollowUp.FURehabOutPat Documents that patient received out-patient rehab care at the time of this assessment.
FollowUp.FURehabOutPatAdmisDate
FollowUp.FURehabOutPatTherpyCog
FollowUp.FURehabOutPatTherpyCogFreq 1 == 1 - None
2 == 2 - Only follow-up, no active treatment
3 == 3 - < Once a week
4 == 4 - Weekly
5 == 5 - 2-3 times/week
6 == 6 - Daily
7 == 7 - Unknown
FollowUp.FURehabOutPatTherpyCompDayTreatmnt
FollowUp.FURehabOutPatTherpyCompDayTreatmntFreq 1 == 1 - None
2 == 2 - Only follow-up, no active treatment
3 == 3 - < Once a week
4 == 4 - Weekly
5 == 5 - 2-3 times/week
6 == 6 - Daily
7 == 7 - Unknown
FollowUp.FURehabOutPatTherpyHomeHealth
FollowUp.FURehabOutPatTherpyHomeHealthFreq 1 == 1 - None
2 == 2 - Only follow-up, no active treatment
3 == 3 - < Once a week
4 == 4 - Weekly
5 == 5 - 2-3 times/week
6 == 6 - Daily
7 == 7 - Unknown
FollowUp.FURehabOutPatTherpyIndLivngTrainng
FollowUp.FURehabOutPatTherpyIndLivngTrainngFreq 1 == 1 - None
2 == 2 - Only follow-up, no active treatment
3 == 3 - < Once a week
4 == 4 - Weekly
5 == 5 - 2-3 times/week
6 == 6 - Daily
7 == 7 - Unknown
FollowUp.FURehabOutPatTherpyNursServ
FollowUp.FURehabOutPatTherpyNursServFreq 1 == 1 - None
2 == 2 - Only follow-up, no active treatment
3 == 3 - < Once a week
4 == 4 - Weekly
5 == 5 - 2-3 times/week
6 == 6 - Daily
7 == 7 - Unknown
FollowUp.FURehabOutPatTherpyOcc
FollowUp.FURehabOutPatTherpyOccFreq 1 == 1 - None
2 == 2 - Only follow-up, no active treatment
3 == 3 - < Once a week
4 == 4 - Weekly
5 == 5 - 2-3 times/week
6 == 6 - Daily
7 == 7 - Unknown
FollowUp.FURehabOutPatTherpyOther
FollowUp.FURehabOutPatTherpyOtherFreq 1 == 1 - None
2 == 2 - Only follow-up, no active treatment
3 == 3 - < Once a week
4 == 4 - Weekly
5 == 5 - 2-3 times/week
6 == 6 - Daily
7 == 7 - Unknown
FollowUp.FURehabOutPatTherpyOtherText
FollowUp.FURehabOutPatTherpyPeerMentor
FollowUp.FURehabOutPatTherpyPeerMentorFreq 1 == 1 - None
2 == 2 - Only follow-up, no active treatment
3 == 3 - < Once a week
4 == 4 - Weekly
5 == 5 - 2-3 times/week
6 == 6 - Daily
7 == 7 - Unknown
FollowUp.FURehabOutPatTherpyPhysicianInvolved 0 == No
1 == Yes
88 == Unknown
FollowUp.FURehabOutPatTherpyPsychSer
FollowUp.FURehabOutPatTherpyPsychSerFreq 1 == 1 - None
2 == 2 - Only follow-up, no active treatment
3 == 3 - < Once a week
4 == 4 - Weekly
5 == 5 - 2-3 times/week
6 == 6 - Daily
7 == 7 - Unknown
FollowUp.FURehabOutPatTherpyPT
FollowUp.FURehabOutPatTherpyPTFreq 1 == 1 - None
2 == 2 - Only follow-up, no active treatment
3 == 3 - < Once a week
4 == 4 - Weekly
5 == 5 - 2-3 times/week
6 == 6 - Daily
7 == 7 - Unknown
FollowUp.FURehabOutPatTherpyRec
FollowUp.FURehabOutPatTherpyRecFreq 1 == 1 - None
2 == 2 - Only follow-up, no active treatment
3 == 3 - < Once a week
4 == 4 - Weekly
5 == 5 - 2-3 times/week
6 == 6 - Daily
7 == 7 - Unknown
FollowUp.FURehabOutPatTherpySocWrkCaseMgmt
FollowUp.FURehabOutPatTherpySocWrkCaseMgmtFreq 1 == 1 - None
2 == 2 - Only follow-up, no active treatment
3 == 3 - < Once a week
4 == 4 - Weekly
5 == 5 - 2-3 times/week
6 == 6 - Daily
7 == 7 - Unknown
FollowUp.FURehabOutPatTherpySpeech
FollowUp.FURehabOutPatTherpySpeechFreq 1 == 1 - None
2 == 2 - Only follow-up, no active treatment
3 == 3 - < Once a week
4 == 4 - Weekly
5 == 5 - 2-3 times/week
6 == 6 - Daily
7 == 7 - Unknown
FollowUp.FURehabOutPatTherpyStructure 1 == Mono-disciplinary (little/nocollaboration between care providers
2 == Multi-disciplinary
FollowUp.FURehabOutPatTherpyUnknown
FollowUp.FURehabOutPatTherpyUnknownFreq 1 == 1 - None
2 == 2 - Only follow-up, no active treatment
3 == 3 - < Once a week
4 == 4 - Weekly
5 == 5 - 2-3 times/week
6 == 6 - Daily
7 == 7 - Unknown
FollowUp.FURehabOutPatTherpyVocServ
FollowUp.FURehabOutPatTherpyVocServFreq 1 == 1 - None
2 == 2 - Only follow-up, no active treatment
3 == 3 - < Once a week
4 == 4 - Weekly
5 == 5 - 2-3 times/week
6 == 6 - Daily
7 == 7 - Unknown
FollowUp.FURehabTBIRehabUnitInPat
FollowUp.FURehabTherpyEndDate
FollowUp.FURehabTherpyOngoingInd 0 == No
1 == Yes
FollowUp.FURehabUnknown
FollowUp.FUResdncType 1 == Living at home independently
2 == Living at home supported by family/carers
6 == Living in a long-stay patient ward(hospital)
7 == Rehabilitation centre
10 == Living in nursing home
11 == Living in shelteed + housing/community care
99 == Other
Only recorded if change in SES
FollowUp.FUResdncTypeOther Only recorded if change in SES
FollowUp.FURtrnToOtherAct 0 == No
1 == Full return to previous level
2 == Reduced level
88 == Unknown
FollowUp.FURtrnWrkSchlStatus NA == N/A
1 == Returned to previous job / school at same level and hours
2 == Unable to work / go to school
5 == Looking for work / go to school
7 == Retired
8 == Returned to previous job / school at increased levels or hours from pre-injury
9 == Returned to previous job / school at reduced level or hours
10 == Change of job / different work or school
11 == Special employment / sheltered employment
88 == Unknown
FollowUp.FUSESChange 0 == No
1 == Yes
88 == Unknown
This variable aims to document any change in socio-economic status following the TBI
FollowUp.FUSESPeopleLivingWith Only recorded if change in SES
FollowUp.FUSESPrimAdultAlone Only recorded if change in SES; These variables need to be related to the pre-injury situation.
FollowUp.FUSESPrimAdultCarerUnrelated Only recorded if change in SES
FollowUp.FUSESPrimAdultChildren Only recorded if change in SES
FollowUp.FUSESPrimAdultOther Only recorded if change in SES
FollowUp.FUSESPrimAdultParents Only recorded if change in SES
FollowUp.FUSESPrimAdultSiblings Only recorded if change in SES
FollowUp.FUSESPrimAdultSignOther Only recorded if change in SES
FollowUp.FUSESPrimAdultSpousePartner Only recorded if change in SES
FollowUp.FUSESPrimAdultUnknown Only recorded if change in SES
FollowUp.FUSurgCranioplastyPerformed 0 == No
1 == Yes
2 == No, but scheduled
Only applicable in case a decompressive craniectomy was performed during the in-hospital period
FollowUp.FUSurgExtracranialSurg 0 == No
1 == Yes
88 == Unknown
FollowUp.FUSurgExtracranialSurgDate
FollowUp.FUSurgExtracranialSurgSpecify
FollowUp.FUSurgExtracranialSurgTime
FollowUp.FUVisitDate
FollowUp.FUVisitTime
FollowUp.FUVisitType SCHED == Scheduled study follow-up
UNSCHED == Unscheduled follow-up
All Follow-up assessments used questionnaire assessments, and at selected pre-specified time points, neuropsychological testing was done during out-patient follow-up. The schedule for assessments was differentiated by stratum. Cross-sectional assessments, including questionnaires and neuropsych, was performed at 6 mnths post injury. Further Questionnaire assessments were schduled as follows: ER stratum: 2-3 weeks and 3 months; Adm stratum: 3 mnths and 12 mnths; ICU stratum: 3 months and 12 months.
FollowUp.FUVitStatus 0 == Dead
1 == Alive
88 == Unknown
This variable reflects the status of the patient at the time of a scheduled follow up visit. The status could be Dead, Alive, Unknown
FollowUp.IcometrixImageId Identifier generated for an imaging experiment when images are uploaded from site It's recommended to use: Imaging.CRFIcometrixImageId
FollowUp.IcometrixPassedQA 0 == No
1 == Yes
FollowUp.IcometrixQADateTime Date and time when central QA was done for followup images
FollowUp.IcometrixUploadDateTime
FollowUp.InitialDataIcometrix
FollowUp.MRIManuf SIEM == Siemens
PHIL == Philips
GE == GE
TOSH == Toshiba
99 == Other
This variable reflects the manufacturer of the MRI scanner used.
FollowUp.MRIReason CR == Clinical routine
ISC == Ischemia
SBL == Suspicious brainstem lesions
LOP == Lack of improvement
CD == Clinical deterioration
SP == Study protocol
88 == Unknown
99 == Other
FollowUp.MRIReasonOther
FollowUp.MRIResultPreExistAbnorm 0 == No
1 == Yes
88 == Unknown
Scored by investigator
FollowUp.MRIResultTraumaticAbnorm 0 == No
1 == Yes
88 == Unknown
Scored by investigator
FollowUp.MRIScannerStrength
FollowUp.MRISequences T1 == T1
T2 == T2
DWI == DWI
FLAIR == FLAIR
GRE == GRE
DTI == DTI
SWI == SWI
MRSI == MRSI
PWI == PWI
99 == Other
FollowUp.MRITraumAbnormASDH 0 == No
1 == Yes
88 == Unknown
Scored by investigator
FollowUp.MRITraumAbnormContusion 0 == No
1 == Yes
88 == Unknown
Scored by investigator
FollowUp.MRITraumAbnormDAI 0 == No
1 == Yes
88 == Unknown
Scored by investigator
FollowUp.MRITraumAbnormDAILesionLocBrainstem 0 == No
1 == Yes
88 == Unknown
Scored by investigator; only applicable if DAI scored "yes"
FollowUp.MRITraumAbnormDAILesionLocCorpusCallosum 0 == No
1 == Yes
88 == Unknown
Scored by investigator; only applicable if DAI scored "yes"
FollowUp.MRITraumAbnormDAILesionLocDiffuseWhiteMatter 0 == No
1 == Yes
88 == Unknown
Scored by investigator; only applicable if DAI scored "yes"
FollowUp.MRITraumAbnormDAINumLesions 1 == 1
2 == 2
3 == 3
4 == 4
5 == >= 5
Scored by investigator; only applicable if DAI scored "yes"
FollowUp.MRITraumAbnormEDH 0 == No
1 == Yes
88 == Unknown
Scored by investigator
FollowUp.MRIType MRI == MRI
MRA == MRA
Type of MRI for followup imaging
FollowUp.TimePoint 2wk == 2 weeks
3mo == 3 months
6mo == 6 months
12mo == 12 months
24mo == 24 months
Follow up timepoints are 2-3 weeks, 3 months, 6 months, 12 months and 24 months. Depending on the stratum and sub-studies of a patient, follow up was performed at some of these time points or at all timepoints. For an overview, please check the SOP Manual.
Hospital.AdditionalStudiesCoag 0 == No
1 == Yes
Intended to provide a definitive documentation if the patient was enrolled in the MR substudy or not. Would need to verify if MR data are indeed available for this patients.
Hospital.AdditionalStudiesECoG 0 == No
1 == Yes
Hospital.AdditionalStudiesEEG 0 == No
1 == Yes
Hospital.AdditionalStudiesTEGRotem 0 == No
1 == Yes
Intended to provide a definitive documentation if the patient was enrolled in the MR substudy or not. Would need to verify if MR data are indeed available for this patients.
Hospital.BrainDeathDate
Hospital.BrainDeathTime
Hospital.ComplCRBSIDateDiagnosis
Hospital.DeadAge 0 == No
1 == Yes
88 == Unknown
Hospital.DeadCoMorbidities 0 == No
1 == Yes
88 == Unknown
Hospital.DeadDeterminationOfBrainDeath 0 == No
1 == Yes
88 == Unknown
Hospital.DeadOrganDonation 0 == No
1 == Yes
88 == Unknown
Hospital.DeadPatWill 0 == No
1 == Yes
88 == Unknown
Hospital.DeadRequestRelatives 0 == No
1 == Yes
88 == Unknown
Hospital.DeadSeverityofTBI 0 == No
1 == Yes
88 == Unknown
Hospital.DeathAutopsy 0 == No
1 == Yes, forensic
2 == Yes, clinical
88 == Unknown
Hospital.DeathCause 1 == Head injury/initial injury
2 == Head injury/secondary intracranial damage
3 == Systemic trauma
4 == Medical complications
99 == Other
Pre-defined early endpoints recorded at ICU or hospital discharge include: neuroworsening (any episode), time to obeying commands, duration of PTA, number of CTs performed and CT progression.
Hospital.DeathCauseOther
Hospital.DischargeStatus 0 == Dead
1 == Alive
88 == Unknown
Assessment by investigator
Hospital.DispHosp 1 == Other hospital
2 == Rehab unit
3 == Nursing home
5 == Home
88 == Unknown
99 == Other
Documents destination upon hospital discharge
Hospital.DispHospOther
Hospital.GCSHospDischargeEyes UN == Unknown
S == Untestable (swollen)
O == Untestable (other)
1 == 1-None
2 == 2-To pain
3 == 3-To speech
4 == 4-Spontaneously
Hospital.GCSHospDischargeMotor UN == Unknown
O == Untestable (Other)
P == Untestable (Deep sedation/paralyzed)
1 == 1-None
2 == 2-Abnormal extension
3 == 3-Abnormal flexion
4 == 4-Normal flexion/withdrawal
5 == 5-Localizes to pain
6 == 6-Obeys command
Hospital.GCSHospDischargeScore
Hospital.GCSHospDischargeVerbal UN == Unknown
T == Untestable (tracheotomy/endotracheal tube)
O == Untestable (Other)
1 == 1-None
2 == 2-Incomprehensible sound
3 == 3-Inappropriate words
4 == 4-Confused
5 == 5-Oriented
Hospital.HospComplCardio 0 == No
1 == Yes
Hospital.HospComplCRBSI 0 == No
1 == Yes
CRBSI: catheter related blood stream infection
Hospital.HospComplDelayedHaema 0 == No
1 == Yes
Hospital.HospComplDVT 0 == No
1 == Yes
DVT: deep venous thrombosis
Hospital.HospComplIntraCranOther 0 == No
1 == Yes
Hospital.HospComplIntraCranOtherTxt
Hospital.HospComplMeningitis 0 == No
1 == Yes
Hospital.HospComplMetabolic 0 == No
1 == Yes
Hospital.HospComplPressureSore 0 == No
1 == Yes
Hospital.HospComplPumlEmb 0 == No
1 == Yes
Hospital.HospComplRasiedICP 0 == No
1 == Yes
Hospital.HospComplResp 0 == No
1 == Yes
Hospital.HospComplSeizures 0 == No
1 == Yes
Hospital.HospComplSystemOther 0 == No
1 == Yes
Hospital.HospComplSystemOtherTxt
Hospital.HospComplUTI 0 == No
1 == Yes
Hospital.HospDischargeBodyWeightkg
Hospital.HospDischargeBodyWeightlbs
Hospital.HospDischargeBodyWeightMeasure 1 == Estimated
2 == Measured
Hospital.HospDischargeBodyWeightUnit 1 == kgs
2 == lbs
Hospital.HospDischargeCTProgression 0 == No
1 == Yes
Hospital.HospDischargeCTProgressionYes 1 == Increase in initial lesion
2 == Development of new lesion
Hospital.HospDischargeNumberCT 0 == No
1 == Yes
Hospital.HospDischargeReason 0 == No institutional care necessary
1 == No institutional care in trauma center necessary
2 == Clinical rehab required but not approved
3 == Waiting list for rehab
4 == Clinical rehab required and approved
5 == No benefit of clinical rehab anticipated
99 == Other
WHY question: documents reason for choice of discharge destination;WHY question: documents reason for choice of hospital discharge destination.
Hospital.HospDischargeReasonOther
Hospital.HospDischargeTimeToObeyCommands
Hospital.HospDischargeTimeToObeyCommandsNotApplic Intended for use in patients who did not improve to obeying commands at the time of discharge. However, some sites may have used this to mark also patients who never had a depression of consciousness, to the extend that they did not obey commands.
Hospital.HospDischDate Hospital discharge:this variable was included also in the ICU form, in particular to record discharge dates for patients discharged directly from the ICU either dead or alive.
Hospital.HospDischPTADays This variable aims to facilitate collection of more information on PTA for subjects who were still in PTA at the time of admission to hospital. For study-broad interpretation of PTA,, the PTA as recorded on discharge from ER should also be taken into consideration: InjuryHx.LOCPTADuration
Hospital.HospDischPTADaysNA This variable could have been interpreted as either patients never having had PTA or alternatively, a patient who did not recover out of PTA by the time of discharge.
Hospital.HospDischPTAOngoing Intended to designate patients who are still in PTA at the moment of discharge of hospital
Hospital.HospDischTime Hospital discharge:this variable was included also in the ICU form, in particular to record discharge dates for patients discharged directly from the ICU either dead or alive.
Hospital.HospNeuroworseEpisode 0 == No
1 == Yes
Hospital.ICDCode1 16 fields available to enter diagnosis as recorded by hospital administration according to ICD codes; applicable to patients admitted/discharged from hospital.
Hospital.ICDCode10
Hospital.ICDCode11
Hospital.ICDCode12
Hospital.ICDCode13
Hospital.ICDCode14
Hospital.ICDCode15
Hospital.ICDCode16
Hospital.ICDCode2 For patients discharged directly from the ER, ICD codes are documented in: InjuryHx.ERDestICDCodes1
Hospital.ICDCode3
Hospital.ICDCode4
Hospital.ICDCode5
Hospital.ICDCode6
Hospital.ICDCode7
Hospital.ICDCode8
Hospital.ICDCode9
Hospital.ICDCodeVersion 9 == ICD-9
10 == ICD-10
Hospital.ICPDevice 1 == Ventricular
2 == Ventricular +inbuilt sensor
3 == Parenchymal
99 == Other
Type of ICP monitoring device used.
Hospital.ICPDeviceOther Free text field with description of which ICP monitoring device was used, in case the device was not listed in the pre-specified list of the CRF. Some patients have had more than one ICP monitoring device, which are listed here.
Hospital.ICPInsDate
Hospital.ICPInsTime
Hospital.ICPMonitorNo Indicates if a patient does not have intracranial pressure (ICP) monitoring. If Hospital.ICPMonitorNo=1, see Hospital.ICUReasonNoICP.
Hospital.ICPMonitorStop 0 == No
1 == Yes
If ICP monitoring has stopped or not. Time and date is found in Hospital.ICPRemTime and Hospital.ICPRemDate. Reason for stopping ICP monitoring is found in Hospital.ICPMonitorStopReason.
Hospital.ICPMonitorStopReasonOther
Hospital.ICPMonitorYes 0 == No
1 == Yes
Indicates if a patient has intracranial pressure (ICP) monitoring. If yes, see Hospital.ICUReasonICP and Hospital.ICPDevice.
Hospital.ICPMontDuration The duration of ICP monitoring. Calculated variable: Hospital.ICPRemDateTime-Hospital.ICPInsDateTime.
Hospital.ICPRemDate Date for stopping ICP monitoring.
Hospital.ICPRemTime Time of stopping ICP monitoring.
Hospital.ICPStopReason 1 == Clinically improved
2 == ICP stable and < 20 mmHg
3 == Monitor/catheter failure
4 == Patient considered unsalvagable
5 == Patient died
99 == Other
Reason for stopping ICP. Also check Hospital.ICPMonitorStop.
Hospital.ICPUnit 1 == ER
2 == OR
3 == Ward
4 == High dependency unit
99 == Other hospital
The type of department the patient was transferred from to the ICU.
Hospital.ICUAdmDate Admission to the ICU. In principle the date of injury; date of enrollment and Date of Admission to ICU will match, but in some cases there can be a difference of 1 or 2 days. For example when a patient was injured late at night, it is possible that the consent was only obtained in the morning, hence the date of Study Enrollment will be 1 day later than the date of injury. Or in some hospitals a patient is kept for 24 hours in observation at the ER in a specific unit before being transferred to ICU or Ward. Hence the Date of Admission to ICU or Ward can be 1 or 2 days later. Or if there is no bed available on ICU or Ward for a patient being injured late at night, there can be a delay in admitting the patient.
Hospital.ICUAdmisStatusHaemoStable 0 == No
1 == Yes
88 == Unknown
Hospital.ICUAdmisStatusIntubated 0 == No
1 == Yes
88 == Unknown
Hospital.ICUAdmisStatusMechVent 0 == No
1 == Yes
88 == Unknown
Hospital.ICUAdmReason 1 == Mechanical ventilation
2 == Frequent neurological observations
3 == Haemodynamic invasive monitoring
4 == Extracranial injuries
5 == Neurological operation
6 == Clinical deterioration
99 == Other
Hospital.ICUAdmReasonOther
Hospital.ICUAdmTime
Hospital.ICUCardiacOutput 0 == No
1 == Yes
Hospital.ICUCatheterICP 0 == No
1 == Yes
Hospital.ICUCatheterICPDate
Hospital.ICUCatheterICPTime
Hospital.ICUCentralVenousPress 0 == No
1 == Yes
Hospital.ICUComplUTI 0 == No
1 == Yes
Hospital.ICUDisAdditionalStudiesCoag 0 == No
1 == Yes
Hospital.ICUDisAdditionalStudiesTEGRotem 0 == No
1 == Yes
Hospital.ICUDischargeICDCode1 The intent here is to register ICD code as recorded in hospital administrative files for patients directly discharged from the ICU. Up to 16 codes can be entered, ICD codes are fuurther captured at ER discharge and at hospital discharge.
Hospital.ICUDischargeICDCode10
Hospital.ICUDischargeICDCode11
Hospital.ICUDischargeICDCode12
Hospital.ICUDischargeICDCode13
Hospital.ICUDischargeICDCode14
Hospital.ICUDischargeICDCode15
Hospital.ICUDischargeICDCode16
Hospital.ICUDischargeICDCode2
Hospital.ICUDischargeICDCode3
Hospital.ICUDischargeICDCode4
Hospital.ICUDischargeICDCode5
Hospital.ICUDischargeICDCode6
Hospital.ICUDischargeICDCode7
Hospital.ICUDischargeICDCode8
Hospital.ICUDischargeICDCode9
Hospital.ICUDischargeICDCodeVersion 9 == 9
10 == 10
Hospital.ICUDischargeStatus 1 == Alive
2 == Dead
88 == Unknown
Documents data on discharge from ICU
Hospital.ICUDischargeTo 1 == General ward
2 == Other ICU
3 == Other hospital
4 == Rehab unit
5 == Home
6 == Nursing home
7 == Step down/high care unit
88 == Unknown
99 == Other
Documents data on discharge from ICU
Hospital.ICUDischargeToOther
Hospital.ICUDischDate
Hospital.ICUDischPTADays
Hospital.ICUDischPTADaysNA
Hospital.ICUDischPTAOngoing
Hospital.ICUDischTime
Hospital.ICUDisComplCardiacArrest 0 == No
1 == Yes
Hospital.ICUDisComplCRBSI 0 == No
1 == Yes
CRBSI: catheter-related bloodstream infection
Hospital.ICUDisComplDVT 0 == No
1 == Yes
DVT: Deep venous thrombosis
Hospital.ICUDisComplIntraCranOther 0 == No
1 == Yes
Hospital.ICUDisComplIntraCranOtherTxt
Hospital.ICUDisComplMeningitis 0 == No
1 == Yes
Hospital.ICUDisComplMetabolic 0 == No
1 == Yes
Hospital.ICUDisComplPE 0 == No
1 == Yes
Hospital.ICUDisComplPressureSores 0 == No
1 == Yes
Hospital.ICUDisComplRaisedICP 0 == No
1 == Yes
Hospital.ICUDisComplRespiratoryFailure 0 == No
1 == Yes
Hospital.ICUDisComplSeizure 0 == No
1 == Yes
Hospital.ICUDisComplSeromaHematoma 0 == No
1 == Yes
Hospital.ICUDisComplSystemOther 0 == No
1 == Yes
Hospital.ICUDisComplSystemOtherTxt
Hospital.ICUDisComplVAP 0 == No
1 == Yes
VAP: Ventilator associated pneumonia
Hospital.ICUDisCTProg 0 == No
1 == Yes
Hospital.ICUDisCTProgYes 1 == Increase in initial lesion
2 == Development of new lesion
Hospital.ICUDishDurVent
Hospital.ICUDishDurVentNA
Hospital.ICUDisNeuroworseEpisode 0 == No
1 == Yes
Hospital.ICUDisNososcomialPneumNum
Hospital.ICUDisNumCT
Hospital.ICUDisPatDeadAtICU 0 == No
1 == Yes
Intended as an introductory question for the following details on withdrawal of treatment, brain death and organ donation
Hospital.ICUDisPneumAntibiotic1StartDate
Hospital.ICUDisPneumAntibiotic2StartDate
Hospital.ICUDisPneumAntibiotic3StartDate
Hospital.ICUDisPneumAntibiotic4StartDate
Hospital.ICUDisPneumAntibioticTreat 0 == No
1 == Yes
Hospital.ICUDisPneumBacteriaSmpl 1 == BAL
2 == Tracheal suction
3 == PDP
4 == Brush
Hospital.ICUDisPneumBloodFiO2pc
Hospital.ICUDisPneumBloodPaCO2mmHg
Hospital.ICUDisPneumBloodPaO2mmHg
Hospital.ICUDisPneumBloodPEPcmH2O
Hospital.ICUDisPneumBloodPF
Hospital.ICUDisPneumChestX 1 == New pneumonia
2 == Modification of an old one
3 == No infiltrate
4 == Diffuse (or patchy) infiltrate
5 == Localized infiltrate
Hospital.ICUDisPneumClinical 1 == Fever >=38degC or hypothermia <=36degC
2 == Purulent trachea aspirations
3 == Leukocytes >=12000/ml or <=4000/ml
Hospital.ICUDisPneumDate The variables on ventilator associated pneumonia concern a substudy initiated by Luciana Mascia for the PROLABI study
Hospital.ICUDisPneumPathogen1
Hospital.ICUDisPneumPathogen1QuantUCFml
Hospital.ICUDisPneumPathogen2
Hospital.ICUDisPneumPathogen2QuantUCFml
Hospital.ICUDisPneumPathogen3
Hospital.ICUDisPneumPathogen3QuantUCFml
Hospital.ICUDisPneumPathogen4
Hospital.ICUDisPneumPathogen4QuantUCFml
Hospital.ICUDisPneumSepsis 0 == No
1 == Yes
Hospital.ICUDisSixMonthOutcomeDate
Hospital.ICUDisSixMonthOutcomeGOS GR == Good Recovery
MD == Moderate Disability
SD == Severe Disability
V == Vegetative state
D == Death
This variable aims to collect information of the anticipated outcome of this patient as determined on discharge from the ICU by the treating physician. Documents the level of experience of physician who provided prognostic estimate on discharge from ICU.
Hospital.ICUDisSixMonthOutcomeQualification 1 == Resident
2 == Junior staff (< 5 years)
3 == Senior staff ( >5 years)
4 == Head of department
Documents the level of experience of physician who provided prognostic estimate on discharge from ICU
Hospital.ICUDisSixMonthOutcomeType 1 == ER physician
2 == Intensive care physician
3 == Neurology
4 == Neurosurgery
5 == Traumatology
88 == Unknown
99 == Other
Documents the specialty of physician who provided prognostic estimate on discharge from ICU
Hospital.ICUDisSixMonthOutcomeUnfavourable
Hospital.ICUDisSupportWithdrawnDate This variable documents date and time at which life prolonging therapy was withdrawn
Hospital.ICUDisSupportWithdrawnTime
Hospital.ICUDisTimeToObeyCommands
Hospital.ICUDisTimeToObeyCommandsNA
Hospital.ICUDisWithdrawalTreatmentDecisionDate Investigators were requested to record the date and time of "a do not resuscitate (DNR)" policy
Hospital.ICUDisWithdrawalTreatmentDecisionTime
Hospital.ICUDisWithdrawlTreatmentDecision 1 == Multi disciplinary
2 == By a single physician
3 == With relatives
Hospital.ICUEndTidalCO2 0 == No
1 == Yes
Hospital.ICUGCSDischargeEyes O == Untestable (other)
S == Untestable (swollen)
1 == 1-None
2 == 2-To pain
3 == 3-To speech
4 == 4-Spontaneously
88 == Unknown
Hospital.ICUGCSDischargeMotor UN == Unknown
P == Untestable (Deep sedation/paralyzed)
O == Untestable (Other)
1 == 1-None
2 == 2-Abnormal extension
3 == 3-Abnormal flexion
4 == 4-Normal flexion/withdrawal
5 == 5-Localizes to pain
6 == 6-Obeys command
Hospital.ICUGCSDischargeScore
Hospital.ICUGCSDischargeVerbal UN == Unknown
O == Untestable (Other)
P == Untestable (tracheotomy/endotracheal tube)
T == Untestable (tracheotomy/endotracheal tube)
1 == 1-None
2 == 2-Incomprehensible sound
3 == 3-Inappropriate words
4 == 4-Confused
5 == 5-Oriented
Hospital.ICUInvasiveBP 0 == No
1 == Yes
Hospital.ICUProblemsICP 0 == No
1 == Yes
Hospital.ICUProblemsICPYes 1 == Accidental catheter removal
2 == Catheter obstruction/failure
3 == Suspicion of inaccurate measurement
Hospital.ICUPulseOximetry 0 == No
1 == Yes
Hospital.ICURaisedICP 0 == No
1 == Yes, controlled
2 == Yes, refractory
Hospital.ICUReasonForTypeICPMont 1 == Routine in our department
2 == Not routine, but enlarged ventricles
3 == No parenchymal device available
99 == Other
WHY Question: reason for choosing ventricular monitor
Hospital.ICUReasonForTypeICPMontPare 1 == Routine in our department
2 == Not routine, but small ventricles
3 == Mainly motivated by time of day
4 == No OR available for placement ventr. catheter
5 == Failed implantation ventricular catheter
99 == Other
WHY Question: reason for choosing parenchymal monitor
Hospital.ICUReasonForTypeICUMontOther
Hospital.ICUReasonForTypeICUMontParOther
Hospital.ICUReasonICP 1 == Guideline criteria
2 == Radiological signs raised ICP
3 == Clinical suspicion raised ICP
4 == Anaesthesia or mechanical ventilation required for extracranial injuries
5 == To inform surgical indication for mass lesion
99 == Other
WHY Question: documents reason for monitoring ICP in patient admitted to ICU
Hospital.ICUReasonICPOther Free text field for description of why the patient has ICP monitoring if there is another reason than pre-specified in Hospital.ICUReasonICP.
Hospital.ICUReasonNoICP 1 == GCS >8
2 == No radiological signs of raised ICP
3 == Risk of raised ICP considered low
4 == Patient considered unsalvageable
5 == Coagulopathy
6 == Use of anticoagulants or platelet aggregation inhibitors
7 == No device available
8 == Not local policy to monitor ICP
9 == Too costly
99 == Other
WHY Question: documents reason for not monitoring ICP in patient admitted to ICU
Hospital.ICUReasonNoICPOther Free text field for description of the reason why ICP has not been monitored in ICU patient if there is another reason than pre-specified in Hospital.ICUReasonNoICP.
Hospital.MonContEGG 0 == No
1 == Yes
Hospital.MonContEGGDuration
Hospital.MonECoG 0 == No
1 == Yes
Hospital.MonECoGDuration
Hospital.MonJugularDesatEpisodes 0 == No
1 == Yes
77 == N/A
Hospital.MonJugularSatDuration
Hospital.MonJugularSatStopReason 1 == Monitor/catheter failure
2 == Patient considered unsalvageable
3 == Patient died
4 == Clinically no longer required
Hospital.MonJugularSatUsed 0 == No
1 == Yes
Hospital.MonLicoxDuration
Hospital.MonLicoxPO2 0 == No
1 == Yes
77 == N/A
Hospital.MonLicoxStopReason 1 == Monitor/catheter failure
2 == Patient considered unsalvageable
3 == Patient died
4 == Clinically no longer required
Hospital.MonLicoxUsed 0 == No
1 == Yes
Hospital.MonMicrodialysisDuration
Hospital.MonMicrodialysisStopReason 1 == Monitor/catheter failure
2 == Patient considered unsalvageable
3 == Patient died
4 == Clinically no longer required
Hospital.MonMicrodialysisUsed 0 == No
1 == Yes
Hospital.MonTranscranDoppler 0 == No
1 == Yes
Hospital.OrganDonationDate
Hospital.OrganDonationTime
Hospital.SixMonthOutcomeDate
Hospital.SixMonthOutcomeGOS GR == Good Recovery
MD == Moderate Disability
SD == Severe Disability
V == Vegetative state
D == Death
Documents the level of experience of physician who provided prognostic estimate on discharge from hospital
Hospital.SixMonthOutcomeQualification 1 == Resident
2 == Junior staff (< 5 years)
3 == Senior staff ( >5 years)
4 == Head of department
Documents the level of experience of physician who provided prognostic estimate on discharge from hospital
Hospital.SixMonthOutcomeType 1 == ER physician
2 == Intensive care physician
3 == Neurology
4 == Neurosurgery
5 == Traumatology
88 == Unknown
99 == Other
Documents the specialty of physician who provided prognostic estimate on discharge from hospital
Hospital.SixMonthOutcomeUnfavourable
Hospital.SupportWithdrawnDate
Hospital.SupportWithdrawnTime
Hospital.TimeSinceICUAdmisDeath
Hospital.WardAdmDate Date of admission to the ward In principle the date of injury; date of enrollment and Date of Admission to Ward will match, but in some cases there can be a difference of 1 or 2 days. For example when a patient was injured late at night, it is possible that the consent was only obtained in the morning, hence the date of Study Enrollment will be 1 day later than the date of injury. Or in some hospitals a patient is kept for 24 hours in observation at the ER in a specific unit before being transferred to ICU or Ward. Hence the Date of Admission to ICU or Ward can be 1 or 2 days later. Or if there is no bed available on ICU or Ward for a patient being injured late at night, there can be a delay in admitting the patient.
Hospital.WardAdmReason 4 == Extracranial injuries
7 == CT abnormalities
8 == Clinical observation for TBI
9 == No ICU bed available
10 == Could be discharged home, but no adequate supervision
99 == Other
WHY question: documents main reason for admission to ward (and not to ICU or discharge home)
Hospital.WardAdmReasonOther If the variable WardAdmReason was set to Other the reason for admission to the ward is filled in here.
Hospital.WardAdmTime Time of admission to the ward
Hospital.WithdrawalTreatmentDecision 1 == Multi disciplinary
2 == By a single physician
3 == With relatives
Intended only to be scored if a medical decision was made to withdraw active treatment because of anticipated poor prognosis. However, some investigators may have scored this when patients had recovered to an extent that active treatment was no longer necessary.
Hospital.WithdrawalTreatmentDecisionDate
Hospital.WithdrawalTreatmentDecisionTime
HourlyMeasurements.DaySinceInjury Calculated from HourlyValues.HVDate and Subject.DateInj
HourlyMeasurements.HVCPP Normalized data for HVCPP2, HVCPP 4 etc. Calculated from MAP-ICP (HVSBP+2*HVDBP)/3-HVICP.
HourlyMeasurements.HVDateTime The date and time manually entered for the measurements in HourlyValues at time 2,4,6... are combined into this variable to match the entries in the HourlyMeasurements variables for HVSBP, HVDBP, HVICP.
HourlyMeasurements.HVDBP All diastolic blood pressures combined into one variable, measured twice hourly. To get intended measurement time, see HourlyMeasurements.HVMeasurementDateTime.
HourlyMeasurements.HVICP All intracranial pressures combined into one variable, measured twice hourly. To get intended measurement time, see HourlyMeasurements.HVMeasurementDateTime.
HourlyMeasurements.HVMeasurementDateTime The intended date and time for all hourly values measurements (HVSBP, HVDBP, HVICP, HVCPP) derived from HVDate+HVTimeX where HVTimeX is HVTime2->02.00, HVTime4->04.00,..., HVTime24->23.59.
HourlyMeasurements.HVSBP All systolic blood pressures combined into one variable, measured twice hourly. To get intended measurement time, see HourlyMeasurements.HVMeasurementDateTime.
HourlyMeasurements.HVTIL Investigators were requested to document any change in TIL at 4 hour intervals (6 times per day), in a way that corresponds with the documentation of hourly values (04:00-08:00-12:00-16:00-20:00-24:00). This variable combines the hourly TIL values and represents in a long format these hourly measurements. See also HourlyValues.HVTIL4, HourlyValues.HVTIL8, HourlyValues.HVTIL12, HourlyValues.HVTIL16, HourlyValues.HVTIL20, HourlyValues.HVTIL24
HourlyValues.HourlyValueAccurate 0 == No
1 == Yes
2 == Doubtful
Are the measured values for ICP over this day considered to be accurate? An explanation can be found in HourlyValues.HourlyValueNotAccurateProblems. Associated with the date in HourlyValues.HVDate.
HourlyValues.HourlyValueICPDiscontinued 0 == No
1 == Yes
Answer to the question: "Was active ICP treatment discontinued (due to poor prognosis)?"
HourlyValues.HourlyValueLevelABP 1 == Right atrium
2 == Level of arterial catheter
99 == Other
Differences in level of zeroing the arterial blood pressure transducer may affect calculations of CPP and comparisons between centres.
HourlyValues.HourlyValueLevelABPOther A free text description of the level of ABP transducer if HourlyValues.HourlyValueLevelABP is "other".
HourlyValues.HourlyValueLevelICP 1 == Foramen of Monro
2 == Same level as ABP
3 == Meatus externus (ear)
Only applicable in case ICP monitored; Differences in level of zeroing ICP may affect calculation of CPP and comparisons between centres.
HourlyValues.HourlyValueNotAccurateProblems Explanation in free text of the variable HourlyValues.HourlyValueAccurate. Associated with the date in HourlyValues.HVDate.
HourlyValues.HVCPP10 The cerebral perfusion pressure, CPP, associated with the HourlyValues.HVDateTime10. Calculated by the equation HVCPP10 = (HVSBP10+ 2*HVDBP10)/3-HVICP10. It is set to NA if any of the values in the equation is missing or HVICP10 is 0.
HourlyValues.HVCPP12 The cerebral perfusion pressure, CPP, associated with the HourlyValues.HVDateTime12. Calculated by the equation HVCPP12 = (HVSBP12+ 2*HVDBP12)/3-HVICP12. It is set to NA if any of the values in the equation is missing or HVICP12 is 0.
HourlyValues.HVCPP14 The cerebral perfusion pressure, CPP, associated with the HourlyValues.HVDateTime14. Calculated by the equation HVCPP14 = (HVSBP14+ 2*HVDBP14)/3-HVICP14. It is set to NA if any of the values in the equation is missing or HVICP14 is 0.
HourlyValues.HVCPP16 The cerebral perfusion pressure, CPP, associated with the HourlyValues.HVDateTime16. Calculated by the equation HVCPP16 = (HVSBP16+ 2*HVDBP16)/3-HVICP16. It is set to NA if any of the values in the equation is missing or HVICP16 is 0.
HourlyValues.HVCPP18 The cerebral perfusion pressure, CPP, associated with the HourlyValues.HVDateTime18. Calculated by the equation HVCPP18 = (HVSBP18+ 2*HVDBP18)/3-HVICP18. It is set to NA if any of the values in the equation is missing or HVICP18 is 0.
HourlyValues.HVCPP2 The cerebral perfusion pressure, CPP, associated with the HourlyValues.HVDateTime2. This variable is calculated by HVCPP2 = (HVSBP2+2*HVDBP2)/3 - HVICP2. It is set to NA if any of the values in the equation is missing or HVICP2 is 0.
HourlyValues.HVCPP20 The cerebral perfusion pressure, CPP, associated with the HourlyValues.HVDateTime20. Calculated by the equation HVCPP20 = (HVSBP20+ 2*HVDBP20)/3-HVICP20. It is set to NA if any of the values in the equation is missing or HVICP20 is 0.
HourlyValues.HVCPP22 The cerebral perfusion pressure, CPP, associated with the HourlyValues.HVDateTime22. Calculated by the equation HVCPP22 = (HVSBP22+ 2*HVDBP22)/3-HVICP22. It is set to NA if any of the values in the equation is missing or HVICP22 is 0.
HourlyValues.HVCPP24 The cerebral perfusion pressure, CPP, associated with the HourlyValues.HVDateTime24. Calculated by the equation HVCPP24 = (HVSBP24+ 2*HVDBP24)/3-HVICP24. It is set to NA if any of the values in the equation is missing or HVICP24 is 0.
HourlyValues.HVCPP4 The cerebral perfusion pressure, CPP, associated with the HourlyValues.HVDateTime4. This variable is calculated by the equation HVCPP4 = (HVSBP4+ 2*HVDBP4)/3-HVICP4. It is set to NA if any of the values in the equation is missing or HVICP2 is 0.
HourlyValues.HVCPP6 The cerebral perfusion pressure, CPP, associated with the HourlyValues.HVDateTime6. Calculated by the equation HVCPP6 = (HVSBP6+ 2*HVDBP6)/3-HVICP6. It is set to NA if any of the values in the equation is missing or HVICP6 is 0.
HourlyValues.HVCPP8 The cerebral perfusion pressure, CPP, associated with the HourlyValues.HVDateTime8. Calculated by the equation HVCPP8 = (HVSBP8+ 2*HVDBP8)/3-HVICP8. It is set to NA if any of the values in the equation is missing or HVICP8 is 0.
HourlyValues.HVDate The date the hourly values are measured.
HourlyValues.HVDBP10 The diastolic blood pressure associated with HourlyValues.HVDateTime10.
HourlyValues.HVDBP12 The diastolic blood pressure associated with HourlyValues.HVDateTime12.
HourlyValues.HVDBP14 The diastolic blood pressure associated with HourlyValues.HVDateTime14.
HourlyValues.HVDBP16 The diastolic blood pressure associated with HourlyValues.HVDateTime16.
HourlyValues.HVDBP18 The diastolic blood pressure associated with HourlyValues.HVDateTime18.
HourlyValues.HVDBP2 The diastolic blood pressure associated with HourlyValues.HVDateTime2.
HourlyValues.HVDBP20 The diastolic blood pressure associated with HourlyValues.HVDateTime20.
HourlyValues.HVDBP22 The diastolic blood pressure associated with HourlyValues.HVDateTime22.
HourlyValues.HVDBP24 The diastolic blood pressure associated with HourlyValues.HVDateTime24.
HourlyValues.HVDBP4 The diastolic blood pressure associated with HourlyValues.HVDateTime4.
HourlyValues.HVDBP6 The diastolic blood pressure associated with HourlyValues.HVDateTime6.
HourlyValues.HVDBP8 The diastolic blood pressure associated with HourlyValues.HVDateTime8.
HourlyValues.HVICP10 The intracranial pressure associated with HourlyValues.HVDateTime10.
HourlyValues.HVICP12 The intracranial pressure associated with HourlyValues.HVDateTime12.
HourlyValues.HVICP14 The intracranial pressure associated with HourlyValues.HVDateTime14.
HourlyValues.HVICP16 The intracranial pressure associated with HourlyValues.HVDateTime16.
HourlyValues.HVICP18 The intracranial pressure associated with HourlyValues.HVDateTime18.
HourlyValues.HVICP2 The intracranial pressure associated with HourlyValues.HVDateTime2.
HourlyValues.HVICP20 The intracranial pressure associated with HourlyValues.HVDateTime20.
HourlyValues.HVICP22 The intracranial pressure associated with HourlyValues.HVDateTime22.
HourlyValues.HVICP24 The intracranial pressure associated with HourlyValues.HVDateTime24.
HourlyValues.HVICP4 The intracranial pressure associated with HourlyValues.HVDateTime4.
HourlyValues.HVICP6 The intracranial pressure associated with HourlyValues.HVDateTime6.
HourlyValues.HVICP8 The intracranial pressure associated with HourlyValues.HVDateTime8.
HourlyValues.HVSBP10 The systolic blood pressure associated with HourlyValues.HVDateTime10.
HourlyValues.HVSBP12 The systolic blood pressure associated with HourlyValues.HVDateTime12.
HourlyValues.HVSBP14 The systolic blood pressure associated with HourlyValues.HVDateTime14.
HourlyValues.HVSBP16 The systolic blood pressure associated with HourlyValues.HVDateTime16.
HourlyValues.HVSBP18 The systolic blood pressure associated with HourlyValues.HVDateTime18.
HourlyValues.HVSBP2 The systolic blood pressure associated with HourlyValues.HVDateTime2.
HourlyValues.HVSBP20 The systolic blood pressure associated with HourlyValues.HVDateTime20.
HourlyValues.HVSBP22 The systolic blood pressure associated with HourlyValues.HVDateTime22.
HourlyValues.HVSBP24 The systolic blood pressure associated with HourlyValues.HVDateTime24.
HourlyValues.HVSBP4 The systolic blood pressure associated with HourlyValues.HVDateTime4.
HourlyValues.HVSBP6 The systolic blood pressure associated with HourlyValues.HVDateTime6.
HourlyValues.HVSBP8 The systolic blood pressure associated with HourlyValues.HVDateTime8.
HourlyValues.HVTIL12 0 == No change
1 == Increasing intensity
2 == Decreasing intensity
Investigators were requested to document any change in TIL at 4 hour intervals (6 times per day), in a way that corresponds with the documentation of hourly values (04:00-08:00-12:00-16:00-20:00-24:00)
HourlyValues.HVTIL16 0 == No change
1 == Increasing intensity
2 == Decreasing intensity
Investigators were requested to document any change in TIL at 4 hour intervals (6 times per day), in a way that corresponds with the documentation of hourly values (04:00-08:00-12:00-16:00-20:00-24:00)
HourlyValues.HVTIL20 0 == No change
1 == Increasing intensity
2 == Decreasing intensity
Investigators were requested to document any change in TIL at 4 hour intervals (6 times per day), in a way that corresponds with the documentation of hourly values (04:00-08:00-12:00-16:00-20:00-24:00)
HourlyValues.HVTIL24 0 == No change
1 == Increasing intensity
2 == Decreasing intensity
Investigators were requested to document any change in TIL at 4 hour intervals (6 times per day), in a way that corresponds with the documentation of hourly values (04:00-08:00-12:00-16:00-20:00-24:00)
HourlyValues.HVTIL4 0 == No change
1 == Increasing intensity
2 == Decreasing intensity
Investigators were requested to document any change in TIL at 4 hour intervals (6 times per day), in a way that corresponds with the documentation of hourly values (04:00-08:00-12:00-16:00-20:00-24:00)
HourlyValues.HVTIL8 0 == No change
1 == Increasing intensity
2 == Decreasing intensity
Investigators were requested to document any change in TIL at 4 hour intervals (6 times per day), in a way that corresponds with the documentation of hourly values (04:00-08:00-12:00-16:00-20:00-24:00)
HourlyValues.HVTILChangeReason12 1 == Intensified: Clinical deterioration
2 == Intensified: Suspicion of increased of ICP (not measured)
3 == Intensified: Increased ICP (documented)
4 == Intensified:Clinical decision to target other mechanism
5 == Intensified:Change of doctor (different shift)
6 == Decreasing:Clinical improvement
7 == Decreasing:Adequate control over ICP
8 == Decreasing:Upper treatment limit reached/past
9 == Decreasing: Further treatment considered futile
10 == Decreasing: Change of doctor (different shift)
HourlyValues.HVTILChangeReason16 1 == Intensified: Clinical deterioration
2 == Intensified: Suspicion of increased of ICP (not measured)
3 == Intensified: Increased ICP (documented)
4 == Intensified:Clinical decision to target other mechanism
5 == Intensified:Change of doctor (different shift)
6 == Decreasing:Clinical improvement
7 == Decreasing:Adequate control over ICP
8 == Decreasing:Upper treatment limit reached/past
9 == Decreasing: Further treatment considered futile
10 == Decreasing: Change of doctor (different shift)
HourlyValues.HVTILChangeReason20 1 == Intensified: Clinical deterioration
2 == Intensified: Suspicion of increased of ICP (not measured)
3 == Intensified: Increased ICP (documented)
4 == Intensified:Clinical decision to target other mechanism
5 == Intensified:Change of doctor (different shift)
6 == Decreasing:Clinical improvement
7 == Decreasing:Adequate control over ICP
8 == Decreasing:Upper treatment limit reached/past
9 == Decreasing: Further treatment considered futile
10 == Decreasing: Change of doctor (different shift)
HourlyValues.HVTILChangeReason24 1 == Intensified: Clinical deterioration
2 == Intensified: Suspicion of increased of ICP (not measured)
3 == Intensified: Increased ICP (documented)
4 == Intensified:Clinical decision to target other mechanism
5 == Intensified:Change of doctor (different shift)
6 == Decreasing:Clinical improvement
7 == Decreasing:Adequate control over ICP
8 == Decreasing:Upper treatment limit reached/past
9 == Decreasing: Further treatment considered futile
10 == Decreasing: Change of doctor (different shift)
HourlyValues.HVTILChangeReason4 1 == Intensified: Clinical deterioration
2 == Intensified: Suspicion of increased of ICP (not measured)
3 == Intensified: Increased ICP (documented)
4 == Intensified:Clinical decision to target other mechanism
5 == Intensified:Change of doctor (different shift)
6 == Decreasing:Clinical improvement
7 == Decreasing:Adequate control over ICP
8 == Decreasing:Upper treatment limit reached/past
9 == Decreasing: Further treatment considered futile
10 == Decreasing: Change of doctor (different shift)
WHY question: Differentiated for: - Intensified: Clinical deterioration - Intensified: Suspicion of increased of ICP - Intensified: increased ICP (documented) - Intensified:Clinical decision to target other mechanism - Intensified:Change of doctor (different shift) - Decreasing:Clinical improvement - Decreasing:Adequate control over ICP - Decreasing:Upper treatment limit reached/past - Decreasing: Further treatment considered futile - Decreasing: Change of doctor (different shift). The hours at which the reasons for change are documented should correspond to the hours for documentation of any change in TIL; documentation of reason is only required in case of a change in TIL
HourlyValues.HVTILChangeReason8 1 == Intensified: Clinical deterioration
2 == Intensified: Suspicion of increased of ICP (not measured)
3 == Intensified: Increased ICP (documented)
4 == Intensified:Clinical decision to target other mechanism
5 == Intensified:Change of doctor (different shift)
6 == Decreasing:Clinical improvement
7 == Decreasing:Adequate control over ICP
8 == Decreasing:Upper treatment limit reached/past
9 == Decreasing: Further treatment considered futile
10 == Decreasing: Change of doctor (different shift)
HourlyValues.HVTime10 Investigators were requested to document hourly values every 2 hours (12 times per day) for all patients receiving ICP monitoring. The timeperiods were pre-specified (02:00-24:00); however, investigators may have entered values at different times and have then entered the time of obtaining hourly values; a possible confusion may exist if investigators entered the time of documenting the hourly values rather than the time at which they were obtained.
HourlyValues.HVTime12 Investigators were requested to document hourly values every 2 hours (12 times per day) for all patients receiving ICP monitoring. The timeperiods were pre-specified (02:00-24:00); however, investigators may have entered values at different times and have then entered the time of obtaining hourly values; a possible confusion may exist if investigators entered the time of documenting the hourly values rather than the time at which they were obtained.
HourlyValues.HVTime14 Investigators were requested to document hourly values every 2 hours (12 times per day) for all patients receiving ICP monitoring. The timeperiods were pre-specified (02:00-24:00); however, investigators may have entered values at different times and have then entered the time of obtaining hourly values; a possible confusion may exist if investigators entered the time of documenting the hourly values rather than the time at which they were obtained.
HourlyValues.HVTime16 Investigators were requested to document hourly values every 2 hours (12 times per day) for all patients receiving ICP monitoring. The timeperiods were pre-specified (02:00-24:00); however, investigators may have entered values at different times and have then entered the time of obtaining hourly values; a possible confusion may exist if investigators entered the time of documenting the hourly values rather than the time at which they were obtained.
HourlyValues.HVTime18 Investigators were requested to document hourly values every 2 hours (12 times per day) for all patients receiving ICP monitoring. The timeperiods were pre-specified (02:00-24:00); however, investigators may have entered values at different times and have then entered the time of obtaining hourly values; a possible confusion may exist if investigators entered the time of documenting the hourly values rather than the time at which they were obtained.
HourlyValues.HVTime2 Investigators were requested to document hourly values every 2 hours (12 times per day) for all patients receiving ICP monitoring. The timeperiods were pre-specified (02:00-24:00); however, investigators were allowed to enter another timepoint in this field.
HourlyValues.HVTime20 Investigators were requested to document hourly values every 2 hours (12 times per day) for all patients receiving ICP monitoring. The timeperiods were pre-specified (02:00-24:00); however, investigators may have entered values at different times and have then entered the time of obtaining hourly values; a possible confusion may exist if investigators entered the time of documenting the hourly values rather than the time at which they were obtained.
HourlyValues.HVTime22 Investigators were requested to document hourly values every 2 hours (12 times per day) for all patients receiving ICP monitoring. The timeperiods were pre-specified (02:00-24:00); however, investigators may have entered values at different times and have then entered the time of obtaining hourly values; a possible confusion may exist if investigators entered the time of documenting the hourly values rather than the time at which they were obtained.
HourlyValues.HVTime24 Investigators were requested to document hourly values every 2 hours (12 times per day) for all patients receiving ICP monitoring. The timeperiods were pre-specified (02:00-24:00); however, investigators may have entered values at different times and have then entered the time of obtaining hourly values; a possible confusion may exist if investigators entered the time of documenting the hourly values rather than the time at which they were obtained.
HourlyValues.HVTime4 Investigators were requested to document hourly values every 2 hours (12 times per day) for all patients receiving ICP monitoring. The timeperiods were pre-specified (02:00-24:00); however, investigators may have entered values at different times and have then entered the time of obtaining hourly values; a possible confusion may exist if investigators entered the time of documenting the hourly values rather than the time at which they were obtained.
HourlyValues.HVTime6 Investigators were requested to document hourly values every 2 hours (12 times per day) for all patients receiving ICP monitoring. The timeperiods were pre-specified (02:00-24:00); however, investigators may have entered values at different times and have then entered the time of obtaining hourly values; a possible confusion may exist if investigators entered the time of documenting the hourly values rather than the time at which they were obtained.
HourlyValues.HVTime8 Investigators were requested to document hourly values every 2 hours (12 times per day) for all patients receiving ICP monitoring. The timeperiods were pre-specified (02:00-24:00); however, investigators may have entered values at different times and have then entered the time of obtaining hourly values; a possible confusion may exist if investigators entered the time of documenting the hourly values rather than the time at which they were obtained.
Imaging.AcquisitionDate
Imaging.AcquisitionTime
Imaging.AnyIntracranTraumaticAbnormality This variable was assessed by a central review panel, according the TBI-Common Data Elements. This variable indicates whether any of the 12 following CDEs is present (Mass lesion, ExtraaxialHematoma, EpiduralHematoma, SubduralHematomaAcute, SubduralHematomaSubacuteChronic, SubduralCollectionMixedDensity, Contusion, TAI, traumaticSubarachnoidHemorrhage, IntraventricularHemorrhage, MidlineShift or CisternalCompression.
Imaging.BvalURL
Imaging.BvecURL
Imaging.CisternalCompression This variable was assessed by a central review panel, according the TBI-Common Data Elements. This variable indicates whether there is compression of one or more the basal cisterns (i.e. suprasellar, quadrigeminal, prepontine, ambient, cisterna magna). More descriptive information (location, compression vs. absence) can be found in the JSON files.
Imaging.Contusion This variable was assessed by a central review panel, according the TBI-Common Data Elements. This variable indicates whether one or more contusions are present. More descriptive information (location, volume, number) and advanced information (e.g. hemorrhagic, non-hemorrhagic, intracerebral hemorrhage, etc.) can be found in the JSON files. Volume was estimated using the AxBxC/2 method. Edema was included in the measurements.
Imaging.CRFCTAngulation
Imaging.CRFCTManuf
Imaging.CRFCTMidlineShift
Imaging.CRFCTMidlineShiftMeasure
Imaging.CRFCTMRIDate
Imaging.CRFCTMRITime
Imaging.CRFCTReason
Imaging.CRFCTScannerType
Imaging.CRFCTType
Imaging.CRFForm
Imaging.CRFIcometrixImageId This variable combines data from CTMRI.IcometrixImageId and FollowUp.IcometrixImageId. Identifier generated for an imaging experiment when images are uploaded from site.
Imaging.CRFIcometrixPassedQA
Imaging.CRFIcometrixQADateTime
Imaging.CRFIcometrixUploadDateTime
Imaging.CRFInitialDataIcometrix
Imaging.CRFMRIManuf
Imaging.CRFMRIReason
Imaging.CRFMRIReasonOther
Imaging.CRFMRIResultPreExistAbnorm
Imaging.CRFMRIResultTraumaticAbnorm
Imaging.CRFMRIScannerStrength
Imaging.CRFMRISequences
Imaging.CRFMRITraumAbnormASDH
Imaging.CRFMRITraumAbnormContusion
Imaging.CRFMRITraumAbnormDAI
Imaging.CRFMRITraumAbnormDAILesionLocBrainstem
Imaging.CRFMRITraumAbnormDAILesionLocCorpusCallosum
Imaging.CRFMRITraumAbnormDAILesionLocDiffuseWhiteMatter
Imaging.CRFMRITraumAbnormDAINumLesions
Imaging.CRFMRITraumAbnormEDH
Imaging.CRFMRIType
Imaging.CRFTimePoint Imaging.CRFTimepoint = CTMRI.Timepoint + FollowUp.Timepoint Imaging related data from CTMRI table and Followup is combined under Imaging table so that all data is available in a single place. We only combine the ones with a valid IcometrixImageId
Imaging.DicomHeaderURL DICOM header can add more information to the Nifti image files. The DICOM header is the meta-data part of a DICOM file and is organized as a constant and standardized series of tags. This variable is a URL towards the header file.
Imaging.EpiduralHematoma This variable was assessed by a central review panel, according the TBI-Common Data Elements. This variable indicates whether an epidural hematoma or multiple epidural hematomas are present. More descriptive information (location, volume, number) and advanced information (e.g. arterial versus venous) can be found in the JSON files. Note: Volume was estimated using the AxBxC/2 method. In the JSON files, "descriptive_volume" is the estimated volume of the lesion and can be used for analysis, "descriptive_length", "descriptive_width", "descriptive_max_thickness" are measurements that should not be used in any analysis.
Imaging.ExperimentDate
Imaging.ExperimentDateTime S: Date and time at which one images are acquired. B: An experiment is an entire session of images acquisition with multiple scans. Source of the date is the dicom tag '(0008,0020) Study Date'. Source of the time is the dicom tag '(0008,0030), Study Time' A: Date and time of the experiment in iso-8601 format. (YYYY-MM-DD hh:mm:ss) R: If Study Time tag was empty, we used '(0008,0031), Series Time'. If Study and Series Time was empty, we used '(0008,0032), Acquisition Time'. If time not available at all, time is replaced with 00:00:00. If date is anterior to 01-01-1970, the date has not been provided by the center. (not available in Study Date dicom header tag)
Imaging.ExperimentId S: Experiment id which is generated by the imaging repository (XNAT). B: Is a unique identifier. XNAT is the imaging platform used to collect the data. A: Format of this identifier looks like CTBI_E00000. R: ExperimentId is equal to all the scans within the same experiment: projects/PROJECT_ID/subjects/SUBJECT_ID/experiments/EXPT_ID/scans/SCAN_ID/files/file1.img
Imaging.ExperimentLabel S: Experiment label created by the imaging repository. B: Usually looks like: "GUPI_CTx" or "GUPI_MRx" with x specifying the rank of the upload. This label is not a unique identifier. A: Label of the experiment. R: Users are allowed to edit. Label is only unique within one center.
Imaging.ExperimentTime
Imaging.ExtraaxialHematoma This variable was assessed by a central review panel, according the TBI-Common Data Elements. This variable indicates whether an extra-axial hematoma or multiple extra-axial hematomas are present. This term was mostly used for bleedings that were difficult to classify or for bleedings that were evacuated (i.e. after craniectomy). More descriptive information (location, volume, number) and advanced information (e.g. arterial versus venous) can be found in the JSON files. Note: Volume was estimated using the AxBxC/2 method. In the JSON files, "descriptive_volume" is the estimated volume of the lesion and can be used for analysis, "descriptive_length", "descriptive_width", "descriptive_max_thickness" are measurements that should not be used in any analysis.
Imaging.FisherClassification S: A CT grading scale for traumatic Subarachnoid Hemorrhage B: Useful in predicting the occurrence and severity of cerebral vasospasm. Ranges from 1-4 (No tSAH, no IVH (1), no IVH, trace or moderate tSAH (can be in multiple locations) (2), No IVH, full tSAH (3), IVH (4) R: Only available for CT scans. For each patient, the FisherClassification can be found in the Imaging.LesionData variable. For CENTER-TBI, only the older version of Fisher was scored, not the newer "modified" version.
Imaging.Frames B: Scan are acquired in dicom format. A: Number of dicom files that compose the scan.
Imaging.GreenCTGrade A CT grading scale for traumatic Subarachnoid Hemorrhage (tSAH). Useful for outcome prediction. Ranges from 1-4, with a subdivision of 3 into "31", "32" and 4 into "41" and "42". (thin tSAH (1), thick tSAH (2), thin tSAH with mass lesion and no MLS (31), thin tSAH with mass lesion and MLS (32), thick tSAH with mass lesion and no MLS (41), thick tSAH with mass lesion and MLS (42). Only available for CT scans. For each patient, the GreenCTgrade can be found in the Imaging.LesionData variable. Could only be filled out when tSAH was present.
Imaging.HelsinkiCTScore S: A general CT grading scale B: Useful for outcome prediction. Ranges from -3 to 14. Scoring is done as follows: subdural (+2), intracerebral hematoma (+2), epidural hematoma (-3), mass lesion size >25 cc (+2), IVH (+3), compressed cisterns (+1), obliterated cisterns (+5) R: Only available for CT scans. For each patient, the HelsinkiCTscore can be found in the Imaging.LesionData variable. Empty values for the HelsinkiCTscore stand for a normal CT scan! A score of 0 does not necessarily mean the patient had a normal CT. (e.g. epidural hematoma -3, + IVH = 3 = 0).
Imaging.IntraventricularHemorrhage This variable was assessed by a central review panel, according the TBI-Common Data Elements. This variable indicates whether intraventricular blood is present. More descriptive information (location) can be found in the JSON files.
Imaging.LesionData This variable contains ALL lesion information as assessed by central review. There are 23 CDEs that have been evaluated for each patient and 6 classifications that have been filled out. For 13 CDEs and all 6 classifications separate variables have been made available. (see "imaging." variables: SkullFracture, Mass lesion, ExtraaxialHematoma, EpiduralHematoma, SubduralHematomaAcute, SubduralHematomaSubacuteChronic, SubduralCollectionMixedDensity, Contusion, TAI, traumaticSubarachnoidHemorrhage, IntraventricularHemorrhage, MidlineShift, CisternalCompression. A derived variable was also created with AnyIntracranTraumaticAbnormality). These 13 CDEs only contain basic information (i.e. lesion is present, absent, indeterminate, uinterpretable, not interpreted).
Imaging.Manufacturer S: Imaging scanner manufacturer. R: Tag (0008,0070) from dicom header available in Imaging.DicomHeaderURL
Imaging.MarshallCTClassification A general CT grading scale. Useful for outcome prediction. Ranges from 1 to 6 in our dataset. (No visible pathology on CT (1), Cisterns present, MLS < 5 mm (2), Cisterns compressed or absent, MLS < 5 mm (3), MLS > 5 mm, no mass lesion > 25 cc (4), Evacuated mass lesion (5), Non-evacuated mass lesion (6)) Only available for CT scans. For each patient, the MarshallCTClassification can be found in a Imaging.LesionData variable. For the Marshall CT classification the admission scan was scored. (which is not necessarily the "worst").
Imaging.MassLesion This variable was assessed by a central review panel, according the TBI-Common Data Elements. This variable indicates whether a mass lesion is present. "Mass Lesion" in this case was defined as a total brain lesion volume > 25 cc. Note that this can mean that there is at least one large lesion or multiple co-existing lesions (contusions, subdural hematomas, etc.) that add up to > 25 cc. More information can be found in the JSON files.
Imaging.MidlineShift This variable was assessed by a central review panel, according the TBI-Common Data Elements. This variable indicates whether a midline shift of > 5 mm is present. More descriptive information (direction) can be found in the JSON files.
Imaging.MorrisMarshallClassification S: A CT grading scale for traumatic Subarachnoid Hemorrhage (tSAH) B: Useful for outcome prediction. Ranges from 0-4. (no tSAH (0), trace or moderate tSAH in one location (basal, cortical or tentorial) (1), one location full, or 2 not full (2), two locations full (3), 3 locations or more (4)) R: Only available for CT scans. For each patient, the MorrisMarshallClassification can be found in a Imaging.LesionData variable.
Imaging.NiftiURL S: Nifti files are converted from original dicom files. B: Nifti is an imaging format.(Neuroimaging Informatics Technology Initiative file format) A: This variable is an URL towards the generated nifti file. R: Open source tool to convert dicom to nifti https://github.com/icometrix/dicom2nifti
Imaging.QCResultsURL S: A json file containing MR quality measures. B: All different quality measures that have been applied are being collected in one json file. The comprises at least a protocol check, snr, cnr, head coverage, GM/WM, FA/MD, tensor residuals, ... A: Url to the .json file
Imaging.ReportStatus S: Visual inspection remark B: All MR images have been visually inspected and labeled as approved, rejected or approved with remark. The remark can be found in Imaging.ReportStatusComments R: Imaging.QCResultsURL is being used during this visual inspection. This is the prefered status of the quality of the images.
Imaging.ReportStatusComments S: Comment on the report status B: All MR images have been visually inspected and labeled as approved, rejected or approved with remark. This variable contains the motivation if the status is rejected or approved with remark.
Imaging.RotterdamCTScore S: A general CT grading scale B: Useful for outcome prediction. Ranges from 1 to 6 in our dataset. Scoring was as follows: IVH or tSAH (+1), Epidural Mass not present (+1), MLS > 5 mm (+1), cisterns compressed (+1), cisterns absent (+1), SUM SCORE = +1 R: Only available for CT scans. For each patient, the RotterdamCTscore can be found in the Imaging.LesionData variable.
Imaging.ScanDetection S: Triaging variable for the usablity of a CT scan B: Since all clinical CT scans (head, neck, spine, ...) are uploaded, it is not always clear which scans are usable an which not. In order to know what scans are usable, a variable is defined. This variable gives as an output: UNUSABLE SCANS / USABLE SCANS / DOUBTFULL. R: This triaging is done by computer algorithms and is not 100% water tight.
Imaging.ScanLabel S: Scan label is a specific identifier for a scan. A: Scan label contains 3 parts: Imaging.ExperimentID Imaging.ExperimentLabel (0020,0011) Series Number (from dicom header) Format: Imaging.ExperimentID_Imaging.ExperimentLabel_SeriesNumber "
Imaging.Scanner Imaging scanner This information is available from the Imaging.DicomHeaderURL
Imaging.ScanNotes S: Free text remarks from dcm2nii conversion B: This free text variable is used for internal purpose A: R: opensource dcm2nii converter available https://github.com/icometrix/dicom2nifti
Imaging.ScanQuality S: This variable is specified by the one who uploaded the images to the imaging repository B: Possible values are usable, questionable, unusable A: Quality of the scan R: Might be very arbitrary and therefor preferable use Imaging.QCResultsURL data and Imaging.ReportStatus as quality reference.
Imaging.ScanType S: MR Mapping for series description B: Since all centers use different series description, a mapping for T2, T1, FLAIR, T2*, DTI and rs-fMRI is provided. R: For CT, ScanType and Series Description should be the same.
Imaging.SeriesDescription S: Scan Series description retrieved from DICOM header A: Serie Name Given by the image acquisition center. R: DICOM Tag (0008,103E) Series Description
Imaging.SkullFracture This variable was assessed by a central review panel, according the TBI-Common Data Elements. This variable indicates whether a skull fracture or multiple skull fractures are present. More descriptive information (location, number) and advanced information (morphology: e.g. depressed, compound, etc.) can be found in the JSON files.
Imaging.SnapshotURL S: Mid-slice snapshot from three planes: axial, sagittal and coronal. B: In order to have a quick view on the data, a snapshot of the mid-slice in 3 planes is provided. A: Url to .png screenshot of generated nifti images. R: Screenshot are defaced.
Imaging.SubduralCollectionMixedDensity This variable was assessed by a central review panel, according the TBI-Common Data Elements. This variable indicates whether one or multiple subdural collections/mixed density hematomas are present. More descriptive information (location, volume, number) and advanced information (e.g. isodensity, hypodensity, acute on chronic, chronic recurrent etc.) can be found in the JSON files. Volume was estimated using the AxBxC/2 method. Note: cfr. epidural and subdural hematoms regarding volumes. Note: In the JSON files length, width and depth of lesions can not be used as metrics in any analysis! Only "descriptive volume" is a valid metric (in cc)
Imaging.SubduralHematomaAcute This variable was assessed by a central review panel, according the TBI-Common Data Elements. This variable indicates whether an acute subdural hematoma or multiple acute subdural hematomas are present. More descriptive information (location, volume, number) and advanced information (homogeneous versus heterogeneous) can be found in the JSON files.Volume was estimated using the AxBxC/2 method, however, small traces of acute subdural blood on the tentorium or interhemispheric were not measured. Note: cfr. epidural: only "descriptive_volume" can be used for analysis. Note: In the JSON files length, width and depth of lesions can not be used as metrics in any analysis! Only "descriptive volume" is a valid metric (in cc)
Imaging.SubduralHematomaSubacuteChronic This variable was assessed by a central review panel, according the TBI-Common Data Elements. This variable indicates whether one or multiple subacute/chronic subdural hematoma(s) are present. More descriptive information (location, volume, number) can be found in the JSON files.Note: Volume was estimated using the AxBxC/2 method. Note: this variable is best considered together with the "SubduralCollectionMixedDensity" variable, as the central reviewer did not have information to time of injury. Many subacute/chronic subdurals were therefore categorised as "mixed density". Note: cfr. epidural and acute subdural hematoma regarding volumes. Note: In the JSON files length, width and depth of lesions can not be used as metrics in any analysis! Only "descriptive volume" is a valid metric (in cc)
Imaging.SubjectGroup S: Subject stratum B: Possible options are: ER, ADMISSION, ICU
Imaging.TAI This variable was assessed by a central review panel, according the TBI-Common Data Elements. This variable indicates whether axonal injury is present. More descriptive information (location, TAI versus DAI) can be found in the JSON files. Note: be aware of the modality you are interested in (i.e. CT or MRI).
Imaging.ThumbnailURL S: Screenshot are automatically generated. B: Thumbnails are reduced-size versions of pictures. A: Url to .png screenshot of generated nifti images. R: You can find higher resolution image at the URL provided by Imaging.SnaphshotURL. Screenshot are defaced.
Imaging.Timepoint S: Timepoint of the scan acquisition B: For CT scans, possible options are: CT Early, CT Followup, CT Post-op For MR scans, possible options are: MR Early, MR 2 weeks, MR 3 months, MR 6 months, MR 12 months, MR 24 months A: Timepoint of the scan acquisition. R: Date and Time of the experiment is available in Imaging.ExperimentDateTime In order to have the intitial CT reports, download this variable in Neurobot, together with Subject.GUPI, Imaging.ExperimentId and your variables of interest. See steps Imaging.ExperimentId variable.
Imaging.TraumaticSubarachnoidHemorrhage This variable was assessed by a central review panel, according the TBI-Common Data Elements. This variable indicates whether traumatic subarachnoid blood is present. More descriptive information (location and amount (e.g. trace, moderate, severe)) can be found in the JSON files. * Location can be: cortical, basal, interhemispheric or tentorial.
Imaging.UploadDateTime S: Date and time of upload of the scans to the imaging repository R: UploadDateTime can only be after ExperimentDateTime.
Imaging.WindowDetectionComment Available in case Imaging.WindowDetectionQuality = Window Uncertainty. Imaging.WindowDetection specify if the images are Bone Window, Brain Window or if there is Window Uncertainty. Only available for CT scans.
Imaging.WindowDetectionQuality S: Automated Detection for bone versus brain. B: Possible options: Bone Window, Brain Window, Window Uncertainty R: Only available for CT scans. No brain window scans should be classified as bone window.
Imaging.XsiType S: Type of imaging (CT/MR) A: Assess if the scan is CT or MR R: Possible values 'xnat:mrSessionData' and 'xnat:ctSessionData'
InjuryHx.AbdomenPelvicContentsAIS 0 == 0
1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
InjuryHx.AbdomenPelvicContentsDesc 1 == Spleen rupture
2 == Liver rupture
3 == Perforating abdominal injury
4 == Kidney contusion
5 == Retroperitoneal hematoma
99 == Other
InjuryHx.AbdomenPelvicContentsISS
InjuryHx.ACEFocalNeuroDeficit 0 == No
1 == Yes
88 == Unknown
InjuryHx.ACEFocalNeuroDeficitDysphasia 0 == No
1 == Yes
88 == Unknown
InjuryHx.ACEFocalNeuroDeficitOther
InjuryHx.ACEFocalNeuroDeficitOtherTxt
InjuryHx.ACEFocalNeuroDeficitParesis 0 == No
1 == Yes
88 == Unknown
InjuryHx.ACEOverallRating 1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
InjuryHx.ACEOverallRatingUnknown
InjuryHx.ACERatedBy 1 == Proxy
2 == Subject
3 == Both proxy and subject
4 == Not done
InjuryHx.AlcPriorUseInd 0 == No
1 == Yes
88 == Unknown
InjuryHx.AlcUseDur Only applicable if use marked "yes"
InjuryHx.AlcUseLstMoDaysDrankNum 0 == No
1 == Yes
88 == Unknown
InjuryHx.AUDITCAlcDrnkTypclDayNumScore 1 == 1-2
2 == 3-4
3 == 5-6
4 == 7-9
5 == 10 or more
88 == Unknown
InjuryHx.AUDITCDrnkContainAlcFreqScore 0 == Never
1 == Monthly or less
2 == 2-4 times a month
3 == 2-3 times a week
4 == 4 or more times a week
88 == Unknown
Detailed questions on the use of alcohol are derived from the first 3 questions of the "AUDIT" questionnaire,a screening tool developed by the World Health Organization (WHO) to assess alcohol consumption, drinking behaviors, and alcohol-related problems. The same questions are asked post-injury during full follow-up assessments (including cognitive testing.)
InjuryHx.AUDITCMoreThan6AlcDrnkFreqScore 0 == Never
1 == Monthly or less (incorrect please correct)
2 == 2-4 times a month (incorrect please correct)
3 == 2-3 times a week (incorrect please correct)
4 == 4 or more times a week (incorrect please correct)
5 == Less than monthly
6 == Monthly
7 == Weekly
8 == Daily or almost daily
88 == Unknown
InjuryHx.BaselineGCSMostReliableAssessmentCondition 0 == No sedation/paralysis
1 == Under sedation
3 == After stopping sedation
4 == After pharmacological reversal
InjuryHx.BaselineGCSMostReliableAssessmentTime 1 == Admission
2 == Post-stabilization
3 == First hospital
4 == Scene of accident
5 == Other
InjuryHx.BaselineGCSMostReliableMotorScore Most reliable baseline Motor score of the GCS as given by sites for use in prognostic models.
InjuryHx.BaselineGOS6MoDateOfPrognosticEstimate
InjuryHx.BaselineGOS6MoExpectedDeathRisk
InjuryHx.BaselineGOS6MoExpectedOutcome GR == GR - Good Recovery
MD == MD - Moderate Disability
SD == SD - Severe Disability
V == V - Vegetative State
D == D - Death
Documents expected outcome at time of discharge from ER (home or to ward/ICU)
InjuryHx.BaselineGOS6MoUnfavourableOutcomeRisk
InjuryHx.BaselinePhysEstOf6MoOutcomePhysicianQual 1 == Resident
2 == Junior staff (< 5 years)
3 == Senior staff (>= 5 years)
4 == Head of department
InjuryHx.BaselinePhysEstOf6MoOutcomePhysicianType 1 == ER Physician
2 == Intensive Care
3 == Neurology
4 == Neurosurgery
5 == Traumatology
88 == Unknown
InjuryHx.BestOfAbdomenPelvicLumbarISS AbdomenPelvicLumbar region (Highest AIS of the region)^2 compare AbdomenPelvicContentsAIS, LumbarSpineAIS. This score is taken forward for ISS calculation
InjuryHx.BestOfChestSpineISS (highest AIS of the region)^2 Compare ThoraxChestAIS, ThoracicSpineAIS and select the highest for ISS calculation
InjuryHx.BestOfExternaISS External region (ExternaAIS)^2 select the highest external AIS severity code for ISS calculation.
InjuryHx.BestOfExtremitiesISS Extremities region (Highest AIS of the region)^2 compare UpperExtremitiesAIS, LowerExtremitiesAIS, PelvicGirdleAIS select the highest for ISS calculation
InjuryHx.BestOfFaceISS Face region (FaceAIS)^2 select the highest facial injury for ISS calculation
InjuryHx.BestOfHeadBrainCervicalISS HeadBrainCervical region (Highest AIS of the region)^2 Compare HeadNeckAIS, InjuryHx.BrainInjuryAIS, CervicalSpineAIS select the highest scoring injury in any of these 3 areas for ISS calculation
InjuryHx.BrainInjuryAIS 0 == 0
1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
InjuryHx.BrainInjuryDesc 1 == Concussion
2 == Contusions
3 == EDH
4 == Diffuse Injury
5 == ASDH
99 == Other
Injury description is coded by drop-down menus for each body region
InjuryHx.CannabisCurrentUse 0 == No
1 == Yes
88 == Unknown
InjuryHx.CannabisPriorUse 0 == No
1 == Yes
88 == Unknown
InjuryHx.CannabisPriorUseDuration Only applicable if use marked "yes"
InjuryHx.CervicalSpineAIS 0 == 0
1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
InjuryHx.CervicalSpineDesc 1 == Fracture
2 == Dislocation
99 == Other
InjuryHx.DispER 1 == Discharge home
2 == Discharge other facility
3 == Hospital admission--Ward
4 == Hospital admission--Intermediate/high care unit
5 == Hospital admission--ICU
6 == Hospital admission--OR for immediate surgical procedure
7 == Death
8 == Hospital admission--Other (e.g. observation unit)
88 == Unknown
InjuryHx.DrgSubIllctCurntUseInd 0 == No
1 == Yes
88 == Unknown
InjuryHx.DrgSubIllctUseCatOther
InjuryHx.DrgSubIllctUseDur Only applicable if use marked "yes"
InjuryHx.DrgSubPriorIllctUseInd 0 == No
1 == Yes
88 == Unknown
InjuryHx.DrugIllicitCurrentUseOther
InjuryHx.EDAirway 1 == No specific treatment
2 == Supplemental oxygen (via nasal tube or mask)
3 == Adjunctive airway (eg. Mayo tube)
4 == Temporary support with bag, valve, mask (eg.ambubag)
5 == Intubation
6 == Mechanical ventilation
88 == Unknown
Records Tx performed in the ER/on admission. Pre-hospital inteventions are documented at:InjuryHx.PresEmergencyCare
InjuryHx.EDArrDBP
InjuryHx.EDArrHR
InjuryHx.EDArrivalAirway 1 == Clear
2 == Obstructed
3 == Adjunctive Airway
4 == Intubated
88 == Unknown
The ABC status on arrival documents the status of Airway, Breathing and Circulation upon arrival to Study Hospital (ER); In addition, administration of supplemental oxygen and spinal immobilization is documented.
InjuryHx.EDArrivalArtpCO2kPa
InjuryHx.EDArrivalArtpCO2mmhg
InjuryHx.EDArrivalArtpCO2unit 1 == kPa
2 == mmHg
InjuryHx.EDArrivalArtpCO2Unknown
InjuryHx.EDArrivalArtpO2kPa
InjuryHx.EDArrivalArtpO2mmhg
InjuryHx.EDArrivalArtpO2unit 1 == kPa
2 == mmHg
InjuryHx.EDArrivalArtpO2Unknown
InjuryHx.EDArrivalBaseExcess
InjuryHx.EDArrivalBaseExcessUnit 1 == mEq/l
99 == Other
InjuryHx.EDArrivalBaseExcessUnitSpecify
InjuryHx.EDArrivalBaseExcessUnknown
InjuryHx.EDArrivalBloodGasDone 0 == No
1 == Yes
Arterial blood gas analysis is not required for all subjects. Performed on clinical indication; will generally be restricted to subjects with more severe injuries
InjuryHx.EDArrivalBloodPressureUnknown 88 == Unknown
InjuryHx.EDArrivalBMI BMI using height in inches (EDArrivalHeightInches) and weight in pounds (EDArrivalBodyWeightLbs) BMI=((weight/(height*height)) * 704.5469
InjuryHx.EDArrivalBMIKgCm BMI using height in cm (EDArrivalHeightCm) and weight (EDArrivalBodyWeightKg) BMI= (Weight/(Height*Height))) * 10000
InjuryHx.EDArrivalBodyWeightKg
InjuryHx.EDArrivalBodyWeightLbs
InjuryHx.EDArrivalBodyWeightMeasured 1 == Estimated
2 == Self reported
3 == Measured
4 == Proxy reported
88 == Unknown
Provides an indication of accuracy of reported weight
InjuryHx.EDArrivalBodyWeightUnit 1 == kg
2 == lbs
InjuryHx.EDArrivalBreathing 1 == Spontaneous, adequate
2 == Spontaneous, insufficient
3 == Manual support with bag, valve, mask
4 == Mechanical ventilation
88 == Unknown
InjuryHx.EDArrivalCirculation 0 == No specific therapy
1 == IV Fluids
2 == Vasopressors
3 == CPR
88 == Unknown
InjuryHx.EDArrivalFiO2 Information on FiO2 (Fraction of Inspired oxygen) at time of arterial blood gas sampling is requested in order to be able to calculate PaO2/FiO2 as measure of severity of hypoxaemia; dependent on altitude; at sea-level, normal values are > 500 mmHg
InjuryHx.EDArrivalFiO2Unknown
InjuryHx.EDArrivalHeartRateUnknown
InjuryHx.EDArrivalHeightCm
InjuryHx.EDArrivalHeightInches
InjuryHx.EDArrivalHeightMeasured 1 == Estimated
2 == Self reported
3 == Measured
4 == Proxy reported
88 == Unknown
Provides an indication of accuracy of reported height
InjuryHx.EDArrivalHeightUnit 1 == cm
2 == inch
InjuryHx.EDArrivalLactate
InjuryHx.EDArrivalLactateUnit 1 == mEq/l
99 == Other
InjuryHx.EDArrivalLactateUnitSpecify
InjuryHx.EDArrivalLactateUnknown
InjuryHx.EDArrivalOxygenSatUnknown
InjuryHx.EDArrivalpH
InjuryHx.EDArrivalpHUnknown
InjuryHx.EDArrivalRespRateUnknown 1 == Spontaneous
2 == Ventilated
88 == Unknown
InjuryHx.EDArrivalSpinalImmob 0 == No
1 == Yes
88 == Unknown
InjuryHx.EDArrivalSupplementalOxygen 0 == No
1 == Yes
88 == Unknown
InjuryHx.EDArrivalTemperatureUnknown
InjuryHx.EDArrPupilLftEyeMeasr 1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
7 == 7
8 == 8
9 == 9
10 == 10
InjuryHx.EDArrPupilLftEyeMeasrUnkUnt 66 == Untestable
88 == Unknown
InjuryHx.EDArrPupilReactivityLghtLftEyeReslt 1 == + (Brisk)
2 == + (Sluggish)
3 == - (Negative)
InjuryHx.EDArrPupilReactivityLghtRtEyeReslt 1 == + (Brisk)
2 == + (Sluggish)
3 == - (Negative)
InjuryHx.EDArrPupilRtEyeMeasr 1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
7 == 7
8 == 8
9 == 9
10 == 10
InjuryHx.EDArrPupilRtEyeMeasrUnkUnt 66 == Untestable
88 == Unknown
InjuryHx.EDArrPupilSymmetry 1 == Equal
2 == Unequal R>L
3 == Unequal L>R
66 == Untestable
88 == Unknown
InjuryHx.EDArrRespRate
InjuryHx.EDArrSBP The vital signs reported here are intended to document the first values obtained on presentation to study hospital
InjuryHx.EDArrSpO2
InjuryHx.EDArrTempCelsius
InjuryHx.EDArrTempFahrenheit
InjuryHx.EDArrTempUnit 1 == C
2 == F
InjuryHx.EDBloodGasConditions 1 == Pre-intubation, room air
2 == Pre-intubation, +O2
3 == Post-intubation, not ventilated
4 == Post-intubation, ventilated
InjuryHx.EDBloodGasDate
InjuryHx.EDBloodGasTime
InjuryHx.EDBloodTrans 0 == No
1 == Yes
88 == Unknown
InjuryHx.EDCircCPR
InjuryHx.EDCircIV
InjuryHx.EDCircNone Records Tx performed in the ER/on admission. Pre-hospital inteventions are documented at: InjuryHx.PresCirculationTreatmentNone
InjuryHx.EDCircUnknown
InjuryHx.EDCircVaso
InjuryHx.EDCoagulopathyType1 1 == Packed red blood cell concentrates (pRBCs)
2 == Fresh whole blood
3 == Fresh frozen plasma (FFP)
4 == Freeze dried plasma / lypholized plasma
5 == Platelet concentrates
6 == PCC (prothrombin complex concentrates)
7 == Fibrinogen concentrate
8 == Albumin
9 == Recombinant factor FVIIa
10 == Tranexamic acid (TXA)
11 == Cryoprecipitate
12 == Desmopression (DDAVP)
13 == Factor XIII
14 == Calcium
15 == Vitamin K (Konakion)
InjuryHx.EDCoagulopathyType2 1 == Packed red blood cell concentrates (pRBCs)
2 == Fresh whole blood
3 == Fresh frozen plasma (FFP)
4 == Freeze dried plasma / lypholized plasma
5 == Platelet concentrates
6 == PCC (prothrombin complex concentrates)
7 == Fibrinogen concentrate
8 == Albumin
9 == Recombinant factor FVIIa
10 == Tranexamic acid (TXA)
11 == Cryoprecipitate
12 == Desmopression (DDAVP)
13 == Factor XIII
14 == Calcium
15 == Vitamin K (Konakion)
InjuryHx.EDCoagulopathyType3 1 == Packed red blood cell concentrates (pRBCs)
2 == Fresh whole blood
3 == Fresh frozen plasma (FFP)
4 == Freeze dried plasma / lypholized plasma
5 == Platelet concentrates
6 == PCC (prothrombin complex concentrates)
7 == Fibrinogen concentrate
8 == Albumin
9 == Recombinant factor FVIIa
10 == Tranexamic acid (TXA)
11 == Cryoprecipitate
12 == Desmopression (DDAVP)
13 == Factor XIII
14 == Calcium
15 == Vitamin K (Konakion)
InjuryHx.EDCoagulopathyType4 1 == Packed red blood cell concentrates (pRBCs)
2 == Fresh whole blood
3 == Fresh frozen plasma (FFP)
4 == Freeze dried plasma / lypholized plasma
5 == Platelet concentrates
6 == PCC (prothrombin complex concentrates)
7 == Fibrinogen concentrate
8 == Albumin
9 == Recombinant factor FVIIa
10 == Tranexamic acid (TXA)
11 == Cryoprecipitate
12 == Desmopression (DDAVP)
13 == Factor XIII
14 == Calcium
15 == Vitamin K (Konakion)
InjuryHx.EDCoagulopathyVolume1
InjuryHx.EDCoagulopathyVolume2
InjuryHx.EDCoagulopathyVolume3
InjuryHx.EDCoagulopathyVolume4
InjuryHx.EDCompEventHypothermia 0 == No
1 == Definite
2 == Suspect
88 == Unknown
Second Insults reported here relate to the pre-hospital and ER phase. Hypothermia is defined as a documented core temperature of < 35 C.
InjuryHx.EDComplEventCardArr 0 == No
1 == Yes
InjuryHx.EDComplEventHypotension 0 == No
1 == Definite
2 == Suspect
88 == Unknown
Second Insults reported here relate to the pre-hospital and ER phase. Definite hypotension is defined as a documented systolic BP < 90 mm Hg (adults); "Suspected" was scored if the patient did not have a documented blood pressure, but was reported to be in shock or have an absent brachial pulse (not related to injury of the extremity)
InjuryHx.EDComplEventHypoxia 0 == No
1 == Definite
2 == Suspect
88 == Unknown
Second Insults reported here relate to the pre-hospital and ER phase. Definite hypoxia is defined as a documented PaO2 <8 kPa (60 mm Hg) and/or SaO2<90%; "Suspected" was scored if the patient did not have documented hypoxia by PaO2 or SaO2, but there was a clinical suspicion , as evidenced by for example cyanosis, apnoea or respiratory distress
InjuryHx.EDComplEventSeizures 0 == No
1 == Partial/Focal
2 == Generalized
3 == Status epilepticus
88 == Unknown
InjuryHx.EDCorrCoagulopathy 0 == No
1 == Yes
88 == Unknown
Documents blood transfusions and treatment of coagulopathy in the acute phase at presentation.
InjuryHx.EDDischDate
InjuryHx.EDDischPupilLftEyeMeasr 1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
7 == 7
8 == 8
9 == 9
10 == 10
InjuryHx.EDDischPupilLftEyeMeasrUnkUnt 66 == Untestable
88 == Unknown
InjuryHx.EDDischPupilReactivityLghtLftEyeReslt 1 == + (Brisk)
2 == + (Sluggish)
3 == - (Negative)
InjuryHx.EDDischPupilReactivityLghtRtEyeReslt 1 == + (Brisk)
2 == + (Sluggish)
3 == - (Negative)
InjuryHx.EDDischPupilRtEyeMeasr 1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
7 == 7
8 == 8
9 == 9
10 == 10
InjuryHx.EDDischPupilRtEyeMeasrUnkUnt 66 == Untestable
88 == Unknown
InjuryHx.EDDischPupilSymmetry 1 == Equal
2 == Unequal R>L
3 == Unequal L>R
66 == Untestable
88 == Unknown
InjuryHx.EDDischTime
InjuryHx.EDICPMonitoring 0 == No
1 == Yes
88 == Unknown
Scheduled for ICP monitoring; e.g. may not accurately reflect if ICP monitoring was indeed performed
InjuryHx.EDIVAlbumin
InjuryHx.EDIVBlood
InjuryHx.EDIVColloids
InjuryHx.EDIVCrystalloids
InjuryHx.EDIVMannitol
InjuryHx.EDIVSaline
InjuryHx.EDSecondInsultsNeuroWorse 0 == No
1 == Yes
88 == Unknown
The importance of Neuroworsening was first described by Morris and Marshall. The occurrence of neuroworsening is related to poorer outcome in subjects with moderate to severe TBI. Neuroworsening is defined as 1) a decrease in GCS motor score of 2 or more points; 2) a new loss of pupillary reactivity or development of pupillary assymmetry >= 2mm; 3) deterioration in neurological or CT status sufficient to warrant immediate medical or surgical intervention
InjuryHx.EDSecondInsultsNeuroWorseYes 1 == Decrease in motor score >= 2 points
2 == Development of pupillary abnormalities
3 == Other neurological and/or CT deterioration
This variable provides a specification of the type of neuroworsening if it occurs.
InjuryHx.EDSecondInsultsPreAdmisCourse 0 == Deterioration
1 == Stable
2 == Improving
88 == Unknown
The pre-admission course should only be considered an intracranial second insult in case of Deterioration. The nature of deterioration will in most cases be further detailed under the variable "Neuroworsening".
InjuryHx.EDSpinalImmob 0 == No
1 == Yes
88 == Unknown
Records Tx performed in the ER/on admission
InjuryHx.EmergSurgInterventionsExtraCran 0 == No
1 == Yes
88 == Unknown
Documents emergency extracranial surgery performed in study hospital. Procedures performed in "first" hospital (in case of secondary referral) are documented at: InjuryHx.PresERextracranialSurg
InjuryHx.EmergSurgInterventionsExtraCranYes 1 == Damage control thoracotomy
2 == Damage control laparotomy
3 == Extraperitoneal pelvic packing
4 == External fixation limb
5 == Cranio-maxillo-facial reconstruction
99 == Other
InjuryHx.EmergSurgInterventionsExtraCranYesOther
InjuryHx.EmergSurgInterventionsIntraCran 0 == No
1 == Yes
88 == Unknown
Documents emergency intracranial surgery performed in study hospital. Procedures performed in "first" hospital (in case of secondary referral) are documented at: InjuryHx.PresERIntracranialSurg
InjuryHx.EmergSurgInterventionsIntraCranYes 1 == Craniotomy for haematoma/contusion
2 == Decompressive Craniectomy
3 == Depressed skull fracture
99 == Other intracranial procedure
InjuryHx.EmerSurgIntraCranSurviveNoSurg These 2 variables aim to capture information on the surgeon's expectations, eg if the surgeon considers a realistic expectation of benefit, or performs the surgery as a "last resort" in a likely hopeless case.
InjuryHx.EmerSurgIntraCranSurviveYesSurg These 2 variables aim to capture information on the surgeon's expectations, eg if the surgeon considers a realistic expectation of benefit, or performs the surgery as a "last resort" in a likely hopeless case.
InjuryHx.ERDestICDCodes1
InjuryHx.ERDestICDCodes10
InjuryHx.ERDestICDCodes11
InjuryHx.ERDestICDCodes12
InjuryHx.ERDestICDCodes13
InjuryHx.ERDestICDCodes14
InjuryHx.ERDestICDCodes15
InjuryHx.ERDestICDCodes16
InjuryHx.ERDestICDCodes2
InjuryHx.ERDestICDCodes3
InjuryHx.ERDestICDCodes4
InjuryHx.ERDestICDCodes5
InjuryHx.ERDestICDCodes6
InjuryHx.ERDestICDCodes7
InjuryHx.ERDestICDCodes8
InjuryHx.ERDestICDCodes9
InjuryHx.ERDestICDCodesVersion 9 == ICD-9
10 == ICD-10
Intent is to document ICD codes as reported by hospital administration. Up to 16 diagnoses can be entered; only applicable to subjects discharged from ER
InjuryHx.ERDischHomeSchedApptOutpatient 0 == No
1 == Yes
88 == Unknown
InjuryHx.ERDischHomeSchedApptOutpatientDate
InjuryHx.ERDischHomeSchedApptReferToGP 0 == No
1 == Yes
88 == Unknown
InjuryHx.ERDischHomeSchedApptStudyProtoFU 0 == No
1 == Yes
88 == Unknown
InjuryHx.ERDischHomeTypeOfCarePlanned 0 == None
1 == Symptomatic treatment or/and advice for the next 24/48h
2 == Systematic follow-up visit by GP
3 == Systematic follow-up visit by specialist practitioner
4 == Oral information on TBI, its possible late consequences, and where to consult in case of difficulties
5 == Written information on TBI, its possible late consequences, and where to consult in case of difficulties
InjuryHx.ERDischMotivForDestChoice 1 == Normal CT
2 == Medical necessity
3 == Social circumstances
4 == No (ICU-) beds available
5 == Requiring specialized facilities
88 == Unknown
99 == Other
WHY Question: documents main reason for choice of destination.
InjuryHx.ERDischMotivForDestChoiceOther
InjuryHx.ExternaAIS 0 == 0
1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
InjuryHx.ExternaDesc 1 == No values yet
InjuryHx.FaceAIS 0 == 0
1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
InjuryHx.FaceDesc 1 == Maxillo-facial fracture le Fort I
2 == Maxillo-facial fracture le Fort II
3 == Maxillo-facial fracture le Fort III
4 == Orbital fracture
5 == Zygomatic arch fracture
99 == Other
InjuryHx.FirstHospAssmtCondition 0 == No sedation or paralysis
1 == Sedated
2 == Paralyzed
3 == Temporary stop of sedation/paralysis
4 == Reversal of sedation/paralysis
5 == Active reversal (pharmacologic) of sedation/paralysis
99 == Other
Describes the condition under which the GCS was assessed.
InjuryHx.GcsEDArrAssmtCond 0 == No sedation or paralysis
1 == Sedated
2 == Paralyzed
3 == Temporary stop of sedation/paralysis
4 == Reversal of sedation/paralysis
5 == Active reversal (pharmacologic) of sedation/paralysis
99 == Other
Describes the condition under which the GCS was assessed.
InjuryHx.GCSEDArrEyes O == Untestable (other)
UN == Unknown
S == Untestable (swollen)
1 == 1-None
2 == 2-To pain
3 == 3-To speech
4 == 4-Spontaneously
GCS Eye opening at arrival to ER of study hospital
InjuryHx.GCSEDArrMotor UN == Unknown
O == Untestable (Other)
P == Untestable (Deep sedation/paralyzed)
1 == 1-None
2 == 2-Abnormal extension
3 == 3-Abnormal flexion
4 == 4-Normal flexion/withdrawal
5 == 5-Localizes to pain
6 == 6-Obeys command
GCS Motor at arrival to ER of study hospital
InjuryHx.GcsEDArrNotDone 77 == Not done / Results not available Indication that GCS at arrival to Study hospital was not done.
InjuryHx.GCSEDArrScore Calculated score: GCSEDArrEyes + GCSEDArrMotor + GCSEDArrVerbal. If one or more of these is Untestable or unknown then = "No Sum"
InjuryHx.GcsEDArrScoreDate
InjuryHx.GcsEDArrScoreTime
InjuryHx.GCSEDArrVerbal UN == Unknown
O == Untestable (Other)
T == Untestable (Tracheotomy/endotracheal tube)
1 == 1-None
2 == 2-Incomprehensible sound
3 == 3-Inappropriate words
4 == 4-Confused
5 == 5-Oriented
GCS ED Verbal at arrival to ER of study hospital
InjuryHx.GcsEDDischAssmtCond 0 == No Sedation or Paralysis
1 == Sedated
2 == Paralyzed
3 == Temporary stop of sedation/paralysis
4 == Reversal of sedation/paralysis
5 == Active reversal (pharmacologic) of sedation/paralysis
99 == Other
Describes the condition under which the GCS was assessed.
InjuryHx.GCSEDDischEyes S == Untestable (swollen)
UN == Unknown
O == Untestable (other)
1 == 1-None
2 == 2-To pain
3 == 3-To speech
4 == 4-Spontaneously
InjuryHx.GCSEDDischMotor O == Untestable (Other)
UN == Unknown
P == Untestable (Deep sedation/paralyzed)
1 == 1-None
2 == 2-Abnormal extension
3 == 3-Abnormal flexion
4 == 4-Normal flexion/withdrawal
5 == 5-Localizes to pain
6 == 6-Obeys command
InjuryHx.GcsEDDischNotDone 77 == Not done / Results not available Indication that GCS at post-stabilization was not done.
InjuryHx.GCSEDDischScore Calculated score: GCSEDDischEyes + GCSEDDischMotor + GCSEDDischVerbal. If one or more of these is Untestable or unknown then = "No Sum"
InjuryHx.GcsEDDischScoreDate
InjuryHx.GcsEDDischScoreTime
InjuryHx.GCSEDDischVerbal UN == Unknown
O == Untestable (Other)
T == Untestable (Tracheotomy/endotracheal tube)
1 == 1-None
2 == 2-Incomprehensible sound
3 == 3-Inappropriate words
4 == 4-Confused
5 == 5-Oriented
InjuryHx.GCSFirstHospEyes UN == Unknown
O == Untestable (other)
S == Untestable (swollen)
1 == 1-None
2 == 2-To pain
3 == 3-To speech
4 == 4-Spontaneously
InjuryHx.GCSFirstHospMotor UN == Unknown
P == Untestable (Deep sedation/paralyzed)
O == Untestable (Other)
1 == 1-None
2 == 2-Abnormal extension
3 == 3-Abnormal flexion
4 == 4-Normal flexion/withdrawal
5 == 5-Localizes to pain
6 == 6-Obeys command
InjuryHx.GCSFirstHospNotDone 77 == Not done / Results not available Indication that GCS at First hospital was not done.
InjuryHx.GCSFirstHospPupilLftEyeMeasure
InjuryHx.GCSFirstHospPupilLftEyeMeasureUnkUnt 66 == Untestable
88 == Unknown
InjuryHx.GCSFirstHospPupilReactivityLightLftEyeReslt 1 == + (Sluggish)
2 == + (Brisk)
3 == - (Negative)
InjuryHx.GCSFirstHospPupilReactivityLightRghtEyeReslt 1 == + (Sluggish)
2 == + (Brisk)
3 == - (Negative)
InjuryHx.GCSFirstHospPupilRightEyeMeasure
InjuryHx.GCSFirstHospPupilRightEyeMeasureUnkUnt 66 == Untestable
88 == Unknown
InjuryHx.GCSFirstHospPupilSymmetry 1 == Equal
2 == Unequal R>L
3 == Unequal L>R
66 == Untestable
88 == Unknown
InjuryHx.GCSFirstHospReportedTotalScore 3 == 3
4 == 4
5 == 5
6 == 6
7 == 7
8 == 8
9 == 9
10 == 10
11 == 11
12 == 12
13 == 13
14 == 14
15 == 15
Score by investigators in case component scores not available, but GCS sum score available
InjuryHx.GCSFirstHospScore Calculated Score: GCSFirstHospEyes + GCSFirstHospMotor + GCSFirstHospVerbal. If one or more of these is Untestable or unknown then = "No Sum" Sum Score may be recorded with no components
InjuryHx.GCSFirstHospScoreDate
InjuryHx.GCSFirstHospScoreTime
InjuryHx.GCSFirstHospVerbal UN == Unknown
O == Untestable (Other)
T == Untestable (tracheotomy/endotracheal tube)
1 == 1-None
2 == 2-Incomprehensible sound
3 == 3-Inappropriate words
4 == 4-Confused
5 == 5-Oriented
InjuryHx.GCSMotorBaselineDerived This is a derived variable calculated centrally. It represents the GCS motor score for baseline risk adjustment with missing values imputed using IMPACT methodology - take Poststabilisation value and if absent work back in time towards prehospital values until non-missing value found. RECOMMENDED FOR BASELINE RISK ADJUSTMENT.
InjuryHx.GCSOtherAssmtConditions 0 == No Sedation or Paralysis
1 == Sedated
2 == Paralyzed
3 == Temporary stop of sedation/paralysis
4 == Reversal of sedation/paralysis
5 == Active reversal (pharmacologic) of sedation/paralysis
99 == Other
Describes the condition under which the GCS was assessed.
InjuryHx.GCSOtherDate
InjuryHx.GCSOtherEyes S == Untestable (swollen)
UN == Unknown
O == Untestable (other)
1 == 1-None
2 == 2-To pain
3 == 3-To speech
4 == 4-Spontaneously
InjuryHx.GCSOtherMotor UN == Unknown
O == Untestable (Other)
P == Untestable (Deep sedation/paralyzed)
1 == 1-None
2 == 2-Abnormal extension
3 == 3-Abnormal flexion
4 == 4-Normal flexion/withdrawal
5 == 5-Localizes to pain
6 == 6-Obeys command
InjuryHx.GCSOtherNotDone 77 == Not done / Results not available Indication that GCS otherl was not done.
InjuryHx.GCSOtherPupilLftEyeMeasure
InjuryHx.GCSOtherPupilLftEyeMeasureUnkUnt 66 == Untestable
88 == Unknown
InjuryHx.GCSOtherPupilReactivityLightLftEyeReslt 1 == + (Sluggish)
2 == + (Brisk)
3 == - (Negative)
InjuryHx.GCSOtherPupilRightEyeMeasure
InjuryHx.GCSOtherPupilSymmetry 1 == Equal
2 == Unequal R>L
3 == Unequal L>R
66 == Untestable
88 == Unknown
InjuryHx.GCSOtherReactivityLightRghtEyeReslt 1 == + (Sluggish)
2 == + (Brisk)
3 == - (Negative)
InjuryHx.GCSOtherRightEyeMeasureUnkUnt 66 == Untestable
88 == Unknown
InjuryHx.GCSOtherScore Calculated Score: GCSOtherEyes + GCSOtherMotor + GCSOtherVerbal. If one or more of these is Untestable or unknown then = "No Sum" Sum score may be reported when components not available
InjuryHx.GCSOtherTime
InjuryHx.GCSOtherVerbal UN == Unknown
O == Untestable (Other)
T == Untestable (tracheotomy/endotracheal tube)
1 == 1-None
2 == 2-Incomprehensible sound
3 == 3-Inappropriate words
4 == 4-Confused
5 == 5-Oriented
InjuryHx.GcsPreHospBestDate
InjuryHx.GCSPreHospBestEyes UN == Unknown
O == Untestable (Other)
S == Untestable (swollen)
1 == 1-None
2 == 2-To pain
3 == 3-To speech
4 == 4-Spontaneously
InjuryHx.GCSPreHospBestMotor UN == Unknown
O == Untestable (Other)
P == Untestable (Deep sedation/paralyzed)
1 == 1-None
2 == 2-Abnormal extension
3 == 3-Abnormal flexion
4 == 4-Normal flexion/withdrawal
5 == 5-Localizes to pain
6 == 6-Obeys command
InjuryHx.GCSPreHospBestReportedTotalScore 3 == 3
4 == 4
5 == 5
6 == 6
7 == 7
8 == 8
9 == 9
10 == 10
11 == 11
12 == 12
13 == 13
14 == 14
15 == 15
Score by investigators in case the component scores are not available, but GCS sum score available
InjuryHx.GCSPreHospBestScore Calculated Score: GCSPreHospBestEyes + GCSPreHospBestMotor + GCSPreHospBestVerbal. If one or more of these is Untestable or unknown then = "No Sum" GCS sum score may be recorded when components not available - check "InjuryHx.GCSPreHospBestReportedTotalScore"
InjuryHx.GcsPreHospBestTime
InjuryHx.GCSPreHospBestVerbal O == Untestable (Other)
UN == Unknown
T == Untestable (Tracheotomy/endotracheal tube)
1 == 1-None
2 == 2-Incomprehensible sound
3 == 3-Inappropriate words
4 == 4-Confused
5 == 5-Oriented
InjuryHx.GcsPreHospLftEyeMeasr 1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
7 == 7
8 == 8
9 == 9
InjuryHx.GcsPreHospNotDone 77 == Not Done / Results not available The initial GCS and pupillary reactivity can be scored at 4 pre-defined moments in the pre-hospital/presentation phase: 1.: scene of accident; 2: first hospital (in case of secondary referral; 3.: arrival to Er of study hospital; 4.: post-stabilization; In addition, assessment at a different time point is possible (designated as other). A derived variable captures the highest available GCS score across these time periods. Indication that GCS at Scene of accident was not done.
InjuryHx.GCSPreHospPupilLftEyeMeasureUnkUnt 66 == Untestable
88 == Unknown
Only applicable to size of pupils
InjuryHx.GCSPreHospPupilReactivityLghtLftEyeResult 1 == + (Sluggish)
2 == + (Brisk)
3 == - (Negative)
InjuryHx.GCSPreHospPupilReactivityLghtRghtEyeResult 1 == + (Sluggish)
2 == + (Brisk)
3 == - (Negative)
InjuryHx.GCSPreHospPupilRightEyeMeasureUnkUnt 66 == Untestable
88 == Unknown
InjuryHx.GCSPreHospPupilSymmetry 1 == Equal
2 == Unequal R>L
3 == Unequal L>R
66 == Untestable
88 == Unknown
InjuryHx.GcsPreHospRghtEyeMeasr 1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
7 == 7
8 == 8
9 == 9
InjuryHx.GCSScoreBaselineDerived This is a derived variable calculated centrally. It represents the total GCS (single timepoint) for baseline risk adjustment with missing values imputed using IMPACT methodology - take Poststabilisation value and if absent work back in time towards prehospital values until non-missing value found. Intubated / untestable V score treated as unknown. RECOMMENDED FOR BASELINE RISK ADJUSTMENT.
InjuryHx.HeadNeckAIS 0 == 0
1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
InjuryHx.HeadNeckDesc
InjuryHx.HighestGCSMotorDerived This is a derived variable calculated centrally. It represents the GCS motor score for baseline risk adjustment with missing values imputed using ‘highest’ value (best neurology) methodology- take best neurology of any of prehospital to Poststabilisation time points. DEPRECATED: we recommend using GCSMotorBaselineDerived for baseline risk adjustment instead (higher pseudo-R-squared in proportional odds model).
InjuryHx.HighestGCSTotalDerived This is a derived variable calculated centrally. Total GCS (single timepoint) for baseline risk adjustment with missing values imputed using ‘highest’ value (best neurology) methodology - take best neurology of any of prehospital to Poststabilisation time points. Intubated / untestable V score treated as unknown. DEPRECATED: we recommend using GCSScoreBaselineDerived for baseline risk adjustment instead (higher pseudo-R-squared in proportional odds model).
InjuryHx.HighestPupilsDerived This is a derived variable calculated centrally. Number of reactive pupils for baseline risk adjustment with missing values imputed using ‘highest’ value (best neurology) methodology- take best neurology of any of prehospital to Poststabilisation time points. Untestable pupil ignored: I.e. 1 reactive + 1 untestable = 1 reactive (this assumption applies only to a small proportion of the data). DEPRECATED: we recommend using PupilsBaselineDerived for baseline risk adjustment instead (higher pseudo-R-squared in proportional odds model).
InjuryHx.InjArea 1 == Urban (city)
2 == Rural
88 == Unknown
InjuryHx.InjCause 1 == Road traffic incident
2 == Incidental fall
3 == Other non-intentional injury
4 == Violence/assault
5 == Act of mass violence
6 == Suicide attempt
88 == Unknown
99 == Other
InjuryHx.InjCauseOther
InjuryHx.InjIndContactSportType 1 == Boxing
2 == Martial Arts
99 == Other
Only applicable for sports/recreational injuries
InjuryHx.InjIndSportTypeOther Only applicable for sports/recreational injuries
InjuryHx.InjIntention 1 == Intentional
2 == Unintentional
3 == Undetermined
InjuryHx.InjMech 1 == High velocity trauma (acceleration/deceleration)
2 == Direct impact: blow to head
3 == Direct impact: head against object
6 == Ground level fall
7 == Fall from height > 1 meter/5 stairs
99 == Other closed head injury
Applicable for closed TBI
InjuryHx.InjMechOther
InjuryHx.InjOtherPartyInvolved 77 == N/A If no other party: N/A
InjuryHx.InjOtherPartySleepingPills 0 == No
1 == Suspect
2 == Definite
88 == Unknown
InjuryHx.InjPenetratingType 1 == Gunshot wound
2 == Fragment (incl. shell/shrapnel)
99 == Other penetrating brain injury
Only applicable if penetrating brain injury
InjuryHx.InjPenetratingTypeOther
InjuryHx.InjPlace 1 == Street/highway
2 == Home/domestic
3 == Work/school
4 == Sport/Recreational
5 == Military deployment
6 == Public location (eg. bar, station, nightclub)
88 == Unknown
99 == Other
InjuryHx.InjPlaceOther
InjuryHx.InjRecSportType 1 == Rollerblading/Skateboarding/Scootering
2 == Skiing
3 == Snowboarding
4 == Hiking/Climbing
5 == Horseriding
6 == Golf
7 == Cycling
8 == Off-road vehicular sports
9 == Water sports
10 == Playground activity
88 == Unknown
99 == Other
Only applicable for sports/recreational injuries
InjuryHx.InjRecSportTypeOther Only applicable for sports/recreational injuries
InjuryHx.InjRoadAccEjectedFromVehicle 0 == No
1 == Yes
88 == Unknown
Only applicable if subject was motor vehicle occupant
InjuryHx.InjRoadAccOtherParty 1 == Motor vehicle
2 == Pedestrian
3 == Cyclist
4 == Moped/Scooter
5 == Tram/Bus
6 == Train/Metro
7 == Obstacle
10 == Motor Bike
11 == Lorry (camion)
88 == Unknown
99 == Other
InjuryHx.InjRoadAccOtherPartyInvolved 0 == No
1 == Yes
88 == Unknown
InjuryHx.InjRoadAccOtherPartyOther
InjuryHx.InjRoadAccVictim 1 == Motor vehicle occupant
2 == Pedestrian
3 == Cyclist
4 == Moped/Scooter
5 == Motor Bike
99 == Other
Only if traffic accident
InjuryHx.InjRoadAccVictimOther
InjuryHx.InjRoadAccVictimVehiclePlace 1 == Driver
2 == Front seat passenger
3 == Back seat passenger
InjuryHx.InjSafetyAirbag 0 == No
1 == Yes
77 == Not Applicable
88 == Unknown
Only applicable if subject was motor vehicle occupant
InjuryHx.InjSafetyHelmet 0 == No
1 == Yes
77 == Not Applicable
88 == Unknown
Only applicable in case of cyclist, scooter, motorbike incident. However, may also have been scored for various sports injuries
InjuryHx.InjSafetySeatbelt 0 == No
1 == Yes
77 == Not Applicable
88 == Unknown
Only applicable if subject was motor vehicle occupant
InjuryHx.InjTeamSportType 1 == Football (soccer)
2 == Rugby
3 == Field Hockey
4 == Ice Hockey
5 == Lacrosse
99 == Other
Only applicable for sports/recreational injuries
InjuryHx.InjTeamSportTypeOther Only applicable for sports/recreational injuries
InjuryHx.InjType 1 == Closed
2 == Blast
3 == Crush
5 == Penetrating
6 == Penetrating-perforating
7 == Penetrating-tangential
8 == Closed with open depressed skull fracture
88 == Unknown
Details of Injury are captured in 4 different variables: Type of Injury, Place of Injury, Cause of Injury and Mechanism of injury.
InjuryHx.InjVictimAlcoholTestType Breath == Breath Test
Blood == Blood Test
InjuryHx.InjVictimBloodAlcoholmgdL
InjuryHx.InjVictimBloodAlcoholpermil
InjuryHx.InjVictimBloodAlcoholUnit 1 == mg/dL
2 == per mil (0/00)
InjuryHx.InjVictimDrugsTypeOther
InjuryHx.InjVictimSleepingPills 0 == No
1 == Suspect
2 == Definite
88 == Unknown
InjuryHx.InjVictimTypeDrugs 1 == Cannabis
2 == Cocaine
3 == Methamphetamine's
4 == Opioids
5 == XTC
88 == Unknown
99 == Other
InjuryHx.InjViolence 1 == Robbery
2 == Interpersonal violence (fight)
3 == Domestic assault
4 == Child abuse
5 == Gang violence
6 == Military deployment
88 == Unknown
99 == Other
Only applicable if violence cause of injury
InjuryHx.InjViolenceOther
InjuryHx.InjViolenceOtherPartyAlcohol 0 == No
1 == Definite
2 == Suspect
88 == Unknown
InjuryHx.InjViolenceOtherPartyDrugs 0 == No
1 == Definite
2 == Suspect
88 == Unknown
InjuryHx.InjViolenceVictimAlcohol 0 == No
1 == Definite
2 == Suspect
88 == Unknown
Information drug and alcohol abuse of possible influence on the incident is different for victim versus "other party" (if involved)
InjuryHx.InjViolenceVictimDrugs 0 == No
1 == Definite
2 == Suspect
88 == Unknown
InjuryHx.InterventRadiology 0 == No
1 == Yes
88 == Unknown
InjuryHx.LOCAOC 0 == No
1 == Yes, immediate
2 == Not tested due to LOC
3 == Suspected
4 == Yes, delayed onset
88 == Unknown
TBI may be present in the absence of LOC or PTA. Alteration of Consciousness (AOC) is then the main presenting symptom and considered diagnostic of TBI. Details of symptoms are captured in the Rivermead Questionnaire.
InjuryHx.LOCAOCDelayedHrs Only in case of delayed onset
InjuryHx.LOCAOCDelayedHrsUnk
InjuryHx.LOCAOCDuration 0 == None
2 == <1 minute
3 == 1-29 minutes
4 == 30-59 minutes
5 == 1-24 hours
6 == 1-7 days
7 == >7 days
88 == Unknown
InjuryHx.LOCAOCReportedBy 1 == Patient
2 == Witness
3 == Clinical interview
4 == Medical chart
5 == Not available
InjuryHx.LOCDuration 0 == No return of consciousness
2 == <1 minute
3 == 1-29 minutes
4 == 30-59 minutes
5 == 1-24 hours
6 == 1-7 days
7 == >7 days
88 == Unknown
Note: for patients admitted to hospital, the time to obeying commands is documented on hospital discharge: Hospital.HospDischargeTimeToObeyCommands
InjuryHx.LOCGCSSumDet 0 == None
1 == 1 point
2 == 2 or more points
88 == Unknown
InjuryHx.LOCLossOfConsciousness 0 == No
1 == Yes
3 == Suspected
88 == Unknown
Loss of Consciousness (LOC) is a definite sign of TBI. However, TBI may be present without any LOC. Presence and duration is captured.
InjuryHx.LOCLucidInterval 0 == No
1 == Yes
88 == Unknown
Lucid Interval is defined as a temporary improvement in a patient's condition after a traumatic brain injury, after which the condition deteriorates. A lucid interval is especially indicative of an epidural hematoma. An estimated 20 to 50% of patients with epidural hematoma experience such a lucid interval.
InjuryHx.LOCLucidIntervalHrs
InjuryHx.LOCLucidIntervalHrsUnk
InjuryHx.LOCPTA 0 == No
1 == Yes, ongoing
2 == Yes, resolved
3 == Suspected
88 == Unknown
Post-traumatic amnesia (PTA) is the period after the injury that the patient cannot remember. In contrast to retrograde amnesia, the duration of PTA remains constant over time. To document presence/absence of PTA on discharge from the ER, the GOAT questionnaire is requested: Outcomes.GOATDate
InjuryHx.LOCPTADuration 0 == None
2 == <1 hour
5 == 1-24 hours
6 == 1-7 days
7 == 7-28 days
8 == 1-2 hours
9 == 2-4 hours
10 == 4-24 hours
11 == >1 day
28 == >28
77 == N/A (e.g. death)
88 == Unknown
Only if PTA is yes. The duration of PTA reflects the severity of TBI. In patients with more sever TBI, the duration of PTA cannot be determined on presentation. For patients admitted to hospital, the duration of TBI in days is also captured on hospital discharge:.Hospital.HospDischPTADays
InjuryHx.LOCPTAReportedBy 1 == Patient
2 == Witness
3 == Retrospective assessment/ clinical interview
4 == Medical chart
5 == Not available
6 == Prospective assessment with PTA scale
InjuryHx.LOCPTAScale 1 == GOAT
2 == Westmead
3 == O-Log
4 == Nijmegen PTA scale
99 == Other
In some centres, prospective assessment of amnesia after TBI is performed using a dedicated scale. This variable documents the scale used.
InjuryHx.LOCReportedBy 1 == Self report
2 == Witness
3 == Clinical interview
4 == Medical chart
5 == Not available
Documentation of LOC can be subjective. We therefore asked for "source of verification"
InjuryHx.LOCRGA 0 == No
1 == Yes
88 == Unknown
Amnesia after injury is a sign of TBI. Retrograde amnesia is the period before the injury that the patient cannot remember. The duration of retrograde amnesia becomes shorter as the injury is longer ago. The duration of retrograde amnesia is therefore dependent on time after injury at which it was assessed.
InjuryHx.LOCRGADur 0 == None
1 == <30
2 == >= 30 minutes
88 == Unknown
InjuryHx.LOCRGAReportBy 1 == Self report
2 == Witness
3 == Clinical interview
4 == Medical chart
5 == Not available
InjuryHx.LowerExtremitiesAIS 0 == 0
1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
Lower extremities as subdomain of Extremities and pelvic girdle
InjuryHx.LowerExtremitiesDesc 1 == Femoral fracture
2 == Tibia plateau fracture
3 == Tibia fracture
4 == Ankle fracture
5 == Calcaneus fracture
6 == Metatarsal/tarsal fracture (toe fracture)
7 == Fibula fracture
InjuryHx.LumbarSpineAIS 0 == 0
1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
Lumbar spine as subdomain of Abdomen/Pelvic contents
InjuryHx.LumbarSpineDesc 1 == Fracture
2 == Dislocation
3 == Sacral fracture
99 == Other
InjuryHx.NeuroAssmtsAVPU U == The patient is completely unresponsive
A == Patient is awake
V == Patient responds to verbal stimulation
P == The patient responds to painful stimulation
88 == Unknown
The AVPU scale (an acronym from "alert, voice, pain, unresponsive") is a system by which a health care professional can measure and record a patient's responsiveness, indicating their level of consciousness.
InjuryHx.PainScale
InjuryHx.PainScaleUnk 77 == Untestable
88 == Unknown
InjuryHx.PelvicGirdleAIS 0 == 0
1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
Pelvic Girdle as subdomain of Extremities and pelvic girdle
InjuryHx.PelvicGirdleDesc 1 == Pelvic fracture
2 == Hip fracture
3 == Hip dislocation
InjuryHx.PreHospAssmtConditions 0 == No sedation or paralysis
1 == Sedated
2 == Paralyzed
3 == Temporary stop of sedation/paralysis
4 == Reversal of sedation/paralysis
5 == Active reversal (pharmacologic) of sedation/paralysis
99 == Other
Describes the condition under which the GCS was assessed.
InjuryHx.PresArrivalMethod 1 == Ambulance
2 == Helicopter
3 == Medical mobile team
4 == Walk in or drop off
99 == Other
InjuryHx.PresCirculationTreatmentCPR CPR = Cardio-pulmonary resuscitation
InjuryHx.PresCirculationTreatmentIVFluids
InjuryHx.PresCirculationTreatmentNone
InjuryHx.PresCirculationTreatmentUnknown
InjuryHx.PresCTBrain 0 == No
1 == Yes
88 == Unknown
Procedure performed at first hospital (not study hospital).
InjuryHx.PresEmergencyCare 0 == None
1 == Untrained person (by stander)
2 == Trainer/coach
3 == Military, non-medic
4 == Paramedic
5 == Nurse
6 == Physician
7 == Medical rescue team
99 == Other
InjuryHx.PresEmergencyCareIntubation 0 == No
1 == Yes
88 == Unknown
InjuryHx.PresEmergencyCareSuppOxygen 0 == No
1 == Yes
88 == Unknown
InjuryHx.PresEmergencyCareVentilation 0 == No
1 == Yes
88 == Unknown
InjuryHx.PresEmergencyServiceAmbuBasic
InjuryHx.PresEmergencyServiceAmbuSpec
InjuryHx.PresEmergencyServiceFirefighter
InjuryHx.PresEmergencyServiceHelicopter
InjuryHx.PresEmergencyServiceNone
InjuryHx.PresEmergencyServicePolice
InjuryHx.PresERExtracranialSurg 0 == No
1 == Yes
88 == Unknown
Procedure performed at first hospital (not study hospital).
InjuryHx.PresERIntracranialSurg 0 == No
1 == Yes
88 == Unknown
Procedure performed at first hospital before arrival to the study hospital. Surgical procedures decided on to perform directly on arrival to the study hospital are recorded within InjuryHx.EmergSurgInterventionsIntraCran.
InjuryHx.PresFHospDate First hospital is defined as the initial hospital to which the patient was brought before being transferred to Study hospital. Consequently, only applicable in case of secondary transferral. However, in some sites data for first hospital may have been entered also when the patient was brought directly to the study hospital..
InjuryHx.PresFHospTime
InjuryHx.PresFirstOnSceneDate
InjuryHx.PresFirstOnSceneDepartUnknownTime 77 == N/A if emergency service=none
88 == Unknown
InjuryHx.PresFirstOnSceneDepartureDate
InjuryHx.PresFirstOnSceneDepartureTime
InjuryHx.PresFirstOnSceneTime
InjuryHx.PresFirstOnSceneUnknownTime 77 == N/A if emergency service=none
88 == Unknown
Time of arrival of EMS to incident scene unknown or N/A (f.e. if no EMS involved)
InjuryHx.PresIntubation 0 == No
1 == Yes
88 == Unknown
Procedure performed at first hospital (not study hospital).
InjuryHx.PresSTHospDate
InjuryHx.PresSTHospTime
InjuryHx.PresTBIRef 1 == Primary
2 == Secondary
InjuryHx.PupilsBaselineDerived 0 - Both reacting
1 - One reacting (other pupil is either unreactive, missing or untestable)
2 - Both unreacting
This is a derived variable calculated centrally. Number of reactive pupils for baseline risk adjustment with missing values imputed using IMPACT methodology- take Poststabilisation value and if absent work back in time towards prehospital values until non-missing value found. Untestable pupil ignored: I.e. 1 reactive + 1 untestable = 1 reactive (this assumption applies only to a small proportion of the data). RECOMMENDED FOR BASELINE RISK ADJUSTMENT.
InjuryHx.PupilsNonSymmetric Pupil symmetry derived variable calculated from (GCSFirstHospPupilSymmetry,EDArrPupilSymmetry,GCSPreHospPupilSymmetry,EDDischPupilSymmetry,PupilsNonSymmetric)
InjuryHx.SedativeCurrentUse 0 == No
1 == Yes
88 == Unknown
InjuryHx.SedativePriorUse 0 == No
1 == Yes
88 == Unknown
InjuryHx.SedativePriorUseDuration Only applicable if use marked "yes"
InjuryHx.SympSkullFract 0 == No
1 == Yes
88 == Unknown
InjuryHx.SympVomiting 0 == No
1 == Once
2 == More than once
88 == Unknown
InjuryHx.ThoracicSpineAIS 0 == 0
1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
InjuryHx.ThoracicSpineDesc 1 == Fracture
2 == Dislocation
Thoracic spine as subdomain of Thorax/Chest
InjuryHx.ThoraxChestAIS 0 == 0
1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
InjuryHx.ThoraxChestDesc 1 == Rib fracture
2 == Lung contusion
3 == Cardiac contusion
4 == Aorta dissection
5 == Pneumo-thorax
6 == Hemato-thorax
99 == Other
InjuryHx.TobcoCurntUseInd 0 == No
1 == Yes
88 == Unknown
Use in the past 3 months
InjuryHx.TobcoPriorUseInd 0 == No
1 == Yes
88 == Unknown
The form "Behavioral History" captures information on past and current use of alcohol, tobacco, sedatives/sleeping pills, cannabis and other recreational drugs. Use is differentiated as "Past user" (eg stopped) versus "use in the past 3 months. Note: These variables do not reflect use of these substances at the time of injury.
InjuryHx.TobcoUseDur
InjuryHx.TotalISS The Injury Severity Score is calculated as the sum of the squares of the the 3 body regions with the highest AIS score. The max score for the ISS = 75. If any body region AIS is assigned a score of "6", the ISS is automatically set to 75 (highest score). In the calculation of the ISS, only the 6 main body regions are taken into consideration.
InjuryHx.UpperExtremitiesAIS 0 == 0
1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
Upper extremities as subdomain of Extremities and pelvic girdle
InjuryHx.UpperExtremitiesDesc 1 == Humerus fracture
2 == Radial and/or ulnar fracture
3 == Dislocation
4 == Hand
5 == Finger
Labs.DLA10Extem Only applicable to sites doing ROTEM studies
Labs.DLA10Fibtem Only applicable to sites doing ROTEM studies
Labs.DLA10NotDone Only applicable to sites doing ROTEM studies
Labs.DLA5Extem Only applicable to sites doing ROTEM studies
Labs.DLA5Fibtem Only applicable to sites doing ROTEM studies
Labs.DLA5NotDone Only applicable to sites doing ROTEM studies
Labs.DLaAngleExtem Only applicable to sites doing ROTEM studies
Labs.DLaAngleFibtem Only applicable to sites doing ROTEM studies
Labs.DLaAngleNotDone Only applicable to sites doing ROTEM studies
Labs.DLACT Only applicable to sites doing ROTEM/TEG studies
Labs.DLACTNotDone Only applicable to sites doing ROTEM/TEG studies
Labs.DLADPAggreg Only applicable to sites doing multiplate studies
Labs.DLADPAUC Only applicable to sites doing multiplate studies
Labs.DLADPAUCU Only applicable to sites doing multiplate studies
Labs.DLADPVelocity Only applicable to sites doing multiplate studies
Labs.DLAlatSgptNotDone
Labs.DLAlatSgptOther Preferred unit for ALAT/SGPT was U/L. When sites used another unit, the value was recorded here.
Labs.DLAlatSgptOtherUnit Preferred unit for ALAT/SGPT was U/L. When sites used another unit, the other unit was recorded here.
Labs.DLAlatSgptUL Recorded in "preferred" units
Labs.DLAlbumingL Recorded in "preferred" units
Labs.DLAlbuminNotDone
Labs.DLAlbuminOther Preferred unit for Albumin was g/L. When sites used another unit, the value was recorded here.
Labs.DLAlbuminOtherUnit Preferred unit for Albumin was g/L. When sites used another unit, the other unit was recorded here.
Labs.DLAlkalinePhosphataseNotDone
Labs.DLAlkalinePhosphataseOther Preferred unit for Alkaline Phosphatase was U/L. When sites used another unit, the value was recorded here.
Labs.DLAlkalinePhosphataseOtherUnit Preferred unit for Alkaline Phosphatase was U/L. When sites used another unit, the other unit was recorded here.
Labs.DLAlkalinePhosphataseUL Recorded in "preferred" units
Labs.DLAmylaseNotDone
Labs.DLAmylaseOther Preferred unit for Amylase was U/L. When sites used another unit, the value was recorded here.
Labs.DLAmylaseOtherUnit Preferred unit for Amylase was U/L. When sites used another unit, the other unit was recorded here.
Labs.DLAmylaseUL Recorded in "preferred" units
Labs.DLaPttNotDone
Labs.DLaPttOther Preferred unit for aPTT was sec. When sites used another unit, the value was recorded here.
Labs.DLaPttOtherUnit Preferred unit for aPTT was sec. When sites used another unit, the other unit was recorded here.
Labs.DLaPttsec Recorded in "preferred" units
Labs.DLAsatSgotNotDone
Labs.DLAsatSgotOther Preferred unit for ASAT/SGOT was U/L. When sites used another unit, the value was recorded here.
Labs.DLAsatSgotOtherUnit Preferred unit for ASAT/SGOT was U/L. When sites used another unit, the other unit was recorded here.
Labs.DLAsatSgotUL Recorded in "preferred" units
Labs.DLASPIAggreg Only applicable to sites doing multiplate studies
Labs.DLASPIAUC Only applicable to sites doing multiplate studies
Labs.DLASPIAUCU Only applicable to sites doing multiplate studies
Labs.DLASPIVelocity Only applicable to sites doing multiplate studies
Labs.DLBloodChemDone
Labs.DLCalciummmolL Recorded in "preferred" units
Labs.DLCalciumNotDone
Labs.DLCalciumOther Preferred unit for Calcium was mmol/L. When sites used another unit, the value was recorded here.
Labs.DLCalciumOtherUnit Preferred unit for Calcium was mmol/L. When sites used another unit, the other unit was recorded here.
Labs.DLCFTExtem Only applicable to sites doing ROTEM studies
Labs.DLCFTFibtem Only applicable to sites doing ROTEM studies
Labs.DLCFTNotDone Only applicable to sites doing ROTEM studies
Labs.DLCL30
Labs.DLCL30NotDone
Labs.DLCL60
Labs.DLCL60NotDone
Labs.DLCLTExtem Only applicable to sites doing ROTEM studies
Labs.DLCLTFibtem Only applicable to sites doing ROTEM studies
Labs.DLCLTNotDone Only applicable to sites doing ROTEM studies
Labs.DLCOLAggreg Only applicable to sites doing multiplate studies
Labs.DLCOLAUC Only applicable to sites doing multiplate studies
Labs.DLCOLAUCU Only applicable to sites doing multiplate studies
Labs.DLCOLVelocity Only applicable to sites doing multiplate studies
Labs.DLCreatinineNotDone
Labs.DLCreatinineOther Preferred unit for Creatinine was µmol/L. When sites used another unit, the value was recorded here.
Labs.DLCreatinineOtherUnit Preferred unit for Creatinine was µmol/L. When sites used another unit, the other unit was recorded here.
Labs.DLCreatinineumolL Recorded in "preferred" units
Labs.DLCRPmgL Recorded in "preferred" units
Labs.DLCRPNotDone
Labs.DLCRPOther Preferred unit for CRP was mg/L. When sites used another unit, the value was recorded here.
Labs.DLCRPOtherUnit Preferred unit for CRP was mg/L. When sites used another unit, the other unit was recorded here.
Labs.DLCTExtem Only applicable to sites doing ROTEM studies
Labs.DLCTFibtem Only applicable to sites doing ROTEM studies
Labs.DLCTNotDone Only applicable to sites doing ROTEM studies
Labs.DLDate
Labs.DLDdimersNotDone
Labs.DLDdimersOther Preferred unit for D-dimers was µg/L. When sites used another unit, the value was recorded here.
Labs.DLDdimersOtherUnit Preferred unit for D-dimers was µg/L. When sites used another unit, the other unit was recorded here.
Labs.DLDdimersugL Recorded in "preferred" units
Labs.DLEosinophilsNotDone
Labs.DLEosinophilsOther Preferred unit for Eosinophils was %. When sites used another unit, the value was recorded here.
Labs.DLEosinophilsOtherUnit Preferred unit for Eosinophils was %. When sites used another unit, the other unit was recorded here.
Labs.DLEosinophilspct Recorded in "preferred" units
Labs.DLEPL
Labs.DLEPLNotDone
Labs.DLFibrinogenmgdL Recorded in "preferred" units
Labs.DLFibrinogenNotDone
Labs.DLFibrinogenOther Preferred unit for Fibrinogen was mg/dL. When sites used another unit, the value was recorded here.
Labs.DLFibrinogenOtherUnit Preferred unit for Fibrinogen was mg/dL. When sites used another unit, the other unit was recorded here.
Labs.DLGlucosemmolL Recorded in "preferred" units
Labs.DLGlucoseNotDone
Labs.DLGlucoseOther Preferred unit for Glucose was mmol/L. When sites used another unit, the value was recorded here.
Labs.DLGlucoseOtherUnit Preferred unit for Glucose was mmol/L. When sites used another unit, the other unit was recorded here.
Labs.DLHaematologyDone
Labs.DLHematocritNotDone
Labs.DLHematocritOther Preferred unit for Hematocrit was %. When sites used another unit, the value was recorded here.
Labs.DLHematocritOtherUnit Preferred unit for Hematocrit was %. When sites used another unit, the other unit was recorded here.
Labs.DLHematocritpct Recorded in "preferred" units
Labs.DLHemoglobingdL Recorded in "preferred" units
Labs.DLHemoglobinNotDone
Labs.DLHemoglobinOther Preferred unit for Hemoglobin was g/dL. When sites used another unit, the value was recorded here.
Labs.DLHemoglobinOtherUnit Preferred unit for Hemoglobin was g/dL. When sites used another unit, the other unit was recorded here.
Labs.DLInr
Labs.DLInrNotDone Recorded in "preferred" units
Labs.DLInrOther
Labs.DLInrOtherUnit
Labs.DLK
Labs.DLKNotDone
Labs.DLLabsNotDone Only hospital labs
Labs.DLLabsNotDoneOther
Labs.DLLdhNotDone
Labs.DLLdhOther Preferred unit for LDH was U/L. When sites used another unit, the value was recorded here.
Labs.DLLdhOtherUnit Preferred unit for LDH was U/L. When sites used another unit, the other unit was recorded here.
Labs.DLLdhUL Recorded in "preferred" units
Labs.DLLY30Extem Only applicable to sites doing ROTEM studies
Labs.DLLY30Fibtem Only applicable to sites doing ROTEM studies
Labs.DLLY30NotDone Only applicable to sites doing ROTEM studies
Labs.DLLY60Extem Only applicable to sites doing ROTEM studies
Labs.DLLY60Fibtem Only applicable to sites doing ROTEM studies
Labs.DLLY60NotDone Only applicable to sites doing ROTEM studies
Labs.DLLymphocytesNotDone
Labs.DLLymphocytesOther Preferred unit for Lymphocytes was %. When sites used another unit, the value was recorded here.
Labs.DLLymphocytesOtherUnit Preferred unit for Lymphocytes was %. When sites used another unit, the other unit was recorded here.
Labs.DLLymphocytespct Recorded in "preferred" units
Labs.DLMA
Labs.DLMagnesiummmolL Recorded in "preferred" units
Labs.DLMagnesiumNotDone
Labs.DLMagnesiumOther Preferred unit for Magnesium was mmol/L. When sites used another unit, the value was recorded here.
Labs.DLMagnesiumOtherUnit Preferred unit for Magnesium was mmol/L. When sites used another unit, the other unit was recorded here.
Labs.DLMANotDone
Labs.DLMCFExtem Only applicable to sites doing ROTEM studies
Labs.DLMCFFibtem Only applicable to sites doing ROTEM studies
Labs.DLMCFNotDone Only applicable to sites doing ROTEM studies
Labs.DLMCFtExtem Only applicable to sites doing ROTEM studies
Labs.DLMCFtFibtem Only applicable to sites doing ROTEM studies
Labs.DLMCFtNotDone Only applicable to sites doing ROTEM studies
Labs.DLMLExtem Only applicable to sites doing ROTEM studies
Labs.DLMLFibtem Only applicable to sites doing ROTEM studies
Labs.DLMLNotDone Only applicable to sites doing ROTEM studies
Labs.DLMultiplateDone Only in selected sites
Labs.DLNeutrophilsNotDone
Labs.DLNeutrophilsOther Preferred unit for Neutrophils was %. When sites used another unit, the value was recorded here.
Labs.DLNeutrophilsOtherUnit Preferred unit for Neutrophils was %. When sites used another unit, the other unit was recorded here.
Labs.DLNeutrophilspct Recorded in "preferred" units
Labs.DLPlatelet10_5L Recorded in "preferred" units
Labs.DLPlateletNotDone
Labs.DLPlateletOther Preferred unit for Platelet was X109/L or X103/μL. When sites used another unit, the value was recorded here.
Labs.DLPlateletOtherUnit Preferred unit for Platelet was X109/L or X103/μ. When sites used another unit, the other unit was recorded here.
Labs.DLPotassiummmolL Recorded in "preferred" units
Labs.DLPotassiumNotDone
Labs.DLPotassiumOther Preferred unit for Potassium was mmol/L. When sites used another unit, the value was recorded here.
Labs.DLPotassiumOtherUnit Preferred unit for Potassium was mmol/L. When sites used another unit, the other unit was recorded here.
Labs.DLProthrombineTimeNotDone
Labs.DLProthrombineTimeOther Preferred unit for Prothrombine Time was sec. When sites used another unit, the value was recorded here.
Labs.DLProthrombineTimeOtherUnit Preferred unit for Prothrombine Time was sec. When sites used another unit, the other unit was recorded here.
Labs.DLProthrombineTimeSec Recorded in "preferred" units
Labs.DLR
Labs.DLRISTOAggreg Only applicable to sites doing multiplate studies
Labs.DLRISTOAUC Only applicable to sites doing multiplate studies
Labs.DLRISTOAUCU Only applicable to sites doing multiplate studies
Labs.DLRISTOVelocity Only applicable to sites doing multiplate studies
Labs.DLRNotDone Only applicable to sites doing TEG studies
Labs.DLROTEMDone Only applicable to sites doing ROTEM tests
Labs.DLS100BNotDone
Labs.DLS100BOther Preferred unit for S100B was µg/L. When sites used another unit, the value was recorded here.
Labs.DLS100BOtherUnit Preferred unit for S100B was µg/L. When sites used another unit, the other unit was recorded here.
Labs.DLS100BugL Recorded in "preferred" units
Labs.DLSodiummmolL Recorded in "preferred" units
Labs.DLSodiumNotDone
Labs.DLSodiumOther Preferred unit for Sodium mmol/L. When sites used another unit, the value was recorded here.
Labs.DLSodiumOtherUnit Preferred unit for Sodium mmol/L. When sites used another unit, the other unit was recorded here.
Labs.DLTEGA10
Labs.DLTEGA10NotDone
Labs.DLTEGA5
Labs.DLTEGA5NotDone
Labs.DLTEGaAngle
Labs.DLTEGaAngleNotDone
Labs.DLTEGDone Only applicable for sites doing TEG
Labs.DLTEGType
Labs.DLTime
Labs.DLTMA
Labs.DLTMANotDone
Labs.DLTotalBilirubinNotDone
Labs.DLTotalBilirubinOther Preferred unit for Total Bilirubin was µmol/L. When sites used another unit, the value was recorded here.
Labs.DLTotalBilirubinOtherUnit Preferred unit for Total Bilirubin was µmol/L. When sites used another unit, the other unit was recorded here.
Labs.DLTotalBilirubinumolL Recorded in "preferred" units
Labs.DLToxScreen Only if performed as part of clinical routine
Labs.DLToxScreenDone Only if performed as part of clinical routine
Labs.DLToxScreenPosAmphet Only if performed as part of clinical routine
Labs.DLToxScreenPosBarb Only if performed as part of clinical routine
Labs.DLToxScreenPosBenzo Only if performed as part of clinical routine
Labs.DLToxScreenPosCannabis Only if performed as part of clinical routine
Labs.DLToxScreenPosCocaine Only if performed as part of clinical routine
Labs.DLToxScreenPosMeth Only if performed as part of clinical routine
Labs.DLToxScreenPosMethaqual Only if performed as part of clinical routine
Labs.DLToxScreenPosOpiate Only if performed as part of clinical routine
Labs.DLToxScreenPosOther Only if performed as part of clinical routine
Labs.DLToxScreenPosOtherTxt
Labs.DLToxScreenPosPhency Only if performed as part of clinical routine
Labs.DLToxScreenType Only if performed as part of clinical routine
Labs.DLTRAPAggreg Only applicable to sites doing multiplate studies
Labs.DLTRAPAUC Only applicable to sites doing multiplate studies
Labs.DLTRAPAUCU Only applicable to sites doing multiplate studies
Labs.DLTRAPVelocity Only applicable to sites doing multiplate studies
Labs.DLTTL
Labs.DLTTLNotDone
Labs.DLUreammolL Recorded in "preferred" units
Labs.DLUreaNotDone
Labs.DLUreaOther Preferred unit for Urea was mmol/L. When sites used another unit, the value was recorded here.
Labs.DLUreaOtherUnit Preferred unit for Urea was mmol/L. When sites used another unit, the other unit was recorded here.
Labs.DLWhiteBloodCellNotDone
Labs.DLWhiteBloodCellOther Preferred unit for White Blood Cell was X109/L or X103/μL. When sites used another unit, the value was recorded here.
Labs.DLWhiteBloodCellOtherUnit Preferred unit for White Blood Cell was X109/L or X103/μL. When sites used another unit, the other unit was recorded here.
Labs.DLWhiteBloodCellpct Recorded in "preferred" units
LabSampling.LSBiomarkersCollctnDate Protein biomarker sampling is planned in all 5400 subjects. 1 x 9ml blood sample was collected in a serum separator tube. After 45 minutes (±15) of coagulation at room temperature, it is centrifuged at 1500g for 10 minutes, 8 x 0.5ml of serum is then aliquoted into barcoded 1.8 ml blue capped cryovials. Note that blood sampling required specific informed consent. This was not provided by all subjects, and in others was not possible for logistic reasons.
LabSampling.LSBiomarkersCollctnTime
LabSampling.LSBiomarkersFreezerCollctnDate
LabSampling.LSBiomarkersFreezerCollctnTime
LabSampling.LSBiomarkersNotCollReason 1 == No informed consent
2 == Blood draw not successful
3 == Logistic reasons
LabSampling.LSBloodTransBfSampl 0 == No
1 == Yes
99 == Unknown
LabSampling.LSCoagulationCollctnDate Central haemostasis investigations are complementary to routine tests performed by local laboratories at participating sites and were performed in selected centres. This involves the collection of blood into: 1 x 2.7 ml potassium EDTA tube and 1 x 10 ml and 1 x 5 ml sodium-citrate tubes at the enrolment time points for 600 subjects from the admission stratum and 600 subjects from the ICU stratum. Post-op samples (300 cases) and Day 2 samples will also be obtained in the same two sodium citrate tubes from 600 ICU subjects (at this sampling point no potassium EDTA tubes/samples are requested).
LabSampling.LSCoagulationCollctnTime
LabSampling.LSCoagulationFreezerDate
LabSampling.LSCoagulationFreezerTime
LabSampling.LSGeneticCollctnDate Two genetic samples should be obtained in all CENTER-TBI participants. It is recognised by the CENTER-TBI coordinators that obtaining genetic samples post transfusion could result in “chimerism” in the genotype and that this could persists for long periods after trauma. However, the coordinators have taken a pragmatic view that samples should be taken at baseline when taking biomarker samples (+/- coagulation samples for those sites in the sub-study). This pragmatic approach has numerous advantages; it limits the complexity of the sampling regimen, reduces the need for repeat venepunctures and minimises the risk of missed samples if the participant is lost to follow-up. Accurate documentation of the participant’s transfusion status is essential for future analysis. In some cases blood sampling for genetic analysis were obtained later.
LabSampling.LSGeneticCollctnTime
LabSampling.LSGeneticFreezerDate
LabSampling.LSGeneticFreezerTime
LabSampling.LSGeneticNotCollReason 1 == No informed consent
2 == Blood draw not successful
3 == Logistic reasons
LabSampling.LSHospitalCollctnDate Sites were requested to document results of all routinely performed lab assessments at baseline, including where possible/applicable point-of-care testing. For patients with multiple labs at different times during the day, a new Lab form was created for each collection
LabSampling.LSHospitalCollctnTime
LabSampling.LSPointOfCareCollctnDate
LabSampling.LSPointOfCareCollctnTime
LabSampling.LSTissueCollctnDate
LabSampling.LSTissueCollctnTime
MedHx.AnticoagAntiThrombinProtein Medical history. Use of anticoagulant or platelet aggregation inhibitor by the patient. This variable describes the use of antithrombin protein therapeutics (Atryn).
MedHx.AnticoagCoumarin Medical history. Use of anticoagulant or platelet aggregation inhibitor by the patient. This variable describes the use of Coumarin derivative (Coumadin, Warfarin).
MedHx.AnticoagDirectThrombinInhib Medical history. Use of anticoagulant or platelet aggregation inhibitor by the patient. This variable describes the use of direct thrombin inhibitors (eg. dabigatran, argatroban, melagatran).
MedHx.AnticoagFactorXaInhib Medical history. Use of anticoagulant or platelet aggregation inhibitor by the patient. This variable describes the use of inhibitor of factor Xa (eg. rivaroxaban).
MedHx.AnticoagHeparin Medical history. Use of anticoagulant or platelet aggregation inhibitor by the patient. This variable describes the use of heparin.
MedHx.AnticoagLowMolHeparin Medical history. Use of anticoagulant or platelet aggregation inhibitor by the patient. This variable describes the use of low molecular weight heparin
MedHx.AnticoagulantOther Medical history. Use of anticoagulant or platelet aggregation inhibitor by the patient. This variable describes the use of another type of anticoagulant or platelet aggregation inhibitor, not specified elsewhere.
MedHx.AnticoagulantOtherTxt Medical history. Use of anticoagulant or platelet aggregation inhibitor by the patient. This variable describes the use of another type of anticoagulant or platelet aggregation inhibitor, not specified elsewhere. Text field.
MedHx.AnticoagulantReasonCardiac 0 == No
1 == Yes
Medical history. This variable is populated when the reason for using anticoagulants or platelet aggregation inhibitors by the patient is cardiac.
MedHx.AnticoagulantReasonCardiacCABG Medical history. This variable is populated when the reason for using anticoagulants or platelet aggregation inhibitors by the patient is cardiac, specifically CABG.
MedHx.AnticoagulantReasonCardiacFibrill Medical history. This variable is populated when the reason for using anticoagulants or platelet aggregation inhibitors by the patient is cardiac, specifically atrial fibrillation/flutter.
MedHx.AnticoagulantReasonCardiacStent Medical history. This variable is populated when the reason for using anticoagulants or platelet aggregation inhibitors by the patient is cardiac, specifically a cardiac stent.
MedHx.AnticoagulantReasonCardiacValve Medical history. This variable is populated when the reason for using anticoagulants or platelet aggregation inhibitors by the patient is cardiac, specifically a valve prosthesis.
MedHx.AnticoagulantReasonCardiovas 0 == N0
1 == Yes
Medical history. This variable is populated when the reason for using anticoagulants or platelet aggregation inhibitors by the patient is cardiovascular.
MedHx.AnticoagulantReasonCardiovasCarotidStent Medical history. This variable is populated when the reason for using anticoagulants or platelet aggregation inhibitors by the patient is cardiovascular, specifically a carotid or cerebral stent.
MedHx.AnticoagulantReasonCardiovasLimbIsch Medical history. This variable is populated when the reason for using anticoagulants or platelet aggregation inhibitors by the patient is cardiovascular, specifically limb ischaemia.
MedHx.AnticoagulantReasonCardiovasOtherStent Medical history. This variable is populated when the reason for using anticoagulants or platelet aggregation inhibitors by the patient is cardiovascular, specifically a stent not specified elsewhere.
MedHx.AnticoagulantReasonCardiovasStenosis Medical history. This variable is populated when the reason for using anticoagulants or platelet aggregation inhibitors by the patient is cardiovascular, specifically a cardiovascular stenosis
MedHx.AnticoagulantReasonCardiovasTIS Medical history. This variable is populated when the reason for using anticoagulants or platelet aggregation inhibitors by the patient is cardiovascular, specifically a transient ischaemic attack/stroke
MedHx.AnticoagulantReasonOther Medical history. This variable is populated when the reason for using anticoagulants or platelet aggregation inhibitors by the patient is not specified elsewhere.
MedHx.AnticoagulantReasonOtherTxt Medical history. This variable is populated when the reason for using anticoagulants or platelet aggregation inhibitors by the patient is not specified elsewhere (text field).
MedHx.AnticoagulantReasonThrombo 0 == No
1 == Yes
Medical history. This variable is populated when the reason for using anticoagulants or platelet aggregation inhibitors by the patient is thromboembolic.
MedHx.AnticoagulantReasonThromboDVTLess6 Medical history. This variable is populated when the reason for using anticoagulants or platelet aggregation inhibitors by the patient is thromboembolic, specifically a single episode of DVT (deep venous thrombosis) or PE (pulmonary embolism) <6 months.
MedHx.AnticoagulantReasonThromboDVTMore6 Medical history. This variable is populated when the reason for using anticoagulants or platelet aggregation inhibitors by the patient is thromboembolic, specifically a single episode of DVT (deep venous thrombosis) or PE (pulmonary embolism) >6 months.
MedHx.AnticoagulantReasonThromboMultipleEpisode Medical history. This variable is populated when the reason for using anticoagulants or platelet aggregation inhibitors by the patient is thromboembolic, specifically two or more episodes of DVT (deep venous thrombosis) or PE (pulmonary embolism).
MedHx.AnticoagXarelto Medical history. Use of anticoagulant or platelet aggregation inhibitor by the patient. This variable describes the use of Xarelto
MedHx.BetaBlocker 0 == No
1 == Yes
88 == Unknown
A specific question on the use of beta-blockers is included as some reports indicate better outcome with the use of beta blockers (Research interest Rotterdam). If yes, specification is requested and differentiated into: Non-selective blockers/Selective beta-1 blockers/alpha-1 and beta blockers.
MedHx.BetaBlockerAlphaBucundolol Medical history. Use of anticoagulant or platelet aggregation inhibitor by the patient. This variable describes the use of a beta blocker, specifically Bucindolol.
MedHx.BetaBlockerAlphaCarvedilol Medical history. Use of anticoagulant or platelet aggregation inhibitor by the patient. This variable describes the use of a beta blocker, specifically Carvedilol (Eucardic).
MedHx.BetaBlockerAlphaLabetolol Medical history. Use of anticoagulant or platelet aggregation inhibitor by the patient. This variable describes the use of a beta blocker, specifically Labetalol (Trandate).
MedHx.BetaBlockerAlphaOther Medical history. Use of anticoagulant or platelet aggregation inhibitor by the patient. This variable describes the use of an alpha 1 and beta-blocker, not specified elsewhere.
MedHx.BetaBlockerAlphaOtherTxt Medical history. Use of anticoagulant or platelet aggregation inhibitor by the patient. This variable describes the use of an alpha 1 and beta-blocker, not specified elsewhere (text field).
MedHx.BetaBlockerNonSelectCarteolol Medical history. Use of anticoagulant or platelet aggregation inhibitor by the patient. This variable describes the use of beta blockers, specifically Carteolol.
MedHx.BetaBlockerNonSelectNadolol Medical history. Use of anticoagulant or platelet aggregation inhibitor by the patient. This variable describes the use of beta blockers, specifically Nadolol
MedHx.BetaBlockerNonSelectOther Medical history. Use of anticoagulant or platelet aggregation inhibitor by the patient. This variable describes the use of beta blockers, nonselective, not specified elsewhere.
MedHx.BetaBlockerNonSelectOtherTxt Medical history. Use of anticoagulant or platelet aggregation inhibitor by the patient. This variable describes the use of beta blockers, nonselective, not specified elsewhere (textfield).
MedHx.BetaBlockerNonSelectPenbutolol Medical history. Use of anticoagulant or platelet aggregation inhibitor by the patient. This variable describes the use of beta blockers, specifically Penbutolo.
MedHx.BetaBlockerNonSelectPindolol Medical history. Use of anticoagulant or platelet aggregation inhibitor by the patient. This variable describes the use of beta blockers, specifically Pindolol (Viskeen)
MedHx.BetaBlockerNonSelectPropranolol Medical history. This variable describes the use of beta blockers, specifically Propranolol
MedHx.BetaBlockerNonSelectSotalol Medical history. This variable describes the use of beta blockers, specifically Sotalol (Sotacor)
MedHx.BetaBlockerSelectAcebutolol Medical history. This variable describes the use of beta blockers, specifically Acebutolol (Sectral)
MedHx.BetaBlockerSelectAtenolol Medical history. This variable describes the use of beta blockers, specifically Atenolol (Tenormin)
MedHx.BetaBlockerSelectBetaxolol Medical history. This variable describes the use of beta blockers, specifically Betaxolol (Kerlon)
MedHx.BetaBlockerSelectBisoprolol Medical history. This variable describes the use of beta blockers, specifically Bisoprolol (Emcor)
MedHx.BetaBlockerSelectCeliprolol Medical history. This variable describes the use of beta blockers, specifically Celiprolol (Dilanorm)
MedHx.BetaBlockerSelectEsmolol Medical history. This variable describes the use of beta blockers, specifically Esmolol (Brevibloc)
MedHx.BetaBlockerSelectMetoprolol Medical history. This variable describes the use of beta blockers, specifically Metoprolol (Selokeen).
MedHx.BetaBlockerSelectNebivolol Medical history. This variable describes the use of beta blockers, specifically Nebivolol (Nebilet)
MedHx.BetaBlockerSelectOther Medical history. This variable describes the use of beta blockers, specifically selective beta1blockers not specified elsewhere.
MedHx.BetaBlockerSelectOtherTxt Medical history. This variable describes the use of beta blockers, specifically selective beta1blockers not specified elsewhere (text field).
MedHx.MedHxAnticoagulantsOrPlatelet 0 == No
1 == Yes anticoagulants
2 == Yes platelet aggregation inhibitors
3 == Yes, both
88 == Unknown
Summary question to document if the subject was taking anticoagulants or platelet aggregation inhibitors prior to injury. If yes, details are requested concerning which (groups of) agents were used. This information is of high relevance in relation to the shift of epidemiologic patterns in TBI towards higher age (with more co-morbidities and medication).
MedHx.MedHxCardio 0 == No
1 == Yes
88 == Unknown
Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting cardiovascular medical history.
MedHx.MedHxCardioArrhythmia Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting cardiovascular medical history, specifically arrhythmia.
MedHx.MedHxCardioCongenitalHD Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting cardiovascular medical history, specifically congenital heart disease.
MedHx.MedHxCardioHTN Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting cardiovascular medical history, specifically hypertension
MedHx.MedHxCardioIschemicHD
MedHx.MedHxCardioNYHA IV == IV
III == III
II == II
I == I
A classification system for severity of cardiac disease - generally used for ischaemia, but used here in broader sense.
MedHx.MedHxCardioOther Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting cardiovascular medical history, not specified elsewhere.
MedHx.MedHxCardioOtherTxt Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting cardiovascular medical history, not specified elsewhere (textfield)
MedHx.MedHxCardioPeripheralVascular Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting cardiovascular medical history, specifically peripheral vascular disease.
MedHx.MedHxCardioThromboembolic Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting cardiovascular medical history, specifically thromboembolic
MedHx.MedHxCardioValvularHD Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting cardiovascular medical history, specifically valvular heart disease
MedHx.MedHxDevelopmental 0 == No
1 == Yes
88 == Unknown
Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting developmental diseases.
MedHx.MedHxDevelopmentalADDandADHD Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting developmental diseases, specifically attention deficit/hyperactivity disorder.
MedHx.MedHxDevelopmentalLearningDisability Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting developmental diseases, specifically learning disability
MedHx.MedHxDevelopmentalOther Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting developmental diseases that are not specified elsewhere.
MedHx.MedHxDevelopmentalOtherTxt Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting developmental diseases that are not specified elsewhere (textfield).
MedHx.MedHxEndocrine 0 == No
1 == Yes
88 == Unknown
Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting endocrine diseases
MedHx.MedHxEndocrineIDDM Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting endocrine diseases, specifically IDDM (Insulin dependent diabetes mellitus)
MedHx.MedHxEndocrineIDDMControl 1 == Well controlled
2 == Difficult controlled
88 == Unknown
MedHx.MedHxEndocrineNIDDM NIDDM: Non-insulin dependent diabetes mellitus
MedHx.MedHxEndocrineNIDDMControl 1 == Well controlled
2 == Difficult controlled
88 == Unknown
Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting endocrine diseases, specifically how well IDDM (Insulin dependent diabetes mellitus) is controlled.
MedHx.MedHxEndocrineOther Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting endocrine diseases not mentioned elsewhere.
MedHx.MedHxEndocrineOtherTxt Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting endocrine diseases not specified elsewhere (textfield).
MedHx.MedHxEndocrineThyroid Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting endocrine diseases, specifically thyroid disorder.
MedHx.MedHxENT 0 == No
1 == Yes
88 == Unknown
Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting ENT (Eye, Ear, Nose & Throat) disease
MedHx.MedHxENTHearing Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting ENT (Eye, Ear, Nose & Throat) disease, specifically hearing deficits.
MedHx.MedHxENTOther Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting ENT (Eye, Ear, Nose & Throat) diseases not specified elsewhere.
MedHx.MedHxENTOtherTxt Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting ENT (Eye, Ear, Nose & Throat) diseases not specified elsewhere (textfield).
MedHx.MedHxENTSinusitis Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting ENT (Eye, Ear, Nose & Throat) diseases, specifically sinusitis.
MedHx.MedHxENTVisionAbn Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting ENT (Eye, Ear, Nose & Throat) diseases, specifically vision.
MedHx.MedHxGastro 0 == No
1 == Yes
88 == Unknown
Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting gastrointestinal disease.
MedHx.MedHxGastroGERD Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting gastrointestinal disease, specifically GERD (Gastroesophageal Reflux Disease).
MedHx.MedHxGastroGIBleed Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting gastrointestinal disease, specifically gastrointestinal bleeding.
MedHx.MedHxGastroIBS Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting gastrointestinal disease, specifically inflammatory bowel disease.
MedHx.MedHxGastroOther Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting gastrointestinal disease not specified elsewhere.
MedHx.MedHxGastroOtherTxt Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting gastrointestinal disease not specified elsewhere (textfield).
MedHx.MedHxHematologic 0 == No
1 == Yes
88 == Unknown
Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting hematologic diseases.
MedHx.MedHxHematologicAIDS Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting hematologic diseases, specifically AIDS
MedHx.MedHxHematologicAnemia Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting hematologic diseases, like anemia.
MedHx.MedHxHematologicHIV Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting hematologic diseases, like HIV positive.
MedHx.MedHxHematologicOther Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting hematologic diseases, not specified elsewhere.
MedHx.MedHxHematologicOtherTxt Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting hematologic diseases, not specified elsewhere (textfield).
MedHx.MedHxHematologicSickleCell Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting hematologic diseases, specifically sickle cell disease.
MedHx.MedHxHepatic 0 == No
1 == Yes
88 == Unknown
Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting hepatic diseases.
MedHx.MedHxHepaticCirrhosis Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting hepatic diseases, specifically cirrhosis.
MedHx.MedHxHepaticFailure Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting hepatic diseases, specifically hepatic failure
MedHx.MedHxHepaticHepatitis Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting hepatic diseases, specifically hepatitis.
MedHx.MedHxHepaticInsufficiency Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting hepatic diseases, specifically hepatic insufficiency.
MedHx.MedHxHepaticOther Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting hepatic diseases not specified elsewhere
MedHx.MedHxHepaticOtherTxt Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting hepatic diseases not specified elsewhere (textfield)
MedHx.MedHxMusculoskeletal 0 == No
1 == Yes
88 == Unknown
Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting musculoskeletal diseases
MedHx.MedHxMusculoskeletalArthritis Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting musculoskeletal diseases, specifically arthritis
MedHx.MedHxMusculoskeletalOther Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting musculoskeletal diseases not specified elsewhere.
MedHx.MedHxMusculoskeletalOtherTxt Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting musculoskeletal diseases not specified elsewhere (textfield)
MedHx.MedHxNeuro 0 == No
1 == Yes
88 == Unknown
Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting neurological diseases.
MedHx.MedHxNeuroCerebrovascularAccident Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting neurological diseases, specifically cerebrovascular accidents.
MedHx.MedHxNeuroEpilepsyGeneralized Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting neurological diseases, specifically epilepsy (generalized).
MedHx.MedHxNeuroEpilepsyOther Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting neurological diseases, specifically epilepsy (other).
MedHx.MedHxNeuroEpilepsyPartial Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting neurological diseases, specifically epilepsy (partial).
MedHx.MedHxNeuroFebrileSeizures Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting neurological diseases, specifically febrile seizures (children).
MedHx.MedHxNeuroHeadache Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting neurological diseases, specifically headache (non migraine).
MedHx.MedHxNeuroMigraine
MedHx.MedHxNeuroMigraineFamHist Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting neurological diseases, specifically family history of migraine.
MedHx.MedHxNeuroOther Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting neurological diseases not specified elsewhere.
MedHx.MedHxNeuroOtherTxt Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting neurological diseases not specified elsewhere (textfield)
MedHx.MedHxNeuroPain 0 == No
1 == Yes
88 == Unknown
Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting neurological diseases not specified elsewhere (textfield)
MedHx.MedHxNeuroTIA Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting neurological diseases, specifically transient ischemic attacks
MedHx.MedHxOncologic 0 == No
1 == Yes
88 == Unknown
Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting oncologic diseases.
MedHx.MedHxOncologicBreast Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting oncologic diseases, like breast cancer.
MedHx.MedHxOncologicGI Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting oncologic diseases, specifically gastrointestinal cancer.
MedHx.MedHxOncologicKidney Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting oncologic diseases, specifically kidney cancer.
MedHx.MedHxOncologicLeukemia Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting oncologic diseases, specifically leukemia.
MedHx.MedHxOncologicLung Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting oncologic diseases, specifically lung cancer.
MedHx.MedHxOncologicLymphoma Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting oncologic diseases, specifically lymphoma.
MedHx.MedHxOncologicOther Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting oncologic diseases not specified elsewhere
MedHx.MedHxOncologicOtherTxt Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting oncologic diseases not specified elsewhere (textfield).
MedHx.MedHxOncologicProstate Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting oncologic, specifically prostate cancer.
MedHx.MedHxOther 0 == No
1 == Yes
Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting oncologic, specifically prostate cancer.
MedHx.MedHxOtherTxt Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting other medical history, not specified elsewhere (textfield)
MedHx.MedHxPreInjASAPSClass 1 == A normal healthy patient
2 == A patient with mild systemic disease
3 == A patient with severe systemic disease
4 == A patient with a severe systemic disease that is a constant threat to life
88 == Unknown
Preinjury ASAPS classification. Common classification system used in anaesthesia; denotes overall health
MedHx.MedHxPreTBIConcussions 0 == No
1 == Yes
88 == Unknown
Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting previous TBI/ concussions
MedHx.MedHxPreTBIConcussionsTotal Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting total number of previous TBI/ concussions
MedHx.MedHxPreTBIConcussionsTotalHosAdmit Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting total number of hospital admissions for previous TBI/ concussions
MedHx.MedHxPsychiatric 0 == No
1 == Yes
88 == Unknown
Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting total number of hospital admissions for previous TBI/ concussions
MedHx.MedHxPsychiatricAnx Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting psychiatric diseases, specifically anxiety.
MedHx.MedHxPsychiatricDep Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting psychiatric diseases, specifically depression.
MedHx.MedHxPsychiatricOther Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting psychiatric diseases not documented elsewhere.
MedHx.MedHxPsychiatricOtherTxt Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting psychiatric diseases not documented elsewhere (textfield).
MedHx.MedHxPsychiatricSchiz Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting psychiatric diseases, specifically schizophrenia.
MedHx.MedHxPsychiatricSleep Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting psychiatric diseases, specifically sleep disorders.
MedHx.MedHxPsychiatricSubstanceAbuse Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting psychiatric diseases, specifically substance abuse disorders.
MedHx.MedHxPulmonary 0 == No
1 == Yes
88 == Unknown
Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting pulmonary diseases
MedHx.MedHxPulmonaryAsthma Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting pulmonary diseases, specifically asthma.
MedHx.MedHxPulmonaryCOPD Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting pulmonary diseases, specifically COPD (Chronic Obstructive Pulmonary Disease)
MedHx.MedHxPulmonaryOther Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting pulmonary diseases not specified elsewhere.
MedHx.MedHxPulmonaryOtherTxt Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting pulmonary diseases not specified elsewhere (textfield).
MedHx.MedHxPulmonaryPneumonia Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting pulmonary diseases, specifically pneumonia.
MedHx.MedHxPulmonaryTB Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting pulmonary diseases, specifically tuberculosis.
MedHx.MedHxRenal 0 == No
1 == Yes
88 == Unknown
Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting renal diseases.
MedHx.MedHxRenalFailure Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting renal diseases, specifically renal failure.
MedHx.MedHxRenalInsufficiency Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting renal diseases, specifically renal insufficiency.
MedHx.MedHxRenalOther Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting renal diseases not specified elsewhere.
MedHx.MedHxRenalOtherTxt Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting renal diseases not specified elsewhere (textfield).
MedHx.MedHxRenalUTI Details on Medical History are captured for 15 body regions/disease area's. If overall question for the body region/disease is "yes", more detailed info is requested and captured in the sub-domains. This variable is used for documenting renal diseases, specifically chronic UTI (urinary tract infection).
MedHx.PlateletAggreOther Medical history. Variable documents the use of anticoagulants or platelet aggregation inhibitors. This variable contains the medication of this type not specified elsewhere.
MedHx.PlateletAggreOtherTxt Medical history. Variable documents the use of anticoagulants or platelet aggregation inhibitors. This variable contains the medication of this type not specified elsewhere (textfield).
MedHx.PltAggregAdenosineInhib Medical history. Use of platelet aggregation inhibitor by the patient. This variable describes the use of an adenosine reuptake inhibitor (eg. Persantin, dipyridamole).
MedHx.PltAggregADPReceptInhib Medical history. Use of platelet aggregation inhibitor by the patient. This variable describes the use of ADP receptor inhibitors.
MedHx.PltAggregADPReceptInhibEffient Medical history. Use of platelet aggregation inhibitor by the patient. This variable describes the use of Parasugrel (Effient)
MedHx.PltAggregADPReceptInhibOther Medical history. Use of platelet aggregation inhibitor by the patient. This variable describes the use of ADP receptor inhibitors, not specified elsewhere.
MedHx.PltAggregADPReceptInhibOtherTxt Medical history. Use of platelet aggregation inhibitor by the patient. This variable describes the use of ADP receptor inhibitors, not specified elsewhere (textfield).
MedHx.PltAggregADPReceptInhibPlavix Medical history. Use of platelet aggregation inhibitor by the patient. This variable describes the use of Clopidogrel (Plavix).
MedHx.PltAggregADPReceptInhibTiclid Medical history. Use of platelet aggregation inhibitor by the patient. This variable describes the use of Ticlopidine (Ticlid).
MedHx.PltAggregAspirin Medical history. Use of platelet aggregation inhibitor by the patient. This variable describes the use of Aspirin
MedHx.PltAggregGlycoproteinInhib Medical history. Use of platelet aggregation inhibitor by the patient. This variable describes the use of glycoprotein IIB/IIIA inhibitors (eg. Aggrastat).
Medication.Agent 1 == Analgesic: paracetamol
2 == Analgesic: NSAIDs
3 == Analgesic: tramadol
4 == Analgesic: opioids (morphine, ect)
5 == Sedatives/treatment of agitation: barbiturates (penthothal, ect)
6 == Sedatives/treatment of agitation: clondine
7 == Sedatives/treatment of agitation: dexmedetomidine
8 == Sedatives/treatment of agitation: diazepam
9 == Sedatives/treatment of agitation: fentanyl
10 == Sedatives/treatment of agitation: haloperidol (haldol)
11 == Sedatives/treatment of agitation: lorazepam (tenesta, ect)
12 == Sedatives/treatment of agitation: midazolam
13 == Sedatives/treatment of agitation: morphine
14 == Sedatives/treatment of agitation: propofol
15 == Sedatives/treatment of agitation: other
16 == Neuromuscular blockade: pancuronium (pavulon)
17 == Neuromuscular blockade: atracurium (tracium)
18 == Neuromuscular blockade: cisatracurium (nimbex)
19 == Neuromuscular blockad: gallamine (flaxedil)
20 == Neuromuscular blockade: rocuronium (zemuron)
21 == Neuromuscular blockade: vecuronium (norcuron)
22 == Neuromuscular blockade: other
23 == Anti- epileptic: carbamazepine (tegretol)
24 == Anti- epileptic: lamotrigine (lamectal)
25 == Anti- epileptic: levetirazetam (keppra)
26 == Anti- epileptic: phenytoine (diphantoine)
27 == Anti- epileptic: valproate (depakine)
28 == Anti- epileptic: other
29 == Antibiotics: aminoglycoside (amikacine, gentamicine etc)
30 == Antibiotics: carbapemens (meronem etc)
31 == Antibiotics: cephalosporin 1st gen (cefalexin etc)
32 == Antibiotics: cephalosporin 2nd gen (cefuroxim etc)
33 == Antibiotics: cephalosporin 3rd gen (cefotaxine etc)
34 == Antibiotics: cephalosporin 4th gen (cefepime, maxipime etc)
35 == Antibiotics: cephalosporin 5th gen (ceftasoline etc)
36 == Antibiotics: glycopeptides (vancomycine)
37 == Antibiotics: lincosamides (clindamycine etc)
38 == Antibiotics: macrolidis (erythromycine etc)
39 == Antibiotics: nitrofurones (furoxone, furadantine etc)
40 == Antibiotics: penicillines (ampicilline, cloxacilline)
41 == Antibiotics: amoxycilline/clavulanic acid (augmentin, tyclav etc)
42 == Antibiotics: quinolones (ciprofloxacine etc)
43 == Antibiotics: sulfonamides (co-trimoxazole, doxycycline)
44 == Antibiotics: other
45 == Anti- hypertensive: ACE blockers (captopril, perindopril etc)
46 == Anti- hypertensive: angiotensininhibitors (cardesartan etc)
47 == Anti- hypertensive: bètablockers (propanolol)
48 == Anti- hypertensive: clonidine
49 == Anti- hypertensive: diuretics
50 == Calcium channel blockers: nimodipine
51 == Calcium channel blockers: nicardipine
52 == Calcium channel blockers: verapamil
53 == Steroids: methylprednisolone
54 == Steroids: bétametasone
55 == Steroids: dexametasone
56 == Steroids: hydrocortisone/cortisone
57 == Antacids: Aluminium hydroxide
58 == Antacids: other
59 == H2 receptor antagonist: Cimetidine
60 == H2 receptor antagonist: Ranitidine (Zantac)
61 == Proton pump inhibitors: Omeprazol (Losec)
62 == Proton pump inhibitors: Esomeprazol (Nexium)
63 == Proton pump inhibitors: Pantoprazole (Pantozol)
64 == Prokinetics: Domperidon (Motilium)
65 == Prokinetics: Erythromycin
66 == Prokinetics: Metoclopramide (Primperan)
67 == Analgesic: other
68 == Anti- hypertensive: other
69 == Calcium channel blockers: other
70 == Steroids: other
71 == H2 receptor antagonist: other
72 == Proton pump inhibitors: other
73 == Prokinetics:other
99 == Other, specify in Agent Other: Other
Medication.AgentOther
Medication.Class 1 == Analgesic
2 == Sedatives/treatment of agitation
3 == Neuromuscular blockade
4 == Anti- epileptic
5 == Antibiotics
6 == Anti- hypertensive
7 == Calcium channel blockers
8 == Steroids
9 == Antacids
10 == H2 receptor antagonist
11 == Proton pump inhibitors
12 == Prokinetics
99 == Other, specify in Agent Other
Classes: analgesic, sedatives, neuromuscular blocking agents, anti-epileptic drugs, antibiotiucs, anti-hypertensive, calcium channel blockers, steroids, antacids, H2 receptor antagonists, proton pump inhibitors and prokinetics. Agents commonly used for treatment of raised ICP are listed in the TIL section, but not included in the medication lists here.
Medication.HighestDailyDose These details should be entered for each agent
Medication.Ongoing These details should be entered for each agent; records if medication was still ongoing on discharge
Medication.Reason 1 == Sedatives/treatment of agitation: mechanical ventilation
2 == Sedatives/treatment of agitation: metabolic suppression
3 == Anti- epileptic: prophylaxis
4 == Anti- epileptic: treatment of overt seizure
6 == Anti- epileptic: treatment of (silent) seizure activity
7 == Antibiotics: fever, no clear focus
8 == Antibiotics: pneumonia
9 == Antibiotics: urinary tract infection
10 == Antibiotics: catheter related bloodstream infection
11 == Antibiotics: intracranial abces/empyeme
12 == Antibiotics: periprocedural prophylaxis
13 == Antibiotics: meningitis
14 == Anti- hypertensive: to lower blood pressure
15 == Anti- hypertensive: treatment agitation
16 == Calcium channel blockers: prevention of vasospasm
17 == Calcium channel blockers: treatment of vasospasm
18 == Calcium channel blockers: anti- hypertensive
19 == Calcium channel blockers: cardiac indication
20 == Steroids: traumatic brain injury
21 == Steroids: ARDS
22 == Steroids: hypopituitarism
23 == Steroids: sepsis
24 == Antacids: gastric protection
25 == Antacids: reflux
26 == H2 receptor antagonist: gastric protection
27 == H2 receptor antagonist: treatment of ulcer
28 == Proton pump inhibitors: gastric protection
29 == Proton pump inhibitors: treatment of ulcer
30 == Prokinetics: gastric retention
31 == Prokinetics: vomiting
32 == Prokinetics: constipation
33 == Prokinetics: routine care
35 == Analgesic: other
36 == Neuromuscular blockade: other
37 == Sedatives/treatment of agitation: Other
38 == Anti- epileptic: Other
39 == Antibiotics: Other
40 == Anti- hypertensive: Other
41 == Calcium channel blockers: Other
42 == Steroids: Other
43 == Antacids: Other
44 == H2 receptor antagonist: Other
45 == Proton pump inhibitors: Other
46 == Prokinetics: Other
99 == Other, specify in Agent Other: Other
These details should be entered for each agent
Medication.ReasonOther These details should be entered for each agent
Medication.Route ED == Epidural
IvCont == Continuous IV
IvInt == Intermittent IV
Ih == Inhaled
Re == Rectal
Im == Intramuscular
PO == Oral
Pv == Vaginal
To == Topical
Sc == Subcutaneous
These details should be entered for each agent
Medication.StartDate These details should be entered for each agent
Medication.StopDate These details should be entered for each agent
Meds.DVTMechOngoing
Meds.DVTPharmOngoing
Meds.DVTPharmType 1 == Heparin
2 == Low molecular weight Heparin
3 == Dalteparin (Fragmin)
4 == Enoxaparin
5 == Nadroparin (Fraxiparine, Fraxodil)
6 == Parnaparin
7 == Reviparin
8 == Tinzaparin
Meds.DVTProphylaxisMech 0 == No
1 == Yes
Meds.DVTProphylaxisMechStartDate
Meds.DVTProphylaxisMechStopDate
Meds.DVTProphylaxisMechType
Meds.DVTProphylaxisPharm 0 == No
1 == Yes
These variables aim to document specific information on the use of DVT prophylaxis. Little evidence exists on the use and timing of DVT prophylaxis after TBI, and considerable practice variation exists.
Meds.DVTProphylaxisStartDate
Meds.DVTProphylaxisStopDate
Meds.EnteralNutrition 0 == No
1 == Yes
Meds.EnteralNutritionRoute 1 == Nasogastric tube
2 == Transpyloric tube
3 == Gastrostomy
Meds.EnteralNutritionStartDate
Meds.EnteralNutritionStopDate
Meds.Intubation 0 == No
1 == Yes
Meds.IntubationStartDate
Meds.IntubationStartTime
Meds.IntubationStop 0 == No
1 == Yes
Meds.IntubationStopDate
Meds.IntubationStopReason 1 == Respiratory stable
2 == Accidental
3 == Withdrawal of care
Meds.IntubationStopTime
Meds.MechVentilation 0 == No
1 == Yes
Meds.MechVentilationStartDate
Meds.MechVentilationStartTime
Meds.MechVentilationStopDate
Meds.MechVentilationStopTime
Meds.Nasogastric 0 == No
1 == Yes
Meds.NasogastricOngoing
Meds.NasogastricStartDate
Meds.NasogastricStopDate
Meds.OxygenAdm 0 == No
1 == Yes
88 == Unknown
Meds.OxygenAdmOngoing
Meds.OxygenAdmStartDate
Meds.OxygenAdmStopDate
Meds.ParenteralNutrition 0 == No
1 == Yes
Meds.ParenteralNutritionStartDate These variables aim to document specific information on nutritional support, provided by parenteral and/or enteral routes.
Meds.ParenteralNutritionStopDate
Meds.PEGTube 0 == No
1 == Yes
Meds.PEGTubeOngoing
Meds.PEGTubeStartDate
Meds.PEGTubeStopDate
Meds.ReIntubation 0 == No
1 == Yes
Meds.ReIntubationStartDate
Meds.ReIntubationStartTime
Meds.ReMechVentilation 0 == No
1 == Yes
Meds.ReMechVentilationReason 1 == Respiratory failure
2 == Neurologic deterioration
3 == Spontaneous hyperventilation
4 == Sepsis
99 == Other
Meds.ReMechVentilationReasonOther
Meds.ReMechVentilationStartDate
Meds.ReMechVentilationStartTime
Meds.TakenMeds 0 == No
1 == Yes
Documentation of concomitant medication largely follows a pre-defined structure: A total of 12 classes of drugs are pre-defined, each with a drop-down menu of 1-15 most commonly used agents. The reason for prescribing, the highest daily dose&units as well as route of administration is documented. For agents not listed in the drop-down menu's, the option "other" permits free text entries.
Meds.Tracheostomy 0 == No
1 == Yes
Meds.TracheostomyOngoing
Meds.TracheostomyStartDate
Meds.TracheostomyStopDate
Meds.UrineCath 0 == No
1 == Yes
Meds.UrineCathOngoing
Meds.UrineCathStartDate
Meds.UrineCathStopDate
Meds.VentilationMgmtNA
Outcomes.10mWALKBestTestTime
Outcomes.10mWALKCompletionCode 1.0 == 1.0 Test completed in full
1.1 == 1.1 Non-standard adm - written
1.2 == 1.2 Non-standard adm - other
1.3 == 1.3 Test completed over the phone
2.1 == 2.1 Not completed - Cognitive/neuro
2.2 == 2.2 Not completed - Non-neuro/phys
2.3 == 2.3 Not completed - Poor effort
2.4 == 2.4 Not completed - Language
2.5 == 2.5 Not completed - Illness
2.6 == 2.6 Not completed - Logistical
3.1 == 3.1 Not attempted - Cognitive/neuro
3.2 == 3.2 Not attempted - Non-neuro/phys
3.3 == 3.3 Not attempted - Poor effort
3.4 == 3.4 Not attempted - Language
3.5 == 3.5 Not attempted - Illness
3.6 == 3.6 Not attempted - Logistical
4.0 == 4.0 Not attempted - Examiner error
5.0 == 5.0 Not attempted - Other
Outcomes.10mWALKDate
Outcomes.10mWALKTest1
Outcomes.10mWALKTest2
Outcomes.10mWALKTest3
Outcomes.10mWALKTestAttemptdNotCompOptions 2.1 == Not completed - Cognitive/neurological deficits
2.2 == Not completed - Non-neurological/physical reason
2.3 == Not completed - Lack of effort/uncooperative
2.4 == Not completed - Language
2.5 == Not completed - Illness/fatigue
2.6 == Not completed - Logistical reasons, other reasons
2.7 == Not completed - Examiner error
This variable describes why the test is attempted, but not completed.
Outcomes.10mWALKTestAttemptdNotCompOptionsOTHER This variable describes why the test is attempted, but not completed.
Outcomes.10mWALKTestCompletedOptions 3.0 == Test completed in full - results valid
3.1 == Test completed - Non-standard, results valid
3.2 == Non-standard administration - Other
Outcomes.10mWALKTestComplNonStandAdminOTHER
Outcomes.10mWALKTestNotDoneOptions 1.1 == Not attempted - Cognitive/neurological deficits
1.2 == Not attempted - Non-neurological/physical reasons
1.3 == Not attempted - Lack of effort/uncooperative
1.4 == Not attempted - Language
1.5 == Not attempted - Illness/fatigue
1.6 == Not attempted - Logistical reasons, other reasons
1.7 == Not attempted - Examiner error
1.8 == Not attempted - Patient not available
This variable describes the reason why the test is not done.
Outcomes.10mWALKTestNotDoneOptionsOTHER This variable describes why the test is not done.
Outcomes.10mWALKTUGNeuroPsychCompCode 1.0 == 1.0 Test not done
2.0 == 2.0 Test attempted but not completed
3.0 == 3.0 Test completed
This variable describes the completion status of the assessment.
Outcomes.CANTABAST 1.0 == 1.0 Test completed in full
1.1 == 1.1 Non-standard adm - written
1.2 == 1.2 Non-standard adm - other
1.3 == 1.3 Test completed over the phone
2.1 == 2.1 Not completed - Cognitive/neuro
2.2 == 2.2 Not completed - Non-neuro/phys
2.3 == 2.3 Not completed - Poor effort
2.4 == 2.4 Not completed - Language
2.5 == 2.5 Not completed - Illness
2.6 == 2.6 Not completed - Logistical
3.1 == 3.1 Not attempted - Cognitive/neuro
3.2 == 3.2 Not attempted - Non-neuro/phys
3.3 == 3.3 Not attempted - Poor effort
3.4 == 3.4 Not attempted - Language
3.5 == 3.5 Not attempted - Illness
3.6 == 3.6 Not attempted - Logistical
4.0 == 4.0 Not attempted - Examiner error
5.0 == 5.0 Not attempted - Other
For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTCompCode 1.0 == Test not done
2.0 == Test attempted, but not completed
3.0 == Test completed
Completion codes of CANTAB testings are not automatically filled in in the outcome assessment form. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTCongruencyCostMeanBlock3Correct Attention Switching Task (AST): The difference between the median latency of response (from stimulus appearance to button press) on the trials that were congruent versus the trials that were incongruent. Mean for correct trials in Block 3. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTCongruencyCostMeanBlock5Correct Attention Switching Task (AST): The difference between the median latency of response (from stimulus appearance to button press) on the trials that were congruent versus the trials that were incongruent. Mean for correct trials in Block 5. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTCongruencyCostMeanBlock7Correct Attention Switching Task (AST): The difference between the median latency of response (from stimulus appearance to button press) on the trials that were congruent versus the trials that were incongruent. Mean for correct trials in Block 7. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTCongruencyCostMeanCorrect Attention Switching Task (AST): The difference between the median latency of response (from stimulus appearance to button press) on the trials that were congruent versus the trials that were incongruent. Mean for all correct trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTCongruencyCostMedianBlock3Correct Attention Switching Task (AST): The difference between the median latency of response (from stimulus appearance to button press) on the trials that were congruent versus the trials that were incongruent. Median for correct trials in Block 3. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTCongruencyCostMedianBlock5Correct Attention Switching Task (AST): The difference between the median latency of response (from stimulus appearance to button press) on the trials that were congruent versus the trials that were incongruent. Median for correct trials in Block 5. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTCongruencyCostMedianBlock7Correct Attention Switching Task (AST): The difference between the median latency of response (from stimulus appearance to button press) on the trials that were congruent versus the trials that were incongruent. Median for correct trials in Block 7. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTCongruencyCostMedianCorrect Attention Switching Task (AST): The difference between the median latency of response (from stimulus appearance to button press) on the trials that were congruent versus the trials that were incongruent. Median for all correct trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTCongruencyCostSDBlock3Correct Attention Switching Task (AST): The difference between the median latency of response (from stimulus appearance to button press) on the trials that were congruent versus the trials that were incongruent. Standard deviation for correct trials in Block 3. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTCongruencyCostSDBlock5Correct Attention Switching Task (AST): The difference between the median latency of response (from stimulus appearance to button press) on the trials that were congruent versus the trials that were incongruent. Standard deviation for correct trials in Block 5. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTCongruencyCostSDBlock7Correct Attention Switching Task (AST): The difference between the median latency of response (from stimulus appearance to button press) on the trials that were congruent versus the trials that were incongruent. Standard deviation for correct trials in Block 7. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTCongruencyCostSDCorrect Attention Switching Task (AST): The difference between the median latency of response (from stimulus appearance to button press) on the trials that were congruent versus the trials that were incongruent. Standard deviation for all correct trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTMeanCorrectLatency Attention Switching Task (AST): Mean response latency on all correct trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTMeanCorrectLatencyCongruent Attention Switching Task (AST): Mean response latency on correct congruent trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTMeanCorrectLatencyDirection Attention Switching Task (AST): Mean response latency on correct direction task trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTMeanCorrectLatencyIncongruent Attention Switching Task (AST): Mean response latency on correct incongruent task trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTMeanCorrectLatencyNonSwitched Attention Switching Task (AST): Mean response latency on correct task non-switched trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTMeanCorrectLatencySide Attention Switching Task (AST): Mean response latency on correct side task trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTMeanCorrectLatencySwitched Attention Switching Task (AST): Mean response latency on correct task switched trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTMedianCorrectLatency Attention Switching Task (AST): Median response latency on all correct trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTMedianCorrectLatencyCongruent Attention Switching Task (AST): Median response latency on correct congruent trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTMedianCorrectLatencyDirection Attention Switching Task (AST): Median response latency on correct direction task trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTMedianCorrectLatencyIncongruent Attention Switching Task (AST): Median response latency on correct incongruent task trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTMedianCorrectLatencyNonSwitched Attention Switching Task (AST): Median response latency on correct task non-switched trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTMedianCorrectLatencySide Attention Switching Task (AST): Median response latency on correct side task trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTMedianCorrectLatencySwitched Attention Switching Task (AST): Median response latency on correct task switched trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTSDCorrectLatency Attention Switching Task (AST): Standard deviation of response latency on all correct trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTSDCorrectLatencyCongruent Attention Switching Task (AST): Standard deviation of response latency on correct congruent trials. Time in msec.
Outcomes.CANTABASTSDCorrectLatencyDirection Attention Switching Task (AST): Standard deviation of response latency on correct direction task trials. Time in msec.
Outcomes.CANTABASTSDCorrectLatencyIncongruent Attention Switching Task (AST): Standard deviation of response latency on correct incongruent task trials. Time in msec.
Outcomes.CANTABASTSDCorrectLatencyNonSwitched Attention Switching Task (AST): Standard deviation of response latency on correct task non-switched trials. Time in msec.
Outcomes.CANTABASTSDCorrectLatencySide Attention Switching Task (AST): Standard deviation of response latency on correct side task trials. Time in msec.
Outcomes.CANTABASTSDCorrectLatencySwitched Attention Switching Task (AST): Standard deviation of response latency on correct task switched trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTSwitchingCostMeanCorrect Attention Switching Task (AST): The difference between the median latency of response (from stimulus appearance to button press) during assessed blocks in which the rule is switching versus assessed blocks in which the rule remains constant. Mean for correct trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTSwitchingCostMeanCorrectCongruent Attention Switching Task (AST): The difference between the median latency of response (from stimulus appearance to button press) during assessed blocks in which the rule is switching versus assessed blocks in which the rule remains constant. Mean for correct congruent trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTSwitchingCostMeanCorrectIncongruent Attention Switching Task (AST): The difference between the median latency of response (from stimulus appearance to button press) during assessed blocks in which the rule is switching versus assessed blocks in which the rule remains constant. Mean for correct incongruent trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTSwitchingCostMedianCorrect Attention Switching Task (AST): The difference between the median latency of response (from stimulus appearance to button press) during assessed blocks in which the rule is switching versus assessed blocks in which the rule remains constant. Median for correct trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTSwitchingCostMedianCorrectCongruent Attention Switching Task (AST): The difference between the median latency of response (from stimulus appearance to button press) during assessed blocks in which the rule is switching versus assessed blocks in which the rule remains constant. Median for correct congruent trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTSwitchingCostMedianCorrectIncongruent Attention Switching Task (AST): The difference between the median latency of response (from stimulus appearance to button press) during assessed blocks in which the rule is switching versus assessed blocks in which the rule remains constant. Median for correct incongruent trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTSwitchingCostSDCorrect Attention Switching Task (AST): The difference between the median latency of response (from stimulus appearance to button press) during assessed blocks in which the rule is switching versus assessed blocks in which the rule remains constant. Standard deviation for correct trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTSwitchingCostSDCorrectCongruent Attention Switching Task (AST): The difference between the median latency of response (from stimulus appearance to button press) during assessed blocks in which the rule is switching versus assessed blocks in which the rule remains constant. Standard deviation for correct congruent trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTSwitchingCostSDCorrectIncongruent Attention Switching Task (AST): The difference between the median latency of response (from stimulus appearance to button press) during assessed blocks in which the rule is switching versus assessed blocks in which the rule remains constant. Standard deviation for correct incongruent trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTTestAttemptdNotCompOptions 2.7 == Not completed ­- Examinor Error
2.1 == Not completed ­- Cognitive/neurological deficits
2.2 == Not completed - Non­neurological/physical reason
2.3 == Not completed - Lack of effort/uncooperative
2.4 == Not completed -­ Language
2.5 == Not completed -­ Illness/fatigue
2.6 == Not completed ­ Logistical reasons, other reasons
Completion codes of CANTAB testings are not automatically filled in in the outcome assessment form. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTTestAttemptdNotCompOptionsOTHER Completion codes of CANTAB testings are not automatically filled in in the outcome assessment form. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTTestCompletedOptions 1.0 == Test not done
2.3 == Test attempted, but not completed
3.0 == Test completed
Completion codes of CANTAB testings are not automatically filled in in the outcome assessment form. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTTestComplNonStandAdminOTHER Completion codes of CANTAB testings are not automatically filled in in the outcome assessment form. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTTestNotDoneOptions 1.8 == Not attempted -­ Patient not available
1.1 == Not attempted -­ Cognitive/neurological deficits
1.2 == Not attempted -­ Non­neurological/physical reasons
1.3 == Not attempted -­ Lack of effort/uncooperative
1.4 == Not attempted -­ Language
1.5 == Not attempted -­ Illness/fatigue
1.6 == Not attempted -­ Logistical reasons, other reasons
1.7 == Not attempted - Return to all normal activities
For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTTestNotDoneOptionsOTHER Completion codes of CANTAB testings are not automatically filled in in the outcome assessment form. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTTotalCommissionErrors Attention Switching Task (AST): This is the total number of trials for which the trial outcome was a commission error –where the subject responded too soon; either prior to the end of the pre-empt window or prior to the appearance of the stimulus. Total errors in all blocks. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTTotalCommissionErrorsBlock3 Attention Switching Task (AST): This is the total number of trials for which the trial outcome was a commission error –where the subject responded too soon; either prior to the end of the pre-empt window or prior to the appearance of the stimulus. Total errors in block 3. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTTotalCommissionErrorsBlock5 Attention Switching Task (AST): This is the total number of trials for which the trial outcome was a commission error –where the subject responded too soon; either prior to the end of the pre-empt window or prior to the appearance of the stimulus. Total errors in block 5. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTTotalCommissionErrorsBlock7 Attention Switching Task (AST): This is the total number of trials for which the trial outcome was a commission error –where the subject responded too soon; either prior to the end of the pre-empt window or prior to the appearance of the stimulus. Total errors in block 7. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTTotalCorrectTrials Attention Switching Task (AST): This is the total number of trials which the trial outcome was a correct response. Total correct all trials. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTTotalCorrectTrialsBlock3 Attention Switching Task (AST): This is the total number of trials which the trial outcome was a correct response. Total correct Block 3. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTTotalCorrectTrialsBlock5 Attention Switching Task (AST): This is the total number of trials which the trial outcome was a correct response. Total correct Block 5. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTTotalCorrectTrialsBlock7 Attention Switching Task (AST): This is the total number of trials which the trial outcome was a correct response. Total correct Block 7. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTTotalCorrectTrialsCongruent Attention Switching Task (AST): This is the total number of trials which the trial outcome was a correct response. Total correct congruent trials. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTTotalCorrectTrialsDirection Attention Switching Task (AST): This is the total number of trials which the trial outcome was a correct response. Total correct direction trials. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTTotalCorrectTrialsIncongruent Attention Switching Task (AST): This is the total number of trials which the trial outcome was a correct response. Total correct incongruent trials. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTTotalCorrectTrialsLeftDirection Attention Switching Task (AST): This is the total number of trials which the trial outcome was a correct response. Total correct left direction trials. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTTotalCorrectTrialsLeftSide Attention Switching Task (AST): This is the total number of trials which the trial outcome was a correct response. Total correct left side trials. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTTotalCorrectTrialsNonSwitched Attention Switching Task (AST): This is the total number of trials which the trial outcome was a correct response. Total correct non-switched trials. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTTotalCorrectTrialsRightDirection Attention Switching Task (AST): This is the total number of trials which the trial outcome was a correct response. Total correct right direction trials. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTTotalCorrectTrialsRightSide Attention Switching Task (AST): This is the total number of trials which the trial outcome was a correct response. Total correct right side trials. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTTotalCorrectTrialsSide Attention Switching Task (AST): This is the total number of trials which the trial outcome was a correct response. Total correct side trials. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTTotalCorrectTrialsSwitched Attention Switching Task (AST): This is the total number of trials which the trial outcome was a correct response. Total correct switched trials. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTTotalIncorrectTrials Attention Switching Task (AST): This is the total number of trials which the trial outcome was an incorrect response. Total incorrect all trials. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTTotalIncorrectTrialsBlock3 Attention Switching Task (AST): This is the total number of trials which the trial outcome was an incorrect response. Total incorrect Block 3. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTTotalIncorrectTrialsBlock5 Attention Switching Task (AST): This is the total number of trials which the trial outcome was an incorrect response. Total incorrect Block 5. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTTotalIncorrectTrialsBlock7 Attention Switching Task (AST): This is the total number of trials which the trial outcome was an incorrect response. Total incorrect Block 7. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTTotalIncorrectTrialsCongruent Attention Switching Task (AST): This is the total number of trials which the trial outcome was an incorrect response. Total incorrect congruent trials. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTTotalIncorrectTrialsDirection Attention Switching Task (AST): This is the total number of trials which the trial outcome was an incorrect response. Total incorrect direction trials. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTTotalIncorrectTrialsIncongruent Attention Switching Task (AST): This is the total number of trials which the trial outcome was an incorrect response. Total incorrect incongruent trials. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTTotalIncorrectTrialsLeftDirection Attention Switching Task (AST): This is the total number of trials which the trial outcome was an incorrect response. Total incorrect left direction trials. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTTotalIncorrectTrialsLeftSide Attention Switching Task (AST): This is the total number of trials which the trial outcome was an incorrect response. Total incorrect left side trials. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTTotalIncorrectTrialsNonSwitched Attention Switching Task (AST): This is the total number of trials which the trial outcome was an incorrect response. Total incorrect non-switched trials. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTTotalIncorrectTrialsRightDirection Attention Switching Task (AST): This is the total number of trials which the trial outcome was an incorrect response. Total incorrect right direction trials. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTTotalIncorrectTrialsRightSide Attention Switching Task (AST): This is the total number of trials which the trial outcome was an incorrect response. Total incorrect right side trials. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTTotalIncorrectTrialsSide Attention Switching Task (AST): This is the total number of trials which the trial outcome was an incorrect response. Total incorrect side trials. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTTotalIncorrectTrialsSwitched Attention Switching Task (AST): This is the total number of trials which the trial outcome was an incorrect response. Total incorrect switched trials. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTTotalOmissionErrors Attention Switching Task (AST): This is the total number of This is the total number of trials, for which the trial outcome was an omission error which the trial outcome was an omission error – where the subject responded too late, after end where the subject responded too late, after end of the response window. Total errors all trials. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTTotalOmissionErrorsBlock3 Attention Switching Task (AST): This is the total number of This is the total number of trials, for which the trial outcome was an omission error which the trial outcome was an omission error – where the subject responded too late, after end where the subject responded too late, after end of the response window. Total errors Block 3. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTTotalOmissionErrorsBlock5 Attention Switching Task (AST): This is the total number of This is the total number of trials, for which the trial outcome was an omission error which the trial outcome was an omission error – where the subject responded too late, after end where the subject responded too late, after end of the response window. Total errors Block 5 For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABASTTotalOmissionErrorsBlock7 Attention Switching Task (AST): This is the total number of This is the total number of trials, for which the trial outcome was an omission error which the trial outcome was an omission error – where the subject responded too late, after end where the subject responded too late, after end of the response window. Total errors Block 7 For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABBattery Test battery used. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABDaysPost Test session days post-injury For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABPAL 1.0 == 1.0 Test completed in full
1.1 == 1.1 Non-standard adm - written
1.2 == 1.2 Non-standard adm - other
1.3 == 1.3 Test completed over the phone
2.1 == 2.1 Not completed - Cognitive/neuro
2.2 == 2.2 Not completed - Non-neuro/phys
2.3 == 2.3 Not completed - Poor effort
2.4 == 2.4 Not completed - Language
2.5 == 2.5 Not completed - Illness
2.6 == 2.6 Not completed - Logistical
3.1 == 3.1 Not attempted - Cognitive/neuro
3.2 == 3.2 Not attempted - Non-neuro/phys
3.3 == 3.3 Not attempted - Poor effort
3.4 == 3.4 Not attempted - Language
3.5 == 3.5 Not attempted - Illness
3.6 == 3.6 Not attempted - Logistical
4.0 == 4.0 Not attempted - Examiner error
5.0 == 5.0 Not attempted - Other
For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABPALCompCode 1.0 == 1.0 Test not done
2.0 == 2.0 Test attempted but not completed
3.0 == 3.0 Test completed
For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABPALFirstTrialMemoryScore Paired Associate Learning (PAL): The number of correct box choices that were made on the first attempt during assessment problems For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABPALMeanErrorsToSuccess Paired Associate Learning (PAL): This measure summarises, for all stages, the mean number of errors made before the stage was successfully completed. It is calculated by summing the total errors for all attempted stages and dividing the result by the number of successfully completed stages. Lower is better. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABPALMeanTrialsToSuccess Paired Associate Learning (PAL): This is calculated by calculating the total number of trials required (maximum score=10 trials per stage) to locate all the patterns correctly in all stages attempted, and dividing the result by the number of successfully completed stages. Lower is better. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABPALNumberOfPatternsReached Paired Associate Learning (PAL): This is calculated by calculating the total number of trials required (maximum score=10 trials per stage) to locate all the patterns correctly in all stages attempted, and dividing the result by the number of successfully completed stages. Lower is better. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABPALStagesCompleted Paired Associate Learning (PAL): This is a key indicator of the subject’s overall success, recording how many stages were successfully completed. When analysing other outcome measures from PAL it is crucial that analyses are conducted with reference to the number of stages completed. Clearly a subject that fails prior to the successful completion of the 8-pattern stage will have had less opportunity to make errors than a subject who completes the test. Higher is better. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABPALStagesCompletedOnFirstTrial Paired Associate Learning (PAL): This is the number of stages passed on the first trial (out of a maximum of 8 stages in the clinical mode). This relates to the PAL first trial memory score. Higher is better. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABPALTestAttemptdNotCompOptions 2.7 == Not completed ­- Examinor Error
2.1 == Not completed ­- Cognitive/neurological deficits
2.2 == Not completed - Non­neurological/physical reason
2.3 == Not completed - Lack of effort/uncooperative
2.4 == Not completed -­ Language
2.5 == Not completed -­ Illness/fatigue
2.6 == Not completed ­ Logistical reasons, other reasons
Completion codes of CANTAB testings are not automatically filled in in the outcome assessment form. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABPALTestAttemptdNotCompOptionsOTHER Completion codes of CANTAB testings are not automatically filled in in the outcome assessment form. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABPALTestCompletedOptions 3.0 == Test completed in full - results valid
3.1 == Test completed - Non-standard, results valid
3.2 == Non-standard administration - Other
Completion codes of CANTAB testings are not automatically filled in in the outcome assessment form. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABPALTestComplNonStandAdminOTHER Completion codes of CANTAB testings are not automatically filled in in the outcome assessment form. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABPALTestNotDoneOptions 1.8 == Not attempted -­ Patient not available
1.1 == Not attempted -­ Cognitive/neurological deficits
1.2 == Not attempted -­ Non­neurological/physical reasons
1.3 == Not attempted -­ Lack of effort/uncooperative
1.4 == Not attempted -­ Language
1.5 == Not attempted -­ Illness/fatigue
1.6 == Not attempted -­ Logistical reasons, other reasons
1.7 == Not attempted - Return to all normal activities
Completion codes of CANTAB testings are not automatically filled in in the outcome assessment form. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABPALTestNotDoneOptionsOTHER Completion codes of CANTAB testings are not automatically filled in in the outcome assessment form. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABPALTotalErrors Paired Associate Learning (PAL): This measure reports the total number of errors across all assessed problems and all stages. Note that subjects failing at any stage of the test have had less opportunity to make errors than subjects who complete the test. The PAL Total errors (adjusted) measure attempts to compensate for this. Lower is better. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABPALTotalErrors2Shapes Paired Associate Learning (PAL): Total errors on 2-pattern trials For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABPALTotalErrors2ShapesAdjusted Paired Associate Learning (PAL): This measure reports the total number of errors made at the two 2-pattern stages (when there is a stimulus in two of the 6 boxes), with an adjustment for those who have not reached these stages. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABPALTotalErrors3Shapes Paired Associate Learning (PAL): Total errors on 3-pattern trials For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABPALTotalErrors3ShapesAdjusted Paired Associate Learning (PAL): This measure reports the total number of errors made at the two 3-pattern stages (when there is a stimulus in three of the 6 boxes), with an adjustment for those who have not reached these stages. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABPALTotalErrors6Shapes Paired Associate Learning (PAL): Total errors on 6-pattern trials For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABPALTotalErrors6ShapesAdjusted Paired Associate Learning (PAL): This measure reports the total number of errors made at the 6 -pattern stage (when there is a stimulus in each the 6 boxes), with an adjustment for those who have not reached these stage. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABPALTotalErrors8Shapes Paired Associate Learning (PAL): Total errors on 8-pattern trials For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABPALTotalErrors8ShapesAdjusted Paired Associate Learning (PAL): This measure reports the total number of errors made at the 8-pattern stage (when there is a stimulus in each the 8 boxes), with an adjustment for those who have not reached these stage.
Outcomes.CANTABPALTotalErrorsAdjusted Paired Associate Learning (PAL): This measure reports the total number of errors across all assessed problems and all stages, with an adjustment for each stage not attempted due to previous failure.
Outcomes.CANTABPALTotalTrials Paired Associate Learning (PAL): This measure represents the total number of trials required.
Outcomes.CANTABPALTotalTrials2Shapes Paired Associate Learning (PAL): This measure represents the number of trials required at the 2-pattern stage.
Outcomes.CANTABPALTotalTrials3Shapes Paired Associate Learning (PAL): This measure represents the number of trials required at the 3-pattern stage.
Outcomes.CANTABPALTotalTrials6Shapes Paired Associate Learning (PAL): This measure represents the number of trials required at the 6-pattern stage.
Outcomes.CANTABPALTotalTrials8Shapes Paired Associate Learning (PAL): This measure represents the number of trials required at the 8-pattern stage.
Outcomes.CANTABPALTotalTrialsAdjusted Paired Associate Learning (PAL): This measure represents the total number of presentations required to locate all the patterns correctly in all stages. When using this measure it is important to analyse the data with reference to the PAL Stages completed score. This is because subjects who fail to complete the test will have had fewer PAL Total trials simply because they had less opportunity to make errors than subjects who completed the test. One possible way of dealing with this is to add the maximum score of 10 trials (or 6, depending on the mode) for each stage not attempted due to an earlier failure and this is what this measure shows. Please note that if this adjustment is made to a dataset in which large numbers of subjects have failed, this will have the effect of markedly reducing variance in later stages. Note that for aborted runs, the adjustment is made based on the subject failing the stage on which the test was aborted, so each of the 10 trials(or 6, depending on the mode) from that stage will count as part of the adjusted score. Lower is better. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABRTI 1.0 == 1.0 Test completed in full
1.1 == 1.1 Non-standard adm - written
1.2 == 1.2 Non-standard adm - other
1.3 == 1.3 Test completed over the phone
2.1 == 2.1 Not completed - Cognitive/neuro
2.2 == 2.2 Not completed - Non-neuro/phys
2.3 == 2.3 Not completed - Poor effort
2.4 == 2.4 Not completed - Language
2.5 == 2.5 Not completed - Illness
2.6 == 2.6 Not completed - Logistical
3.1 == 3.1 Not attempted - Cognitive/neuro
3.2 == 3.2 Not attempted - Non-neuro/phys
3.3 == 3.3 Not attempted - Poor effort
3.4 == 3.4 Not attempted - Language
3.5 == 3.5 Not attempted - Illness
3.6 == 3.6 Not attempted - Logistical
4.0 == 4.0 Not attempted - Examiner error
5.0 == 5.0 Not attempted - Other
For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABRTICompCode 1.0 == Test not done
2.0 == Test attempted but not completed
3.0 == Test completed
For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABRTIFiveChoiceErrorScoreAll Reaction time (RTI): This is the total number of trials where the response status is recorded as an error, for assessment trials where the stimuli appear in one of five locations. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABRTIFiveChoiceErrorScoreInaccurate Reaction time (RTI): This is the total number of trials where the response status is recorded as the specified error type, for assessment trials where the stimuli appear in one of five locations. Error types: inaccurate, incorrect location, premature, or no response settings. Lower is better. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABRTIFiveChoiceErrorScoreIncorrectLocation Reaction time (RTI): This is the total number of trials where the response status is recorded as the specified error type, for assessment trials where the stimuli appear in one of five locations. Error types: inaccurate, incorrect location, premature, or no response settings. Lower is better. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABRTIFiveChoiceErrorScoreNoResponse Reaction time (RTI): This is the total number of trials where the response status is recorded as the specified error type, for assessment trials where the stimuli appear in one of five locations. Error types: inaccurate, incorrect location, premature, or no response settings. Lower is better. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABRTIFiveChoiceErrorScorePremature Reaction time (RTI): This is the total number of trials where the response status is recorded as the specified error type, for assessment trials where the stimuli appear in one of five locations. Error types: inaccurate, incorrect location, premature, or no response settings. Lower is better. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABRTIMeanFiveChoiceMovementTime Reaction time (RTI): This is the time taken to touch the stimulus after the press pad button has been released in trials where the stimulus has been presented in one of five possible locations. Lower is better. Mean for correct trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABRTIMeanFiveChoiceReactionTime Reaction time (RTI): This is the speed with which the subject releases the press pad button in response to a stimulus in any one of five locations. Mean for correct trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABRTIMeanSimpleMovementTime Reaction time (RTI): This is the time taken to touch the stimulus after the press pad button has been released in trials where the stimulus has been presented in one location. Lower is better. Mean for correct trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABRTIMeanSimpleReactionTime Reaction time (RTI): This is the speed with which the subject releases the press pad button in response to a stimulus in one location. Mean for correct trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABRTIMedianFiveChoiceMovementTime Reaction time (RTI): This is the time taken to touch the stimulus after the press pad button has been released in trials where the stimulus has been presented in one of five possible locations. Lower is better. Median for correct congruent trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABRTIMedianFiveChoiceReactionTime Reaction time (RTI): This is the speed with which the subject releases the press pad button in response to a stimulus in any one of five locations. Median for correct incongruent trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABRTIMedianSimpleMovementTime Reaction time (RTI): This is the time taken to touch the stimulus after the press pad button has been released in trials where the stimulus has been presented in one location. Lower is better. Median for correct congruent trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABRTIMedianSimpleReactionTime Reaction time (RTI): This is the speed with which the subject releases the press pad button in response to a stimulus in one location. Median for correct incongruent trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABRTISDFiveChoiceMovementTime Reaction time (RTI): This is the time taken to touch the stimulus after the press pad button has been released in trials where the stimulus has been presented in one of five possible locations. Lower is better. Standard deviation for correct trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABRTISDFiveChoiceReactionTime Reaction time (RTI): This is the speed with which the subject releases the press pad button in response to a stimulus in any one of five locations. Standard deviation for correct congruent trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABRTISDSimpleMovementTime Reaction time (RTI): This is the time taken to touch the stimulus after the press pad button has been released in trials where the stimulus has been presented in one location. Lower is better. Standard deviation for correct trials. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABRTISDSimpleReactionTime Reaction time (RTI): This is the speed with which the subject releases the press pad button in response to a stimulus in one location. Standard deviation for correct congruent trials. Time in msec.
Outcomes.CANTABRTISimpleAccuracyScore Reaction time (RTI): This is the total number of trials where the response is recorded as correct, for assessment trials where the stimuli appear in one location only. Higher is better. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABRTITestAttemptdNotCompOptions 2.7 == Not completed ­- Examinor Error
2.1 == Not completed ­- Cognitive/neurological deficits
2.2 == Not completed - Non­neurological/physical reason
2.3 == Not completed - Lack of effort/uncooperative
2.4 == Not completed -­ Language
2.5 == Not completed -­ Illness/fatigue
2.6 == Not completed ­ Logistical reasons, other reasons
Completion codes of CANTAB testings are not automatically filled in in the outcome assessment form. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABRTITestAttemptdNotCompOptionsOTHER For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABRTITestCompletedOptions 3.0 == Test completed in full - results valid
3.1 == Test completed - Non-standard, results valid
3.2 == Non-standard administration - Other
Completion codes of CANTAB testings are not automatically filled in in the outcome assessment form. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABRTITestComplNonStandAdminOTHER For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABRTITestNotDoneOptions 1.8 == Not attempted -­ Patient not available
1.1 == Not attempted -­ Cognitive/neurological deficits
1.2 == Not attempted -­ Non­neurological/physical reasons
1.3 == Not attempted -­ Lack of effort/uncooperative
1.4 == Not attempted -­ Language
1.5 == Not attempted -­ Illness/fatigue
1.6 == Not attempted -­ Logistical reasons, other reasons
1.7 == Not attempted - Return to all normal activities
For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABRTITestNotDoneOptionsOTHER For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABRVP 1.0 == 1.0 Test completed in full
1.1 == 1.1 Non-standard adm - written
1.2 == 1.2 Non-standard adm - other
1.3 == 1.3 Test completed over the phone
2.1 == 2.1 Not completed - Cognitive/neuro
2.2 == 2.2 Not completed - Non-neuro/phys
2.3 == 2.3 Not completed - Poor effort
2.4 == 2.4 Not completed - Language
2.5 == 2.5 Not completed - Illness
2.6 == 2.6 Not completed - Logistical
3.1 == 3.1 Not attempted - Cognitive/neuro
3.2 == 3.2 Not attempted - Non-neuro/phys
3.3 == 3.3 Not attempted - Poor effort
3.4 == 3.4 Not attempted - Language
3.5 == 3.5 Not attempted - Illness
3.6 == 3.6 Not attempted - Logistical
4.0 == 4.0 Not attempted - Examiner error
5.0 == 5.0 Not attempted - Other
For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABRVPA Rapid Visual Information Processing (RVP): A′ (A prime) is the signal detection measure of sensitivity to the target, regardless of response tendency (range 0.00 to 1.00; bad to good). In essence, this measure is a measure of how good the subject is at detectingtarget sequences using p(hit) and p(fa). For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABRVPB Rapid Visual Information Processing (RVP): B″ (B double prime) is the signal detection measure of the strength of trace required to elicit a response (range –1.00 to +1.00). Thus, it is the tendency to respond regardless of whether the target sequence is present, and uses the p(hit) and p(fa) results. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABRVPCompCode 1.0 == Test not done
2.0 == Test attempted but not completed
3.0 == Test completed
For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABRVPMeanLatency Rapid Visual Information Processing (RVP): This measure details the mean time taken to respond and is reported in milliseconds. It only includes correct responses made within the response window of 1800 milliseconds. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABRVPMedianLatency Rapid Visual Information Processing (RVP): This measure details the median time taken to respond and is reported in milliseconds. It only includes correct responses made within the response window of 1800 milliseconds. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABRVPProbabilityOfFalseAlarm Rapid Visual Information Processing (RVP): The probability of a false alarm or p(fa) (the subject responding inappropriately), is equal to total false alarms/(total false alarms + total correct rejections). For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABRVPProbabilityOfHit Rapid Visual Information Processing (RVP): The probability of a ‘hit’ or p(hit), (the subject responding correctly), is calculated from hits/(hits+misses). For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABRVPSDLatency Rapid Visual Information Processing (RVP): This measure details the standard deviation of the time taken to respond and is reported in milliseconds. It only includes correct responses made within the response window of 1800 milliseconds. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABRVPTestAttemptdNotCompOptions 2.7 == Not completed ­- Examiner error
2.1 == Not completed -­ Cognitive/neurological deficits
2.2 == Not completed -­ Non­neurological/physical reason
2.3 == Not completed -­ Lack of effort/uncooperative
2.4 == Not completed -­ Language
2.5 == Not completed -­ Illness/fatigue
2.6 == Not completed -­ Logistical reasons, other reasons
For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABRVPTestAttemptdNotCompOptionsOTHER For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABRVPTestCompletedOptions 3.0 == Test completed in full - results valid
3.1 == Test completed - Non-standard, results valid
3.2 == Non-standard administration - Other
For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABRVPTestComplNonStandAdminOTHER For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABRVPTestNotDoneOptions 1.8 == Not attempted -­ Patient not available
1.1 == Not attempted -­ Cognitive/neurological deficits
1.2 == Not attempted -­ Non­neurological/physical reasons
1.3 == Not attempted -­ Lack of effort/uncooperative
1.4 == Not attempted -­ Language
1.5 == Not attempted -­ Illness/fatigue
1.6 == Not attempted -­ Logistical reasons, other reasons
1.7 == Not attempted - Return to all normal activities
For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABRVPTestNotDoneOptionsOTHER
Outcomes.CANTABRVPTotalCorrectRejections Rapid Visual Information Processing (RVP): This is the number of stimuli that were correctly rejected, i.e., the number of stimuli that were not part of a target sequence and were not responded to. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABRVPTotalFalseAlarms Rapid Visual Information Processing (RVP): This records the number of times the subject responds outside the response window of a target sequence. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABRVPTotalHits Rapid Visual Information Processing (RVP): This score represents the number of occasions upon which the target sequence is correctly responded to. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABRVPTotalMisses Rapid Visual Information Processing (RVP): This score reports the number of occasions the subject fails to respond to a target sequence within the response window For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSessionStartDate Session test date For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSOCCompCode 1.0 == Test not done
2.0 == Test attempted but not completed
3.0 == Test completed
For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSOCMeanInitialThinkingTime2Moves Stockings of Cambridge (SOC): Outcome only available when tested in clinical mode. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSOCMeanInitialThinkingTime3Moves Stockings of Cambridge (SOC): Outcome only available when tested in clinical mode. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSOCMeanInitialThinkingTime4Moves Stockings of Cambridge (SOC): Outcome only available when tested in clinical mode. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSOCMeanInitialThinkingTime5Moves Stockings of Cambridge (SOC): Outcome only available when tested in clinical mode. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSOCMeanMoves2Moves Stockings of Cambridge (SOC): Outcome only available when tested in clinical mode. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSOCMeanMoves3Moves Stockings of Cambridge (SOC): Outcome only available when tested in clinical mode. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSOCMeanMoves4Moves Stockings of Cambridge (SOC): Outcome only available when tested in clinical mode. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSOCMeanMoves5Moves Stockings of Cambridge (SOC): Outcome only available when tested in clinical mode. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSOCMeanSubsequentThinkingTime2Moves Stockings of Cambridge (SOC): Outcome only available when tested in clinical mode. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSOCMeanSubsequentThinkingTime3Moves Stockings of Cambridge (SOC): Outcome only available when tested in clinical mode. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSOCMeanSubsequentThinkingTime4Moves Stockings of Cambridge (SOC): Outcome only available when tested in clinical mode. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSOCMeanSubsequentThinkingTime5Moves Stockings of Cambridge (SOC): Outcome only available when tested in clinical mode. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSOCProblemsSolvedInMinimumMoves Stockings of Cambridge (SOC): This is a fundamental measure, recording the number of occasions upon which the subject has successfully completed a test problem in the minimum possible number of moves. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSOCProblemsSolvedInMinimumMoves2Moves Stockings of Cambridge (SOC): Describes the mean number of moves required by the subject to solve problems where the solution can be reached in a minimum of 2 moves. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSOCProblemsSolvedInMinimumMoves3Moves Stockings of Cambridge (SOC): Describes the mean number of moves required by the subject to solve problems where the solution can be reached in a minimum of 3 moves. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSOCProblemsSolvedInMinimumMoves4Moves Stockings of Cambridge (SOC): Describes the mean number of moves required by the subject to solve problems where the solution can be reached in a minimum of 4 moves. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSOCProblemsSolvedInMinimumMoves5Moves Stockings of Cambridge (SOC): Describes the mean number of moves required by the subject to solve problems where the solution can be reached in a minimum of 5 moves. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSOCTestAttemptdNotCompOptions 2.7 == Not completed ­- Examiner error
2.1 == Not completed -­ Cognitive/neurological deficits
2.2 == Not completed -­ Non­neurological/physical reason
2.3 == Not completed -­ Lack of effort/uncooperative
2.4 == Not completed -­ Language
2.5 == Not completed -­ Illness/fatigue
2.6 == Not completed -­ Logistical reasons, other reasons
For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSOCTestAttemptdNotCompOptionsOTHER For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSOCTestCompletedOptions 3.0 == Test completed in full - results valid
3.1 == Test completed - Non-standard, results valid
3.2 == Non-standard administration - Other
For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSOCTestComplNonStandAdminOTHER For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSOCTestNotDoneOptions 1.8 == Not attempted -­ Patient not available
1.1 == Not attempted -­ Cognitive/neurological deficits
1.2 == Not attempted -­ Non­neurological/physical reasons
1.3 == Not attempted -­ Lack of effort/uncooperative
1.4 == Not attempted -­ Language
1.5 == Not attempted -­ Illness/fatigue
1.6 == Not attempted -­ Logistical reasons, other reasons
1.7 == Not attempted - Return to all normal activities
For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSOCTestNotDoneOptionsOTHER For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABStockingsOfCambridge 1.0 == 1.0 Test completed in full
1.1 == 1.1 Non-standard adm - written
1.2 == 1.2 Non-standard adm - other
1.3 == 1.3 Test completed over the phone
2.1 == 2.1 Not completed - Cognitive/neuro
2.2 == 2.2 Not completed - Non-neuro/phys
2.3 == 2.3 Not completed - Poor effort
2.4 == 2.4 Not completed - Language
2.5 == 2.5 Not completed - Illness
2.6 == 2.6 Not completed - Logistical
3.1 == 3.1 Not attempted - Cognitive/neuro
3.2 == 3.2 Not attempted - Non-neuro/phys
3.3 == 3.3 Not attempted - Poor effort
3.4 == 3.4 Not attempted - Language
3.5 == 3.5 Not attempted - Illness
3.6 == 3.6 Not attempted - Logistical
4.0 == 4.0 Not attempted - Examiner error
5.0 == 5.0 Not attempted - Other
For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWM 1.0 == 1.0 Test completed in full
1.1 == 1.1 Non-standard adm - written
1.2 == 1.2 Non-standard adm - other
1.3 == 1.3 Test completed over the phone
2.1 == 2.1 Not completed - Cognitive/neuro
2.2 == 2.2 Not completed - Non-neuro/phys
2.3 == 2.3 Not completed - Poor effort
2.4 == 2.4 Not completed - Language
2.5 == 2.5 Not completed - Illness
2.6 == 2.6 Not completed - Logistical
3.1 == 3.1 Not attempted - Cognitive/neuro
3.2 == 3.2 Not attempted - Non-neuro/phys
3.3 == 3.3 Not attempted - Poor effort
3.4 == 3.4 Not attempted - Language
3.5 == 3.5 Not attempted - Illness
3.6 == 3.6 Not attempted - Logistical
4.0 == 4.0 Not attempted - Examiner error
5.0 == 5.0 Not attempted - Other
For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMBetweenErrors Spatial Working Memory (SWM): Between errors are defined as times the subject revisits a box in which a token has previously been found. This is calculated for all trials of four or more tokens only. Lower is better. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMBetweenErrors4Boxes Spatial Working Memory (SWM): Between errors are defined as times the subject revisits a box in which a token has previously been found. This is calculated for trials of four tokens only. Lower is better. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMBetweenErrors6Boxes Spatial Working Memory (SWM): Between errors are defined as times the subject revisits a box in which a token has previously been found. This is calculated for trials of six tokens only. Lower is better. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMBetweenErrors8Boxes Spatial Working Memory (SWM): Between errors are defined as times the subject revisits a box in which a token has previously been found. This is calculated for trials of eight tokens only. Lower is better. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMCompCode 1.0 == Test not done
2.0 == Test attempted but not completed
3.0 == Test completed
For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMMeanTimeToFirstResponse Spatial Working Memory (SWM): This is the mean time between the problem being presented to the subject and the subject first touching the screen to open a box. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMMeanTimeToFirstResponse4Boxes Spatial Working Memory (SWM): This is the mean time between the problem being presented to the subject and the subject first touching the screen to open a box, for problems with 4 boxes. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMMeanTimeToFirstResponse6Boxes Spatial Working Memory (SWM): This is the mean time between the problem being presented to the subject and the subject first touching the screen to open a box, for problems with 6 boxes. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMMeanTimeToFirstResponse8Boxes Spatial Working Memory (SWM): This is the mean time between the problem being presented to the subject and the subject first touching the screen to open a box, for problems with 8 boxes. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMMeanTimeToLastResponse Spatial Working Memory (SWM): This is the mean time for the subject’s last response for a problem. Time in msec. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMMeanTimeToLastResponse4Boxes For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMMeanTimeToLastResponse6Boxes For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMMeanTimeToLastResponse8Boxes For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMMeanTokenSearchPreparationTime For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMMeanTokenSearchPreparationTime4Boxes For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMMeanTokenSearchPreparationTime6Boxes For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMMeanTokenSearchPreparationTime8Boxes For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMMedianTimeToFirstResponse For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMMedianTimeToFirstResponse4Boxes For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMMedianTimeToFirstResponse6Boxes For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMMedianTimeToFirstResponse8Boxes For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMMedianTimeToLastResponse For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMMedianTimeToLastResponse4Boxes For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMMedianTimeToLastResponse6Boxes For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMMedianTimeToLastResponse8Boxes For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMMedianTokenSearchPreparationTime For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMMedianTokenSearchPreparationTime4Boxes For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMMedianTokenSearchPreparationTime6Boxes For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMMedianTokenSearchPreparationTime8Boxes For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMProblemReached For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMSDTimeToFirstResponse For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMSDTimeToFirstResponse4Boxes For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMSDTimeToFirstResponse6Boxes For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMSDTimeToFirstResponse8Boxes For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMSDTimeToLastResponse For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMSDTimeToLastResponse4Boxes For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMSDTimeToLastResponse6Boxes For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMSDTimeToLastResponse8Boxes For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMSDTokenSearchPreparationTime For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMSDTokenSearchPreparationTime4Boxes For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMSDTokenSearchPreparationTime6Boxes For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMSDTokenSearchPreparationTime8Boxes For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMStrategy For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMStrategy6To8Boxes For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMTestAttemptdNotCompOptions 2.7 == Not completed ­- Examiner error
2.1 == Not completed -­ Cognitive/neurological deficits
2.2 == Not completed -­ Non­neurological/physical reason
2.3 == Not completed -­ Lack of effort/uncooperative
2.4 == Not completed -­ Language
2.5 == Not completed -­ Illness/fatigue
2.6 == Not completed -­ Logistical reasons, other reasons
For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMTestAttemptdNotCompOptionsOTHER For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMTestCompletedOptions 3.0 == Test completed in full - results valid
3.1 == Test completed - Non-standard, results valid
3.2 == Non-standard administration - Other
Completion codes of CANTAB testings are not automatically filled in in the outcome assessment form. For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMTestComplNonStandAdminOTHER For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMTestNotDoneOptions 1.8 == Not attempted -­ Patient not available
1.1 == Not attempted -­ Cognitive/neurological deficits
1.2 == Not attempted -­ Non­neurological/physical reasons
1.3 == Not attempted -­ Lack of effort/uncooperative
1.4 == Not attempted -­ Language
1.5 == Not attempted -­ Illness/fatigue
1.6 == Not attempted -­ Logistical reasons, other reasons
1.7 == Not attempted - Return to all normal activities
For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABSWMTestNotDoneOptionsOTHER For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.CANTABTestingLanguage For more detailed information on CANTAB outcome measures, we strongly recommend to check the User Manual -Appendix 3!
Outcomes.DerivedCompositeGOSE 1 == 1-Dead
3 == 2 / 3- Vegetative State (VS) / Lower Severe Disability (Lower SD)
4 == 4-Upper Severe Disability (Upper SD)
5 == 5-Lower Moderate Disability (Lower MD)
6 == 6-Upper Moderate Disability (Upper MD)
7 == 7-Lower Good Recovery (Lower GR)
8 == 8-Upper Good Recovery (Upper GR)
This GOSE rating is a derived composite score based on central review. The categories of Vegetative State and Lower Severe Disability are collapsed in the ratings assigned. Available information is used in the following order of precedence for the composite: (1) Central scoring of GOSE interview questionnaires completed by investigators (2) Central scoring based on GOSE postal questionnaires completed by patients and carers (3) Interviewer ratings for survivors, when neither of the GOSE questionnaires have been completed. (4) Deaths recorded in the eCRF where the date of death is on or before the end of the window for follow-up.
Outcomes.DerivedCompositeGOSEDaysPostInjury Days post-injury for composite GOSE assessment calculated from the date recorded for the corresponding interview or self-report questionnaire. A date is only included for ratings in survivors (i.e Outcomes.DerivedCompositeGOSE >1).
Outcomes.Derived_SF12ScoreBP
Outcomes.Derived_SF12ScoreBPNBS
Outcomes.Derived_SF12ScoreGH
Outcomes.Derived_SF12ScoreGHNBS
Outcomes.Derived_SF12ScoreHMNBS
Outcomes.Derived_SF12ScoreMCS Derived variable (i.e. SF-12 scores derived from SF-36 questionnaires).
Outcomes.Derived_SF12ScoreMH
Outcomes.Derived_SF12ScorePCS Derived variable (i.e. SF-12 scores derived from SF-36 questionnaires).
Outcomes.Derived_SF12ScorePF
Outcomes.Derived_SF12ScorePFNBS
Outcomes.Derived_SF12ScoreRE
Outcomes.Derived_SF12ScoreRENBS
Outcomes.Derived_SF12ScoreRP
Outcomes.Derived_SF12ScoreRPNBS
Outcomes.Derived_SF12ScoreSF
Outcomes.Derived_SF12ScoreSFNBS
Outcomes.Derived_SF12ScoreVT
Outcomes.Derived_SF12ScoreVTNBS
Outcomes.GAD7Afraid 0 == 0 - Not at all
1 == 1 - Several days
2 == 2 - More than half the days
3 == 3 - Nearly every day
Outcomes.GAD7Annoyed 0 == 0 - Not at all
1 == 1 - Several days
2 == 2 - More than half the days
3 == 3 - Nearly every day
Outcomes.GAD7Date
Outcomes.GAD7Nervous 0 == 0 - Not at all
1 == 1 - Several days
2 == 2 - More than half the days
3 == 3 - Nearly every day
Outcomes.GAD7NonStopWorry 0 == 0 - Not at all
1 == 1 - Several days
2 == 2 - More than half the days
3 == 3 - Nearly every day
Outcomes.GAD7Performed 0 == Not performed
1 == Performed/Completed
Responses for the GAD-7 relate to how oftent the subject has been bothered in the last 2 weeks
Outcomes.GAD7QuestionnaireMode 1 == Telephone interview
2 == Postal questionnaire
3 == Web-based completion
4 == Personal interview
Outcomes.GAD7Restless 0 == 0 - Not at all
1 == 1 - Several days
2 == 2 - More than half the days
3 == 3 - Nearly every day
Outcomes.GAD7TotalScore Not scored by investigator, calculated score.
Outcomes.GAD7TrblRelax 0 == 0 - Not at all
1 == 1 - Several days
2 == 2 - More than half the days
3 == 3 - Nearly every day
Outcomes.GAD7WorryTooMuch 0 == 0 - Not at all
1 == 1 - Several days
2 == 2 - More than half the days
3 == 3 - Nearly every day
Outcomes.GOATBrnDate -4 == Error (-4)
0 == No Error
Outcomes.GOATBuldngLoc -5 == Error (-5)
0 == No Error
Outcomes.GOATCityLoc -5 == Error (-5)
0 == No Error
Outcomes.GOATCompletionCode 1.0 == 1.0 Test completed in full
1.1 == 1.1 Non-standard adm - written
1.2 == 1.2 Non-standard adm - other
1.3 == 1.3 Test completed over the phone
2.1 == 2.1 Not completed - Cognitive/neuro
2.2 == 2.2 Not completed - Non-neuro/phys
2.3 == 2.3 Not completed - Poor effort
2.4 == 2.4 Not completed - Language
2.5 == 2.5 Not completed - Illness
2.6 == 2.6 Not completed - Logistical
3.1 == 3.1 Not attempted - Cognitive/neuro
3.2 == 3.2 Not attempted - Non-neuro/phys
3.3 == 3.3 Not attempted - Poor effort
3.4 == 3.4 Not attempted - Language
3.5 == 3.5 Not attempted - Illness
3.6 == 3.6 Not attempted - Logistical
4.0 == 4.0 Not attempted - Examiner error
5.0 == 5.0 Not attempted - Other
Neuropsych testing was scheduled for all scheduled follow-up visits according to study protocol. Subjects were only considered testable if the GOAT was >=65. Neuropsych testing included: GOAT, RAVLT, TMT, CANTAB subtests, 10 m walk, Timed up-and-go, as well as Participant Questionnaire B.. "Untestable" patients received the GOAT and JFK-Coma Recovery Scale-revised.
Outcomes.GOATCrntTm -5 == Two and one-half hour + error (-5)
-4 == Two hour error (-4)
-3 == One and one-half hour error (-3)
-2 == One hour error (-2)
-1 == Half-hour error (-1)
0 == No Error
Outcomes.GOATDate Assessment of the GOAT was requested on discharge from the ER for all subjects who had regained consciousness and were able to undergo the test. A main research interest was to explore if - and how many - patients were still in PTA on discharge home. Patients are considered out of PTA if they have a total score of 78 or more.
Outcomes.GOATDayDate -3 == Three day error (-3)
-2 == Two day error (-2)
-1 == One day error (-1)
0 == No Error
Outcomes.GOATDayMnthDate -5 == Five day + error (-5)
-4 == Four day error (-4)
-3 == Three day error (-3)
-2 == Two day error (-2)
-1 == One day error (-1)
0 == No Error
Outcomes.GOATDtlRslt -5 == Error (-5)
0 == No Error
Outcomes.GOATFirEvntRslt -5 == Error (-5)
0 == No Error
Outcomes.GOATFirEvntRsltTxt
Outcomes.GOATHospAdmDate -5 == Error (-5)
0 == No Error
Outcomes.GOATLiveLoc -4 == Error (-4)
0 == No Error
Outcomes.GOATLstEvntDtlRslt -5 == Error (-5)
0 == No Error
Outcomes.GOATLstEvntRslt -5 == Error (-5)
0 == No Error
Outcomes.GOATLstEvntRsltTxt
Outcomes.GOATMnthDate -15 == Three or more month error (-15)
-10 == Two month error (-10)
-5 == One month error (-5)
0 == No Error
Outcomes.GOATNeuroPsychCompCode 1.0 == 1.0 Test not done
2.0 == 2.0 Test attempted but not completed
3.0 == 3.0 Test completed
Neuropsych testing was conducted during scheduled follow-up visits to hospital according to study protocol. Cross-sectional assessments across all strata was performed at 6 mnths after injury. For patients included in the MR substudy full testing was conducted for ER patients at: 2-3 weeks, 3 mnths and 6 mnths; Adm and ICU strata: 6 mnths, 12 mnths and 24 mnths Subjects were only considered testable if the GOAT was >=65. Neuropsych testing included: GOAT, RAVLT, TMT, CANTAB subtests, 10 m walk, Timed up-and-go, as well as Participant Questionnaire B.. "Untestable" patients received the GOAT and JFK-Coma Recovery Scale-revised..
Outcomes.GOATNm -2 == Error (-2)
0 == No Error
Outcomes.GOATOutcome The total GOAT score is calculated as 100 - Total error points; Interpretation: 76-100 = Normal / 66-75 = Borderline / <66 = Impaired
Outcomes.GOATTestAttemptdNotCompOptions 2.1 == Not completed - Cognitive/neurological deficits
2.2 == Not completed - Non-neurological/physical reason
2.3 == Not completed - Lack of effort/uncooperative
2.4 == Not completed - Language
2.5 == Not completed - Illness/fatigue
2.6 == Not completed - Logistical reasons, other reasons
2.7 == Not completed - Examiner error
Documents reasons why GOAT was not completed when it was initially attempted (7 categories)
Outcomes.GOATTestAttemptdNotCompOptionsOTHER
Outcomes.GOATTestCompletedOptions 3.0 == Test completed in full - results valid
3.1 == Test completed - Non-standard, results valid
3.2 == Non-standard administration - Other
Test completed in full results valid/Test completed Nonstandard, results valid/Nonstandard administration/Other
Outcomes.GOATTestComplNonStandAdminOTHER
Outcomes.GOATTestNotDoneOptions 1.1 == Not attempted - Cognitive/neurological deficits
1.2 == Not attempted - Non-neurological/physical reasons
1.3 == Not attempted - Lack of effort/uncooperative
1.4 == Not attempted - Language
1.5 == Not attempted - Illness/fatigue
1.6 == Not attempted - Logistical reasons, other reasons
1.7 == Not attempted- Return to all normal activities
1.8 == Not attempted - Patient not available
Documents reasons why GOAT was not attempted (8 categories)
Outcomes.GOATTestNotDoneOptionsOTHER
Outcomes.GOATTime
Outcomes.GOATTotError The total error score is calculated automatically.
Outcomes.GOATTotScr The total GOAT score is calculated as 100 - Total error points; Interpretation: 76-100 = Normal / 66-75 = Borderline / <66 = Impaired
Outcomes.GOATTranspTyp -5 == Error (-5)
0 == No Error
Outcomes.GOATYrDate -30 == Three or more year error (-30)
-20 == Two year error (-20)
-10 == One year error (-10)
0 == No Error
Outcomes.GOSEAssistanceNeeded 0 == No
1 == Yes
Indicator if the participant needs another person at home essentially every day for some activities of daily living as part of Glasgow Outcome Scale Extended (GOS-E).
Outcomes.GOSEDate Date when Glasgow Outcome Scale Extended (GOS-E) (1-8) was administered.
Outcomes.GOSEEpilepsyFits 1 == No
2 == Yes
These 2 questions on epilepsy do not form part of the GOSE rating, but are included in the questionnaire as very relevant variables. Subjective reporting also in: Outcomes.PartQuestACurHltSeiz. Seizures that occurred before/at presentation or during hospital stay are recorded alsewhere: InjuryHx.EDComplEventSeizures; Vitals.HosComplEventSeizures; Hospital.HospComplSeizures; Vitals.HosComplEventSeizures; Hospital.ICUDisComplSeizure;
Outcomes.GOSEEpilepsyRisk 1 == No
2 == Yes
These 2 questions on epilepsy do not form part of the GOSE rating, but are included in the questionnaire as very relevant variables
Outcomes.GOSEFamilyDisrupt 0 == No
1 == Yes
Indicator if the participant faces any rifts in family relationships or friendships caused by psychological problems.
Outcomes.GOSEFamilyDisruptChange 0 == No
1 == Yes
Indicator if the level of disruption or strain in family and friendships depicts a change in respect to pre-injury situation
Outcomes.GOSEFamilyDisruptExtent 1 == Occasional - less than weekly (Lower GR)
2 == Frequent - once a week or more, but tolerable (Upper MD)
3 == Constant - daily and intolerable (Lower MD)
Frequency of the extent of the rifts in relationships, including family and friendships, due to psychological problems.
Outcomes.GOSEIndependentBefore 0 == No
1 == Yes
Indicator if the assistance at home was essential for the patient before the injury, as part of Glasgow Outcome Scale Extended (GOS-E).
Outcomes.GOSENeedFreqHelp 0 == No (upper SD)
1 == Yes (lower SD)
Indicator if the participant is in need of frequent help of someone to be around at home as part of Glasgow Outcome Scale Extended (GOS-E).
Outcomes.GOSEOtherCurrentProb 0 == No (upper GR)
1 == Yes (lower GR)
Indicator if the participant faces any other current problems currently due to injury
Outcomes.GOSEOtherCurrentProbWorse 0 == No
1 == Yes
Indicator if the similar problems were present before injury and have these become markedly worse.
Outcomes.GOSEOutcomeFactor 1 == Effects of head injury
2 == Effects of illness or injury to another part of the body
3 == A mixture of these
Provides an indication how much disability is not due to TBI
Outcomes.GOSEPerformed 0 == Not performed
1 == Performed/Completed
Outcomes.GOSEPostalPerformed 0 == Not performed
1 == Performed
Outcomes.GOSEPOSTAssistanceNeededFreq 1 == I do not need help or supervision in the home
2 == I need some help in the home, but not every day
3 == I need help in the home every day, but I could look after myself for at least 8 hours if necessary
4 == I could not look after myself for 8 hours during the day
5 == I need help in the home, but not because of the injury
Outcomes.GOSEPOSTComments
Outcomes.GOSEPOSTCompletionCode 1.0 == 1.0 Test completed in full
1.1 == 1.1 Non-standard adm - written
1.2 == 1.2 Non-standard adm - other
1.3 == 1.3 Test completed over the phone
2.1 == 2.1 Not completed - Cognitive/neuro
2.2 == 2.2 Not completed - Non-neuro/phys
2.3 == 2.3 Not completed - Poor effort
2.4 == 2.4 Not completed - Language
2.5 == 2.5 Not completed - Illness
2.6 == 2.6 Not completed - Logistical
3.1 == 3.1 Not attempted - Cognitive/neuro
3.2 == 3.2 Not attempted - Non-neuro/phys
3.3 == 3.3 Not attempted - Poor effort
3.4 == 3.4 Not attempted - Language
3.5 == 3.5 Not attempted - Illness
3.6 == 3.6 Not attempted - Logistical
4.0 == 4.0 Not attempted - Examiner error
5.0 == 5.0 Not attempted - Other
Outcomes.GOSEPOSTDate
Outcomes.GOSEPOSTFamilyDisruptBefore 1 == No
2 == Yes
Outcomes.GOSEPOSTFamilyDisruptChange 1 == Things are still much the same
2 == There are occasional problems (less than once a week)
3 == There are frequent problems (once a week or more)
4 == There are constant problems (problems every day)
5 == There are problems for some other reason, not because of the injury
Outcomes.GOSEPOSTIndependentBefore 1 == No
2 == Yes
Outcomes.GOSEPOSTOtherCurrentProbs 1 == I have no current problems
2 == I have some problems, but these do not interfere with my daily life
3 == I have some problems, and these have affected my daily life
4 == I have some problems for other reasons, not because of the head injury
Outcomes.GOSEPOSTOtherCurrentProbsBefore 1 == I had no problems before, I had minor problems
2 == I had similar problems before
Outcomes.GOSEPOSTPatientLocn 1 == Out of hospital
2 == In hospital or residential care
This variable describes the location of the subject (in or out hospital).
Outcomes.GOSEPOSTResponse 1 == Patient alone
2 == Relative or friend or carer alone
3 == Patient and relative, friend or carer together
This variable describes the respondent that completed the questionnaire.
Outcomes.GOSEPOSTShopAloneBefore 1 == No
2 == Yes
This variable describes if a subject is able to buy things at shops without help.
Outcomes.GOSEPOSTShopAssistance 1 == I do not need help to shop
2 == I need some help, but I can go to local shops on my own
3 == I need help to shop even locally, or I cannot shop at all
4 == I need help to shop, but not because of the injury
This variable describes if a subject needs help to buy things at shops as a result of the injury.
Outcomes.GOSEPOSTSocialActivityBefore 1 == No
2 == Yes
This variable describes if a subject did take part in regular social and leisure activities outside home (at least once a week) before the injury.
Outcomes.GOSEPOSTSocialActivityChange 1 == I take part about as often as before (the activities may be different from before)
2 == I take part a bit less, but at least half as often
3 == I take part much less, less than half as often
4 == I do not take part at all
5 == My ability to take part has changed for some other reason, not because of the injury
This variable describes if there has been a change in the subject's ability to take part in social and leisure activities outside home as a result of the injury.
Outcomes.GOSEPOSTTravelAloneBefore 1 == No
2 == Yes
This variable describes if a subject was able to travel without help before the injury.
Outcomes.GOSEPOSTTravelAssistance 1 == I do not need help to travel
2 == I need some help, but can travel locally on my own (eg. by arranging a taxi)
3 == I need help to travel even locally, or I cannot travel at all
4 == I need help to travel but not because of the injury
This variable describes if a subject needs help to travel as a result of the injury.
Outcomes.GOSEPOSTWorkBefore 1 == Working
2 == Looking for work
3 == Looking after family
4 == Studying as a student
5 == Retired
6 == None of these (eg. unfit for work)
This variable describes the employment before the injury.
Outcomes.GOSEPOSTWorkChange 1 == I still do the same work
2 == I still do the same work, but have some problems (e.g. tiredness, lack of concentration).
3 == I still work, but at a reduced level (e.g. change from full-time to part-time, or change in level of responsibility)
4 == I am unable to work, or only able to work in sheltered workshop
5 == My ability to work has changed, but not because of the injury
This variable describes the change in ability to work as a result of the injury.
Outcomes.GOSEQuestionnaireMode 1 == Telephone interview
2 == Postal questionnaire
3 == Web-based completion
4 == Personal interview
This questionnaire describes the mode in which the questionnaire is completed.
Outcomes.GOSEResponse 0 == Patient alone
1 == Relative/friend/caretaker alone
2 == Patient plus relative/friend/caretaker
This variable describes who completed the questionnaire.
Outcomes.GOSEResumeSocialActivity 0 == No
1 == Yes
This variable describes if a subject is able to resume regular social and leisure activities outside home.
Outcomes.GOSEScore 1 == 1-Dead
2 == 2-Vegetative State (VS)
3 == 3-Lower Severe Disability (Lower SD)
4 == 4-Upper Severe Disability (Upper SD)
5 == 5-Lower Moderate Disability (Lower MD)
6 == 6-Upper Moderate Disability (Upper MD)
7 == 7-Lower Good Recovery (Lower GR)
8 == 8-Upper Good Recovery (Upper GR)
This GOSE rating is assigned by the rater. In addition, a central review score will be allocated.
Outcomes.GOSEShopAlone 0 == No (upper SD)
1 == Yes
This variable describes if a subject is able to shop without assistance.
Outcomes.GOSEShopAloneBefore 0 == No
1 == Yes
This variable describes if a subject was able to shop without assistance before the injury.
Outcomes.GOSESimpleCommands 0 == No (VS)
1 == Yes
This variable describes if the subject is able to obey simple commands or say any words.
Outcomes.GOSESocialActivityRestrict 1 == Participate a bit less, at least half as often as before injury (Lower GR)
2 == Participate much less,less than half as often (Upper MD)
3 == Unable to participate,rarely, if ever, take part (Lower MD)
This variable describes the extent of restriction on the social and leisure activities.
Outcomes.GOSESocialActivityRestrictChange 0 == No
1 == Yes
This variable describes the engagement in regular social and leisure activities outside home before the injury.
Outcomes.GOSETravelAlone 0 == No (upper SD)
1 == Yes
This variable describes if the subject is able to travel locally without assistance.
Outcomes.GOSETravelAloneBefore 0 == No
1 == Yes
This variable describes if a subject was able to travel locally without assistance before the injury.
Outcomes.GOSEWork 0 == No
1 == Yes
This variable describes if a subject is currently able to work to the previous capacity.
Outcomes.GOSEWorkRestrictChange 0 == No
1 == Yes
This variable describes whether the subject was either working or seeking employment before the injury or was doing neither.
Outcomes.GOSEWorkRestriction 1 == Reduced work capacity (upper MD)
2 == Able to work only in a sheltered workshop or non-competitive job or currently unable to work (Lower MD)
Work restriction type experienced by the participant as a result of injury
Outcomes.JFKCRSRAdtyFuncScaleScore 0 == 0 - None
1 == 1 - Auditory Startle
2 == 2 - Localization to Sound
3 == 3 - Reproducible Movement to Command *
4 == 4 - Consistent Movement to Command *
Outcomes.JFKCRSRArousalScaleScore 0 == 0 - Unarousable
1 == 1 - Eye Opening with Stimulation
2 == 2 - Eye Opening w/o Stimulation
3 == 3 - Attention
Outcomes.JFKCRSRBrainStemCornRflx 1 == Absent
2 == Present Unilateral
3 == Present Bilateral
Outcomes.JFKCRSRBrainStemNotes
Outcomes.JFKCRSRBrainStemOculocRflx 1 == None
2 == Abnormal
3 == Full
4 == Normal
Outcomes.JFKCRSRBrainStemPosturalResp 1 == Abnormal Extension
2 == Abnormal Flexion
Outcomes.JFKCRSRBrainStemPosturalRespLimb
Outcomes.JFKCRSRBrainStemPupilLight 1 == Reactive
2 == Equal
3 == Constricted
4 == Dilated
5 == Pinpoint
6 == Accommodation
Outcomes.JFKCRSRBrainStemSpontEyeMvmt 1 == None
2 == Skew Deviation
3 == Conjugate Gaze Deviation
4 == Roving
5 == Dysconjugate
Outcomes.JFKCRSRCommScaleScore 0 == 0 - None
1 == 1 - Non-Functional, Intentional *
2 == 2 - Functional, Accurate &dagger
Outcomes.JFKCRSRContngntBehvrElicitgStim Supplementary item
Outcomes.JFKCRSRContngntBehvrNumElicitdOccur Supplementary item
Outcomes.JFKCRSRContngntBehvrNumSpontOccur Supplementary item
Outcomes.JFKCRSRContngntBehvrTargtBehvr Supplementary item
Outcomes.JFKCRSRDate
Outcomes.JFKCRSRMotrFuncScaleScore 0 == 0 - None/Flaccid
1 == 1 - Abnormal Posturing
2 == 2 - Flexion Withdrawal
3 == 3 - Localization to Noxious Stimulation *
4 == 4 - Object Manipulation *
5 == 5 - Automatic Motor Response *
6 == 6 - Functional Object Use†
Outcomes.JFKCRSRNeuroPsychCompCode 1.0 == 1.0 Test not done
2.0 == 2.0 Test attempted but not completed
3.0 == 3.0 Test completed
JFK Coma Recovery Scale: only applicable for patients in a minimally conscious/vegatative state
Outcomes.JFKCRSROrmtrVerbFuncScaleScore 0 == 0 - None
1 == 1 - Oral Reflexive Movement
2 == 2 - Vocalization/Oral Movement
3 == 3 - Intelligible Verbalization *
Outcomes.JFKCRSRTestAttemptdNotCompOptions 2.1 == Not completed - Cognitive/neurological deficits
2.2 == Not completed - Non-neurological/physical reason
2.3 == Not completed - Lack of effort/uncooperative
2.4 == Not completed - Language
2.5 == Not completed - Illness/fatigue
2.6 == Not completed - Logistical reasons, other reasons
2.7 == Not completed - Examiner error
Outcomes.JFKCRSRTestAttemptdNotCompOptionsOTHER
Outcomes.JFKCRSRTestCompletedOptions 3.0 == Test completed in full - results valid
3.1 == Test completed - Non-standard, results valid
3.2 == Non-standard administration - Other
Outcomes.JFKCRSRTestComplNonStandAdminOTHER
Outcomes.JFKCRSRTestNotDoneOptions 1.1 == Not attempted - Cognitive/neurological deficits
1.2 == Not attempted - Non-neurological/physical reasons
1.3 == Not attempted - Lack of effort/uncooperative
1.4 == Not attempted - Language
1.5 == Not attempted - Illness/fatigue
1.6 == Not attempted - Logistical reasons, other reasons
1.7 == Not attempted - Examiner error
1.8 == Not attempted - Patient not available
Outcomes.JFKCRSRTestNotDoneOptionsOTHER
Outcomes.JFKCRSRTotalScore
Outcomes.JFKCRSRVislFuncScaleScore 0 == 0 - None
1 == 1 - Visual Startle
2 == 2 - Fixation *
3 == 3 - Visual Pursuit *
4 == 4 - Object Localization, Reaching *
5 == 5 - Object Recognition *
Outcomes.OneHundred 100 == 100
Outcomes.PartQuestACurHltBack 0 == No
1 == Yes
This variable describes if the subject currently has back pain.
Outcomes.PartQuestACurHltHead 0 == No
1 == Yes
This variable describes if the subject currently has headaches.
Outcomes.PartQuestACurHltHear 0 == No
1 == Yes
This variable describes if the subject currently has trouble hearing.
Outcomes.PartQuestACurHltMob 0 == No
1 == Yes
This variable describes if the subject has problems with mobility/ walking.
Outcomes.PartQuestACurHltMove 0 == No
1 == Yes
This variable describes if the subject has problems with movement of hands or arms.
Outcomes.PartQuestACurHltNeck 0 == No
1 == Yes
This variable describes if the subject has neck pain or restricted neck movement.
Outcomes.PartQuestACurHltOther 0 == No
1 == Yes
This variable describes if the subject currently has any other health problems.
Outcomes.PartQuestACurHltOthertxt This variable describes any other health problems the subject currently has.
Outcomes.PartQuestACurHltSeiz 0 == No
1 == Yes
This variable describes if the subject currently has seizures (epileptic fits).
Outcomes.PartQuestACurHltSmell 0 == No
1 == Yes
This variable describes if the subject has trouble smelling or tasting.
Outcomes.PartQuestACurHltSpeech 0 == No
1 == Yes
This variable describes if the subject currently has problems with speaking or understanding others.
Outcomes.PartQuestACurHltVis 0 == No
1 == Yes
This variable describes if the subject currently has trouble with eye sight/vision (even with glasses).
Outcomes.PartQuestACurrSitChange 1 == Better
2 == About the same
3 == A little worse
4 == Worse
5 == Much worse
This variable describes how the subject compares their current situation to that before injury.
Outcomes.PartQuestACurrSitChangeReason 1 == Because of the head injury
2 == Because of other injuries received at the same time
3 == Because of illness related to the injury
4 == Some other reason, not the injury
This variable describes the reason for change in situation to that before the injury.
Outcomes.PartQuestAEmplmtStatus 1 == Return to previous job (increased level or hours from pre-injury)
2 == Return to previous job (reduced level or hours)
3 == Change of job, different work
4 == Special employment/ sheltered employment
5 == Looking for work, unemployed
6 == Unable to work
7 == Retired
8 == Student
9 == Homemaker, keeping house
88 == Unknown
This variable describes the current employment of a subject in case there was a change because of the injury.
Outcomes.PartQuestAEmplmtStatusChange 0 == No
1 == Yes
This variable describes if the subject's employment status is the same as before the injury.
Outcomes.PartQuestAMaritalStat 1 == Single (never married)
2 == Married
3 == Partnered (other than married)
4 == Separated/Divorced
5 == Widowed
This variable describes the current marital status in case there was a change because of the injury.
Outcomes.PartQuestAMaritalStatChange 0 == No
1 == Yes
This variable describes if there is a change in marital status.
Outcomes.PartQuestASatHospInj 1 == Not at all
2 == Slightly
3 == Moderately
4 == Quite
5 == Very
This variable describes how satisfied a subject is with the hospital care at the time of the injury.
Outcomes.PartQuestASatHospPostInj 1 == Not at all
2 == Slightly
3 == Moderately
4 == Quite
5 == Very
This variable describes how satisfied a subject is with the health service care afterwards (including rehabilitation).
Outcomes.PartQuestASatSupport 1 == Not at all
2 == Slightly
3 == Moderately
4 == Quite
5 == Very
This variable describes how satisfied a subject is with the availability of support from people close to them.
Outcomes.PartQuestASesPrimAdultChange 0 == No
1 == Yes
This variable describes if the living arrangements of a subject are the same as before the injury.
Outcomes.PartQuestASesPrimAdultChangePlace 1 == At home- Supported
2 == At home- Not-supported
3 == Rehabilitation centre
4 == Nursing Home
5 == Hospital
99 == Other
This variable describes the current living arrangement of a subject, in case the living arrangements are not the same as before the injury.
Outcomes.PartQuestASupHelp 1 == Information from the hospital concerning the effects of head injury
2 == Help for problems with speaking or making yourself understood (e.g. speech therapy)
3 == Help for problems with memory, attention etc (e.g. cognitive rehabilitation)
4 == Help for problems with movement (e.g. physiotherapy)
5 == Help for problems with looking after yourself in daily life (washing, cooking, toileting, mobility) (e.g. occupational therapy)
6 == Help for emotional difficulties, such as anxiety, depression, or stress
7 == Help for problems with behaviour, such as anger
8 == Help for problems with fatigue
9 == Help for managing money
10 == Help returning to work (e.g. vocational rehabilitation or employment services)
This variable describes any professional help in specific areas being given because of the injury.
Outcomes.PartQuestASupPeopleQty 0 == None
1 == 1
2 == 2-5
6 == 6-9
10 == 10 or more
This variable describes how many people a subject has near them they can readily count on for real help in times of trouble or difficulty, such as watch over children or pets, give rides to hospital or store, or help if they are sick.
Outcomes.PartQuestASupRehab 0 == No rehabilitation
1 == In-patient / residential rehabilitation
2 == Out-patient/ community rehabilitation
This variable denotes the patient perspective. Objective documentation is recorded at variable: FollowUp.FURehabNo; FollowUp.FURehabInPat; FollowUp.FURehabOutPat
Outcomes.PartQuestASupRehabNow 0 == No
1 == Yes
This variable describes if received rehabilitation is still ongoing.
Outcomes.PartQuestASupRehabTime 1 == Within 1 month of injury
2 == Between 1 and 3 months of injury
3 == Later than 3 months after injury
This variable describes when rehabilition as a result of head injury began.
Outcomes.PartQuestASupServices 1 == Hospital services
2 == Community health services
3 == Private practice
4 == Social services (e.g. social work, housing)
5 == Legal services
6 == Charity services (e.g. head injury support group)
99 == Other
Outcomes.PartQuestBAUDITCAlcDrnkTypclDayNumScore 1 == 1-2
2 == 3-4
3 == 5-6
4 == 7-9
5 == 10 or more
This variable describes the amount of drinks containing alcohol consumed on a typical day.
Outcomes.PartQuestBAUDITCDrnkContainAlcFreqScore 0 == Never
1 == Monthly or less
2 == 2-4 times a month
3 == 2-3 times a week
4 == 4 or more times a week
Detailed questions on the use of alcohol are derived from the first 3 questions of the "AUDIT" questionnaire,a screening tool developed by the World Health Organization (WHO) to assess alcohol consumption, drinking behaviors, and alcohol-related problems. The same questions are asked on in the forms on Behavioral history: InjuryHx.AUDITCDrnkContainAlcFreqScore. This aims to facilitate comparison between post- and pre-injury use.
Outcomes.PartQuestBAUDITCMoreThan6AlcDrnkFreqScore 0 == Never
1 == Less than monthly
2 == Monthly
3 == Weekly
4 == Daily or almost daily
This variable describes how often the subject has six or more drinks on one occasion.
Outcomes.PartQuestBBeforeInjAdmitHosPsy 0 == No
1 == Yes
This variable describes if the subject has been admitted to hospital for psychiatric reasons before the injury.
Outcomes.PartQuestBBeforeInjEmoDis 0 == No
1 == Yes
This variable describes if the subject ever sought treatment for emotional disorders (e.g. depression or anxiety) before the injury.
Outcomes.PartQuestBBeforeInjFamMigraine 0 == No
1 == Yes
This variable describes if the subject's parents and/or any brothers/sisters suffer from migraine.
Outcomes.PartQuestBBeforeInjLearnDis 0 == No
1 == Yes
This variable describes if the subject ever had any learning disabilities or attended special classes.
Outcomes.PartQuestBBeforeInjMentalHlt 0 == No
1 == Yes
This variable describes if the subject ever sought treatment for any other mental or health problem before the injury.
Outcomes.PartQuestBBeforeInjMob 1 == Yes
2 == No
This variable describes if the subject had mobility problems before the injury.
Outcomes.PartQuestBBeforeInjNeuro 0 == No
1 == Yes
This variable describes if the subject ever had a brain or neurological illness before the injury (e.g. epilepsy, tumour, stroke).
Outcomes.PartQuestBBeforeInjPhysLim 0 == No
1 == Yes
This variable describes if the subject had any other physical limitations before injury.
Outcomes.PartQuestBBeforeInjPrevConcus 0 == No
1 == Yes
This variable describes if the subject ever had a concussion or brain injury before the injury.
Outcomes.PartQuestBBeforeInjPrevConcusSport 0 == No
1 == Yes
This variable describes if the subject previously ever had a concussion or brain injury as a result of sports or recreational activities.
Outcomes.PartQuestBBeforeInjPrevConcusSportFreq
Outcomes.PartQuestBBeforeInjPrevConcusSportType
Outcomes.PartQuestBBeforeInjSubTrt 0 == No
1 == Yes
This variable describes if the subject has ever sought treatment for problems related to use of alcohol or drugs before the injury.
Outcomes.PartQuestBBeforeInjTreatMig 0 == No
1 == Yes
This variable describes if a subject ever sought treatment for migraine before the injury.
Outcomes.PartQuestBPerformed 0 == Not performed
1 == Performed/Completed
This variable describes if the questionnaire assessment has been performed.
Outcomes.PartQuestBQuestionnaireMode 1 == Telephone interview
2 == Postal questionnaire
3 == Web-based completion
4 == Personal interview
This variable describes the mode in which the questionnaire was completed.
Outcomes.PCL5AngryOutburstInd 0 == Not at all
1 == A little bit
2 == Moderately
3 == Quite a bit
4 == Extremely
This variable describes how much the subject was bothered by irritable behavior, angry outbursts, or acting aggressively.
Outcomes.PCL5AnswersRefTBIExp 0 == No
1 == Yes
This variable describes how much a subject is bothered when they responded to the questions in this questionnaire were the answers in reference to the stressful experience which caused the tramatic brain injury.
Outcomes.PCL5AvoidHavingFeelingInd 0 == Not at all
1 == A little bit
2 == Moderately
3 == Quite a bit
4 == Extremely
This variable describes how much the subject was bothered by avoiding memories, thoughts, or feelings related to the stressful experience.
Outcomes.PCL5AvoidSituationInd 0 == Not at all
1 == A little bit
2 == Moderately
3 == Quite a bit
4 == Extremely
This variable describes how much a subject is bothered by avoiding external reminders of the stressful experience (for example, people, places, conversations, activities, objects, or situations).
Outcomes.PCL5Blame 0 == 0-Not at all
1 == 1-A little bit
2 == 2-Moderately
3 == 3-Quite a bit
4 == 4-Extremely
This variable describes how much a subject is bothered by blaming themself or someone else strongly for the stressful experience or what happened after it.
Outcomes.PCL5Date
Outcomes.PCL5DifficultyConcentratingInd 0 == Not at all
1 == A little bit
2 == Moderately
3 == Quite a bit
4 == Extremely
This variable describes how much a subject is bothered by having difficulty concentrating.
Outcomes.PCL5DreamsInd 0 == 0-Not at all
1 == 1-A little bit
2 == 2-Moderately
3 == 3-Quite a bit
4 == 4-Extremely
This variable describes how much a subject is bothered by repeated, disturbing dreams of the stressful experience.
Outcomes.PCL5EmotionallyNumbInd 0 == Not at all
1 == A little bit
2 == Moderately
3 == Quite a bit
4 == Extremely
This variable describes how much a subject is bothered by trouble experiencing positive feelings (for example, being unable to feel happiness or have loving feelings for people close to them).
Outcomes.PCL5FallStayAsleepInd 0 == Not at all
1 == A little bit
2 == Moderately
3 == Quite a bit
4 == Extremely
This variable describes how much a subject was bothered by trouble falling or staying asleep.
Outcomes.PCL5FeelDistantInd 0 == Not at all
1 == A little bit
2 == Moderately
3 == Quite a bit
4 == Extremely
This variable describes how much the subject if bothered by feeling distant or cut off from other people.
Outcomes.PCL5HappenAgainInd 0 == Not at all
1 == A little bit
2 == Moderately
3 == Quite a bit
4 == Extremely
THis variable describes how much a subject is bothered by suddenly feeling or acting as if the stressful experience was actually happening again.
Outcomes.PCL5JumpyInd 0 == Not at all
1 == A little bit
2 == Moderately
3 == Quite a bit
4 == Extremely
This variable describes how much the subject was bothered by feeling jumpy or easily startled.
Outcomes.PCL5LossInterestInd 0 == Not at all
1 == A little bit
2 == Moderately
3 == Quite a bit
4 == Extremely
This variable described how much the subject was bothered by loss of interest in activities that they used to enjoy.
Outcomes.PCL5MemoriesInd 0 == 0-Not at all
1 == 1-A little bit
2 == 2-Moderately
3 == 3-Quite a bit
4 == 4-Extremely
This variable describes how much a subject is bothered by repeated, disturbing, and unwanted memories of the stressful experience.
Outcomes.PCL5NegBeliefsOfSelfOthersWorld 0 == Not at all
1 == A little bit
2 == Moderately
3 == Quite a bit
4 == Extremely
This variable describes how much a subject is bothered by having strong negative beliefs about themself, other people, or the world.
Outcomes.PCL5NegFeelingsFearAngerGuiltShame 0 == Not at all
1 == A little bit
2 == Moderately
3 == Quite a bit
4 == Extremely
This variable described how much the subject was bothered by having strong negative feelings such as fear, horror, anger, guilt, or shame.
Outcomes.PCL5Performed 0 == Not performed
1 == Performed/Completed
This variable describes if the questionnaire is completed.
Outcomes.PCL5PhysicalReactionsInd 0 == not at all
1 == a little bit
2 == moderately
3 == quite a bit
4 == extremely
This variable desribes how much the subject was bothered by having strong physical reactions when something reminded them of a stressful experience (for example, heart pounding, trouble breathing, sweating).
Outcomes.PCL5QuestionnaireMode 1 == Telephone interview
2 == Postal questionnaire
3 == Web-based completion
4 == Personal interview
This variable describes in which mode the questionnaire was completed.
Outcomes.PCL5RememberImportantInd 0 == Not at all
1 == A little bit
2 == Moderately
3 == Quite a bit
4 == Extremely
This variable describes how much a subject is bothered by trouble remembering important parts of the stressful experience.
Outcomes.PCL5Risk 0 == Not at all
1 == A little bit
2 == Moderately
3 == Quite a bit
4 == Extremely
This variable describes how much a subject is bothered by taking too many risks or doing things that cause them harm.
Outcomes.PCL5SuperAlertInd 0 == Not at all
1 == A little bit
2 == Moderately
3 == Quite a bit
4 == Extremely
This variable describes how much a subject is bothered by being "super-alert", watchful or on guard.
Outcomes.PCL5TotalScore Calculated centrally
Outcomes.PCL5VeryUpsetInd 0 == Not at all
1 == A little bit
2 == Moderately
3 == Quite a bit
4 == Extremely
THis variable describes how much a subject is feeling very upset when something reminded them of the stressful experience.
Outcomes.PHQ9AppteIssueScre 0 == 0 - Not at all
1 == 1 - Several days
2 == 2 - More than half the days
3 == 3 - Nearly every day
Score of how much the subject has been bothered by abnormal diet/appetite in the past two weeks, as part of the Patient Health Questionnaire (PHQ).
Outcomes.PHQ9ConcntrtnProbScre 0 == 0 - Not at all
1 == 1 - Several days
2 == 2 - More than half the days
3 == 3 - Nearly every day
Score of how much the subject has been bothered with troubling concentrating in the past two weeks, as part of the Patient Health Questionnaire (PHQ).
Outcomes.PHQ9Date
Outcomes.PHQ9DthHrtThghtScre 0 == 0 - Not at all
1 == 1 - Several days
2 == 2 - More than half the days
3 == 3 - Nearly every day
Score of how much the subject has been suffering with the thoughts of that he/she would be better off dead to hurt, as part of the Patient Health Questionnaire (PHQ).
Outcomes.PHQ9DwnDeprssnHopelssScre 0 == 0 - Not at all
1 == 1 - Several days
2 == 2 - More than half the days
3 == 3 - Nearly every day
Score of how much the subject has been feeling down and depressed in the past two weeks, as part of the Patient Health Questionnaire (PHQ).
Outcomes.PHQ9IntrstPleasrActScre 0 == 0 - Not at all
1 == 1 - Several days
2 == 2 - More than half the days
3 == 3 - Nearly every day
Score of how much the subject has been bothered by having little interest or pleasure in doing things in the past two weeks, as part of the Patient Health Questionnaire (PHQ).
Outcomes.PHQ9LowSlfEstmScre 0 == 0 - Not at all
1 == 1 - Several days
2 == 2 - More than half the days
3 == 3 - Nearly every day
Score of how much the subject has been feeling bad for himself/herself in the past two weeks, as part of the Patient Health Questionnaire (PHQ).
Outcomes.PHQ9Performed 0 == Not performed
1 == Performed/Completed
Responses for the PHQ-9 relate to how oftent the subject has been bothered in the last 2 weeks
Outcomes.PHQ9ProbsEffectOnDailyAct 0 == Not difficult at all
1 == Somewhat difficult
2 == Very difficult
3 == Extremely difficult
Only applicable if any of the 9 problem areas checked. The scale related to how difficult it is to do work, take care of things at home, or get along with other people for the subject, as part of the Patient Health Questionnaire (PHQ).
Outcomes.PHQ9QuestionnaireMode 1 == Telephone interview
2 == Postal questionnaire
3 == Web-based completion
4 == Personal interview
This reflects the mode in which the assessment was performed; this could be "personal interview", "postal questionnaire", "telephone interview" or web-based.
Outcomes.PHQ9SleepProbScre 0 == 0 - Not at all
1 == 1 - Several days
2 == 2 - More than half the days
3 == 3 - Nearly every day
Score of how much the subject has been bothered with troubling falling/staying asleep or sleeping too much in the past two weeks, as part of the Patient Health Questionnaire (PHQ).
Outcomes.PHQ9SpdMovmntSpchScre 0 == 0 - Not at all
1 == 1 - Several days
2 == 2 - More than half the days
3 == 3 - Nearly every day
Score of how much the subject has been suffering with moving or speaking too slowly in the past two weeks, as part of the Patient Health Questionnaire (PHQ).
Outcomes.PHQ9TirdLckEnrgyScre 0 == 0 - Not at all
1 == 1 - Several days
2 == 2 - More than half the days
3 == 3 - Nearly every day
Score of how much the subject has been feeling tired in the past two weeks, as part of the Patient Health Questionnaire (PHQ).
Outcomes.PHQ9TotlScre Not scored by investigator, calculated score. Total score of the questionnaire, as the part of Patient Health Questionnaire Depression (PHQ-9).
Outcomes.QoLIBRIAdlScore QoLIBRI Daily Life Autonomy Score. Calculation of QOLIBRI subscale and total scores allowed up to 1/3 of items to be missing (details at http://qolibrinet.com/scoring/).
Outcomes.QoLIBRICogScore QoLIBRI Cognition Score. Calculation of QOLIBRI subscale and total scores allowed up to 1/3 of items to be missing (details at http://qolibrinet.com/scoring/).
Outcomes.QoLIBRIDate
Outcomes.QoLIBRIEmoScore QoLIBRI Emotional Score. Calculation of QOLIBRI subscale and total scores allowed up to 1/3 of items to be missing (details at http://qolibrinet.com/scoring/).
Outcomes.QoLIBRIEmotAchievmnts 1 == 1- Not at all
2 == 2- Slightly
3 == 3- Moderately
4 == 4- Quite
5 == 5- Very
This variable describes how satisfied the subject is with what they have achieved since the brain injury.
Outcomes.QoLIBRIEmotAppearnce 1 == 1- Not at all
2 == 2- Slightly
3 == 3- Moderately
4 == 4- Quite
5 == 5- Very
Outcomes.QoLIBRIEmotEnergy 1 == 1- Not at all
2 == 2- Slightly
3 == 3- Moderately
4 == 4- Quite
5 == 5- Very
This variable describes how satisfied the subject is with their level of energy.
Outcomes.QoLIBRIEmotFuture 1 == 1- Not at all
2 == 2- Slightly
3 == 3- Moderately
4 == 4- Quite
5 == 5- Very
Outcomes.QoLIBRIEmotMotivtn 1 == 1- Not at all
2 == 2- Slightly
3 == 3- Moderately
4 == 4- Quite
5 == 5- Very
Outcomes.QoLIBRIEmotSelfEstm 1 == 1- Not at all
2 == 2- Slightly
3 == 3- Moderately
4 == 4- Quite
5 == 5- Very
Outcomes.QoLIBRIEmotSelfPerceptn 1 == 1- Not at all
2 == 2- Slightly
3 == 3- Moderately
4 == 4- Quite
5 == 5- Very
Outcomes.QoLIBRIFeelAngry 1 == 1- Not at all
2 == 2- Slightly
3 == 3- Moderately
4 == 4- Quite
5 == 5- Very
Outcomes.QoLIBRIFeelAnxious 1 == 1- Not at all
2 == 2- Slightly
3 == 3- Moderately
4 == 4- Quite
5 == 5- Very
Outcomes.QoLIBRIFeelBored 1 == 1- Not at all
2 == 2- Slightly
3 == 3- Moderately
4 == 4- Quite
5 == 5- Very
Outcomes.QoLIBRIFeelLonely 1 == 1- Not at all
2 == 2- Slightly
3 == 3- Moderately
4 == 4- Quite
5 == 5- Very
Outcomes.QoLIBRIFeelSad 1 == 1- Not at all
2 == 2- Slightly
3 == 3- Moderately
4 == 4- Quite
5 == 5- Very
Outcomes.QoLIBRIIndpDomesticAct 1 == Not at all
2 == Slightly
3 == Moderately
4 == Quite
5 == Very
Outcomes.QoLIBRIIndpExtent 1 == Not at all
2 == Slightly
3 == Moderately
4 == Quite
5 == Very
Outcomes.QoLIBRIIndpOutAbout 1 == Not at all
2 == Slightly
3 == Moderately
4 == Quite
5 == Very
Outcomes.QoLIBRIIndpOwnLife 1 == Not at all
2 == Slightly
3 == Moderately
4 == Quite
5 == Very
Outcomes.QoLIBRIIndpPersonalFin 1 == Not at all
2 == Slightly
3 == Moderately
4 == Quite
5 == Very
Outcomes.QoLIBRIIndpSocAct 1 == Not at all
2 == Slightly
3 == Moderately
4 == Quite
5 == Very
Outcomes.QoLIBRIIndpWrkEd 1 == Not at all
2 == Slightly
3 == Moderately
4 == Quite
5 == Very
Outcomes.QoLIBRIOSBrainWorking 1 == Not at all
2 == Slightly
3 == Moderately
4 == Quite
5 == Very
Outcomes.QoLIBRIOSCompleteBy 1 == Patient alone
2 == Relative or friend or carer alone
3 == Patient and relative, friend or carer together
Outcomes.QoLIBRIOSCurrSituationFutureProspects 1 == Not at all
2 == Slightly
3 == Moderately
4 == Quite
5 == Very
Outcomes.QoLIBRIOSDate
Outcomes.QoLIBRIOSDayToDay 1 == Not at all
2 == Slightly
3 == Moderately
4 == Quite
5 == Very
Outcomes.QoLIBRIOSFeelingsEmotions 1 == Not at all
2 == Slightly
3 == Moderately
4 == Quite
5 == Very
Outcomes.QoLIBRIOSPerformed 0 == Not performed
1 == Performed/Completed
This variable describes if the questionnaire assessment is performed.
Outcomes.QoLIBRIOSPersonalSocialLife 1 == Not at all
2 == Slightly
3 == Moderately
4 == Quite
5 == Very
This variable described how satisfied a subject is with their personal and social life.
Outcomes.QoLIBRIOSPhysCondition 1 == Not at all
2 == Slightly
3 == Moderately
4 == Quite
5 == Very
Outcomes.QoLIBRIOSQuestionnaireMode 1 == Telephone interview
2 == Postal questionnaire
3 == Web-based completion
4 == Personal interview
This variable informs how the assessment was performed. Could be "Personal interview", "Postal questionnaire", "Telephone interview" or "Web-based completion".
Outcomes.QoLIBRIOStartTime
Outcomes.QoLIBRIOStopTime
Outcomes.QoLIBRIOSTotalScore Total score for Qolibri-OS
Outcomes.QoLIBRIOTimeSpent
Outcomes.QoLIBRIPerformed 0 == Not performed
1 == Performed/Completed
This variable informs if the assessment was performed or not
Outcomes.QoLIBRIPhysProbBrainInj 1 == 1- Not at all
2 == 2- Slightly
3 == 3- Moderately
4 == 4- Quite
5 == 5- Very
Outcomes.QoLIBRIPhysProbInjs 1 == 1- Not at all
2 == 2- Slightly
3 == 3- Moderately
4 == 4- Quite
5 == 5- Very
Outcomes.QoLIBRIPhysProbPain 1 == 1- Not at all
2 == 2- Slightly
3 == 3- Moderately
4 == 4- Quite
5 == 5- Very
Outcomes.QoLIBRIPhysProbSeeHear 1 == 1- Not at all
2 == 2- Slightly
3 == 3- Moderately
4 == 4- Quite
5 == 5- Very
Outcomes.QoLIBRIPhysProbSlow 1 == 1- Not at all
2 == 2- Slightly
3 == 3- Moderately
4 == 4- Quite
5 == 5- Very
Outcomes.QoLIBRIPhysScore QoLIBRI Physical Score. Calculation of QOLIBRI subscale and total scores allowed up to 1/3 of items to be missing (details at http://qolibrinet.com/scoring/).
Outcomes.QoLIBRIQuestionnaireMode 1 == Telephone interview
2 == Postal questionnaire
3 == Web-based completion
4 == Personal interview
The mode in which the assessment was performed
Outcomes.QoLIBRISelfScore QoLIBRI Self Score. Calculation of QOLIBRI subscale and total scores allowed up to 1/3 of items to be missing (details at http://qolibrinet.com/scoring/).
Outcomes.QoLIBRISocRelAffectn 1 == Not at all
2 == Slightly
3 == Moderately
4 == Quite
5 == Very
Outcomes.QoLIBRISocRelAttitudes 1 == Not at all
2 == Slightly
3 == Moderately
4 == Quite
5 == Very
Outcomes.QoLIBRISocRelFamily 1 == Not at all
2 == Slightly
3 == Moderately
4 == Quite
5 == Very
Outcomes.QoLIBRISocRelFriends 1 == 1- Not at all
2 == 2- Slightly
3 == 3- Moderately
4 == 4- Quite
5 == 5- Very
Outcomes.QoLIBRISocRelPartner 1 == 1- Not at all
2 == 2- Slightly
3 == 3- Moderately
4 == 4- Quite
5 == 5- Very
Outcomes.QoLIBRISocRelSexLife 1 == 1- Not at all
2 == 2- Slightly
3 == 3- Moderately
4 == 4- Quite
5 == 5- Very
Outcomes.QoLIBRISocScore QoLIBRI Social Score. Calculation of QOLIBRI subscale and total scores allowed up to 1/3 of items to be missing (details at http://qolibrinet.com/scoring/).
Outcomes.QoLIBRIThnkConcentrate 1 == 1- Not at all
2 == 2- Slightly
3 == 3- Moderately
4 == 4- Quite
5 == 5- Very
Questions relate to how the subject feels now (including last week)
Outcomes.QoLIBRIThnkDecisions 1 == 1- Not at all
2 == 2- Slightly
3 == 3- Moderately
4 == 4- Quite
5 == 5- Very
Outcomes.QoLIBRIThnkExpress 1 == 1- Not at all
2 == 2- Slightly
3 == 3- Moderately
4 == 4- Quite
5 == 5- Very
Outcomes.QoLIBRIThnkMemory 1 == 1- Not at all
2 == 2- Slightly
3 == 3- Moderately
4 == 4- Quite
5 == 5- Very
Outcomes.QoLIBRIThnkNavigate 1 == 1- Not at all
2 == 2- Slightly
3 == 3- Moderately
4 == 4- Quite
5 == 5- Very
Outcomes.QoLIBRIThnkSolns 1 == 1- Not at all
2 == 2- Slightly
3 == 3- Moderately
4 == 4- Quite
5 == 5- Very
Outcomes.QoLIBRIThnkSpeed 1 == 1- Not at all
2 == 2- Slightly
3 == 3- Moderately
4 == 4- Quite
5 == 5- Very
Outcomes.QoLIBRITotalScore QoLIBRI Total Score. Calculation of QOLIBRI subscale and total scores allowed up to 1/3 of items to be missing (details at http://qolibrinet.com/scoring/).
Outcomes.RAVLT20MinDelayPrincipalList7
Outcomes.RAVLTCompletionCode 1.0 == 1.0 Test completed in full
1.1 == 1.1 Non-standard adm - written
1.2 == 1.2 Non-standard adm - other
1.3 == 1.3 Test completed over the phone
2.1 == 2.1 Not completed - Cognitive/neuro
2.2 == 2.2 Not completed - Non-neuro/phys
2.3 == 2.3 Not completed - Poor effort
2.4 == 2.4 Not completed - Language
2.5 == 2.5 Not completed - Illness
2.6 == 2.6 Not completed - Logstical
3.1 == 3.1 Not attempted - Cognitive/neuro
3.2 == 3.2 Not attempted - Non-neuro/phys
3.3 == 3.3 Not attempted - Poor effort
3.4 == 3.4 Not attempted - Language
3.5 == 3.5 Not attempted - Illness
3.6 == 3.6 Not attempted - Logistical
4.0 == 4.0 Not attempted - Examiner error
5.0 == 5.0 Other
Outcomes.RAVLTDate
Outcomes.RAVLTInterferenceList1
Outcomes.RAVLTNeuroPsychCompCode 1.0 == 1.0 Test not done
2.0 == 2.0 Test attempted but not completed
3.0 == 3.0 Test completed
Outcomes.RAVLTPrincipalList1
Outcomes.RAVLTPrincipalList2
Outcomes.RAVLTPrincipalList3
Outcomes.RAVLTPrincipalList4
Outcomes.RAVLTPrincipalList5
Outcomes.RAVLTPrincipalListRecall6
Outcomes.RAVLTTestAttemptdNotCompOptions 2.1 == Not completed - Cognitive/neurological deficits
2.2 == Not completed - Non-neurological/physical reason
2.3 == Not completed - Lack of effort/uncooperative
2.4 == Not completed - Language
2.5 == Not completed - Illness/fatigue
2.6 == Not completed - Logistical reasons, other reasons
2.7 == Not completed - Examiner error
If the test was attempted but not completed, this variable specifies the reason.
Outcomes.RAVLTTestAttemptdNotCompOptionsOTHER If the reason why the test was attempted but not completed, was another reason than pre-defined, the other reason must be specified here.
Outcomes.RAVLTTestCompletedOptions 3.0 == Test completed in full - results valid
3.1 == Test completed - Non-standard, results valid
3.2 == Non-standard administration - Other
If the Test was completed, this variable was to specify how it was completed.
Outcomes.RAVLTTestComplNonStandAdminOTHER
Outcomes.RAVLTTestNotDoneOptions 1.1 == Not attempted - Cognitive/neurological deficits
1.2 == Not attempted - Non-neurological/physical reasons
1.3 == Not attempted - Lack of effort/uncooperative
1.4 == Not attempted - Language
1.5 == Not attempted - Illness/fatigue
1.6 == Not attempted - Logistical reasons, other reasons
1.7 == Not attempted - Examiner error
1.8 == Not attempted - Patient not available
This variable described why the test is not done.
Outcomes.RAVLTTestNotDoneOptionsOTHER
Outcomes.RAVLTTotalScorePrincipal Rey Auditory Verbal Learning Test Total Score. Calculated centrally.
Outcomes.RAVLTWordListNum 1 == 1
2 == 2
3 == 3
Indicates which RAVLT Word List Form was used for the asessment
Outcomes.RPQ13Score Not scored by investigator, calculated score
Outcomes.RPQ3Score Not scored by investigator, calculated score
Outcomes.RPQBlurredVision 0 == Not experienced at all
1 == No more of a problem
2 == A mild problem
3 == A moderate problem
4 == A severe problem
Outcomes.RPQDate Baseline RPQ documents complaints and symptoms commonly reported after TBI. Baseline RPQ can only be assessed in conscious subjects who are out of PTA. Provides further details on AOC.
Outcomes.RPQDepressed 0 == Not experienced at all
1 == No more of a problem
2 == A mild problem
3 == A moderate problem
4 == A severe problem
Outcomes.RPQDizziness 0 == Not experienced at all
1 == No more of a problem
2 == A mild problem
3 == A moderate problem
4 == A severe problem
Outcomes.RPQDoubleVision 0 == Not experienced at all
1 == No more of a problem
2 == A mild problem
3 == A moderate problem
4 == A severe problem
Outcomes.RPQFatigue 0 == Not experienced at all
1 == No more of a problem
2 == A mild problem
3 == A moderate problem
4 == A severe problem
Outcomes.RPQForgetful 0 == Not experienced at all
1 == No more of a problem
2 == A mild problem
3 == A moderate problem
4 == A severe problem
Outcomes.RPQFrustrated 0 == Not experienced at all
1 == No more of a problem
2 == A mild problem
3 == A moderate problem
4 == A severe problem
Outcomes.RPQHeadaches 0 == 0-Not experienced at all
1 == 1- No more of a problem
2 == 2- A mild problem
3 == 3- A moderate problem
4 == 4- A severe problem
Scoring of symptoms in RPQ: 0=none; 1=no more of a problem; 2=a mild problem; 3= a moderate problem; 4= a severe problem.
Outcomes.RPQIrritable 0 == Not experienced at all
1 == No more of a problem
2 == A mild problem
3 == A moderate problem
4 == A severe problem
Outcomes.RPQLightSensitivity 0 == 0-Not experienced at all
1 == 1- No more of a problem
2 == 2- A mild problem
3 == 3- A moderate problem
4 == 4- A severe problem
Outcomes.RPQLongerToThink 0 == Not experienced at all
1 == No more of a problem
2 == A mild problem
3 == A moderate problem
4 == A severe problem
Outcomes.RPQNausea 0 == Not experienced at all
1 == No more of a problem
2 == A mild problem
3 == A moderate problem
4 == A severe problem
Outcomes.RPQNoiseSensitivity 0 == Not experienced at all
1 == No more of a problem
2 == A mild problem
3 == A moderate problem
4 == A severe problem
Outcomes.RPQOther1 0 == 0-Not experienced at all
1 == 1-No more of a problem
2 == 2-A mild problem
3 == 3-A moderate problem
4 == 4-A severe problem
Outcomes.RPQOther1Text
Outcomes.RPQOther2 0 == 0-Not experienced at all
1 == 1-No more of a problem
2 == 2-A mild problem
3 == 3-A moderate problem
4 == 4-A severe problem
Outcomes.RPQOther2Text
Outcomes.RPQPerformed 0 == Not performed
1 == Performed/Completed
Reflects is the assessment was performed or not
Outcomes.RPQPoorConcentration 0 == 0-Not experienced at all
1 == 1- No more of a problem
2 == 2- A mild problem
3 == 3- A moderate problem
4 == 4- A severe problem
Outcomes.RPQQuestionnaireMode 1 == Telephone interview
2 == Postal questionnaire
3 == Web-based completion
4 == Personal interview
The mode in which the assessment was performed; could be "Personal interview", "Postal questionnaire", "Telephone interview", "Web-based completion"
Outcomes.RPQRestless 0 == 0-Not experienced at all
1 == 1- No more of a problem
2 == 2- A mild problem
3 == 3- A moderate problem
4 == 4- A severe problem
Outcomes.RPQSleepDisturbance 0 == 0-Not experienced at all
1 == 1- No more of a problem
2 == 2- A mild problem
3 == 3- A moderate problem
4 == 4- A severe problem
Outcomes.RPQTime
Outcomes.RPQTotalScore RPQ(Rivermead post-concussion symptoms questionnaire) Total Score. Calculated centrally.
Outcomes.SF12Date
Outcomes.SF12EmotProbLessAccomp 1 == 1 - All of the time
2 == 2 - Most of the time
3 == 3 - Some of the time
4 == 4 - A little of the time
5 == 5 - None of the time
Question relates to the past 4 weeks
Outcomes.SF12EmotProbWkLessCare 1 == 1 - All of the time
2 == 2 - Most of the time
3 == 3 - Some of the time
4 == 4 - A little of the time
5 == 5 - None of the time
Question relates to the past 4 weeks; Please note: This question appears to have been mis-phrased" in the English version of the e-CRF but was correct on the pdf questionnaires used by the outcome assessors.
Outcomes.SF12GenHlth 1 == 1 - Excellent
2 == 2 - Very Good
3 == 3 - Good
4 == 4 - Fair
5 == 5 - Poor
Outcomes.SF12HlthLmtClmbSvrlFlStair 1 == 1 - Yes, Limited A Lot
2 == 2 - Yes, Limited A Little
3 == 3 - No, Not Limited At All
Outcomes.SF12HlthLmtModAct 1 == 1 - Yes, Limited A Lot
2 == 2 - Yes, Limited A Little
3 == 3 - No, Not Limited At All
Outcomes.SF12PainInterfWrk 1 == 1 - Not At All
2 == 2 - A Little Bit
3 == 3 - Moderately
4 == 4 - Quite A Bit
5 == 5 - Extremely
Question relates to the past 4 weeks
Outcomes.SF12Performed 0 == Not performed
1 == Performed/Completed
Outcomes.SF12PhyEmotInterfSoc 1 == 1 - All of the time
2 == 2 - Most of the time
3 == 3 - Some of the time
4 == 4 - A little of the time
5 == 5 - None of the time
Question relates to the past 4 weeks
Outcomes.SF12PhyHlthLessAccomp 1 == 1 - All of the time
2 == 2 - Most of the time
3 == 3 - Some of the time
4 == 4 - A little of the time
5 == 5 - None of the time
Question relates to the past 4 weeks
Outcomes.SF12PhyHlthLmtWrkAct 1 == 1 - All of the time
2 == 2 - Most of the time
3 == 3 - Some of the time
4 == 4 - A little of the time
5 == 5 - None of the time
Question relates to the past 4 weeks
Outcomes.SF12QuestionnaireMode 1 == Telephone interview
2 == Postal questionnaire
3 == Web-based completion
4 == Personal interview
This variable reflects the mode of the assessment: it could be "Personal interview", "Postal questionnaire", "Telephone interview" or "Web-based completion"
Outcomes.SF12ScoreBP SF-12v2. Bodily Pain - Scored on a 0-100 scale
Outcomes.SF12ScoreBPNBS SF-12v2. Bodily Pain Norm-Based Score - T-score using 1998 norms and maximum data recovery (Acute at 2 weeks and standard at other timepoints)
Outcomes.SF12ScoreGH SF-12v2. General Health (GH) - Scored on a 0-100 scale
Outcomes.SF12ScoreGHNBS SF-12v2. General Health (GH) Norm-Based Score - T-score using 1998 norms and maximum data recovery (Acute at 2 weeks and standard at other timepoints)
Outcomes.SF12ScoreHMNBS SF-12v2. Mental Health (MH) Norm-Based Score - T-score using 1998 norms and maximum data recovery (Acute at 2 weeks and standard at other timepoints)
Outcomes.SF12ScoreMCS SF-12v2. Mental Component Summary - T-score using 1998 norms and maximum data recovery (Acute at 2 weeks and standard at other timepoints)
Outcomes.SF12ScoreMH SF-12v2. Mental Health (MH) - Scored on a 0-100 scale
Outcomes.SF12ScorePCS SF-12v2. Physical Component Summary - T-score using 1998 norms and maximum data recovery (Acute at 2 weeks and standard at other timepoints)
Outcomes.SF12ScorePF SF-12v2. Physical Functioning - Scored on a 0-100 scale
Outcomes.SF12ScorePFNBS SF-12v2. Physical Functioning Norm-Based Score - T-score using 1998 norms and maximum data recovery (Acute at 2 weeks and standard at other timepoints)
Outcomes.SF12ScoreRE SF-12v2. Role-Emotional (RE) - Scored on a 0-100 scale
Outcomes.SF12ScoreRENBS SF-12v2. Role-Emotional (RE) Norm-Based Score - T-score using 1998 norms and maximum data recovery (Acute at 2 weeks and standard at other timepoints)
Outcomes.SF12ScoreRP SF-12v2. Role-Physical (RP) - Scored on a 0-100 scale
Outcomes.SF12ScoreRPNBS SF-12v2. Role-Physical (RP) Norm-Based Score - T-score using 1998 norms and maximum data recovery (Acute at 2 weeks and standard at other timepoints)
Outcomes.SF12ScoreSF SF-12v2. Social Functioning - Scored on a 0-100 scale
Outcomes.SF12ScoreSFNBS SF-12v2. Social Functioning Norm-Based Score - T-score using 1998 norms and maximum data recovery (Acute at 2 weeks and standard at other timepoints)
Outcomes.SF12ScoreVT SF-12v2. Vitality - Scored on a 0-100 scale
Outcomes.SF12ScoreVTNBS SF-12v2. Vitality Norm-Based Score - T-score using 1998 norms and maximum data recovery (Acute at 2 weeks and standard at other timepoints)
Outcomes.SF12TimesFeelCalmPcful 1 == 1 - All of the time
2 == 2 - Most of the time
3 == 3 - Some of the time
4 == 4 - A little of the time
5 == 5 - None of the time
Question relates to the past 4 weeks
Outcomes.SF12TimesFeelDown 1 == 1 - All of the time
2 == 2 - Most of the time
3 == 3 - Some of the time
4 == 4 - A little of the time
5 == 5 - None of the time
Question relates to the past 4 weeks
Outcomes.SF12TimesFeelEnergetic 1 == 1 - All of the time
2 == 2 - Most of the time
3 == 3 - Some of the time
4 == 4 - A little of the time
5 == 5 - None of the time
Question relates to the past 4 weeks
Outcomes.SF36AsHlthy 1 == 1 - Definitely true
2 == 2 - Mostly true
3 == 3 - Don't know
4 == 4 - Mostly false
5 == 5 - Definitely false
Outcomes.SF36Date
Outcomes.SF36EmotProbLessAccomp 1 == 1 - All of the time
2 == 2 - Most of the time
3 == 3 - Some of the time
4 == 4 - A little of the time
5 == 5 - None of the time
Question relates to the past 4 weeks
Outcomes.SF36EmtProbCutTimeWrk 1 == 1 - All of the time
2 == 2 - Most of the time
3 == 3 - Some of the time
4 == 4 - A little of the time
5 == 5 - None of the time
Question relates to the past 4 weeks
Outcomes.SF36EmtProbLessCare 1 == 1 - All of the time
2 == 2 - Most of the time
3 == 3 - Some of the time
4 == 4 - A little of the time
5 == 5 - None of the time
Question relates to the past 4 weeks
Outcomes.SF36ExpctWrseHlth 1 == 1 - Definitely true
2 == 2 - Mostly true
3 == 3 - Don't know
4 == 4 - Mostly false
5 == 5 - Definitely false
Outcomes.SF36GenHlth 1 == 1 - Excellent
2 == 2 - Very good
3 == 3 - Good
4 == 4 - Fair
5 == 5 - Poor
Outcomes.SF36HlthExcllnt 1 == 1 - Definitely true
2 == 2 - Mostly true
3 == 3 - Don't know
4 == 4 - Mostly false
5 == 5 - Definitely false
Outcomes.SF36HlthLmtBathDress 1 == 1 - Yes, limited a lot.
2 == 2 - Yes, limited a little.
3 == 3 - No, not limited at all.
Outcomes.SF36HlthLmtBendKneel 1 == 1 - Yes, limited a lot.
2 == 2 - Yes, limited a little.
3 == 3 - No, not limited at all.
Outcomes.SF36HlthLmtClmbOneFlStair 1 == 1 - Yes, limited a lot.
2 == 2 - Yes, limited a little.
3 == 3 - No, not limited at all.
Outcomes.SF36HlthLmtClmbSvrlFlStair 1 == 1 - Yes, limited a lot.
2 == 2 - Yes, limited a little.
3 == 3 - No, not limited at all.
Outcomes.SF36HlthLmtLiftCarry 1 == 1 - Yes, limited a lot.
2 == 2 - Yes, limited a little.
3 == 3 - No, not limited at all.
Outcomes.SF36HlthLmtModAct 1 == 1 - Yes, limited a lot.
2 == 2 - Yes, limited a little.
3 == 3 - No, not limited at all.
Outcomes.SF36HlthLmtVigAct 1 == 1 - Yes, limited a lot.
2 == 2 - Yes, limited a little.
3 == 3 - No, not limited at all.
Outcomes.SF36HlthLmtWalkHndrdYards 1 == 1 - Yes, limited a lot.
2 == 2 - Yes, limited a little.
3 == 3 - No, not limited at all.
Outcomes.SF36HlthLmtWalkMile 1 == 1 - Yes, limited a lot.
2 == 2 - Yes, limited a little.
3 == 3 - No, not limited at all.
Outcomes.SF36HlthLmtWalkSvrlHndrdYards 1 == 1 - Yes, limited a lot.
2 == 2 - Yes, limited a little.
3 == 3 - No, not limited at all.
Outcomes.SF36HlthOneYrAgo 1 == 1 - Much better now than a year ago
2 == 2 - Somewhat better now than a year ago
3 == 3 - About the same as one year ago
4 == 4 - Somewhat worse now than one year ago
5 == 5 - Much worse now than one year ago
Outcomes.SF36IllMoreEasily 1 == 1 - Definitely true
2 == 2 - Mostly true
3 == 3 - Don't know
4 == 4 - Mostly false
5 == 5 - Definitely false
Outcomes.SF36LvlBodPain 1 == 1 - None
2 == 2 - Very mild
3 == 3 - Mild
4 == 4 - Moderate
5 == 5 - Severe
6 == 6 - Very severe
Question relates to the past 4 weeks
Outcomes.SF36PainInterfWrk 1 == 1 - Not at all
2 == 2 - A little bit
3 == 3 - Moderately
4 == 4 - Quite a bit
5 == 5 - Extremely
Question relates to the past 4 weeks
Outcomes.SF36Performed 0 == Not performed
1 == Performed/Completed
Indicates if the SF-36 assessment was performed or not
Outcomes.SF36PhysEmotInterfNormSoc 1 == 1 - Not at all
2 == 2 - Slightly
3 == 3 - Moderately
4 == 4 - Quite a bit
5 == 5 - Extremely
Question relates to the past 4 weeks
Outcomes.SF36PhysEmotInterfSoc 1 == 1 - All of the time
2 == 2 - Most of the time
3 == 3 - Some of the time
4 == 4 - A little of the time
5 == 5 - None of the time
Question relates to the past 4 weeks
Outcomes.SF36PhysHlthCutTimeWrk 1 == 1 - All of the time
2 == 2 - Most of the time
3 == 3 - Some of the time
4 == 4 - A little of the time
5 == 5 - None of the time
Question relates to the past 4 weeks
Outcomes.SF36PhysHlthDiffWrkAct 1 == 1 - All of the time
2 == 2 - Most of the time
3 == 3 - Some of the time
4 == 4 - A little of the time
5 == 5 - None of the time
Question relates to the past 4 weeks
Outcomes.SF36PhysHlthLessAccomp 1 == 1 - All of the time
2 == 2 - Most of the time
3 == 3 - Some of the time
4 == 4 - A little of the time
5 == 5 - None of the time
Question relates to the past 4 weeks
Outcomes.SF36PhysHlthLmtWrkAct 1 == 1 - All of the time
2 == 2 - Most of the time
3 == 3 - Some of the time
4 == 4 - A little of the time
5 == 5 - None of the time
Question relates to the past 4 weeks
Outcomes.SF36QuestionnaireMode 1 == Telephone interview
2 == Postal questionnaire
3 == Web-based completion
4 == Personal interview
The mode of assessment ; this could be "Personal interview", "Postal questionnaire", "Telephone interview" or "Web-based completion"
Outcomes.SF36ScoreBP SF-36v2. Bodily Pain - Scored on a 0-100 scale
Outcomes.SF36ScoreBPNBS SF-36v2. Bodily Pain Norm-Based Score - T-score using 1998 norms and maximum data recovery (Acute at 2 weeks and standard at other timepoints)
Outcomes.SF36ScoreGH SF-36v2. General Health (GH) - Scored on a 0-100 scale
Outcomes.SF36ScoreGHNBS SF-36v2. General Health (GH) Norm-Based Score - T-score using 1998 norms and maximum data recovery (Acute at 2 weeks and standard at other timepoints)
Outcomes.SF36ScoreHMNBS SF-36v2. Mental Health (MH) Norm-Based Score - T-score using 1998 norms and maximum data recovery (Acute at 2 weeks and standard at other timepoints)
Outcomes.SF36ScoreMCS SF-36v2. Mental Component Summary - T-score using 1998 norms and maximum data recovery (Acute at 2 weeks and standard at other timepoints)
Outcomes.SF36ScoreMH SF-36v2. Mental Health (MH) - Scored on a 0-100 scale
Outcomes.SF36ScorePCS SF-36v2. Physical Component Summary - T-score using 1998 norms and maximum data recovery (Acute at 2 weeks and standard at other timepoints)
Outcomes.SF36ScorePF SF-36v2. Physical Functioning - Scored on a 0-100 scale
Outcomes.SF36ScorePFNBS SF-36v2. Physical Functioning Norm-Based Score - T-score using 1998 norms and maximum data recovery (Acute at 2 weeks and standard at other timepoints)
Outcomes.SF36ScoreRE SF-36v2. Role-Emotional (RE) - Scored on a 0-100 scale
Outcomes.SF36ScoreRENBS SF-36v2. Role-Emotional (RE) Norm-Based Score - T-score using 1998 norms and maximum data recovery (Acute at 2 weeks and standard at other timepoints)
Outcomes.SF36ScoreRP SF-36v2. Role-Physical (RP) - Scored on a 0-100 scale
Outcomes.SF36ScoreRPNBS SF-36v2. Role-Physical (RP) Norm-Based Score - T-score using 1998 norms and maximum data recovery (Acute at 2 weeks and standard at other timepoints)
Outcomes.SF36ScoreSF SF-36v2. Social Functioning - Scored on a 0-100 scale
Outcomes.SF36ScoreSFNBS SF-36v2. Social Functioning Norm-Based Score - T-score using 1998 norms and maximum data recovery (Acute at 2 weeks and standard at other timepoints)
Outcomes.SF36ScoreVT SF-36v2. Vitality - Scored on a 0-100 scale
Outcomes.SF36ScoreVTNBS SF-36v2. Vitality Norm-Based Score - T-score using 1998 norms and maximum data recovery (Acute at 2 weeks and standard at other timepoints)
Outcomes.SF36TimesFeelCalmPcful 1 == 1 - All of the time
2 == 2 - Most of the time
3 == 3 - Some of the time
4 == 4 - A little of the time
5 == 5 - None of the time
Question relates to the past 4 weeks
Outcomes.SF36TimesFeelDown 1 == 1 - All of the time
2 == 2 - Most of the time
3 == 3 - Some of the time
4 == 4 - A little of the time
5 == 5 - None of the time
Question relates to the past 4 weeks
Outcomes.SF36TimesFeelDumps 1 == 1 - All of the time
2 == 2 - Most of the time
3 == 3 - Some of the time
4 == 4 - A little of the time
5 == 5 - None of the time
Question relates to the past 4 weeks
Outcomes.SF36TimesFeelEnergetic 1 == 1 - All of the time
2 == 2 - Most of the time
3 == 3 - Some of the time
4 == 4 - A little of the time
5 == 5 - None of the time
Question relates to the past 4 weeks
Outcomes.SF36TimesFeelFullLife 1 == 1 - All of the time
2 == 2 - Most of the time
3 == 3 - Some of the time
4 == 4 - A little of the time
5 == 5 - None of the time
Question relates to the past 4 weeks
Outcomes.SF36TimesFeelHappy 1 == 1 - All of the time
2 == 2 - Most of the time
3 == 3 - Some of the time
4 == 4 - A little of the time
5 == 5 - None of the time
Question relates to the past 4 weeks
Outcomes.SF36TimesFeelNerv 1 == 1 - All of the time
2 == 2 - Most of the time
3 == 3 - Some of the time
4 == 4 - A little of the time
5 == 5 - None of the time
Question relates to the past 4 weeks
Outcomes.SF36TimesFeelTired 1 == 1 - All of the time
2 == 2 - Most of the time
3 == 3 - Some of the time
4 == 4 - A little of the time
5 == 5 - None of the time
Question relates to the past 4 weeks
Outcomes.SF36TimesFeelWornOut 1 == 1 - All of the time
2 == 2 - Most of the time
3 == 3 - Some of the time
4 == 4 - A little of the time
5 == 5 - None of the time
Question relates to the past 4 weeks
Outcomes.Timepoint Base == Baseline
2wk == 2 weeks
3mo == 3 months
6mo == 6 months
12mo == 12 months
24mo == 24 months
Outcome timepoints are 2-3 weeks, 3 months, 6 months, 12 months and 24 months. Depending on the stratum and sub-studies of a patient, follow up was performed at some of these time points or at all timepoints. For an overview, please check the SOP Manual.
Outcomes.TMTCompletionCode 1.0 == 1.0 Test completed in full
1.1 == 1.1 Non-standard adm - written
1.2 == 1.2 Non-standard adm - other
1.3 == 1.3 Test completed over the phone
2.1 == 2.1 Not completed - Cognitive/neuro
2.2 == 2.2 Not completed - Non-neuro/phys
2.3 == 2.3 Not completed - Poor effort
2.4 == 2.4 Not completed - Language
2.5 == 2.5 Not completed - Illness
2.6 == 2.6 Not completed - Logstical
3.1 == 3.1 Not attempted - Cognitive/neuro
3.2 == 3.2 Not attempted - Non-neuro/phys
3.3 == 3.3 Not attempted - Poor effort
3.4 == 3.4 Not attempted - Language
3.5 == 3.5 Not attempted - Illness
3.6 == 3.6 Not attempted - Logistical
4.0 == 4.0 Not attempted - Examiner error
5.0 == 5.0 Other
Outcomes.TMTDate
Outcomes.TMTHandedness 1 == Dominant
2 == Non-Dominant
This variable reflects if the patient used his dominant or non-dominant hand to perform the test
Outcomes.TMTNeuroPsychCompCode 1.0 == 1.0 Test not done
2.0 == 2.0 Test attempted but not completed
3.0 == 3.0 Test completed
Outcomes.TMTPartATime
Outcomes.TMTPartBTime
Outcomes.TMTTestAttemptdNotCompOptions 2.1 == Not completed - Cognitive/neurological deficits
2.2 == Not completed - Non-neurological/physical reason
2.3 == Not completed - Lack of effort/uncooperative
2.4 == Not completed - Language
2.5 == Not completed - Illness/fatigue
2.6 == Not completed - Logistical reasons, other reasons
2.7 == Not completed - Examiner error
Outcomes.TMTTestAttemptdNotCompOptionsOTHER
Outcomes.TMTTestCompletedOptions 3.0 == Test completed in full - results valid
3.1 == Test completed - Non-standard, results valid
3.2 == Non-standard administration - Other
Outcomes.TMTTestComplNonStandAdminOTHER
Outcomes.TMTTestNotDoneOptions 1.1 == Not attempted - Cognitive/neurological deficits
1.2 == Not attempted - Non-neurological/physical reasons
1.3 == Not attempted - Lack of effort/uncooperative
1.4 == Not attempted - Language
1.5 == Not attempted - Illness/fatigue
1.6 == Not attempted - Logistical reasons, other reasons
1.7 == Not attempted - Examiner error
1.8 == Not attempted - Patient not available
This variable needs to be completed when TMT completion code is set to 1.0 Test not done.
Outcomes.TMTTestNotDoneOptionsOTHER
Outcomes.TUGDate
Outcomes.TUGTimedResult Interpretation: < 10 sec = normal; < 20 sec: good mobility, can go out alone, mobile without gait aid; < 30 sec: problems, cannot go outside alone, requires a gait aid
PriorMeds.PmMedicalCode Medical History of patients has been recorded under MedHx.MedHx* A number of predefined medical conditions were coded in the e-CRF. If the patient was taking medication for this predefined medical condition, the same code needed to be entered here. An option other was also available for conditions not listed. Please check MedHx.MedHx* for the information on the medical condition(s) corresponding to this variable.
PriorMeds.PmMedicationName These fields capture information on medication taken pre-injury. For each medication taken, the corresponding Medical History code is listed to document the reason for which this med was taken. If the medication taken was not linked to one of the recorded medication history codes, Investigators were asked to enter "777" as related history code.
Registry.AbdomenPelvicContentsAIS 0
1
2
3
4
5
6
Registry.AbdomenPelvicContentsISS
Registry.AbdomenPelvicLumbarRegionAIS
Registry.Age Recorded in years.
Registry.Anticoagulants 0 = No
1 = Yes
88 = Unknown
Registry.BrainInjuryAIS 0
1
2
3
4
5
6
Registry.BrainInjuryISS
Registry.CervicalSpineAIS 0
1
2
3
4
5
6
Registry.CervicalSpineISS
Registry.ChestSpineRegionAIS
Registry.CraniotomyForHaematoma
Registry.CraniotomyForHaematomaDate
Registry.CraniotomyForHaematomaDateTime Calculated from Registry.CraniotomyForHaematomaDate and Registry.CraniotomyForHaematomaTime
Registry.CraniotomyForHaematomaTime
Registry.CT1Date Date of the first Brain CT
Registry.CT1DateTime Calculated value from Registry.CT1Date and Registry.CT1Time
Registry.CT1Time Time of the first Brain CT
Registry.CT1TimeSinceInj Calculated value from Registry.CT1Date, Registry.CT1Time and Registry.DateInj, Registry.TimeInj
Registry.CTAbnormalBasalCisterns 1 = Open
2 = Compressed/obliterated
88 = Unknown
These details record the investigators score of the first CT brain.
Registry.CTIntracranialLesions 0 = No
1 = Yes
88 = Unknown
These details record the investigators score of the first or subsequent CT brain scans as to whether or not TBI or intracranial bleeding is visible.
Registry.CTIntracranialLesionsPresentASDH 0 = No
1 = Small
2 = Large (mass)
88 = Unknown
These details record the investigators score of the first CT brain.
Registry.CTIntracranialLesionsPresentContusions 0 = No
1 = Small
2 = Large (mass)
88 = Unknown
These details record the investigators score of the first CT brain.
Registry.CTIntracranialLesionsPresentEDH 0 = No
1 = Small
2 = Large (mass)
88 = Unknown
These details record the investigators score of the first CT brain.
Registry.CTResult 0 = Normal
1 = Abnormal
These details record the investigators score of the first CT brain.
Registry.CTShift 0 = No
1 = 0-4mm
2 = ≥5mm
88 = Unknown
These details record the investigators score of the first CT brain.
Registry.CTtSAH 0 = No
1 = Yes
88 = Unknown
These details record the investigators score of the first CT brain.
Registry.DamageControlLaparotomy
Registry.DamageControlLaparotomyDate
Registry.DamageControlLaparotomyDateTime Calculated from Registry.DamageControlLaparotomyDate and Registry.DamageControlLaparotomyTime
Registry.DamageControlLaparotomyTime
Registry.DamageControlThoracotomy
Registry.DamageControlThoracotomyDate
Registry.DamageControlThoracotomyDateTime Calculated from Registry.DamageControlThoracotomyDate and Registry.DamageControlThoracotomyTime
Registry.DamageControlThoracotomyTime
Registry.DateInj
Registry.DateTimeInj
Registry.DateTimeInjReliable 1 = Verified
2 = Estimate
This variable documents if the time of injury is accurate, or is based on "best possible estimate", in case exact time of injury not known.
Registry.DayInjury 0 == Sunday
1 == Monday
2 == Tuesday
3 == Wednesday
4 == Thursday
5 == Friday
6 == Saturday
Day of injury. (Sunday - Saturday)
Registry.DeathCause 1 = Head injury/initial injury
2 = Head injury/secondary intracranial damage
3 = Systemic trauma
4 = Medical complications
88 = Unknown
99 = Other
Principle cause of death
Registry.DeathDate
Registry.DeathDateTime Calculated from Registry.DeathDate and Registry.DeathTime
Registry.DeathTime Time of death
Registry.DeathTimeSinceInj
Registry.DecompressionCraniectomy
Registry.DecompressionCraniectomyDate
Registry.DecompressionCraniectomyDateTime
Registry.DecompressionCraniectomyTime
Registry.DischargeDate
Registry.DischargeDateTime
Registry.DischargeDestination 1=Discharged to other hospital
2=Discharged to rehabilitation
3=Discharged to nursing home
5=Discharged to home with carer
6=Discharged to home and self-care but judged unfit for work
7=Discharged to home and self-care without reservations
8=Discharged to home and self-care with some reservations
88= Unknown
Documents destination upon hospital discharge
Registry.DischargeTime
Registry.EDArrDBP
Registry.EDArrivalBloodPressureUnknown
Registry.EDArrivalOxygenSatUnknown
Registry.EDArrivedIntubated This variable should have been checked if the patient already arrived intubated.
Registry.EDArrPupilLftEyeMeasr
Registry.EDArrPupilLftEyeMeasrUnkUnt 66 = Untestable
88 = Unknown
Registry.EDArrPupilRtEyeMeasr
Registry.EDArrPupilRtEyeMeasrUnkUnt 66 = Untestable
88 = Unknown
Registry.EDArrSBP
Registry.EDArrSpO2
Registry.EDCTBrain 0 = No
1 = Yes
88 = Unknown
Indication for CT was an inclusion criterium for the Core study - thus, nearly all patients in Core will have had a CT brain.
Registry.EDIntubation 0 = No
1 = Yes
88 = Unknown
Registry.EnrollDate Records the date of enrollment to the Registry Data Collection.
Registry.ExternaAIS 0
1
2
3
4
5
6
Registry.ExternaISS
Registry.ExternalFixationLimb
Registry.ExternalFixationLimbDate
Registry.ExternalFixationLimbDateTime Calculated from Registry.ExternalFixationLimbDate and Registry.ExternalFixationLimbTime
Registry.ExternalFixationLimbTime
Registry.ExternalVentricularCSFDrainage
Registry.ExternalVentricularCSFDrainageDate
Registry.ExternalVentricularCSFDrainageDateTime Calculated from Registry.ExternalVentricularCSFDrainageDate and Registry.ExternalVentricularCSFDrainageTime
Registry.ExternalVentricularCSFDrainageTime
Registry.ExternaRegionAIS
Registry.ExtraperitonealPelvicPacking
Registry.ExtraperitonealPelvicPackingDate
Registry.ExtraperitonealPelvicPackingDateTime Calculated from Registry.ExtraperitonealPelvicPackingDate and Registry.ExtraperitonealPelvicPackingTime
Registry.ExtraperitonealPelvicPackingTime
Registry.ExtremitiesRegionAIS
Registry.FaceAIS 0
1
2
3
4
5
6
Registry.FaceISS
Registry.FaceRegionAIS
Registry.GcsEDArrEyes 1 = 1-None
2 = 2-To pain
3 = 3-To speech
4 = 4-Spontaneously
S = Untestable (swollen)
O = Untestable (other)
UN = Unknown
In the Core data,the initial GCS and pupillary reactivity can be scored at 4 pre-defined moments in the pre-hospital/presentation phase: 1.: scene of accident; 2: first hospital (in case of secondary regerral; 3.: arrival to Er of study hospital; 4.: post-stabilization; In addition, assessment at a different time point is possible (designated as other). A derived variable captures the highest available GCS score across these time periods.
Registry.GcsEDArrMotor 1 = 1-None
2 = 2-Abnormal extension
3 = 3-Abnormal flexion
4 = 4-Normal flexion/withdrawal
5 = 5-Localizes to pain
6 = 6-Obeys command
P = Untestable (Deep sedation/paralyzed)
O = untestable (other)
Un = Unknown
Registry.GcsEDArrPupils 0 = None reacting
1 = One reacting
2 = Both reacting
Registry.GcsEDArrScore score by investigators in case component scores not available, but GCS sum score available
Registry.GcsEDArrVerbal 1 = 1-None
2 = 2-Incomprehensible sound
3 = 3-Inappropriate words
4 = 4-Confused
5 = 5-Oriented
T = Untestable (Tracheotomy/endotracheal tube)
O = Untestable (other)
Un = Unknown
Registry.HeadBrainCervicalRegionAIS
Registry.HeadNeckAIS 0
1
2
3
4
5
6
Injuries and their severity are recorded according to a (modification of) the AIS. The AIS recognizes 6 main body regions. We included a further subdivision for some body regions, resulting in a total of 12 regions. For example, spine is not considered separately in the original AIS classification, but included under neck/chest and abdomen regions. For TBI, however, we considered it important to record spine separately.
Registry.HeadNeckISS
Registry.HospitalAdm 0 = No
1 = Yes
88 = Unknown
Registry.ICPDeviceInsertion
Registry.ICPDeviceInsertionDate
Registry.ICPDeviceInsertionDateTime Calculated from Registry.ICPDeviceInsertionDate and Registry.ICPDeviceInsertionTime
Registry.ICPDeviceInsertionTime
Registry.ICUAdm 0 = No
1 = Yes
88 = Unknown
Registry.ICUAdmDate
Registry.ICUAdmDateTime Calculated from Registry.ICUAdmDate and Registry.ICUAdmTime
Registry.ICUAdmTime
Registry.ICUAdmTimeSinceInj
Registry.ICUDischDate
Registry.ICUDischDateTime Calculated from Registry.ICUDischDate and Registry.ICUDischTime
Registry.ICUDischTime
Registry.ICUDishcTimeSinceInj
Registry.InjMech 1 = RTA Pedestrian
2 = RTA Cyclist
3 = RTA Motorcyclist
4 = RTA Driver
5 = RTA Other vehicle occupant
6 = Fall standing height
7 = Fall from height
8 = Assault fists
9 = Assault blunt instrument
10 = Assault knife
11 = Assault firearm
12 = Self Harm
13 = Sport/recreational activity
14 = Other, please specify
99 = Other violence
88 = Unknown
Registry.InjPlace 1 = Street/traffic
2 = Home
3 = Work
4 = Sports field/hall
6 = Public place
99 = Other
88 = Unknown
Registry.InjType 1 = Blunt/closed
2 = Blast
3 = Crush
4 = Penetrating
88 = Unknown
Registry.InterventionalRadiology
Registry.InterventionalRadiologyDate
Registry.InterventionalRadiologyDateTime Calculated from Registry.InterventionalRadiologyDate and Registry.InterventionalRadiologyTime
Registry.InterventionalRadiologyTime
Registry.InterventionsOther
Registry.InterventionsOtherDate
Registry.InterventionsOtherDateTime Calculated from Registry.InterventionsOtherDate and Registry.InterventionsOtherTime
Registry.InterventionsOtherTime
Registry.KeyEmergencyInterventions 0 = No
1 = Yes
88 = Unknown
Registry.LowerExtremitiesAIS 0
1
2
3
4
5
6
Registry.LowerExtremitiesISS
Registry.LumbarSpineAIS 0
1
2
3
4
5
6
Registry.LumbarSpineISS
Registry.MonthInjury 1 == January
2 == February
3 == March
4 == April
5 == May
6 == June
7 == July
8 == August
9 == September
10 == October
11 == November
12 == December
Month of Injury (January - December)
Registry.PatientType 1 == ER
2 == Admission
3 == ICU
Stratum coded from ICUAdm, ERAdm, HospitalAdm
Registry.PelvicGirdleAIS 0
1
2
3
4
5
6
Registry.PelvicGirdleISS
Registry.PlateletAggregInhibitors 0 = No
1 = Yes
88 = Unknown
Registry.PreInjuryASAPSClassification 1 = A normal healthy patient
2 = A patient with mild systemic disease
3 = A patient with severe systemic disease
4 = A patient with severe systemic disease that is a constant threat to life
88 = Unknown
Common classification system used in anaesthesia; denotes overall health
Registry.PresCTBrain 0 = No
1 = Yes
88 = Unknown
only applicable in case of secondary referral. Procedure performed at first hospital (not study hospital).
Registry.PresEmergencyCare 0 = No professional care
1 = Ambulance service (no physician)
2 = Helicopter service
3 = Medical mobile team
98 = N/A (for example injury in hospital)
Registry.PresEmergencyCareIntubation 0 = No
1 = Yes
88 = Unknown
Registry.PresEmergencyCareVentilation 0 = No
1 = Yes
88 = Unknown
Registry.PresERExtracranialSurg 0 = No
1 = Yes
88 = Unknown
only applicable in case of secondary referral. Procedure performed at first hospital (not study hospital).
Registry.PresERIntracranialSurg 0 = No
1 = Yes
88 = Unknown
only applicable in case of secondary referral. Procedure performed at first hospital (not study hospital).
Registry.PresFHospDate First hospital is defined as the initial hospital to which the patient was brought before being transferred to Study hospital. Consequently, only applicable in case of secondary transferral. However, in some sites data for first hospital may have been entered also when the patient was brought directly to the study hospital.
Registry.PresFHospDateTime Calculated from Registry.PresFHospDate and Registry.PresFHospTime
Registry.PresFHospTime only applicable in case of secondary referral
Registry.PresFHospTimeSinceInj
Registry.PresIntubation 0 = No
1 = Yes
88 = Unknown
only applicable in case of secondary referral. Procedure performed at first hospital (not study hospital).
Registry.PresSTHospDate
Registry.PresSTHospDateTime Calculated from Registry.PresSTHospDate and Registry.PresSTHospTime
Registry.PresSTHospTime
Registry.PresSTHospTimeSinceInj
Registry.PresTBIRef 1 = Primary referral
2 = Secondary referral from other hospital
Registry.RegistryCompleteStatus
Registry.Sex M = Male
F = Female
The difference between male and female, based upon the interactions between genes and between the genotype and the environment. Gender of Subject.
Registry.SiteCode
Registry.StatusOnDischarge 0 = Dead
1 = Alive
Assessment by investigator
Registry.ThoracicSpineAIS 0
1
2
3
4
5
6
Registry.ThoracicSpineISS
Registry.ThoraxChestAIS 0
1
2
3
4
5
6
Registry.ThoraxChestISS
Registry.TimeInj
Registry.TotalISS 0
1
2
3
4
5
6
Represents the quadratic sum of the three AIS regions with the highest score.
Registry.UpperExtremitiesAIS 0
1
2
3
4
5
6
Registry.UpperExtremitiesISS
Registry.WardAdm 0 = No
1 = Yes
88 = Unknown
The intent here was to record direct admission to the ward versus direct admission to the ICU (Registry.ICUAdm). However, the possibility that this variable was also checked for patients discharged from the ICU to the Ward cannot be excluded.
Registry.WardAdmDate
Registry.WardAdmDateTime Calculated from Registry.WardAdmDate and Registry.WardAdmTime
Registry.WardAdmTime
Registry.WardAdmTimeSinceInj
Subject.Age Age in years
Subject.AnytimeGOSECompleteStatus
Subject.AnytimeGOSEDate
Subject.AnytimeGOSEMethod
Subject.AnytimeGOSEPtAlive
Subject.AnytimeGOSEScore
Subject.ApptPtShowOutcomes12Mo 0 == No
1 == Yes
77 == N/A
Subject.ApptPtShowOutcomes24mo 0 == No
1 == Yes
Subject.ApptPtShowOutcomes2Wk 0 == No
1 == Yes
77 == N/A
Subject.ApptPtShowOutcomes3Mo 0 == No
1 == Yes
77 == N/A
Subject.ApptPtShowOutcomes6Mo 0 == No
1 == Yes
77 == N/A
Subject.ApptQuestComplOutcomes12Mo 0 == No
1 == Yes
77 == N/A
Subject.ApptQuestComplOutcomes24Mo 0 == No
1 == Yes
77 == N/A
Subject.ApptQuestComplOutcomes2Wk 0 == No
1 == Yes
77 == N/A
Subject.ApptQuestComplOutcomes3Mo 0 == No
1 == Yes
77 == N/A
Subject.ApptQuestComplOutcomes6Mo 0 == No
1 == Yes
77 == N/A
Subject.ApptQuestLangUsed12Mo SWE == Swedish
ARA == Arabic
HEB == Hebrew
RUS == Russian
SPA == Spanish
SLO == Slovakian
SER == Serbian
ROM == Romanian
NOR == Norwegian
LIT == Lithuanian
ITA == Italian
HUN == Hungarian
FIN == Finnish
DAN == Danish
DUT == Dutch
FRE == French
GER == German
ENG == English
Subject.ApptQuestLangUsed24Mo SWE == Swedish
ARA == Arabic
HEB == Hebrew
RUS == Russian
SPA == Spanish
SLO == Slovakian
SER == Serbian
ROM == Romanian
NOR == Norwegian
LIT == Lithuanian
ITA == Italian
HUN == Hungarian
FIN == Finnish
DAN == Danish
DUT == Dutch
FRE == French
GER == German
ENG == English
Subject.ApptQuestLangUsed2Wk SWE == Swedish
ARA == Arabic
HEB == Hebrew
RUS == Russian
SPA == Spanish
SLO == Slovakian
SER == Serbian
ROM == Romanian
NOR == Norwegian
LIT == Lithuanian
ITA == Italian
HUN == Hungarian
GER == German
FIN == Finnish
DAN == Danish
FRE == French
DUT == Dutch
ENG == English
Subject.ApptQuestLangUsed3Mo SWE == Swedish
ARA == Arabic
HEB == Hebrew
RUS == Russian
SPA == Spanish
SLO == Slovakian
SER == Serbian
ROM == Romanian
NOR == Norwegian
LIT == Lithuanian
ITA == Italian
HUN == Hungarian
FIN == Finnish
DAN == Danish
DUT == Dutch
FRE == French
GER == German
ENG == English
Subject.ApptQuestLangUsed6Mo SWE == Swedish
ARA == Arabic
HEB == Hebrew
RUS == Russian
SPA == Spanish
SLO == Slovakian
SER == Serbian
ROM == Romanian
NOR == Norwegian
LIT == Lithuanian
ITA == Italian
HUN == Hungarian
FIN == Finnish
DAN == Danish
DUT == Dutch
FRE == French
GER == German
ENG == English
Subject.ApptQuestLocLang12Mo 0 == No
1 == Yes
99 == Unknown
Subject.ApptQuestLocLang24Mo 0 == No
1 == Yes
99 == Unknown
Subject.ApptQuestLocLang2Wk 0 == No
1 == Yes
99 == Unknown
Subject.ApptQuestLocLang3Mo 0 == No
1 == Yes
99 == Unknown
Subject.ApptQuestLocLang6Mo 0 == No
1 == Yes
99 == Unknown
Subject.ApptScheduledDateOutcomes12mo Milestone Window: 12month outcomes must be completed 10 - 14 months from DOI.
Subject.ApptScheduledDateOutcomes24mo Milestone Window: 24month outcomes must be completed 22 - 28 months from DOI
Subject.ApptScheduledDateOutcomes2wk Milestone window: 2week outcomes must be completed 10 - 27 days from DOI (Date Of Injury)
Subject.ApptScheduledDateOutcomes3mo Milestone Window: 3month outcomes must be completed 11 - 18 weeks from DOI (Date of Injury).
Subject.ApptScheduledDateOutcomes6mo Milestone Window: 6month outcomes must be completed 5 - 8 months from DOI (Date of Injury).
Subject.ApptScheduledTimeOutcomes12mo
Subject.ApptScheduledTimeOutcomes24mo
Subject.ApptScheduledTimeOutcomes2wk
Subject.ApptScheduledTimeOutcomes3mo
Subject.ApptScheduledTimeOutcomes6mo
Subject.ApptTargetDateOutcomes12Mo The variables on the forms follow-up appointments document the prefered appointment date, the actually scheduled date and time and provide general informatoin if the patient completed the follow-up or not. Forms are available for all possible follow-up moments, please note that not all these times may be applicable, for example the details for 24 months outcome would only apply to patients in the ICU stratum who underwent MR imaging
Subject.ApptTargetDateOutcomes24mo The variables on the forms follow-up appointments document the prefered appointment date, the actually scheduled date and time and provide general informatoin if the patient completed the follow-up or not. Forms are available for all possible follow-up moments, please note that not all these times may be applicable, for example the details for 24 months outcome would only apply to patients in the ICU stratum who underwent MR imaging
Subject.ApptTargetDateOutcomes2Wk The variables on the forms follow-up appointments document the prefered appointment date, the actually scheduled date and time and provide general informatoin if the patient completed the follow-up or not. Forms are available for all possible follow-up moments, please note that not all these times may be applicable, for example the details for 24 months outcome would only apply to patients in the ICU stratum who underwent MR imaging
Subject.ApptTargetDateOutcomes3Mo The variables on the forms follow-up appointments document the prefered appointment date, the actually scheduled date and time and provide general informatoin if the patient completed the follow-up or not. Forms are available for all possible follow-up moments, please note that not all these times may be applicable, for example the details for 24 months outcome would only apply to patients in the ICU stratum who underwent MR imaging
Subject.ApptTargetDateOutcomes6Mo The variables on the forms follow-up appointments document the prefered appointment date, the actually scheduled date and time and provide general informatoin if the patient completed the follow-up or not. Forms are available for all possible follow-up moments, please note that not all these times may be applicable, for example the details for 24 months outcome would only apply to patients in the ICU stratum who underwent MR imaging
Subject.AssociatedStudy 1 == RESCUE-ASDH
2 == TAHITI-B
3 == PROLABI
Documents if a subject was enrolled in an associated CENTER-TBI study: RESCUE ASDH/Tahiti/Prolabi
Subject.Comments
Subject.ConsentWithdrawn
Subject.ConsentWithdrawnDate
Subject.ConsentWithdrawnReason WHY Question: documents the reason for withdrawing subject
Subject.ConsentWithdrawnTime
Subject.DateInj Date of Injury. Anonymised and saved as 1970-01-01 for all patients. All other dates are converted relative to date of Injury.
Subject.DateOfAdmission This variable denotes date of admission to hospital; Therefore not applicable to subjects in ER stratum. In principle the date of injury; date of enrollment and Date of Admission to ICU or Ward will match, but in some cases there can be a difference of 1 or 2 days. For example when a patient was injured late at night, it is possible that the consent was only obtained in the morning, hence the date of Study Enrollment will be 1 day later than the date of injury. Or in some hospitals a patient is kept for 24 hours in observation at the ER in a specific unit before being transferred to ICU or Ward. Hence the Date of Admission to ICU or Ward can be 1 or 2 days later. Or if there is no bed available on ICU or Ward for a patient being injured late at night, there can be a delay in admitting the patient. Also, in some countries, Enrollment Date > 24h was accepted according to local regulations and IRB.
Subject.DateTimeInjReliable 1 == Verified
2 == Estimated
This variable documents if the time of injury is accurate, or is based on "best possible estimate", in case exact time of injury not known.
Subject.DayInjury 0 == Sunday
1 == Monday
2 == Tuesday
3 == Wednesday
4 == Thursday
5 == Friday
6 == Saturday
Day of injury. (Sunday - Saturday)
Subject.DeathCause 1 == Head injury/initial injury
2 == Head injury/secondary intracranial damage
3 == Systemic trauma
4 == Medical complications
88 == Unknown
99 == Other
Cause of death in or outside the hospital
Subject.DeathCauseOther
Subject.DeathDate Date of death also recorded on hospital discharge and at followup: FollowUp.FUPrincipalDeathCause;Death may also have been recorded in the ER forms: Subject.DeathDate
Subject.DeathERDeclaredBrainDeadFollowingNationalCriteria 0 == No
1 == Yes
88 == Unknown
Only applicable if patient declared "dead" on the ER
Subject.DeathERDOA 0 == No
1 == Yes
88 == Unknown
Only applicable if patient declared "dead" on the ER
Subject.DeathERUnsuccResusForExtraCranInj 0 == No
1 == Yes
88 == Unknown
Only applicable if patient declared "dead" on the ER
Subject.DeathERWithdrawalLifeSuppForSeverityOfTBI 0 == No
1 == Yes
88 == Unknown
Only applicable if patient declared "dead" on the ER
Subject.DeathTime Time of death
Subject.DerivedImputed180DaysGOSE “1”= Dead
“2_or_3”= VS / Lower Severe Disability
“4”= Upper Severe Disability
“5” = Lower Moderate Disability
“6” = Upper Moderate Disability
“7” = Lower Good Recovery
“8” =Upper Good Recovery
This variable contains a GOSE that has been imputed at exactly 180 days after injury. Imputation is based on the composite GOSE recorded at different timepoints 2 weeks to one year. The imputation of the GOSE uses a multi-state model. The model does not include any baseline covariates. Since the imputation uses GOSE information across time points, the imputed 6 month GOSE does not necessarily correspond to outcomes that are observed at 6 months. Apart from deaths, imputed values of the GOSE are subject to uncertainty, and this is reflected in the companion variables that give the probabilities that a given outcome is in each of the GOSE categories 1 to 8. (Subject.DerivedImputed180DaysGOSE_1_probability, Subject.DerivedImputed180DaysGOSE_2_3_probability, Subject.DerivedImputed180DaysGOSE_4_probability, Subject.DerivedImputed180DaysGOSE_5_probability, Subject.DerivedImputed180DaysGOSE_6_probability, Subject.DerivedImputed180DaysGOSE_7_probability, Subject.DerivedImputed180DaysGOSE_8_probability). The category with the highest probability is taken as the final imputed value. Deaths have been added to this variable where a date of death is recorded on or before 180 days. The GOSE is a character/ string variable (not numeric) with the following categories: “1”= Dead, “2_or_3”= VS / Lower Severe Disability, “4”= Upper Severe Disability, “5” = Lower Moderate Disability, “6” = Upper Moderate Disability, “7” = Lower Good Recovery, “8” =Upper Good Recovery.
Subject.DerivedImputed180DaysGOSE_1_probability See "Subject.DerivedImputed180DaysGOSE"
Subject.DerivedImputed180DaysGOSE_2_or_3_probability
Subject.DerivedImputed180DaysGOSE_2_probability See "Subject.DerivedImputed180DaysGOSE"
Subject.DerivedImputed180DaysGOSE_3_probability See "Subject.DerivedImputed180DaysGOSE"
Subject.DerivedImputed180DaysGOSE_4_probability See "Subject.DerivedImputed180DaysGOSE"
Subject.DerivedImputed180DaysGOSE_5_probability See "Subject.DerivedImputed180DaysGOSE"
Subject.DerivedImputed180DaysGOSE_6_probability See "Subject.DerivedImputed180DaysGOSE"
Subject.DerivedImputed180DaysGOSE_7_probability See "Subject.DerivedImputed180DaysGOSE"
Subject.DerivedImputed180DaysGOSE_8_probability See "Subject.DerivedImputed180DaysGOSE"
Subject.DNRDateTime
Subject.EduLvlEUROFather 0 == None, not currently in school
1 == Currently in diploma or degree-oriented program
2 == Primary school
3 == Secondary school / High school
4 == Post-high school training (e.g. trade/technical certificate)
5 == College / University (diploma or degree)
88 == Unknown
Only if age <18
Subject.EduLvlEUROMother 0 == None
not currently in school
1 == Currently in diploma or degree-oriented program
2 == Primary school
3 == Secondary school / High school
4 == Post-high school training (e.g. trade/technical certificate)
5 == College / University (diploma or degree)
88 == Unknown
Only if age <18
Subject.EduLvlUSATyp 0 == None, not currently in school
1 == Currently in diploma or degree-oriented program
2 == Primary school
3 == Secondary school / High school
4 == Post-high school training (e.g. trade/technical certificate)
5 == College / University (diploma or degree)
88 == Unknown
Subject.EduYrCt Number of years of education completed
Subject.EmplmtStatus 1 == Working (35 hours or more per week)
2 == Working (20-34 hours per week)
3 == Working (less than 20 hours per week)
4 == In working force, but currently on sick leave
5 == Special employment / sheltered employment
6 == Looking for work, unemployed
7 == Unable to work
8 == Retired
9 == Student / schoolgoing
10 == Homemaker, keeping house
88 == Unknown
Subject.EnrollDate Date of Study Enrollment. In principle the date of injury and date of enrollment will match, but in some cases there can be a difference of 1 or 2 days. For example when a patient was injured late at night, it is possible that the consent was only obtained in the morning, hence the date of Study Enrollment will be 1 day later than the date of injury.
Subject.EnrolledInOtherStudy 0 == No
1 == Yes
99 == Unknown
Denotes if a subject was also enrolled in a concomitant study
Subject.EOSDate
Subject.EOSFormCompletion 0 == No
1 == Yes
Subject.EOSFormNotCompleteOtherReasonTxt
Subject.EOSFormNotCompletePrimReason 1 == Consent withdrawn
2 == Violation study conduct
99 == Other
Subject.EOSFormNotCompleteViolateStudyConductTxt
Subject.EOSReason 1 == Completion of study
2 == Inability to obtain follow-up
3 == Withdrawal from study (by patient or representative)
4 == Adverse event(s)
5 == Decision for DNR*:
6 == Withdrawal of support
7 == Death
99 == Other
Subject.EOSReasonOtherTxt
Subject.FUConsentForContStudyPart This variable documents written consent obtained from the patient for continued study participation
Subject.FUConsentForContStudyPartDate
Subject.GOSE6monthEndpointDerived “1”= Dead
“2_or_3”= VS / Lower Severe Disability
“4”= Upper Severe Disability
“5” = Lower Moderate Disability
“6” = Upper Moderate Disability
“7” = Lower Good Recovery
“8” =Upper Good Recovery.
A six month GOSE endpoint that uses both observed ratings and imputed values. The variable is constructed as follows: (1) “Dead” is recorded for those with a date of death on or before 180 days post injury. (2) If there is an observed GOSE in the range 150 to 240 days (i.e. in the per protocol time window for six month assessment) then this rating is used. (3) If there is no per-protocol rating, then then an imputed 180 day GOSE is used where available. For a description of the imputation method see the variable ‘Subject.DerivedImputed180DaysGOSE’. The GOSE is a character/ string variable (not numeric) with the following categories: “1”= Dead, “2_or_3”= VS / Lower Severe Disability, “4”= Upper Severe Disability, “5” = Lower Moderate Disability, “6” = Upper Moderate Disability, “7” = Lower Good Recovery, “8” =Upper Good Recovery.
Subject.GOSE6month_probability_1 Superseded variable.
Subject.GOSE6month_probability_2 Superseded variable
Subject.GOSE6month_probability_3 Superseded variable
Subject.GOSE6month_probability_4 Superseded variable
Subject.GOSE6month_probability_5 Superseded variable
Subject.GOSE6month_probability_6 Superseded variable
Subject.GOSE6month_probability_7 Superseded variable
Subject.GOSE6month_probability_8 Superseded variable
Subject.GUPI The Global Unique Patient Identifier (GUPI) is a unique identifier that meets protection requirements in the EU and in Member States. This process takes patient specific characteristics (such as the first name, middle name, last name, place of birth, country of birth, date of birth, and gender) to generate a unique GUPI for each patient using an irreversible process, referred to as a “one way hash”. This process replicates an approach taken by the Federal Inter-agency Traumatic Brain Injury Research initiative (FITBIR; https://fitbir.nih.gov/) in the USA to create a similar construct, which they term a Global Unique Identifier (GUID; see https://fitbir.nih.gov/jsp/contribute/guid-overview.jsp). This process is one of the options considered by rulings on EU Data Protection requirements at the start of the study (see http://ec.europa.eu/justice/data-protection/article-29/documentation/opinion-recommendation/files/2014/wp216_en.pdf).
Subject.InfConsBy 1 == Doctor (MD)
2 == Nurse
4 == Research assistant
99 == Other
Type of health care professional who requested and obtained consent
Subject.InfConsDate Confirmation of consent date; denotes written confirmation
Subject.InfConsentBlood
Subject.InfConsentData Explicit consent was requested for broad use and possible transfer of clinical data, blood samples, genetics, MRI and outcome.
Subject.InfConsentDNA
Subject.InfConsentMRI
Subject.InfConsentOutcomeAssmts
Subject.InfConsInitialDate
Subject.InfConsInitialTime
Subject.InfConsTime Confirmation of consent time; denotes written confirmation
Subject.InfConsTyp 1 == Informed consent (by subject) oral
2 == Informed consent (by subject) written
3 == Proxy consent verbal
4 == Proxy consent written
5 == Deferred consent
6 == Waiver of consent
Designates the initial form of consent used
Subject.InfConsWhen 1 == Written proxy consent BEFORE enrolment
2 == Written proxy consent AFTER enrolment
3 == Written informed consent by patient
Subject.JobclassCat 0 == None
1 == Manager / Professional
2 == Technician / Supervisor / Associate Professional
3 == Clerk / Sales
4 == Skilled manual worker
5 == Manual worker
99 == Other
Only displayed if employment status is 1-4
Subject.JobclassCatOther
Subject.LengthOfStay This variable reflects the length of stay of the patient at the study hospital. It has been derived using the information of the date and time of arrival at the study hospital and date and time of (study) hospital discharge.
Subject.MartlPartnerStatus 1 == Never been married
2 == Married
3 == Living together/common law
4 == Divorced
5 == Separated
6 == Widowed
88 == Unknown
99 == Other
Subject.MonthInjury 1 == January
2 == February
3 == March
4 == April
5 == May
6 == June
7 == July
8 == August
9 == September
10 == October
11 == November
12 == December
Month of Injury (January - December)
Subject.ObservStudyOtherObservStudy
Subject.ObservStudyOtherRegistry
Subject.ObservStudyRegistry 1 == CREACTIVE
2 == TARN or EuroTARN registry
3 == German Trauma registry
4 == Net-QuRe
98 == Other Registry
99 == Other Observational Study
Specifies if subject is also enrolled in another observational study/registry
Subject.PatientType 1 == ER
2 == Admission
3 == ICU
Subjects enrolled in the Core data collection of CENTER are differentiated by stratum (3 strata): ER: discharged directly from ER (dead or alive); Adm: admitted to hospital ward from the ER (may be transferred later to ICU); ICU: directly admitted from ER (or other hospital) to ICU. Patients remain in the stratum allocated, even though they may be internally transferred after admission. This means that the stratum is allocated at presentation based on planned care paths. But possibility exists that a patient allocated to for example the ER stratum, was still admitted to WARD or ICU in a later stage of his care path due to worsening. General enrollment criteria for Core study: Patients with a clinical diagnosis of TBI and clinical indication for CT scan.
Subject.Race Race of Subject
Subject.RandomizedControlTrial 1 == CRASH-3
2 == EPO-TBI
3 == Eurotherm
4 == POLAR (Oxy-TC)
5 == NOSTRA
99 == Other Randomized Clinical Trial
This variables is to ask if the patient is enrolled in another randomized controlled trial
Subject.RandomizedControlTrialOther
Subject.SesEduNoFather Only if age <18
Subject.SesEduNoMother Only if age <18
Subject.SesNumberPeopleLivingWith Living together and number of people living with provides an indication of "social support" - important to recovery and social re-integration.
Subject.SESPrimAdultAlone
Subject.SESPrimAdultChildren
Subject.SESPrimAdultParents
Subject.SESPrimAdultSiblings
Subject.SESPrimAdultSignOther
Subject.SESPrimAdultSpousePartner
Subject.SESPrimAdultUnknown
Subject.Sex M == Male
F == Female
The difference between male and female, based upon the interactions between genes and between the genotype and the environment. Gender of Subject.
Subject.SiteCode
Subject.StudentStatus 0 == None
1 == Full time, diploma / degree oriented
2 == Part time, diploma / degree oriented
3 == Other school
88 == Unknown
Only displayed if employment status is student/school going
Subject.SurgeriesNotes
Subject.TimeInj If exact time of injury is unknown, Investigators were asked to approximate the closest time and code "estimation" in the following variable: Subject.DateTimeInjReliable
Subject.TransOfCareCompleteStatusNotes
Subject.ValidGUPI
Subject.WithdrawalOption 1 == Complete Withdrawal (no further contact, destruction of all data and samples collected up to that point)
2 == No further study related activities, but consent to access of clinical notes and use of existing data
In case of complete withdrawal, all data have been deleted from the database
Subject.WithdrawSuppDateTime
Surgeries.CranialSurgDone 0 == No
1 == Yes
88 == Unknown
These variables document cranial surgical procedures performed during the hospital stay. Up to 5 different surgical sessions can be recorded; Start date/time, stop date/time, reason for surgery and any delays in starting surgery are recorded. Life-saving emergency procedures performed immediately after presentation are recorded in the ER section: InjuryHx.EmergSurgInterventionsIntraCran. Procedures performed in "first" hospital (in case of secondary referral) are documented at: InjuryHx.PresERIntracranialSurg.
Surgeries.DecompressiveCran 0 == No
1 == Yes
These variables specifically focus on decompressive craniectomy (DC). Considerable uncertainty exists on which patients may benefit from DC, as well as on the timing. Previous studies have shown that in approximately one third of cases the DC was too small in size.
Surgeries.DecompressiveCranLocation 1 == Bifrontal
2 == Hemicraniectomy- left side
3 == Hemicraniectomy- right side
4 == Posterior fossa
Documents type of decompressive craniectomy.
Surgeries.DecompressiveCranReason 1 == Pre-emptive approach to treatment of (suspected) raised ICP (not last resort)
2 == Raised ICP, refractory to medical management (last resort)
3 == ICP not monitored, but CT evidence of raised ICP
4 == Not directly planned, but decided on because of intra-operative brain swelling
5 == Routinely performed with every ASDH or Contusion evacuation
6 == Development of cerebral infarction
WHY question: documents main reason for performing DC
Surgeries.DecompressiveCranType 1 == Isolated procedure
2 == In association with ASDH removal
3 == In association with contusion/ICH removal
4 == In association with ASDH and contusion/ICH removal
The indications for the decompressive craniectomy can be documented here.
Surgeries.DecompressiveSize In some sites, the size of DC was recorded by Investigators. No generable way of calculating was proposed.
Surgeries.ExtraCranialSurgDone 0 == No
1 == Yes
88 == Unknown
These variables document extracranial surgical procedures performed during the hospital stay. Up to 5 different surgical sessions can be recorded; Start date/time, stop date/time, reason for surgery and any delays in starting surgery are recorded. Life-saving emergency procedures performed immediately after presentation are recorded in the ER section: InjuryHx.EmergSurgInterventionsExtraCran. Procedures performed in "first" hospital (in case of secondary referral) are documented at: InjuryHx.PresERExtracranialSurg.
Surgeries.SurgIntervenAppro 0 == 0
1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
7 == 7
8 == 8
9 == 9
10 == 10
SurgeriesCranial.ShortTermSurvivalNoSurg These 2 variables aim to capture information on the surgeon's expectations, eg if the surgeon considers a realistic expectation of benefit, or performs the surgery as a "last resort" in a likely hopeless case.
SurgeriesCranial.ShortTermSurvivalYesSurg These 2 variables aim to capture information on the surgeon's expectations, eg if the surgeon considers a realistic expectation of benefit, or performs the surgery as a "last resort" in a likely hopeless case.
SurgeriesCranial.SurgeryCranialDelay 1 == Transferral from other hospital
2 == Haemodynamic instability
3 == No OR available
4 == Surgeon delayed
5 == No delay
99 == Other
SurgeriesCranial.SurgeryCranialReason 1 == Emergency/Life saving
2 == Clinical deterioration
3 == Mass effect on CT
4 == Radiological progression
5 == suspicion of) raised ICP
6 == Guideline adherence
7 == To prevent deterioration
WHY Question: aims to document the reason for intracranial surgery
SurgeriesCranial.SurgeryDescCranial 01 == Aneurysm (non trauma)
02 == Acute subdural hematoma
03 == Contusion
04 == Craniofacial surgery
05 == CSF shunt
06 == Chronic subdural hematoma
07 == Decompressive craniectomy-hemicraniectomy
08 == Depressed skull fracture
09 == Epidural hematoma
10 == Intracerebral hematoma
11 == Infection
12 == Optic nerve decompression
13 == Posterior fossa surgery
14 == Skull base fracture
15 == Ventriculostomy for CSF drainage
16 == Debridement -minimal for penetrating injuries
17 == Debridement - extensive for penetrating injuries
18 == Foreign body removal
19 == Bone flap replacement
20 == Cranioplasty
21 == Other
071 == Decompressive craniectomy - bifrontal
072 == Decompressive craniectomy - removal previous bone flap
Up to 3 different surgical codes can be entered per surgical session
SurgeriesCranial.SurgeryEndDate
SurgeriesCranial.SurgeryEndTime
SurgeriesCranial.SurgeryStartDate
SurgeriesCranial.SurgeryStartTime
SurgeriesExtraCranial.SurgeryDescExtraCranial 22 == Maxillofacial
23 == Extremity fracture lower limb (internal fixation)
24 == Extremity fracture lower limb (external fixation)
25 == Extremity fracture upper limb (internal fixation)
26 == Extremity fracture upper limb (external fixation)
27 == Fasciotomy
28 == Laparotomy (abdomen)
29 == Pelvic fracture (internal fixation)
30 == Pelvic fracture (external fixation)
31 == Spinal stabilisation/cervical
32 == Spinal stabilisation/thoracic
33 == Spinal stabilisation/lumbar
34 == Thoracotomy
35 == Tracheostomy
36 == Vascular (operative)
37 == Vascular (endovascular treatment)
38 == Wound closure/graft
39 == Other
SurgeriesExtraCranial.SurgeryEndDate
SurgeriesExtraCranial.SurgeryEndTime
SurgeriesExtraCranial.SurgeryExtraCranialDelay 1 == Transferral from other hospital
2 == Haemodynamic instability
3 == No OR available
4 == Surgeon delayed
5 == No Delay
99 == Other
SurgeriesExtraCranial.SurgeryExtraCranialReason 1 == Emergency/Lifesaving
2 == Elective
3 == Treatment of complication
4 == Airway management
99 == Other
SurgeriesExtraCranial.SurgeryStartDate
SurgeriesExtraCranial.SurgeryStartTime
TransitionsOfCare.CauseOfDelay 1 == Unavailability of beds in the receiving unit
2 == Unavailability of transport
3 == Wish of patient/proxies
4 == Need for isolation due to multi resistant bacteria
5 == Funding issues
6 == Bureaucratic causes
99 == Other
WHY question: documents reason for delayed transition of care
TransitionsOfCare.CauseOfDelayOther
TransitionsOfCare.DateClinReadyForTransfer This variable documents the date at which the patient is considered ready for transfer; the date of "effective" transfer documents the date to which this transfer actually occured. In case of a substantial difference, the cause of delay should be recorded
TransitionsOfCare.DateEffectiveTransfer
TransitionsOfCare.Location InHosp == In Hospital
PostDisch == Post Discharge
TransitionsOfCare.TransFrom RSHICU == Readmission Study Hosp - ICU
RSH == Readmission Study Hospital
SMCH == Substance misuse Care Unit
PSY == Psychiatric Unit
ER == ER
NH == Nursing Home
NSRU == Non-specialized rehab unit
SRU == Rehab Unit, specialized in Brain Injury
HOME == Home
IHR == In-hospital Rehab
MRI == MRI
CT == CT
OR == OR
ICU == ICU
WO == Ward - Other
WS == Ward - Surgery
WN == Ward - Neurology
WNS == Ward - Neurosurgery
HCU == High Care Unit
RU == Rehab Unit
98 == Other Hospital
99 == Other
This informs on the care pathway of the patient. It is important to also check the ER, ADM and/or ICU admission and discharge forms for information on the care pathway.
TransitionsOfCare.TransReason 1 == Mechanical ventilation
2 == Frequent neurological observations
3 == Haemodynamic invasive monitoring
4 == Extracranial injuries
5 == Neurological operation
6 == Clinical deterioration
7 == CT abnormalities
8 == Clinical observation for TBI
9 == No ICU bed available
10 == Could be discharged home, but no adequate supervision
11 == Improvement
12 == Neurological deterioration
13 == Systemic compilation
14 == CT progression
15 == Planned surgery
16 == Condition stable
17 == (acute) Treatment goals accomplished
18 == Need to free a bed
19 == Further improvement
20 == Clinical rehab completed
21 == Lack of improvement
22 == Late neurological deterioration
23 == Problems unrelated to trauma
24 == Post operative care
25 == Neurological complication
99 == Other
WHY question: documents reason for transition of care
TransitionsOfCare.TransTiming PRE == Premature
APP == Appropriate
DEL == Delayed
Transitions of care may be premature or delayed because of logistic problems. This variable aims to capture such information.
TransitionsOfCare.TransTo NSRU == Non-specialized rehab unit
SRU == Rehab Unit, specialized in Brain Injury
ER == ER
RSHICU == Readmission Study Hosp - ICU
RSH == Readmission Study Hospital
SMCH == Substance misuse Care Unit
PSY == Psychiatric Unit
NH == Nursing Home
RU == Rehab Unit
HOME == Home
IHR == In-hospital Rehab
MRI == MRI
CT == CT
OR == OR
ICU == ICU
WO == Ward - Other
WS == Ward - Surgery
WN == Ward - Neurology
WNS == Ward - Neurosurgery
HCU == High Care Unit
98 == Other Hospital
99 == Other
Vitals.DailyGCSTime For each Day of assessment, a Best and Worst score of GCS and pupillary reactivity is requested. If both scores are the same, only the Worst is reported.
Vitals.DVAssmtConditions 0 == No sedation or paralysis
1 == Sedated
2 == Paralyzed
3 == Temporary stop of sedation/paralysis
4 == Reversal of sedation/paralysis
5 == Active reversal (pharmacologic) of sedation/paralysis
99 == Other
Vitals.DVAssmtConditionsWorst 0 == No sedation or paralysis
1 == Sedated
2 == Paralyzed
3 == Temporary stop of sedation/paralysis
4 == Reversal of sedation/paralysis
5 == Active reversal (pharmacologic) of sedation/paralysis
99 == Other
Only applicable to ICU stratum
Vitals.DVBestPupilSymmetry 1 == Equal
2 == Unequal R>L
3 == Unequal L>R
The pupil are of equal size (symmetry) during the day
Vitals.DVBloodGasNotDone
Vitals.DVBloodOxySatHigh As determined from Arterial Blood Gas
Vitals.DVBloodOxySatHighNotDone As determined from Arterial Blood Gas
Vitals.DVBloodOxySatLow As determined from Arterial Blood Gas
Vitals.DVBloodOxySatLowNotDone As determined from Arterial Blood Gas
Vitals.DVBrainTempCLow Brain temperature at the timepoint of the lowest body temperature of the day, degrees Celsius.
Vitals.DVBrainTempLowNotDone
Vitals.DVBrainTempUnit C == C
F == F
Vitals.DVChangeCauseWorst 1 == Mainly intracranial
2 == Mainly extracranial
3 == Both to an equal extent
88 == Unknown
Vitals.DVChangeInOneDay 0 == No change
1 == Improving
2 == Episode of deterioration
3 == Sustained deterioration
4 == Fluctuating
Vitals.DVChangeInOneDayWorst 0 == No change
1 == Improving
2 == Episode of deterioration
3 == Sustained deterioration
4 == Fluctuating
Vitals.DVDate Daily vitals are documented in both the adm and ICU strata on Day 1-7, Day 10, Day 14, Day 21 and Day 28. Note: FOUR score only applicable to patients in the ICU.
Vitals.DVDBP The diastolic blood pressure at the timepoint of the highest systolic blood pressure.
Vitals.DVDBPLow The diastolic blood pressure at the timepoint of the lowest systolic blood pressure.
Vitals.DVFiO2AtHighPaO2
Vitals.DVFiO2AtHighPaO2NotDone
Vitals.DVFiO2AtLowPaO2
Vitals.DVFiO2AtLowPaO2NotDone
Vitals.DVFourScoreBraintstem 0 == Absent pupil, corneal, and cough reflex
1 == Pupil and corneal reflexes absent
2 == Pupil or corneal reflexes absent
3 == One pupil wide and fixed
4 == Pupil and corneal reflexes present
88 == Unknown
Vitals.DVFourScoreEye 0 == Eyelids remain closed with pain
1 == Eyelids closed but opens to pain
2 == Eyelids closed but opens to loud voice
3 == Eyelids open but not tracking
4 == Eyelids open or opened tracking or blinking to command
88 == Unknown
Vitals.DVFourScoreMotor 0 == No response to pain or generalized myoclonus status epilepticus
1 == Extensor posturing
2 == Flexion response to pain
3 == Localizing to pain
4 == Thumbs up, fist, or peace sign to command
88 == Unknown
Vitals.DVFourScoreNotDone
Vitals.DVFourScoreRespiration 0 == Breathes at ventilator rate or apnea
1 == Breathes above ventilator rate
2 == Not intubated, irregular breathing pattern
3 == Not intubated, Cheyne- Stokes breathing pattern
4 == Not intubated, regular breathing pattern
88 == Unknown
Vitals.DVFourScoreTotal DVFourScoreEye + DVFourScoreMotor + DVFourScoreBraintstem + DVFourScoreRespiration. No score if any of the components =88 (unknown) or NULL
Vitals.DVGCSBest 0 == No
1 == Yes
Vitals.DVGCSBestChangeCause 1 == Mainly intracranial
2 == Mainly extracranial
3 == Both to an equal extent
88 == Unknown
Vitals.DVGCSBestTime
Vitals.DVGCSEyes S == Untestable (swollen)
UN == Unknown
O == Untestable (Other)
1 == 1-None
2 == 2-To pain
3 == 3-To speech
4 == 4-Spontaneously
Vitals.DVGCSMotor O == Untestable (Other)
UN == Unknown
P == Untestable (Deep sedation/paralyzed)
1 == 1-None
2 == 2-Abnormal extension
3 == 3-Abnormal flexion
4 == 4-Normal flexion/withdrawal
5 == 5-Localizes to pain
6 == 6-Obeys command
Vitals.DVGCSPupilsNotDone
Vitals.DVGCSScore Best GCS Score: DVGCSEyes + DVGCSMotor + DVGCSVerbal. If one or more of these is Untestable or unknown then = "No Sum"
Vitals.DVGCSVerbal T == Untestable (Tracheotomy/endotracheal tube)
O == Untestable (Other)
UN == Unknown
1 == 1-None
2 == 2- Incomprehensible sound
3 == 3-Inappropriate words
4 == 4-Confused
5 == 5-Oriented
Vitals.DVGCSWorstEyes UNK == Unknown
O == Untestable (Other)
S == Untestable (swollen)
1 == 1-None
2 == 2-To pain
3 == 3-To speech
4 == 4-Spontaneously
Vitals.DVGCSWorstMotor UN == Unknown
O == Untestable (Other)
P == Untestable (Deep sedation/paralyzed)
1 == 1-None
2 == 2-Abnormal extension
3 == 3-Abnormal flexion
4 == 4-Normal flexion/withdrawal
5 == 5-Localizes to pain
6 == 6-Obeys command
Vitals.DVGCSWorstScore Worst GCS: DVGCSWorstEyes + DVGCSWorstMotor + DVGCSWorstVerbal. If one or more of these is Untestable or unknown then = "No Sum"
Vitals.DVGCSWorstVerbal O == Untestable (Other)
T == Untestable (Tracheotomy/endotracheal tube)
UN == Unknown
1 == 1-None
2 == 2- Incomprehensible sound
3 == 3-Inappropriate words
4 == 4-Confused
5 == 5-Oriented
Vitals.DVHighestPaCO2 Highest PaCO2 on a day, in mmHg.
Vitals.DVHighestPaCO2kPa The highest value of PaCO2 measured on each day, in kPa.
Vitals.DVHighestPaCO2NotDone
Vitals.DVHighestPaCO2Unit mmHg == mmHg
kPa == kPa
The unit in which the highest PaCO2 on a day is measured.
Vitals.DVHighestPaO2
Vitals.DVHighestPaO2kPa
Vitals.DVHighestPaO2NotDone
Vitals.DVHighestPaO2OverHighestFiO2
Vitals.DVHighestPaO2Unit mmHg == mmHg
kPa == kPa
Vitals.DVHighestpH
Vitals.DVHighestpHNotDone
Vitals.DVHR The highest heart rate during the day.
Vitals.DVHRHighTime The timepoint for the highest heart rate of a day.
Vitals.DVHRLow The lowest heart rate of a day.
Vitals.DVHRLowTime The time of the lowest heart rate of a day
Vitals.DVIntracranialSecondInsultsNotDone
Vitals.DVLowestPaCO2 The lowest value of PaCO2 measured on each day, in mmHg.
Vitals.DVLowestPaCO2kPa The lowest value of PaCO2 measured on each day, in kPa.
Vitals.DVLowestPaCO2NotDone
Vitals.DVLowestPaCO2Unit mmHg == mmHg
kPa == kPa
The unit in which PaCO2 is measured.
Vitals.DVLowestPaO2
Vitals.DVLowestPaO2kPa
Vitals.DVLowestPaO2NotDone
Vitals.DVLowestPaO2OverLowestFiO2
Vitals.DVLowestPaO2Unit mmHg == mmHg
kPa == kPa
Vitals.DVLowestpH
Vitals.DVLowestpHNotDone
Vitals.DVPupilLftEyeMeasr 1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
7 == 7
8 == 8
9 == 9
10 == 10
Vitals.DVPupilLftEyeMeasrUnkUnt 66 == Untestable
88 == Unknown
Only applicable to size
Vitals.DVPupilReactivityLghtLftEyeReslt 1 == + (Brisk)
2 == + (Sluggish)
3 == - (Negative)
The best pupillary reactivity of the left eye during the day
Vitals.DVPupilReactivityLghtRtEyeReslt 1 == + (Brisk)
2 == + (Sluggish)
3 == - (Negative)
Best pupillary reactivity of the right eye during the day
Vitals.DVPupilRtEyeMeasr 1 == 1
2 == 2
3 == 3
4 == 4
5 == 5
6 == 6
7 == 7
8 == 8
9 == 9
10 == 10
Vitals.DVPupilRtEyeMeasrUnkUnt 66 == Untestable
88 == Unknown
Only applicable to size
Vitals.DVSBP The highest systolic blood pressure for each day where vitals are recorded.
Vitals.DVSBPHighTime
Vitals.DVSBPLow The lowest systolic blood pressure for each day.
Vitals.DVSBPLowTime The time at which the lowest systolic blood pressure and its associated diastolic blood pressure is recorded.
Vitals.DVSpO2
Vitals.DVSpO2HighTime
Vitals.DVSpO2Low
Vitals.DVSpO2LowTime
Vitals.DVTempBrainC Brain temperature at the timepoint of the highest body temperature of the day, degrees Celsius.
Vitals.DVTempBrainNotDone
Vitals.DVTempBrainUnit F == F
C == C
Vitals.DVTempHighC The highest body temperature of the day in degrees Celsius. For the associated time point, see Vitals.DVTempHighDateTime. For location of where the temperature was measured, see Vitals.DVTempLocation.
Vitals.DVTempHighTime Time when the highest temp of the day was recorded.
Vitals.DVTempLocation 1 == External-axillary
2 == External-skin
3 == Core- rectal
4 == Core-bladder
5 == Core- oesophageal
6 == Core- tympanic
7 == Core- nasopharynx
Location of thermometer probe
Vitals.DVTempLowC The lowest temperature of a day in degrees Celsius. For the timepoint, see Vitals.DVTempLowDateTime. For location of where the temperature was measured, see Vitals.DVTempLocation.
Vitals.DVTempLowTime Time when the lowest temp of the day was recorded.
Vitals.DVTempNotDone
Vitals.DVTempUnitHigh C == C
F == F
The unit in which the temperature is measured
Vitals.DVTempUnitLow C == C
F == F
The unit in which the lowest body temperature of the day is measured.
Vitals.DVTimepoint 1 == Day 1
2 == Day 2
3 == Day 3
4 == Day 4
5 == Day 5
6 == Day 6
7 == Day 7
10 == Day 10
14 == Day 14
21 == Day 21
28 == Day 28
Intended day after injury when the vitals are recorded
Vitals.DVVitalsNotDone
Vitals.DVWorstPupilLftEyeMeasr
Vitals.DVWorstPupilLftEyeMeasrUnkUnt 66 == Untestable
88 == Unknown
Only applicable to size
Vitals.DVWorstPupilReactivityLghtLftEyeResult 1 == + (Brisk)
2 == + (Sluggish)
3 == - (Negative)
Vitals.DVWorstPupilReactivityLghtRghtEyeResult 1 == + (Brisk)
2 == + (Sluggish)
3 == - (Negative)
Vitals.DVWorstPupilRghtEyeMeasr
Vitals.DVWorstPupilRghtEyeMeasrUnkUnt 66 == Untestable
88 == Unknown
Only applicable to size
Vitals.DVWorstPupilSymmetry 1 == Equal
2 == Unequal R>L
3 == Unequal L>R
Vitals.HosComplEventHypocapnia 0 == No
1 == Single episode, short duration
2 == Multiple episodes or prolonged duration
88 == Unknown
Second Insults reported here relate to the the hospital phase (both ward and ICU). Definite hypocapnia is defined as a PaCO2 <=3.3 kPa (25 mmHg)
Vitals.HosComplEventHypotension 0 == No
1 == Single episode, short duration
2 == Multiple episodes or prolonged duration
88 == Unknown
Second Insults reported here relate to the the hospital phase (both ward and ICU). Pre-hospital hypoxia is documented at: InjuryHx.EDComplEventHypotension. Definite hypotension is defined as a documented systolic BP < 90 mm Hg (adults)
Vitals.HosComplEventHypoxia 0 == No
1 == Single episode, short duration
2 == Multiple episodes or prolonged duration
88 == Unknown
Second Insults reported here relate to the hospital phase (both ward and ICU). Pre-hospital hypoxia is documented at: InjuryHx.EDComplEventHypoxia. Definite hypoxia is defined as a documented PaO2 <8 kPa (60 mm Hg) and/or SaO2<90%
Vitals.HosComplEventSeizures 0 == No
1 == Single episode, short duration
2 == Partial/Focal
3 == Generalized
4 == Status epilepticus
5 == Silent seizure activity (only electrical, no clinical manifestation)
88 == Unknown
Vitals.HospSecondInsultsNeuroWorse 0 == No
1 == Yes
88 == Unknown
The importance of Neuroworsening was first described by Morris and Marshall. The occurrence of neuroworsening is related to poorer outcome in subjects with moderate to severe TBI. Neuroworsening is defined as 1) a decrease in GCS motor score of 2 or more points; 2) a new loss of pupillary reactivity or development of pupillary assymmetry >= 2mm; 3) deterioration in neurological or CT status sufficient to warrant immediate medical or surgical intervention
Vitals.HospSecondInsultsNeuroWorseAction 1 == None
2 == Unscheduled CT scan
3 == Change in medical therapy
4 == Surgical intervention
Vitals.HospSecondInsultsNeuroWorseYes 1 == Decrease in motor score >= 2 points
2 == Development of pupillary abnormalities
3 == Other neurological and/or CT deterioration
This variable provides a specification of the type of neuroworsening if it occurs.
Vitals.PatientLocation Ward == Ward
ICU == ICU