CENTER-TBI aims to advance the care for patients with traumatic brain injury (TBI), a field in medicine with one of the greatest unmet needs. Our research aims to:
Better characterize TBI as a disease, and describe it in a European context
Identify the most effective clinical interventions for managing TBI
- To collect high quality clinical and epidemiological data with repositories for neuro-imaging, DNA, and serum from patients with TBI.
- To refine and improve outcome assessment and develop health utility indices for TBI.
- To develop multidimensional approaches to characterisation and prediction of TBI.
- To define patient profiles which predict efficacy of specific interventions ("Precision Medicine").
- To develop performance indicators for quality assurance and quality improvement in TBI care.
- To validate the common data elements (CDEs) for broader use in international settings, and to develop a user-friendly web based data entry instrument and case report form builder.
- To develop an open source database compatible with FITBIR.
- To intensify networking activities and international collaborations in TBI.
- To disseminate study results and management recommendations for TBI to health care professionals, policy makers and consumers, aiming to improve health care for TBI at individual and population levels.
- To develop a "knowledge commons" for TBI, integrating CENTER-TBI outputs into systematic reviews.
Relationships between specific aims and work packages of CENTER-TBI